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Homeostatic relevance of vitamin D in maintaining male fertility in human: Down-regulation of oxidative stress and up-regulation of anti-oxidative defense and steroidal hormones

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Asian pacific Journal of Reproduction 2018年第2期7卷 56-61页

作者： Fahad Hussain Arif Malik muhammad Saeed Qureshi muhammad Imran Sulayman Waquar Hassan Shafique Zohaib rana Hnin Ei Thu Zahid Hussain Institute of Molecular Biology and Biotechnology The University of LahoreRaiwind Road55150LahorePakistan Department of Biochemistry Akhtar Saeed Medical and Dental CollageLahorePakistan Department of Physiology Nishtar Medical University66000MultanPakistan Department of Biochemistry University of AgricultureFaisalabad38040Pakistan Department of Pharmacology Faculty of MedicineUniversiti Kebangsaan MalaysiaJalan Yaacob LatifBandar Tun Razak56000CherasKualaLumpurMalaysia Department of Pharmaceutics Faculty of PharmacyUniversiti Teknologi MARAPuncak Alam CampusBandar Puncak Alam42300SelangorMalaysia

Objective:To evaluate correlation between the levels of vitamin D and male infertility as well as to determine the efficacy of vitamin D in improving the male fertility by up-regulating the levels of testosterone and ***: In the present study, 130 male patients (aged 25-70 years) having fertility defects were screened and 145 healthy individuals were taken as control. All human subjects were screened for 4-hydroxynonenal, isoprostane-F2α, 8-hydroxy-2′-deoxyguanosine, vitamin D, luteinizing hormone, follicle stimulating hormone, testosterones, malondialdehyde, superoxide dismutase, catalase, glutathione peroxidase, and nitric ***: The screening analysis revealed that the levels of luteinizing hormone, follicle stimulating hormone, and testosterone were lower in male infertile subjects compared to healthy subjects. Similarly, the levels of vitamin D [(17.17 ± 2.30) ng/mL] and calcium[(6.29 ± 0.31) mg/dL] were significantly lower in infertile groups compared to the normal healthy groups. Moreover, the study revealed that the levels of superoxide dismutase, catalase, and glutathione peroxidase were significantly higher in healthy subjects compared to the infertile ***:Vitamin D exhibits strong relevance to male fertility by maintaining the levels of sex hormones (luteinizing hormone, follicle stimulating hormone, and testosterone), up-regulating the antioxidant defense (superoxide dismutase, catalase, and glutathione peroxidase), and down-regulating the oxidative stress (malondialdehyde, nitric oxide, and inducible nitric oxide synthase species).

关键词： Vitamin D Male fertility Luteinizing hormone Follicle-stimulating hormone Testosterone Oxidative stress Spermatogenesis

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Assessment of Runoff, Sediment Yields and Nutrient Loss Using the Swat Model in Upper Indus Basin of Pakistan

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Journal of Geoscience and Environment Protection 2020年第9期8卷 62-81页

作者： Washakh rana muhammad Ali Ningsheng Chen Waque rana muhammad Umar Almas Sundas Rahman Mahfuzur Key Laboratory of Mountain Hazards and Surface Process Institute of Mountain Hazards and Environment Chinese Academy of Sci-ences Chengdu China University of Chinese Academy of Sciences Beijing China School of Architecture Neijiang Normal University Neijiang China School of Management Northwestern Polytechnical University Xi’an China Key Laboratory for Space Biosciences & Biotechnology School of Life Sciences Northwestern Polytechnical University Xi’an China Department of Civil Engineering International University of Business Agriculture and Technology Dhaka Bangladesh

The main objective of this study is to understand the runoff, sediment yield and water quality of the Upper Indus River Basin of Pakistan. To achieve this goal, specific objectives have been met which include, setup of a hydrological model using Soil and Water Assessment Tool (SWAT) then calibration and validation of the hydrological model using river discharges and in the end investigating the performance of the hydrological model by SWAT. This research will have great impacts on socio-economic conditions of Pakistan because study of upper Indus River basin is imperative to provide data needed for its management, and to warrant that it is sustainable to support the increasing population and conservational flows. A set of programmable mapping components MapWindow Geographic Information System (GIS) was used which is an open source GIS based mapping application. It is SWAT used spatially distributed information on elevation, land use, slope and soil. The program Sequential Uncertainty Fitting ver.2 (SUFI-2) in a combination of uncertainty analysis and calibration of outputs was used in SWAT-CUP. SWAT model used input data, which have climate information to obtain results. The observed climate data of temperature gauges and rain gauge were used as input in the SWAT model;the calibration results for three discharge stations were produced. The initial P-factor value was satisfactory but more iteration to attempt narrow uncertainty band with improving goal function, resulted in small percentage of observed data within uncertainty band. A warm up period of three years (1979-1982) was used for simulation of SWAT model. The model was calibrated for selected three catchments for the period 1982-2000 and validated for period 2001-2010. Results are quite comparable with the observed flows.

关键词： Sediment Transport Runoff GIS SWAT Model Hydrological Modelling Nu-trient Loss

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Location-allocation modeling for emergency evacuation planning with GIS and remote sensing:A case study of Northeast Bangladesh

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Geoscience Frontiers 2021年第3期12卷 169-185页

作者： Mahfuzur Rahman Ningsheng Chen MdMonirul Islam Ashraf Dewan Hamid Reza Pourghasemi rana muhammad AliWashakh Nirdesh Nepal Shufeng Tian Hamid Faiz Mehtab Alam Naveed Ahmed Key Laboratory for Mountain Hazards and Earth Surface Process Institute of Mountain Hazards and Environment(IMHE)Chinese Academy of Sciences(CAS)Chengdu 610041China University of Chinese Academy of Sciences(UCAS) Beijing 100049China Department of Civil Engineering International University of Business Agriculture and Technology(IUBAT)Dhaka 1230Bangladesh School of Earth and Planetary Sciences Curtin UniversityKent StBentleyWA 6102Australia Department of Natural Resources and Environmental Engineering College of AgricultureShiraz UniversityShirazIran School of Architecture Neijiang Normal UniversityNeijiang 641100China Institute of Tibetan Plateau Research Chinese Academy of SciencesBeijing 100101China Global Institute for Interdisciplinary Studies Kathmandu 3084Nepal

This work developed models to identify optimal spatial distribution of emergency evacuation centers(EECs)such as schools,colleges,hospitals,and fire stations to improve flood emergency planning in the Sylhet region of northeastern *** use of location-allocation models(LAMs)for evacuation in regard to flood victims is essential to minimize disaster *** the first step,flood susceptibility maps were developed using machine learning models(MLMs),including:Levenberg-Marquardt back propagation(LM-BP)neural network and decision trees(DT)and multi-criteria decision making(MCDM)*** of the MLMs and MCDM techniques were assessed considering the area under the receiver operating characteristic(AUROC)*** approaches in a geographic information system(GIS)for four well-known LAM problems affecting emergency rescue time are proposed:maximal covering location problem(MCLP),the maximize attendance(MA),p-median problem(PMP),and the location set covering problem(LSCP).The results showed that existing EECs were not optimally distributed,and that some areas were not adequately served by EECs(i.e.,not all demand points could be reached within a 60-min travel time).We concluded that the proposed models can be used to improve planning of the distribution of EECs,and that application of the models could contribute to reducing human casualties,property losses,and improve emergency operation.

关键词： Natural disasters Emergency evacuation centers Flooding Machine learning Multi-criteria decision making Location-allocation model

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Simultaneous hydrogen production with the selective oxidation of benzyl alcohol to benzaldehyde by a noble‐metal‐free photocatalyst VC/CdS nanowires

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Chinese Journal of Catalysis 2022年第4期43卷 1165-1175页

作者： muhammad Tayyab Yujie Liu Shixiong Min rana muhammad Irfan Qiaohong Zhu Liang Zhou Juying Lei Jinlong Zhang Key Laboratory for Advanced Materials Shanghai Engineering Research Center for Multi‐media Environmental Catalysis and Resource UtilizationJoint International Research Laboratory of Precision Chemistry and Molecular EngineeringFeringa Nobel Prize Scientist Joint Research CenterSchool of Chemistry and Molecular EngineeringEast China University of Science&TechnologyShanghai 200237China National Engineering Laboratory for Industrial Wastewater Treatment East China University of Science and TechnologyShanghai 200237China State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process East China University of Science and TechnologyShanghai 200237China School of Chemistry and Chemical Engineering North Minzu UniversityYinchuan 750021NingxiaChina College of Energy Soochow Institute for Energy and Materials Innovations(SIEMIS)Soochow UniversitySuzhou 215006JiangsuChina

In this work we used CdS NWs(nanowires)with vanadium carbide(VC)attached via facile electrostatic self‐assembly and calcination *** results showed that compared to pristine CdS NWs,the photocatalytic activity of CdS NWs loaded with the particular amount of VC was dramatically *** them,the VC/CS‐15 indicated the highest enhancement for simultaneous production of H2 with selective oxidation of benzyl alcohol(BO)into benzaldehyde(BD).The highest hydrogen evolution rate of 20.5 mmol g^(-1)h^(-1)was obtained with more than 99%selectivity for BD production under visible light(λ˃420 nm)irradiation for 2 h,which was almost 661 times higher than the pristine CdS *** enhancement of photocatalytic activity is due to the VC,which provides a favorable attraction for BO by lowering the zeta potential,along with the active site for hydrogen production,and retard the recombination of electron‐hole pairs by increasing the conductivity of the ***,the apparent quantum efficiency(AQE)of VC/CS‐15 for BD and H_(2)production at monochromatic 420 nm is about 7.5%.At the end of the hydrogen evolution test,the selective oxidation with more than 99%selectivity was *** hopes this work will prove its future significance and move scientific community toward a more economical way for achieving the commercialization of H_(2) by photocatalysis.

关键词： Hydrogen production Selective oxidation Benzaldehyde Noble‐metal‐free Visible light

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Salinity Stress in Wheat:Effects,Mechanisms and Management Strategies

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Phyton-International Journal of Experimental Botany 2022年第4期91卷 667-694页

作者： Mahmoud F.Seleiman muhammad Talha Aslam Bushra Ahmed Alhammad muhammadUmair Hassan Rizwan Maqbool muhammad Umer Chattha Imran Khan Harun Ireri Gitari Omer S.Uslu rana Roy Martin Leonardo Battaglia Plant Production Department College of Food and Agriculture SciencesKing Saud UniversityRiyadh11451Saudi Arabia Department of Crop Sciences Faculty of AgricultureMenoufia UniversityShibin El-kom32514Egypt Department of Agronomy University of AgricultureFaisalabad38040Pakistan Biology Department College of Science and Humanity StudiesPrince Sattam Bin Abdulaziz UniversityRiyadh11942Saudi Arabia Research Center on Ecological Sciences Jiangxi Agricultural UniversityNanchang330045China Department of Agricultural Sciences and Technology School of Agriculture and Enterprise DevelopmentKenyatta UniversityNairobi00100Kenya Department of Field Crops Faculty of AgricultureUniversity of Sutcu ImamKahramanmaras46040Turkey Department of Agroforestry&Environmental Science Faculty of AgricultureSylhet Agricultural UniversitySylhet3100Bangladesh Department of Animal Sciences Cornell UniversityIthaca14850USA

Salinity stress is a major threat to global food production and its intensity is continuously increasing because of anthropogenic *** is a staple food and a source of carbohydrates and calories for the majority of people across the ***,wheat productivity is adversely affected by salt stress,which is associated with a reduction in germination,growth,altered reproductive behavior and enzymatic activity,disrupted photosynthesis,hormonal imbalance,oxidative stress,and yield ***,a better understanding of wheat(plant)behavior to salinity stress has essential implications to devise counter and alleviation measures to cope with salt *** approaches including the selection of suitable cultivars,conventional breeding,and molecular techniques can be used for facing salt stress ***,these techniques are tedious,costly,and *** practices are still helpful to improve the wheat performance under salinity *** of arbuscular mycorrhizal fungi,plant growth-promoting rhizobacteria,and exogenous application of phytohormones,seed priming,and nutrient management are important tools to improve wheat performance under salinity *** this paper,we discussed the effect of salinity stress on the wheat crop,possible mechanisms to deal with salinity stress,and management options to improve wheat performance under salinity conditions.

关键词： Breeding techniques oxidative stress photosynthesis phyto-hormones salinity stress wheat

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Application of ferrous sulfate alleviates negative impact of cadmium in rice(Oryza sativa L.)

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BIOCELL 2021年第6期45卷 1631-1649页

作者： JAVARIA AFZAL XIUKANG WANG muhammad HAMZAH SALEEM XUECHENG SUN SHAHID HUSSAIN IMRAN KHAN muhammad SHOAIB rana SHAKEEL AHMED SAMRAH AFZAL AWAN SAJID FIAZ OMAR AZIZ KASHIF ALI KUBAR SHAFAQAT ALI CHENGXIAO HU Key Laboratory of Arable Land Conservation(Middle and Lower Reaches of Yangtze River) Ministry of Agriculture and Rural AffairsHuazhong Agricultural UniversityWuhan430070China Department of Soil Science Sindh Agriculture UniversityTandojam70060Pakistan College of Life Sciences Yan’an UniversityYan’an716000China College of Plant Science and Technology Huazhong Agricultural UniversityWuhan430070China Schools of Materials Science and Engineering Jiangsu UniversityZhenjiang212013China Department of Grassland Science Sichuan Agricultural UniversityChengdu611130China Instituto de Farmacia Facultad de CienciasUniversidad Austral de ChileValdivia5110566Chile Department of Plant Breeding and Genetics The University of HaripurKhyber Pakhtunkhwa22620Pakistan Department of Soil&Environmental Sciences University of Agriculture FaisalabadSub-Campus DepalpurOkaraPakistan Faculty of Agriculture Lasbela University of AgricultureWater and Marine SciencesUthal90150Pakistan Department of Environmental Sciences and Engineering Government College UniversityFaisalabad38000Pakistan Department of Biological Sciences and Technology China Medical UniversityTaichung40402Taiwan

Soil contamination with toxic heavy metals[such as cadmium(Cd)]is becoming a serious global problem due to rapid development of social ***(Fe),being an important element,has been found effective in enhancing plant tolerance against biotic and abiotic *** present study investigated the extent to which different levels of Ferrous sulphate(FeSO_(4))modulated the Cd tolerance of rice(Oryza sativa L.),when maintained in artificially Cd spiked regimes.A pot experiment was conducted under controlled conditions for 146 days,by using natural soil,mixed with different levels of CdCl_(2)[0(no Cd),0.5 and 1 mg/kg]together with the exogenous application of FeSO_(4) at[0(no Fe),1.5 and 3 mg/kg]levels to monitor different growth,gaseous exchange characteristics,oxidative stress,antioxidative responses,minerals accumulation,organic acid exudation patterns of *** results depicted that addition of Cd to the soil significantly(P<0.05)decreased plant growth and biomass,gaseous exchange parameters,mineral uptake by the plants,sugars(soluble,reducing,and non-reducing sugar)and altered the ultrastructure of chloroplasts,plastoglobuli,mitochondria,and many other cellular organelles in Cd-stressed *** compared to those plants which were grown without the addition of Cd in the ***,Cd toxicity boosted the production of reactive oxygen species(ROS)by increasing the contents of malondialdehyde(MDA),which is the indication of oxidative stress in *** and was also manifested by hydrogen peroxide(H_(2)O_(2))contents and electrolyte leakage to the membrane bounded ***,activities of various antioxidative enzymes like superoxidase dismutase(SOD),peroxidase(POD),catalase(CAT)and ascorbate peroxidase(APX)and non-enzymatic antioxidants like phenolics,flavonoid,ascorbic acid,anthocyanin and proline contents increased up to a Cd level of 0.5 mg/kg in the soil but were significantly diminished at the highest Cd level of 1 mg/kg in the soil compar

关键词： Antioxidants Defense mechanism Heavy metals Iron Organic acids exudation

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In Vitro Study on Virulence Potentials of Burkholderia pseudomallei Isolated from Immunocompromised Patients

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Journal of Life Sciences 2012年第10期6卷 1109-1116页

作者： Hadeel Tawfiq Al-Hadithi rana muhammad Abdulnabi Dept. of Biology College of Science University of Basrah Basrah Iraq

Eighty four throat swabs were obtained from Basrah General Hospital inpatients （N = 34）： 17 were suffering from renal failure and the other 17 were diabetics; and from outpatients （N = 50）. Throat swabs were cultured first in the selective media Ashdown＇s broth then subcultured on Ashdown＇s agar to isolate Burkholderia pseudomallei which was recovered from seven cases （8.33%）. Four isolates were from renal failure patients （23.53%）, two from diabetic patients （11.76%） and the seventh isolate was from an outpatient with tonsillitis. All isolates were able to produce capsules, form filament chains, exhibit swarming motility and were arabinose non assimilators （Ara-） indicative of their virulence. Additionally, isolated B. pseudomallei were found to produce protease, lipase, hemolysin, and lecithinase and were able to produce biofilm, the root of many troublesome persistent infections that resist antibiotic treatment. Susceptibility of the seven isolates of B. pseudomallei toward 11 antibiotics was assessed, isolates were found multiply resistant to all antibiotics apart from ciproflaxin. This study confirms for the first time isolation of B. pseudomallei from immunocompromised patients in Basrah city of Iraq and describes their virulence potentials.

关键词： B. pseudomallei virulence potentials biofilm antibiotic susceptibility immunocompromised patients.

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Energy and flux measurements of laser-induced silver plasma ions by using Faraday cup

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Plasma Science and Technology 2021年第8期23卷 188-198页

作者： muhammad Usman Aslam BHATTI Shazia BASHIR Asma HAYAT Khaliq MAHMOOD rana AYUB Mubashir JAVED muhammad Shahzad KHAN Centre for Advanced Studies in Physics(CASP) GC UniversityLahore 54000Pakistan

Silver(Ag)plasma has been generated by employing Nd:YAG laser(532 nm,6 ns)laser *** energy and flux of ions have been evaluated by using Faraday cup(FC)using time of flight(TOF)*** dual peak signals of fast and slow Ag plasma ions have been *** energy and flux of fast and slow ions tend to increase with increasing irradiance from 7 GW cm-2 to 17.9 GW cm-2 at all distances of FC from the target *** a decreasing trend of energies and flux of ions has been observed with increasing distance of FC from the *** maximum value of flux of the fast component is21.2×10^(10) cm^(-2),whereas for slow ions the maximum energy and flux values are 8.8 keV,8.2×10^(10) cm^(-2) *** the analysis of plume expansion dynamics,the angular distribution of ion flux measurement has also been *** overall analysis of both spatial and angular distributions of Ag ions revealed that the maximum flux of Ag plasma ions has been observed at an optimal angle of~15°.In order to confirm the ion acceleration by ambipolar field,the self-generated electric field(SGEF)measurements have also been performed by electric probe;these SGEF measurements tend to increase by increasing laser *** maximum value of 232 V m^(-1) has been obtained at a maximum laser irradiance of 17.9 GW cm^(-2).

关键词： laser ablation laser-induced plasma ions Faraday cup time of flight measurements self-generated electric field angular distribution

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A Longitudinal Survey for Genome-based Identification of SARS-CoV-2 in Sewage Water in Selected Lockdown Areas of Lahore City, Pakistan: A Potential Approach for Future Smart Lockdown Strategy

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Biomedical and Environmental Sciences 2021年第9期34卷 729-733页

作者： Tahir Yaqub muhammad Nawaz muhammad Z.Shabbir muhammad A.Ali Imran Altaf Sohail Raza muhammad A.B.Shabbir muhammad A.Ashraf Syed Z.Aziz Sohai l Q.Cheema muhammad B.Shah Saira Rafique Sohail Hassan Nageen Sardar Adnan Mehmood muhammad W.Aziz Sehar Fazal Nadir Hussain muhammad T.Khan muhammad M.Atique Ali Asif muhammad Anwar Nabeel A.Awan muhammad U.Younis muhammad A.Bhattee Zarfishan Tahir Nadia Mukhtar Huda Sarwar Maaz S.rana Omair Farooq Institute of Microbiology University of Veterinary and Animal SciencesLahorePakistan Water and Sanitation Agency LahorePunjabPakistan Specialized Healthcare&Medical Education Department PunjabPakistan Primary and Secondary Healthcare Department PunjabPakistan Institute of Public Health LahorePakistan Farooq Hospital LahorePakistan

In 2019,the newly emerged SARS-CoV-2 virus caused pneumonia-like *** disease rapidly spread globally,leading to a worldwide outbreak referred to as the COVID-19 pandemic.

关键词： globally Strategy Smart

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基于边缘投影轮廓法的图像边缘识别算法在三维重建中的应用

基于边缘投影轮廓法的图像边缘识别算法在三维重建中的应用

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作者： Awais rana muhammad 渤海大学

学位级别：硕士

在投影条纹法的应用中,往往需要大量的后处理工作。因为相机视场不可能恰好等于待测物的面积,在测量过程中也伴随着对不必要信息的测量,增加了需要处理的数据量和噪声来源,故需要在后处理过程中再去除这些噪声。而现有的图像边缘识别算... 详细信息

在投影条纹法的应用中,往往需要大量的后处理工作。因为相机视场不可能恰好等于待测物的面积,在测量过程中也伴随着对不必要信息的测量,增加了需要处理的数据量和噪声来源,故需要在后处理过程中再去除这些噪声。而现有的图像边缘识别算法可以良好的克服上述问题,将有效区域,即待测物边缘,自动智能地识别出来,从而可以分割出图像的有效区域,仅对这一块区域处理。因此,将图像边缘识别算法和投影条纹法结合应用可以有效地减少待处理数据量从而提升后处理效率,并且可以有效降低由不必要信息引入的噪音显著提升图像数据信噪比和形貌重建的质量。本文通过介绍非接触光学测量方法入手,逐步介绍了投影条纹法的实现步骤及误差控制方案,之后进一步介绍了数种图像边缘识别算子及其处理效果。在此基础上引出本文提出的方法:通过将图像边缘识别算子应用于图像分割可以将投影条纹法的后处理步骤进行简化,即可以利用图像分割技术将边缘外背景噪声自动过滤,取代了繁琐的手动滤波,且能获得信噪比更高的图像数据。文章末尾利用3DMAX和Matlab软件进行了仿真实验,对比手动滤波结果可以清晰看出本文方法的优越性。

关键词：投影条纹边缘识别三维重建滤波器

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