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Real time endoscopic ultrasound elastography and strain ratio in the diagnosis of solid pancreatic lesions

World Journal of Gastroenterology 2017年第32期23卷 5962-5968页

作者： Hussein Okasha Shaimaa elkholy ramy el-sayed Mohamed-Naguib Wifi Mohamed el-Nady Walid el-Nabawi Waleed A el-Dayem Mohamed I Radwan Ali Farag Yahya el-sherif Emad Al-Gemeie Ahmed Salman Mohamed el-Sherbiny Ahmed el-Mazny Reem E Mahdy Internal Medicine Department Cairo University Department of Tropical Medicine Zagazig University Internal Medicine Department Beni Suef University Tropical Medicine Department El Manial Specialized Hospital Pathology Department National Cancer InstituteCairo University Internal Medicine Department Assiut University

AIM To evaluate the accuracy of the elastography score combined to the strain ratio in the diagnosis of solid pancreatic lesions(SPL). METHODS A total of 172 patients with SPL identified by endoscopic ultrasound were enrolled in the study to evaluate the efficacy of elastography and strain ratio in differentiating malignant from benign lesions. The semi quantitative score of elastography was represented by the strain ratio method. Two areas were selected, area(A) representing the region of interest and area(B) representing the normal area. Area(B) was then divided by area(A). Sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV), and accuracy were calculated by comparing diagnoses made by elastography, strain ratio and final *** SPL were shown to be benign in 49 patients and malignant in 123 patients. elastography alone had a sensitivity of 99%, a specificity of 63%, and an accuracy of 88%, a PPV of 87% and an NPV of 96%. The best cut-off level of strain ratio to obtain the maximal area under the curve was 7.8 with a sensitivity of 92%, specificity of 77%, PPV of 91%, NPV of 80% and an accuracy of 88%. Another estimated cut off strain ratio level of 3.8 had a higher sensitivity of 99% and NPV of 96%, but with less specificity, PPV and accuracy 53%, 84% and 86%, respectively. Adding both elastography to strain ratio resulted in a sensitivity of 98%, specificity of 77%, PPV of 91%, NPV of 95% and accuracy of 92% for the diagnosis of SPL. CONCLUSION Combining elastography to strain ratio increases the accuracy of the differentiation of benign from malignant SPL.

关键词： Endoscopic Ultrasound elastography Strain Ratio Real Time Pancreatic lesions

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Effects of Moringa oleifera aqueous extract on the growth performance,blood characteristics,and histological features of gills and livers in Nile tilapia

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Aquaculture and Fisheries 2024年第1期9卷 85-92页

作者： Mahamoud A.Emam ramy M.Shourbela Waleed N.el-Hawarry Seham Y.Abo-Kora Fatma Abdel-Monem Gad Ashraf M.Abd el-latif Mahmoud A.O.Dawood Histology Department Faculty of Veterinary MedicineBenha UniversityBenha13511Egypt Department of Animal Husbandry and Animal Wealth Development Faculty of Veterinary MedicineAlexandria UniversityAlexandria22758Egypt Pharmacology Department Faculty of Veterinary MedicineBenha UniversityBenha13511Egypt Clinical Pathology Department Faculty of Veterinary MedicineBenha UniversityBenha13511Egypt Department of Aquatic Animal Diseases and Management Faculty of Veterinary MedicineBenha UniversityBenha13511Egypt Animal Production Department Faculty of AgricultureKafrelsheikh UniversityKafr El-Sheikh33511Egypt The Center for Applied Research on the Environment and Sustainability The American University in CairoCairo11835Egypt

Moringa oleifera is well known as a highly nutritious plant and a water purifier in fish *** fish has many impressive qualities making them very suitable for ***,this study aimed to evaluate the effect of supplementation of Moringa oleifera aqueous extract(MOAE)at varying concentrations(0,100,200,and 400 mg/kg diet for 90 days)on growth performance,hematological,and some biochemical parameters of Nile ***,histological changes and immunohistochemical expression of caspase 3 in gills and livers were *** enhancements(Pells,hemoglobin,packed cell volume,white blood cells,and total serum protein were observed in fish fed 200 mg MOAE/kg diet compared with other ***,a significant reduction(Pells indicating severe apoptotic ***,a dietary MOAE at 200 mg/kg diet is recommended to improve the growth performance,hematological parameters,liver and kidney functions in Nile ***,caution must be considered when using MOAE at a concentration over 200 mg/kg diet.

关键词： Growth performance Liver Gills Moringa oleifera Nile tilapia

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Gastrointestinal and hepatic diseases during the COVID-19 pandemic:Manifestations,mechanism and management

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World Journal of Gastroenterology 2021年第28期27卷 4504-4535页

作者： Dina Zakaria Mohamed Mai el-sayed Ghoneim Sally el-sayed Abu-Risha ramy Ahmed Abdelsalam Mohamed Abdelhalem Farag Department of Pharmacology and Toxicology Faculty of PharmacyTanta UniversityTanta 31511Egypt Department of Pharmacology and Toxicology Faculty of PharmacyUniversity of Sadat CityMenoufia 32632Egypt Department of Pathology Faculty of MedicineMansoura UniversityMansoura 35511Egypt Department of Pediatrics Nebru General HospitalNebru 35511Egypt

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is considered the causative pathogen of coronavirus disease 2019(COVID-19)and has become an international danger to human *** respiratory transmission and symptoms are still the essential manifestations of COVID-19,the digestive system could be an unconventional or supplementary route for COVID-19 to be transmitted and manifested,most likely due to the presence of angiotensin-converting enzyme 2(ACE2)in the gastrointestinal *** addition,SARS-CoV-2 can trigger hepatic injury via direct binding to the ACE2 receptor in cholangiocytes,antibodydependent enhancement of infection,systemic inflammatory response syndrome,inflammatory cytokine storms,ischemia/reperfusion injury,and adverse events of treatment *** symptoms,including anorexia,nausea,vomiting,and diarrhea,which are unusual in patients with COVID-19,and some digestive signs may occur without other respiratory ***,SARS-CoV-2 can be found in infected patients’stool,demonstrating the likelihood of transmission through the fecal-oral *** addition,liver function should be monitored during COVID-19,particularly in more severe *** review summarizes the evidence for extra-pulmonary manifestations,mechanisms,and management of COVID-19,particularly those related to the gastrointestinal tract and liver.

关键词： COVID-19 Angiotensin-converting enzyme 2 Gastrointestinal Inflammatory bowel disease Liver Management

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Denoising different types of acoustic partial discharge signals using power spectral subtraction

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High Voltage 2018年第1期3卷 44-50页

作者： ramy Hussein Khaled Bashir Shaban Ayman H.el-Hag Department of electrical and Computer Engineering University of British ColumbiaVancouverBCCanada Department of Computer Science and Engineering Qatar UniversityDohaQatar Department of electrical Engineering American University of SharjahSharjahUAE

Measuring acoustic emission(AE)of partial discharge(PD)phenomena can be adopted to estimate the condition of power ***,the environmental noise encountered with AE of PD measurements negatively affects the accuracy of PD localisation and ***,efficient signal denoising techniques are required for noise suppression and hence,better detection *** study deals with white noise and it is a continuation of a previously published work that deals with random *** published work addresses the random noise suppression using a method named,power spectral subtraction denoising(PSSD).This study applies PSSD to the PD signals contaminated with white noise and uses a novel scheme of noise power spectrum density *** types of AE signals are examined including signals produced by corona,surface,parallel,and void *** and real data demonstrate the superiority of the proposed method over the wavelet shrinkage denoising method as it can more effectively eliminate white noise and preserve signals of low signal-to-noise ratio.

关键词： power noise spectral

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Effect of heat input and filler metals on weld strength of gas tungsten arc welding of AISI 316 weldments

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China Welding 2020年第1期29卷 8-16页

作者： Essam Ahmed ramy Ahmed A el-Nikhaily A R S Essa Metallurgical and Materials Engineering Department Faculty of Petroleum and Mining EngineeringSuez University43721 Egypt Mechanical Department Faculty of Industrial EducationSuez University43721 Egypt Mechanical Engineering Department Egyptian Academy for Engineering&Advanced TechnologyAffiliated to Ministry of Military ProductionCairo 3056Egypt

The present work investigates the effect of filler metals and heat input on weld bead geometry and mechanical properties of alloy316 welded by using ***309 L,ER316 L and ERNi Cr Mo-3 filler metals,are applied to study their effect on the *** defects are examined using radiographic *** mechanical properties of welds are evaluated through uniaxial testing,hardness measuring,and bending *** mechanical properties and cooling rate decrease with increasing heat *** strength,yield stress and percentage elongation of weldments using three fillers are *** results are obtained using ERNi Cr ***,weld nugget area,cooling time and solidification time increases with increasing heat ***,applying bending test on weld samples,cracks,tearing and surface defects are not observed.

关键词： TIG welding filler metals nugget area stainless steel cooling rate

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Assessment of lnc RNA GAS5, lnc RNA HEIH, lnc RNA BISPR and its m RNA BST2 as serum innovative non-invasive biomarkers: Recent insights into Egyptian patients with hepatitis C virus type 4

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World Journal of Gastroenterology 2020年第2期26卷 168-183页

作者： Nourhan M el Samaloty Marwa I Shabayek ramy S Ghait Shohda A el-Maraghy Sherine M Rizk Maha M el-Sawalhi Biochemistry Section PharmacologyToxicology and Biochemistry DepartmentFaculty of Pharmaceutical Sciences and Pharmaceutical IndustriesFuture UniversityCairo 11795Egypt Internal Medicine Gastroenterology and Hepatology DepartmentFaculty of MedicineAin Shams UniversityCairo 11566Egypt Biochemistry Department Faculty of PharmacyCairo UniversityCairo 11562Egypt

BACKGROUND Hepatitis C virus(HCV)infection and its consequent complications are undeniably a public health burden worldwide,particularly in *** evidence suggests that many lncRNAs have relevant roles in viral infections and antiviral *** To investigate the expression profiles of circulating lncRNAGAS5,lncRNAHEIH,lncRNABISPR and mRNABST2 in naïve,treated and relapsed HCV Egyptian patients,to elucidate relation to HCV infection and their efficacy as innovative biomarkers for the diagnosis and prognosis of HCV *** One hundred and thirty HCV-infected Egyptian patients and 20 healthy controls were included in this *** lncRNAs and mRNABST2 were measured using quantitative real-time polymerase chain reaction(qRT-PCR).RESULTS Our results indicated that serum lncRNAGAS5 and LncRNABISPR were upregulated,whereas mRNA BST2 and LncRNA HEIH were downregulated in naïve *** contrast,HCV patients treated with sofosbuvir and simeprevir;with sofosbuvir and daclatasvir;or with sofosbuvir,daclatasvir and ribavirin exhibited lower levels of lncRNAGAS5 and lncRNABISPR with higher mRNABST2 compared to naïve ***,patients relapsed from sofosbuvir and simeprevir showed higher levels of these lncRNAs with lower mRNABST2 compared to treated ***5 and lncRNABISPR were positively correlated with viral load and ALT at Pely correlated with viral load at Pelation between lncRNA HEIH and AFP was observed at P<*** Differential expression of these RNAs suggests their involvement in HCV pathogenesis or antiviral response and highlights their promising roles in diagnosis and prognosis of HCV.

关键词： lncRNA GAS5 lncRNA BISPR mRNA BST2 lncRNA HEIH Hepatitis C Biomarkers

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Cystic pancreatic lesions,the endless dilemma

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World Journal of Gastroenterology 2021年第21期27卷 2664-2680页

作者： Hussein Hassan Okasha Abeer Awad Ahmed el-meligui Reem Ezzat Ashraf Aboubakr Sameh Abouelenin ramy el-Husseiny Ahmed Alzamzamy Department of Internal Medicine and Gastroenterology Hepatology UnitKasr Al-Aini HospitalsCairo UniversityCairo 11562Egypt Department of Internal Medicine and Gastroenterology Hepatology UnitAssuit UniversityAssuit 71515Egypt Department of Gastroenterology and Hepatology Maadi Armed Forces Medical ComplexMilitary Medical AcademyCairo 11441Egypt Department of Gastroenterology and Hepatology Military Medical AcademyCairo 11441Egypt Department of Hepatology and Tropical Medicine National Hepatology and Tropical Medicine Research Institute(NHTMRI)Cairo 11441Egypt

Cystic pancreatic lesions involve a wide variety of pathological entities that include neoplastic and non-neoplastic *** proper diagnosis,differentiation,and staging of these cystic lesions are considered a crucial issue in planning further *** are great challenges for their diagnostic *** our time,new emerging methods for this diagnosis have been *** ultrasonography-guided fine-needle aspiration cytology with chemical and molecular analysis of cyst fluid and EUS-guided fine needlebased confocal laser endomicroscopy,through the needle microforceps biopsy,and single-operator cho-langioscopy/pancreatoscopy are promising methods that have been used in the diagnosis of cystic pancreatic *** we discuss the diagnosis of cystic pancreatic lesions and the benefits of various diagnostic models.

关键词： Pancreatic cystic lesion Endoscopic diagnosis Endoscopic ultrasonography Cyst fluid markers Endoscopic ultrasonography-guided fine needle-based confocal laser endomicroscopy Through the needle microforceps biopsy Single operator cholangioscopy/pancreatoscopy

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Ultrasonic Rangefinder Spikes Rejection Using Discrete Wavelet Transform: Application to UAV

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Journal of Sensor Technology 2015年第2期5卷 45-53页

作者： Ayman el-Badawy ramy Rashad Mechanical Engineering Department Al-Azhar University and German University Cairo Egypt Mechatronics Department German University Cairo Egypt

This paper presents a spikes removing methodology for ultrasonic rangefinders with an application to a quadrotor unmanned aerial vehicle. Ultrasonic sensors suffer from spikes in distance measurements due to specular reflectance and acoustic noise. Removing these spikes is necessary for improving the hovering performance of the quadrotor. The spikes removing algorithm is based on the discrete wavelet transform. The algorithm is implemented in simulation to study the effect of the altitude measurement spikes on the control performance of the quadrotor with and without the algorithm. The algorithm is also implemented digitally on ultrasonic measurements from a real flight. Results show that the method is capable of rejecting the spikes in the measurements efficiently leaving the altitude control signal unaffected.

关键词： Discrete Wavelet Transform Quadrotor Ultrasonic Spikes Rejection

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STW 5 is effective against nonsteroidal anti-inflammatory drugs induced gastro-duodenal lesions in rats

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World Journal of Gastroenterology 2019年第39期25卷 5926-5935页

作者： Mohamed T Khayyal Walaa Wadie Enas A Abd el-Haleim Kawkab A Ahmed Olaf Kelber ramy M Ammar Heba Abdel-Aziz Department of Pharmacology Faculty of PharmacyCairo UniversityCairo 11562Egypt Department of Pathology Faculty of Veterinary MedicineCairo UniversityCairo 12211Egypt Steigerwald Arzneimittelwerk GmbH Bayer Consumer HealthDarmstadt 64295Germany Department of Pharmacology Faculty of PharmacyKafrelsheikh UniversityKafrelsheikh 33511Egypt

BACKGROUND Proton pump inhibitors are often used to prevent gastro-intestinal lesions induced by nonsteroidal anti-inflammatory ***,they are not always effective against both gastric and duodenal lesions and their use is not devoid of side *** To explore the mechanisms mediating the clinical efficacy of STW 5 in gastroduodenal lesions induced by nonsteroidal anti-inflammatory drugs(NSAIDs),exemplified here by diclofenac,in a comparison to *** Gastro-duodenal lesions were induced in rats by oral administration of diclofenac(5 mg/kg)for 6 successive *** group was given concurrently STW 5(5 mL/kg)while another was given omeprazole(20 mg/kg).A day later,animals were sacrificed,stomach and duodenum excised and divided into 2 segments:One for histological examination and one for measuring inflammatory mediators(tumor necrosis factorα,interleukins-1βand 10),oxidative stress enzyme(heme oxygenase-1)and apoptosis regulator(B-cell lymphoma 2).RESULTS Diclofenac caused overt histological damage in both tissues,associated with parallel changes in all parameters *** 5 and omeprazole effectively prevented these changes,but STW 5 superseded omeprazole in protecting against histological damage,particularly in the *** The findings support the therapeutic usefulness of STW 5 and its superiority over omeprazole as adjuvant therapy to NSAIDs to protect against their possible gastro-duodenal side effects.

关键词： Diclofenac STW 5 Omeprazole Gastro-intestinal lesions Inflammation

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La^3+ doped LiCo0.25Zn0.25Fe2O4 spinel ferrite nanocrystals:Insights on structural,optical and magnetic properties

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Journal of Rare Earths 2021年第1期39卷 75-82,I0003页

作者： M.I.A.Abdel Maksoud Ahmed el-Ghandour A.H.Ashour M.M.Atta Soraya Abdelhaleem Ahmed H.el-Hanbaly ramy Amer Fahim Said M.Kassem M.S.Shalaby A.S.Awed Materials Science Lab. Radiation Physics DepartmentNational Center for Radiation Research and Technology(NCRRT)Atomic Energy AuthorityCairoEgypt Center Photonics and Smart Materials(CPSM) Zewail City of Science and TechnologyOctober Gardens6th of October CityGizaEgypt Polymers Physics Lab. Radiation Physics DepartmentNational Center for Radiation Research and Technology(NCRRT)Atomic Energy AuthorityCairoEgypt Egyptian Nuclear and Radiological Regulatory Authority CairoEgypt Radiation Protection and Dosimetry Department National Center for Radiation Research and Technology(NCRRT)Atomic Energy AuthorityCairoEgypt Magnetic and Thermal Lab Solid State&Accelerators DepartmentNational Center for Radiation Research and TechnologyAtomic Energy AuthorityNasr CityCairoEgypt Higher Institute for Engineering and Technology ManzalaDakahliaEgypt

This paper addresses the manipulation of structural,morphology,optical and magnetic properties of LiCo0.25Zn0.25Fe2 O4 ferrite via incorporation of different proportions of La^3+at the expense of iron ions using a sol-gel *** samples were characterized using the X-ray diffraction technique(XRD),Fourier transform infrared(FT-IR)spectroscopy,the energy dispersive X-ray spectra(EDX),inductively coupled plasma optical emission spectroscopy(ICP-OES),high resolution scanning electron microscopy(SEM),Brunauer-Emmett-Teller(BET)surface area analysis,ultraviolet-diffuse reflectance spectroscopy(UV-DRS),and vibrating sample magnetometer(VSM)*** Rietveld refinements of the samples indicate that at higher concentrations of La^3+,nanostructures with dual phase,*** spinel and orthorhombic LaFeO3 perovskite with space group(Pbnm)*** studies show that the energy band gap(Eg)of the bare LiCo0.25Zn0.25Fe2 O4 ferrite sample(2.18 eV)reaches up to 2.47 eV at x=0.06 and above this concentration,it drops sharply to 2.00 *** the saturation magnetization and the coercivity of LiCo0.25Zn0.25LaxFe2-xO4 are lower than that of LiCo0.25Zn0.25Fe2 O4 ***,the superparamagnetic nature and low values of saturation magnetization and coercivity of LiCo0.25Zn0.25LaxFe2-xO4 NPs are suitable to be applied in transformers core.

关键词： Li-Co-Zn ferrite Superparamagnetic nature Optical properties Magnetic behavior Transformers core Rare earths

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