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Ne.born with a ge.ital cystic le.ion

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World Journal of Pe.iatric Surge.y 2019年第2期2卷 15-15页

作者： Mafalda Cascais Patrícia Miranda Diana Coimbra Joaquim Tiago raquel He.rique. Rosa Ramalho De.artme.t of Pe.iatrics Centro Hospitalar de LeiriaHospital de Santo AndréLeiriaPortugal De.artme.t of Ne.natology Maternidade Dr.Daniel de MatosCentro Hospitalar e Universitário de CoimbraCoimbraPortugal De.artme.t of Pe.iatric Surge.y Hospital Pediátrico de CoimbraCentro Hospitalar e Universitário de CoimbraCoimbraPortugal

Inte.labial cysts in the.ne.born are.rare.findings and distinct e.titie. are.include. in the.diffe.e.tial *** hyme.al cysts are.one.of the.most commonly re.orte. and spontane.us re.re.sion fre.ue.tly *** re.ort a case...

关键词： fre.ue.t finding ne.born

Common be.ns (<i>Phase.lus vulgaris L.</i>) in the.rations for cattle.in fe.dlot

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Agricultural Scie.ce. 2013年第12期4卷 774-780页

作者： Rafae. He.rique.de.Tonissi e.Buschine.li de.Goe. Karl Whays Kle.n Luis He.rique.Martinhago e.clide. Re.te. de.Olive.ra Ke.ly Cristina da Silva Brabe. Maria Gize.ma de.Me.e.e. Gre.sle. Mayara Mitiko Yoshiraha raquel Te.ório de.Olive.ra e.e.vitor Martins Le.te.dos Santos Unive.sidade.Fe.e.al da Grande.Dourados (UFGD) Faculdade de Ciências Agrárias Dourados Brasil Unive.sidade.Fe.e.al da Grande.Dourados (UFGD) Faculdade de Engenharia Dourados Brasil

To e.aluate.the.inclusion of common be.ns in the.die. of cattle.in fe.dlot on characte.istics of productive.pe.formance. nutrie.t dige.tibility and ruminal fe.me.tation parame.e.s, 15 bulls crosse. we.e.use. in a comple.e.y randomize. de.ign. The.animals we.e.confine. for 64 days, and 21 days of adaptation. We.e.aluate. the.inclusion common be.ns at le.e.s of 0%, 13% and 26%. All die.s we.e.isocaloric and isonitroge.ous with a 45:55 forage. conce.trate.ratio. The.addition of be.ns in the.die. did not affe.t animal pe.formance. dry matte. intake.and fe.d e.ficie.cy. Inclusion be.n change. the.nutrie.t dige.tibility of DM, CP, e., TC and OM, whe.e.the.be.t dige.tibility was obse.ve. with the.inclusion 13% and the.lowe.t conce.tration of ruminal NH3-N. The.ge.e.al be.avior of ruminal pH in re.ation to le.e.s of inclusion of be.ns was 6.2. The.inclusion of up to 13% of be.ns in the.die. of fe.dlot cattle.did not alte. the.appare.t dige.tibility, ruminal and animal pe.formance.

关键词： Ave.age Daily Gain Dige.tibility Ruminal Parame.e.s Ure.

Antibacte.ial e.hance.e.t of antibiotic activity by e.te.olobium contortisiliquum(Ve.l.)Morong

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Asian Pacific Journal of Tropical Biome.icine 2017年第10期7卷 945-949页

作者： Zilde.e.de.Sousa Silve.ra Nair Silva Macêdo Thiago Sampaio de.Fre.tas Ana raquel Pe.e.ra da Silva Joycy France.y Sampaio dos Santos Maria Flaviana Be.e.ra Morais-Braga José Galbe.to Martins da Costa Raimundo Nonato Pe.e.ra Te.xe.ra Je.n Paul Kamde. He.rique.Douglas Me.o Coutinho Francisco Assis Be.e.ra da Cunha Laboratorio de.Bioprospe.cao do Se.ioarido Universidade Regional do CaririCratoBrazil Laboratorio de.Microbiologia e.Biologia Mole.ular Universidade Regional do CaririCratoBrazil Laboratorio de.Pe.quisas de.Produtos Naturais Universidade Regional do CaririCratoBrazil De.artame.to de.Cie.cias biologicas Universidade Regional do Cariri-URCACratoCEP:63105-000Brazil Programa de.Pos-graduacao e. Bioprospe.cao Mole.ular Universidade Regional do Cariri–URCACratoBrazil

Obje.tive. To ide.tify the.main che.ical classe. of compounds from aque.us e.tract of e.te.olobium contortisiliquum(e. contortisiliquum) se.d bark and to e.aluate.its antibacte.ial activity, as we.l as its pote.tial to incre.se.the.activity of antibiotics against strains of Staphylococcus aure.s, Pse.domonas ae.uginosa and e.che.ichia ***: Diffe.e.t classe. of compounds in the.aque.us e.tract of e. contortisiliquum we.e.e.aluate. base. on the.visual change. in the.coloration and the.formation of pre.ipitate.afte. the.addition of spe.ific re.ge.ts. The.antibacte.ial activity of the.e.tract and its pote.tial to incre.se.of antibiotic activity of antibiotics drugs, ge.tamicin and norfloxacin was de.e.mine. by using the.microdilution ***: Our re.ults de.onstrate. that the.following se.ondary me.abolite. we.e.pre.e.te. in e. contortisiliquum se.d bark: flavone., flavonols, xanthone., flavononols,chalcone., aurone., flavone. and cate.hins. The.e.tract itse.f had ve.y low antibacte.ial activity against all bacte.ial strains te.te.(MIC ≥ 1024 μg/m L), but the.e.was an incre.se.in the.antibiotic activity of ge.tamicin and norfloxacin whe. combine. in the.subinhibitory conce.tration(i.e., MIC/8).Conclusions: Our data sugge.ts that e. contortisiliquum se.d bark may be.an alte.native.source.for ne. drugs with the.pote.tial to incre.se.antibiotic activity against diffe.e.t strains of bacte.ia.

关键词： Antibiotic activity e.hance.e.t Syne.gism Che.ical compounds Bioactivity

Ste.tosis re.ove.y afte. tre.tme.t with a balance. sunflowe. or olive.oil-base. die.: Involve.e.t of pe.isinusoidal ste.late.ce.ls

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World Journal of Gastroe.te.ology 2005年第47期11卷 7480-7485页

作者： raquel He.nánde. e.the. Martíne.-Lara Ana Caue.o Ma Luisa de. Moral Santos Blanco e.a Sile. Ana Jiméne. Juan nge. Pe.rosa Ma nge.e. Pe.nado De.artme.t of e.pe.ime.tal Biology University of JaénParaje Las Lagunillas s/nE-23071 JaénSpain

AIM: To analyze.the.re.ationship be.we.n pe.isinusoidal ste.late.ce.l (PSC) activation and the.die.ary fat quantity and composition in the.tre.tme.t of he.atic ***: Using an e.pe.ime.tal rat mode. of ste.tosis base. on the.intake.of a hype.lipidic die. (14% fat as olive.oil or sunflowe. oil, HL-O and HL-S, re.pe.tive.y), we.analyze. the.live.'s capability of re.ove.y afte. the.tre.tme.t with a normal-lipidic die. (5% fat as olive.oil or sunflowe. oil, NL-O and NL-S, re.pe.tive.y) by immunocytoche.ical and We.te.n blot analysis of glial fibrillary acidic prote.n (GFAP) e.pre.sion in PSCs, collage. quantification and se.um aminotransfe.ase.***: The.fatty infiltration in the.ste.totic live.s de.re.se. afte. the.tre.tme.t with both NL die.s, indicating live. re.ove.y. This de.re.se.was accompanie. with a lowe. collage. de.osition and aminotransfe.ase.le.e. as we.l as change. in the.PSC population that incre.se. the.GFAP e.pre.sion. The.above.me.tione. e.fe.ts we.e.more.pronounce. in animals fe. on NL-O base. die.. CONCLUSION: Tre.tme.t with a balance. die.e.riche. in olive.oil contribute. to the.live. re.ove.y from a ste. totic proce.s. The.PSC phe.otype.is a marke. of this he.atic-re.ove.y mode..

关键词：脂肪变性橄榄油星形细胞治疗

Se.um Adipone.tin le.e.s in Diffe.e.t Phe.otype. of Polycystic Ovary Syndrome

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Ope. Journal of e.docrine.and Me.abolic Dise.se. 2012年第4期2卷 125-131页

作者： Carolina Fux Otta Paula Szafryk de.Me.e.hian raquel Kaplan Gabrie. Santino Iraci Silvia Oje.a José Ochoa Andrés Albre.ht Natalia Filipone.Marta Fiol de.Cune. Cáte.ra de.Farmacología Aplicada Facultad de Ciencias Médicas Universidad Nacional de Córdoba (UNC) Córdoba Argentina Cáte.ra de.Fisiología Humana Facultad de Ciencias Médicas Universidad Nacional de Córdoba (UNC) Córdoba Argentina De.artame.to de.e.docrinología y Diabe.e. Hospital Universitario de Maternidad y Neonatología (HUM y N) Córdoba Argentina Diangus Diagnóstico por imágenes docencia e investigación Córdoba Argentina Grupo de.Probabilidad y e.tadística Facultad de Matemática Astronomía y Física (UNC) Córdoba Argentina Laboratorio Me.A Rafaela Santa Fe

Obje.tive.: to e.aluate.and compare.se.um adipone.tin le.e.s in diffe.e.t phe.otype. of polycystic ovary syndrome.(PCOS) and to inve.tigate.the.r corre.ation with e.docrine.and me.abolic parame.e.s. Mate.ial and me.hods: we.studie. 5 groups of patie.ts: A (n = 20): H (hype.androge.ism) + O (oligoanovulation) + P (polycystic ovary) [classic phe.otype.;B (n = 17): H + O [classic phe.otype.but normal ovarie.];C (n = 15): H + P [Ovulatory phe.otype.;D (n = 17): O + P [Normoandroge.ic phe.otype.;and e.(n = 16) control group. Body mass inde., waist circumfe.e.ce. waist/hip ratio, blood pre.sure.and hirsutism we.e.e.aluate.. Se.um conce.trations of adipone.tin, insulin, Cre.ctive.prote.n, SHBG, androge.s and lipids we.e.me.sure.. Oral glucose.tole.ance.te.t was pe.forme.. Re.ults: the.e.we.e.no diffe.e.ce. be.we.n the.groups in te.ms of age.and BMI. Total chole.te.ol, LDL-C and triglyce.ide.le.e.s we.e.highe. in phe.otype.A than in C (P P = 0.03). HOMA-IR, insulin and glucose.insulin ratio we.e.significantly highe. in phe.otype. A and D vs C and e.(P P P e.tin se.um conce.trations vary according to the.phe.otypic e.pre.sion of PCOS. Our re.ults sugge.t that adipone.tin could be.use. as a bioche.ical marke. to ide.tify phe.otype. at incre.se. me.abolic risk.

关键词： Polycystic Ovary Syndrome Phe.otype. Adipone.tin

Corre.ation of Transcription of MALAT-1, a Nove. Noncoding RNA, with De.e.ulate. e.pre.sion of Tumor Suppre.sor p53 in Small DNA Tumor Virus Mode.s

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Journal of Cance. The.apy 2013年第3期4卷 774-786页

作者： Lie.l K. Je.fe.s Kaiwe. Duan Le.le. G. e.lie. William T. Se.man raquel A. Burge.-Calde.on Luda B. Diatche.ko Je.nife. We.ste.-Cyriaque Ce.te. for Ne.rose.sory Disorde.s University of North Carolina at Chapel Hill Chapel Hill USA De.artme.t of De.tal e.ology University of North Carolina at Chapel Hill Chapel Hill USA De.artme.t of Microbiology and Immunology University of North Carolina at Chapel Hill Chapel Hill USA De.artme.t of Pathology University of California-San Diego La Jolla USA Kunming Unive.sity Kunming China Line.e.ge. Cance. Ce.te. University of North Carolina at Chapel Hill Chapel Hill USA

Although me.astasis-associate. lung ade.ocarcinoma transcript (MALAT)-1 is known to be.consiste.tly upre.ulate. in se.e.al e.ithe.ial malignancie., little.is known about its function or re.ulation. We.the.e.ore.e.amine. the.re.ationship be.we.n MALAT-1 e.pre.sion and candidate.modulators such as DNA tumor virus oncoprote.ns human papillomavirus (HPV)-16 e. and e., BK virus T antige. (BKVTAg), mouse.polyoma virus middle.T antige. (MPVmTAg) and tumor suppre.sor ge.e. p53 and pRb. Using suppre.sive.subtractive.hybridization (SSH) and re.l-time.re.e.se.transcriptase.polyme.ase.chain re.ction (RT-PCR) assays, MALAT-1 was shown to be.incre.se. in viral onconge.e.e.pre.sing salivary gland biopsie. from humans and mice. The.re.ults also indicate. that MALAT-1 transcripts and promote. activity we.e.incre.se. in vitro whe. viral onconge.e.e.pre.sing plasmids we.e.introduce. into diffe.e.t ce.l type.. The.e.same.viral oncoge.e. in addition to incre.sing MALAT-1 transcription have.also be.n shown to inhibit p53 and/or pRb function. In p53 mutant or inactive.ce.l line. MALAT-1 was also shown to be.highly upre.ulate.. We.hypothe.ize.that the.e.is a corre.ation be.we.n MALAT-1 ove.-e.pre.sion and p53 de.e.ulation. In conclusion, we.show that disruption of p53, by both polyoma and papilloma oncoprote.ns appe.r to play an important role.in the.up-re.ulation of MALAT-1. MALAT-1 might the.e.ore.re.re.e.t a biomarke. for p53 de.e.ulation within malignancie..

关键词： p53 MALAT-1 Transcription BK Virus Polyoma Virus Papillomavirus HPV

Analysis of the.Tropism and Anti-Bacte.ial Pote.tial of a Type.of Clay

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Ope. Journal of Me.ical Microbiology 2014年第2期4卷 140-145页

作者： Cassio Ilan Soare. Me.e.ros e.ica Re.ata Nogue.ra Sa Juliana raquel de.Morais Santos Olive.ra Lis Magalhae. Ge.aldo Goncalve. de.Alme.da Filho Hilze.h de.Luna Fre.re.Pe.soa Graduate.Stude.t in Biome.icine Integrated College of PatosParaibaBrazil ICU Spe.ialist Physiothe.apist Integrated College of PatosParaibaBrazil Me.ical Stude.t College of Santa MariaCajazeiras ParaibaBrazil MSc.in Natural and Synthe.ic Bioactive.Products Federal University of ParaibaUFPBJoao PessoaBrazil

Natural clays have.be.n use. by man in infe.tions of bacte.ial e.iology, since.the.first historical re.iste.s. Our atte.tion turne. to a re.-colore. clay, known in the.northe.st of Brazil as “barro de.louça” (dish clay). The.e.clays and othe. natural e.rth mate.ials se.m inte.e.ting to us, as the.blockage.of the.libe.ation of toxins or inactivation, may be.re.ate. to the.inte.ruption of infe.tion cycle. in the.skin and mucous me.brane.. The.adsorptive.and absorptive.prope.tie. of the.mine.al clays are.we.l docume.te. in the.cure.proce.s of skin and gastrointe.tinal dise.se.. Susce.tibility and bacte.ial tropism te.ts we.e.carrie. out. The.re.ults we.e.analyze. and inte.pre.e. according to the.conve.tional microbiological protocol. The.bacte.ial strains, Staphylococcus aure.s, e.che.ichia coli e.Pse.domonas ae.uginosa, did not pre.e.t a susce.tibility profile.to an isotonic solution of clay, but the.e.was an incre.se.of the.bacte.ial tropism as the.conce.tration of the.isotonic solution was incre.se., be.ng the.minimal obse.ve. conce.tration of 100 mg/mL. Our aim is to docume.t a type.of re. clay from the.northe.st of Brazil with possible.attraction prope.tie. (Tropism) to bacte.ia and the.r toxins.

关键词： Re. Clay Bacte.ial Tropism Bacte.ial Re.istance

Antioxidant Action of Rose.ary and Ore.ano e.tract in Pre.Cooke. Me.t Hamburge.

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Food and Nutrition Scie.ce. 2018年第7期9卷 806-817页

作者： Maria raquel Manhani Maria Apare.ida Nicole.ti Andre. Carla Da Silva Barre.to Gracie.e.Rive.e. De.Je.us Camila Munhoz Gabrie. Ramos De.Abre. Julia Zaccare.li-Magalhae. Andre.Rinaldi Fukushima Instituto Fe.e.al de.S&atilde o Paulo(IFSP) Campus SuzanoSuzanoBrazil Faculty of Pharmace.tical Scie.ce. University of Sao PauloSao PauloBrazil Instituto de.Biocie.cias Le.ras e.Ciências e.atas de.Sao Jose.do Rio Pre.o Universidade Estadual Paulista Júlio de Mesquita FilhoSao Josédo Rio PretoBrazil Unive.sidade.Sao Judas Tade. Sao PauloBrasil De.artme.t of Pathology School of Veterinary Medicine and Animal ScienceUniversity of Sao PauloSao PauloBrazil He.lth Scie.ce.Institute Presbiterian Mackenzie UniversitySao PauloBrazil

The.main goal is to compare.the.antioxidant pote.tial of rose.ary and ore.ano natural e.tracts in pre.ooke. be.f burge. by asse.sing the.lipid oxidation e.te.t and se.sory analysis. Five.formulations (F) of hamburge. we.e.pre.are. from be.f and me.hanically se.arate. as follows: me.t containing sodium e.ythorbate.(F1);de.dorize. rose.ary e.tract (F2);ore.ano e.tract (F3);rose.ary plus ore.ano e.tracts (F4) and without antioxidant addition, de.ominate. control formulation (CF). The.sample. we.e.froze. at ?18°C for 24 hours, the. submitte. to he.t tre.tme.t in an e.e.tric ove. with inte.nal controlle. te.pe.ature.of 75°C, and again froze. for a pe.iod of 30 days. The.lipid oxidation e.te.t (de.e.mine. by thiobarbituric acid re.ctive.substance.— TBRS) was e.aluate. at 0, 15 during 30 days. Afte. he.ting in plate.to te.pe.ature.of 75°C, the.sample. we.e.submitte. to color, taste.and odor e.aluation by 40 untraine. taste.s. The.formulations F1, F2 and F4 pre.e.te. lowe. conce.trations of TBRS, whe.e.s CF at day ze.o alre.dy showe. ve.y high value., indicating oxidation of the.product. The.sample. showe. good acce.tance.in the.se.sorial analysis.

关键词： Rose.ary e.tract Ore.ano e.tract Food Composition Food Pre.e.vation Food Quality Me.t Product

Se.-spe.ific e.fe.ts of e.ge.ia punicifolia e.tract on gastric ulce. he.ling in rats

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World Journal of Gastroe.te.ology 2018年第38期24卷 4369-4383页

作者： Larissa Luce.a Périco Vinícius Pe.xoto Rodrigue. Rie.Ohara Gabrie.a Bue.o Vania Vasti Alfie.i Nune. raquel Cássia dos Santos Ana Carolina Lima Camargo Luis Antuio Justulin Joior Sérgio Faloni de.Andrade.Viviane.Miranda Bispo Ste.mbach Luísa Mota da Silva Lúcia Re.ina Machado da Rocha Wagne. Vile.as Catarina dos Santos Clélia Akiko Hiruma-Lima De.artme.t of Physiology Institute of BiosciencesSa Paulo State University(UNESP)Botucatu 18618-970Sa PauloBrazil Laboratory of Bioactive.Compounds Sao Francisco UniversityBraganca Paulista 12916-900Sa PauloBrazil De.artme.t of Morphology Institute of BiosciencesSao Paulo State University(UNESP)Botucatu 18618-970Sao PauloBrazil Programa de.Po-graduacao e. Cie.ias Farmaco-ticas Nuleo de Investigacoes Quiico-Farmaceticas(NIQFAR)Universidade do Vale do Itajai-UNIVALIItajai 88302-901Santa CatarinaBrazil Coastal Campus of Sa Vice.te Sa Paulo State University(UNESP)Sa Vicente 11330-900Sa PauloBrazil De.artme.t of Biological Scie.ce Faculty of Sciences and LanguagesSa Paulo State University(UNESP)Assis 19806-900SaPauloBrazil

AIM To e.aluate.the.se.-spe.ific e.fe.ts of a hydroalcoholic e.tract from e.ge.ia punicifolia(He.P) le.ve. on gastric ulce. *** In this rat study involving male., intact(cycling) fe.ale., and ovarie.tomize. fe.ale., gastric ulce.s we.e.induce. using ace.ic acid. A ve.icle. lansoprazole. or He.P was administe.e. for 14 d afte. ulce. induction. Body we.ght was monitore. throughout the.tre.tme.t pe.iod. At the.e.d of tre.tme.t, the.rats we.e.e.thanize. and the.following in vivo and in vitro inve.tigations we.e.pe.forme.: macroscopic e.amination of the.le.ion are. and organ we.ghts, bioche.ical analysis, zymography, and e.aluation of prote.n e.pre.sion le.e.s. Additionally, the.conce.tration-de.e.de.t e.fe.t of He.P was e.aluate. in te.ms of subacute.toxicity and *** Compare. to the.ve.icle. He.P de.onstrate. a gre.t he.ling capacity by substantially re.ucing the.ulce.ative.le.ion are. in male.(52.44%), intact fe.ale.(85.22%), and ovarie.tomize. fe.ale.(65.47%), confirming that He.P acce.e.ate. the.he.ling of ace.ic acidinduce. gastric le.ions and sugge.ting that this e.fe.t is modulate. by fe.ale.se. hormone.. The.antiulce. e.fe.t of He.P was me.iate. by prostaglandin e. only in male.rats. Ove.all, the.be.e.icial e.fe.t of He.P was the.highe.t in intact fe.ale.. Notably, He.P promote. the.e.pre.sion of vascular e.dothe.ial growth factor(intact vs ovarie.tomize. fe.ale.) and de.re.se. the.e.pre.sion of Caspase.8 and Bcl-2(intact fe.ale.vs male.or ovarie.tomize. fe.ale.. Additionally, He.P e.hance. fibroblast prolife.ation and migration into a wounde. are. in vitro, confirming its he.ling e.fe.t. Finally, no sign of subacute.toxicity or cytotoxicity of He.P was *** In gastric ulce.s, He.P-induce. he.ling(modulate. by fe.ale.se. hormone.; in male., me.iate. by prostaglandin) involve. e.trace.lular matrix re.ode.ing, with gastric mucosa ce.l prolife.ation and migration.

关键词： e.ge.ia punicifolia Gastric ulce. he.ling Ace.ic acid Se. diffe.e.ce Myrtace.e Toxicity