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Leveraging ROTI map derived from Indonesian GnSS receiver network for advancing study of Equatorial Plasma Bubble in Southeast/East Asia

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Earth and Planetary Physics 2025年第1期9卷 101-116页

作者： Prayitno Abadi Ihsan n.Muafiry Teguh n.Pratama Angga y.Putra Suraina Gatot H.Pramono Sidik T.Wibowo Febrylian F.Chabibi Umar A.Ahmad Wildan P.Tresna Asnawi Research Center for Climate and Atmosphere Indonesian National Research and Innovation Agency(BRIN)BandungIndonesia School of Electrical Engineering Telkom UniversityBandungIndonesia Directorate of Laboratory Management Facilities and Science and Technology Park Indonesian National Research and Innovation Agency(BRIN)PontianakIndonesia Geophysics Laboratory Master Program in PhysicsUniversitas Gadjah Mada(UGM)YogyakartaIndonesia Research Center for Space Indonesian National Research and Innovation Agency(BRIN)BandungIndonesia Indonesian Geospatial Information Agency(BIG) JakartaIndonesia Research Center for Photonics Indonesian National Research and Innovation Agency(BRIN)Tangerang SelatanIndonesia Department of Earth and Planetary Sciences Hokkaido UniversitySapporoJapan

This paper highlights the crucial role of Indonesia’s GnSS receiver network in advancing Equatorial Plasma Bubble(EPB)studies in Southeast and East Asia,as ionospheric irregularities within EPB can disrupt GnSS signals and degrade positioning *** by the Indonesian Geospatial Information Agency(BIG),the Indonesia Continuously Operating Reference Station(Ina-CORS)network comprises over 300 GnSS receivers spanning equatorial to southern low-latitude ***-CORS is uniquely situated to monitor EPB generation,zonal drift,and dissipation across Southeast *** provide a practical tool for EPB research,by sharing two-dimensional rate of Total Electron Content(TEC)change index(ROTI)derived from this *** generate ROTI maps with a 10-minute resolution,and samples from May 2024 are publicly available for further scientific *** preliminary findings from the ROTI maps of Ina-CORS are ***,the Ina-CORS ROTI maps reveal that the irregularities within a broader EPB structure persist longer,increasing the potential for these irregularities to migrate farther ***,we demonstrate that combined ROTI maps from Ina-CORS and GnSS receivers in East Asia and Australia can be used to monitor the development of ionospheric irregularities in Southeast and East *** have demonstrated the combined ROTI maps to capture the development of ionospheric irregularities in the Southeast/East Asian sector during the G5 Geomagnetic Storm on May 11,*** observed simultaneous ionospheric irregularities in Japan and Australia,respectively propagating northwestward and southwestward,before midnight,whereas Southeast Asia’s equatorial and low-latitude regions exhibited irregularities *** sharing ROTI maps from Indonesia and integrating them with regional GnSS networks,researchers can conduct comprehensive EPB studies,enhancing the understanding of EPB behavior across Southeast and East Asia and contributing significantly to ionosphe

关键词： Equatorial Plasma Bubble(EPB) GnSS receivers’network Indonesia Continuously Operating Reference Station(Ina-CORS) ionospheric map Rate of TEC change index(ROTI)map

Hepatoprotective and antioxidant capacity of Melochia corchorifolia extracts

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Asian Pacific Journal of Tropical Medicine 2013年第7期6卷 537-543页

作者： B Ganga rao y Venkateswara rao T Mallikarjuna rao A.U College of Pharmaceutical Sciences Andhra UniversityVisakhapatnamAndhra PradeshIndia-530003 Department of Botany College of Science and TechnologyAndhra University.VisakhapatnamAndhra PradeshIndia-530003

Objective:To evaluate bepato protective and antioxidant capacity of Melochia corchorifolia （***）aerial part ***:Antioxidant activitywas evaluated by using three free radicals（Superoxide,Hydroxyl and DPPH） and hepatoprotective activity was assessed against CCl4 induced liver intoxication in ***:The extracts produced concentration dependent percentage protection in decrease of serum enzymes and percentage inhibition on free *** all extracts methanol extract showed better activity with percentage protection of SGOT（78.98%）,SGPT（79.65%）,ALP（82.48%） and total bilirubin（80.0%）levels against CCl4 liver intoxication and also methanolic extract showed better activity with IC50 values on superoxide. hydroxyl and DPPH radicals were 127μg.240μg and 179μ***:From the results obtained during the study it could be concluded that *** aerial part extracts have antioxidant and hepaloprotective *** study is necessary for isolation and characterization of bioactive molecules which are responsible for hepatoprotective and antioxidant activity.

关键词： Melochia corchorifolia Aerial parts Free radicals Antioxidant Activity CCl_4 Hepatoprotective activity

Impacts of PI3K/protein kinase B pathway activation in reactive astrocytes: from detrimental effects to protective functions

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neural Regeneration Research 2025年第4期20卷 1031-1041页

作者： Ramón Pérez-núñez María Fernanda González Ana María Avalos Lisette Leyton Cellular Communication Laboratory Programa de Biología Celular y MolecularCenter for Studies on ExerciseMetabolism and Cancer(CEMC)Instituto de Ciencias Biomédicas(ICBM)Facultad de MedicinaUniversidad de ChileSantiagoChile Advanced Center for Chronic Diseases(ACCDiS) Faculty of Chemical and Pharmaceutical Sciences&Faculty of MedicineUniversidad de ChileSantiagoChile Instituto de Ciencias Biomédicas Facultad de Ciencias de la SaludUniversidad Autónoma de ChileSantiagoChile

Astrocytes are the most abundant type of glial cell in the central nervous *** injury and inflammation,astrocytes become reactive and undergo morphological and functional *** on their phenotypic classification as A1 or A2,reactive astrocytes contribute to both neurotoxic and neuroprotective responses,***,this binary classification does not fully capture the diversity of astrocyte responses observed across different diseases and *** analysis has revealed that reactive astrocytes have a complex landscape of gene expression profiles,which emphasizes the heterogeneous nature of their *** actively participate in regulating central nervous system inflammation by interacting with microglia and other cell types,releasing cytokines,and influencing the immune *** phosphoinositide 3-kinase(PI3K)/protein kinase B(AKT)signaling pathway is a central player in astrocyte reactivity and impacts various aspects of astrocyte behavior,as evidenced by in silico,in vitro,and in vivo *** astrocytes,inflammatory cues trigger a cascade of molecular events,where nuclear factor-κB serves as a central mediator of the pro-inflammatory ***,we review the heterogeneity of reactive astrocytes and the molecular mechanisms underlying their *** highlight the involvement of various signaling pathways that regulate astrocyte reactivity,including the PI3K/AKT/mammalian target of rapamycin(mTOR),αvβ3 integrin/PI3K/AKT/connexin 43,and notch/PI3K/AKT *** targeting the inactivation of the PI3K/AKT cellular signaling pathway to control reactive astrocytes and prevent central nervous system damage,evidence suggests that activating this pathway could also yield beneficial *** dual function of the PI3K/AKT pathway underscores its complexity in astrocyte reactivity and brain function *** review emphasizes the importance of employing astrocyte-exclusive models to underst

关键词： inflammation integrins neuroprotective neurotoxic phosphatidylinositol 3-kinase reactive astrocytes signal transduction Thy-1(CD90)

Artificial neural network approach for prediction of stress–strain curve of near b titanium alloy

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Rare Metals 2014年第3期33卷 249-257页

作者： Srinivasu Gangi Setti R.n.rao Mechanical Engineering National Institute of Technology

In the present study, artificial neural network（Ann） approach was used to predict the stress-strain curve of near beta titanium alloy as a function of volume fractions of a and b. This approach is to develop the best possible combination or neural network（nn） to predict the stress-strain curve. In order to achieve this, three different nn architectures（feed-forward back-propagation network,cascade-forward back-propagation network, and layer recurrent network）, three different transfer functions（purelin, Log-Sigmoid, and Tan-Sigmoid）, number of hidden layers（1 and 2）, number of neurons in the hidden layer（s）,and different training algorithms were employed. Ann training modules, the load in terms of strain, and volume fraction of a are the inputs and the stress as an *** system was trained using the prepared training set（a,16 % a, 40 % a, and b stress-strain curves）. After training process, test data were used to check system accuracy. It is observed that feed-forward back-propagation network is the fastest, and Log-Sigmoid transfer function is giving the best results. Finally, layer recurrent nn with a single hidden layer consists of 11 neurons, and Log-Sigmoid transfer function using trainlm as training algorithm is giving good result, and average relative error is1.27 ± 1.45 %. In two hidden layers, layer recurrent nn consists of 7 neurons in each hidden layer with trainrp as the training algorithm having the transfer function of LogSigmoid which gives better results. As a result, the nn is founded successful for the prediction of stress-strain curve of near b titanium alloy.

关键词： Artificial neural network (Ann) Stressstrain curve Titanium alloys

Separation of Metallic and Semiconducting Single-Walled Carbon nanotubes Through Fluorous Chemistry

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nano Research 2009年第3期2卷 183-191页

作者： Sandeep Ghosh n.R.rao Chemistry and Physics of Materials Unit DST unit on Nanoscience and CSIR Centre of Excellence in ChemistryJawaharlal Nehru Centre for Advanced Scientifi c ResearchJakkur P.O.Bangalore-560064India Solid State and Structural Chemistry Unit Indian Institute of ScienceBangalore-560012India

Separation of metallic from semiconducting single-walled carbon nanotubes has been a major challenge for some time and some previous efforts have resulted in partial success. We have accomplished the separation effectively by employing fl uorous chemistry wherein the diazonium salt of 4-heptadecafl uorooc tylaniline selectively reacts with the metallic nanotubes present in the mixture of nanotubes. The resulting fl uoroderivative was extracted in perfl uorohexane leaving the semiconducting nanotubes in the aqueous layer. The products have been characterized by both Raman and electronic absorption spectroscopy. The method avoids the cumbersome centrifugation step required by some other procedures.

关键词： Carbon nanotubes metallic semiconducting fl uorous separation

Chloride binding and time-dependent surface chloride content models for fly ash concrete

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Frontiers of Structural and Civil Engineering 2016年第1期10卷 112-120页

作者： S. MUTHULInGAM B. n. rao Department of Civil Engineering SSN College of Engineering Kalavakkam 603 110 India Structural Engineering Division Department of Civil Engineering Indian Institute of Technology Madras Chennai 600 036 India

Corrosion of embedded rebars is a classical deterioration mechanism of reinforced concrete structures exposed to chloride environments. Such environments can be attributed to the presence of seawater, deicing or sea-salts, which have high concentrations of chloride ion. Chloride ingress into concrete, essential for inducing rebar corrosion, is a complex interaction between many physical and chemical processes. The current study proposes two chloride ingress parameter models for fly ash concrete, namely： 1） surface chloride content under tidal exposure condition; and 2） chloride binding. First, inconsistencies in surface chloride content and chloride binding models reported in literature, due to them not being in line with past research studies, are pointed out. Secondly, to avoid such inconsistencies, surface chloride content and chloride binding models for fly ash concrete are proposed based upon the experimental work done by other researchers. It is observed that, proposed models are simple, consistent and in line with past research studies reported in literature.

关键词： binding isotherms chloride ingress concrete fly ash surface chloride content

Quantum counterfactuality with identical particles

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Communications in Theoretical Physics 2023年第6期75卷 59-65页

作者： Vinod n rao Anindita Banerjee R Srikanth Theoretical Sciences Division Poornaprajna Institute of Scientific ResearchBidalurBengaluru—562164India Graduate Studies Manipal Academy of Higher EducationManipal—576104India Centre of Development of Advanced Computing Corporate Research and DevelopmentPune—411008India

Quantum self-interference enables the counterfactual transmission of information,whereby the transmitted bits involve no particles traveling through the *** this work,we show how counterfactuality can be realized even when the self-interference is replaced by interference between identical ***,the facet of indistinguishability called forth here is associated with first-order coherence,and is different from the usual notion of indistinguishability associated with the(anti-)commutation relations of mode *** an experimental perspective,the simplest implementation of the proposed idea can be realized by slight modifications to existing protocols for differential-phase-shift quantum key distribution or interaction-free measurement.

关键词： quantum cryptography counterfactuality indistinguishability

How would preclinical Alzheimer’s disease (AD pathology) occur? An insight from a genomic instability mouse model

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neural Regeneration Research 2021年第10期16卷 2012-2014页

作者： Chinthalapally V.rao Hiroshi y.yamada Center for Cancer Prevention and Drug Development Department of MedicineHematology/Oncology SectionUniversity of Oklahoma Health Sciences Center(OUHSC)Oklahoma CityOKUSA

More than 95%of Alzheimer’s disease(AD)is late-onset,in which patients show clinical cognition/behavior symptoms after age *** early-onset AD that comes with mutations in genes directly involved in amyloid metabolism(APP,PSEn),genetic predispositions associated with late-onset AD are harder to pinpoint,and their mechanistic links to AD development need further *** the development mechanism of late-onset AD remains controversial,amyloid-beta accumulation,initiated in middle age,is widely accepted as the triggering event for early AD pathology(Du Bois et al.,2010;Sterling et al.,2011).

关键词： clinical Alzheimer metabolism

Control of petroleum-hydrocarbon contaminated groundwater by intrinsic and enhanced bioremediation

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Journal of Environmental Sciences 2010年第6期22卷 864-871页

作者： Chih-Ming Kao rao y.Surampalli Mu-Sheng Lee Institute of Environmental Engineering "National" Sun Yat-Sen University U.S.Environmental Protection Agency Environmental Protection Bureau Kaohsiung City Government

In the first phase of this study, the effectiveness of intrinsic bioremediation on the containment of petroleum hydrocarbons was evaluated at a gasoline spill site. Evidences of the occurrence of intrinsic bioremediation within the BTEX （benzene, toluene, ethylbenzene, and xylenes） plume included （1） decreased BTEX concentrations; （2） depletion of dissolved oxygen （DO）, nitrate, and sulfate; （3） production of dissolved ferrous iron, methane, and CO2; （4） deceased pH and redox potential; and （5） increased methanogens, total heterotrophs, and total anaerobes, especially within the highly contaminated areas. In the second phase of this study, enhanced aerobic bioremediation process was applied at site to enhance the BTEX decay rates. Air was injected into the subsurface near the mid-plume area to biostimulate the naturally occurring microorganisms for BTEX biodegradation. Field results showed that enhanced bioremediation process caused the change of BTEX removal mechanisms from anaerobic biodegradation inside the plume to aerobic biodegradation. This variation could be confirmed by the following field observations inside the plume due to the enhanced aerobic bioremediation process：（1） increased in DO, CO2, redox potential, nitrate, and sulfate, （2） decreased in dissolved ferrous iron, sulfide, and methane, （3） increased total heterotrophs and decreased total anaerobes. Field results also showed that the percentage of total BTEX removal increased from 92% to 99%, and the calculated total BTEX first-order natural attenuation rates increased from 0.0092% to 0.0188% per day, respectively, after the application of enhanced bioremediation system from the spill area to the downgradient area （located approximately 300 m from the source area）.

关键词： petroleum hydrocarbon groundwater natural attenuation intrinsic bioremediation