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Renal function assessment in atrial fibrillation:Usefulness of chronic kidney disease epidemiology collaboration vs reexpressed 4 variable modification of diet in renal disease

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World Journal of Cardiology 2015年第10期7卷 685-694页

作者： rami riziq-yousef abumuaileq Emad Abu-Assi Andrea López-López Sergio Raposeiras-Roubin Moisés Rodríguez-Manero Luis Martínez-Sande Francisco Javier García-Seara Xesus Alberte Fernandez-López Jose Ramón González-Juanatey Cardiology Department University Clinical Hospital of Santiago de Compostela

AIM: To compare the performance of the re-expressed Modification of Diet in Renal Disease equation vs the new Chronic Kidney Disease Epidemiology Collaboration equation in patients with non-valvular atrial ***: We studied 911 consecutive patients with non-valvular atrial fibrillation on vitamin-K antagonist. The performance of the re-expressed Modification of Diet in Renal Disease equation vs the new Chronic Kidney Disease Epidemiology Collaboration equation in patients with non-valvular atrial fibrillation with respect to either a composite endpoint of major bleeding, thromboembolic events and all-cause mortality or each individual component of the composite endpoint was assessed using continuous and categorical ≥ 60, 59-30, and < 30 m L/min per 1.73 m2 estimated glomerular filtration ***: During 10 ± 3 mo, the composite endpoint occurred in 98(10.8%) patients: 30 patients developed major bleeding, 18 had thromboembolic events, and 60 died. The new equation provided lower prevalence of renal dysfunction < 60 m L/min per 1.73 m2(32.9%),compared with the re-expressed equation(34.1%). Estimated glomerular filtration rate from both equations was independent predictor of composite endpoint(HR = 0.98 and 0.97 for the re-expressed and the new equation, respectively; P < 0.0001) and all-cause mortality(HR = 0.98 for both equations, P < 0.01). Strong association with thromboembolic events was observed only when estimated glomerular filtration rate was < 30 m L/min per 1.73 m2: HR is 5.1 for the re-expressed equation, and HR = 5.0 for the new equation. No significant association with major bleeding was observed for both ***: The new equation reduced the prevalence of renal dysfunction. Both equations performed similarly in predicting major adverse outcomes.

关键词： Atrial fibrillation Anticoagulants Follow-up studies Kidney Prognosis

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Enhancing the Decomposition of Paper Cups Using Galleria Mellonella and Eisenia Fetida

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Journal of Renewable Materials 2024年第2期12卷 349-367页

作者： Shadi Moqbel Habib Al-Ghoul Abd Al-Majeed Al-Ghzawi rami Mukbel Civil Engineering Department The University of JordanAmman11942Jordan Department of Chemistry Technical University of MunichMunichGermany Plant Production Jordan University of Science and TechnologyIrbid22110Jordan Basic Medical Veterinary Sciences Jordan University of Science and TechnologyIrbid22110Jordan

The composition of paper cups creates a challenge for the recycling industry,as the paperboard–plastic film composite is hard to ***,paper cups are sent to landfills or waste *** study explores the combined use of red worms(Eisenia fetida)and Greater wax moth(Galleria mellonella)in the biodegradation of paper *** study investigates the conditions and combinations that promote using Eisenia fetida and Galleria mellonella for degrading paper *** study considered the influence of environmental temperature,the presence of food waste,varying the number of Eisenia fetida worms,and the presence of a Galleria mellonella growth-slowing agent on the degradation *** achieve the study objectives,the study followed a quantitative *** study monitored the degradation of paper cup cuts that were placed in jars containing different combinations of Eisenia fetida worms,Galleria mellonella larvae,food waste,bedding material,and Galleria mellonella growth-slowing *** study found that the best operating temperature is *** study found that using food waste improves the performance of Eisenia fetida worms and Galleria mellonella larvae *** study found that adding a Galleria mellonella growth-slowing agent slightly enhances the degradation of the paper ***,a numerical model was obtained to simulate the paper cup degradation efficiency.

关键词： Paper cups resource recovery recycling circular economy Galleria mellonella Eisenia fetida

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Non-Uniform Pion Tetrahedron Aether and Electron Tetrahedron Model

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Journal of High Energy Physics, Gravitation and Cosmology 2024年第2期10卷 810-824页

作者： rami Rom Independent Researcher Zikhron-Yaakov Israel

We propose that the QCD vacuum pion tetrahedron condensate density vary in space and drops to extremely low values in the Kennan, Barger and Cowie (KBC) void in analogy to earth’s atmospheric density drop with elevation from earth. We propose a formula for the gravitation acceleration based on the non-uniform pion tetrahedron condensate. Gravity may be due to the underlying microscopic attraction between quarks and antiquarks, which are part of the vacuum pion tetrahedron condensate. We propose an electron tetrahedron model, where electrons are comprised of tetraquark tetrahedrons, and . The quarks determine the negative electron charge and the or quarks determine the electron two spin states. The electron tetrahedron may perform a high frequency quark exchange reactions with the pion tetrahedron condensate by tunneling through the condensation gap creating a delocalized electron cloud with a fixed spin. The pion tetrahedron may act as a QCD glue bonding electron pairs in atoms and molecules and protons to neutrons in the nuclei. Conservation of valence quarks and antiquarks is proposed.

关键词： Standard Model (SM) QCD Vacuum Condensate Electric Dipole Moment (EDM) KBC Void Antimatter MOND Theory Aether

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The Pionic Deuterium and the Pion Tetrahedron Vacuum Polarization

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Journal of High Energy Physics, Gravitation and Cosmology 2024年第1期10卷 329-345页

作者： rami Rom Zikhron-Ya’akov Israel

A double-well potential model is proposed for the pionic deuterium that enables to calculate the energy split, the potential barrier height and estimate the pion tetrahedron edge length. We propose that pion tetrahedrons, πTd = ud~dũ, play a central role in the Yukawa interaction by enabling quark exchange reactions between protons and neutrons by tunneling through a potential barrier. A vacuum polarization Feynman diagram is proposed for the πTd having chains of fermion loops for the two valence quarks and anti-quarks connected by gluons. With a higher order vacuum polarization diagram, the d and u quark loops are interleaved and the chiral symmetry is broken dynamically. The proposed πTd vacuum polarization integral does not diverge in both the IR and UV limits and vanishes in the limit of an infinite pion tetrahedron condensate. We propose a new Delbruck scattering Feynman diagram that includes d and u quark and anti-quark interleaved loops. We further propose that conversion of gravitons to photons may occur via quark and anti-quark loops that describe the pion tetrahedrons dynamics in the vacuum and may also transfer gravitational waves.

关键词： Pionic Deuterium (πD) Yukawa Interaction QCD Vacuum Double-Well Potential Chiral Perturbation Theory Vacuum Polarization Gravitational Waves

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The Dependence between Solar Flare Emergence and the Average Background Solar X-Ray Flux Emission

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International Journal of Astronomy and Astrophysics 2024年第3期14卷 149-161页

作者： Yael Peleg rami Babayew Itzhak Orion Nuclear Engineering Unit Ben Gurion University of the Negev Beer Sheva Israel

Solar flares, sudden bursts of intense electromagnetic radiation from the Sun, can significantly disrupt technological infrastructure, including communication and navigation satellites. To mitigate these risks, accurate forecasting of solar activity is crucial. This study investigates the potential of the Sun’s background X-ray flux as a tool for predicting solar flares. We analyzed data collected by solar telescopes and satellites between the years 2013 and 2023, focusing on the duration, frequency, and intensity of solar flares. We compared these characteristics with the background X-ray flux at the time of each flare event. Our analysis employed statistical methods to identify potential correlations between these solar phenomena. The key finding of this study reveals a significant positive correlation between solar flare activity and the Sun’s background X-ray flux. This suggests that these phenomena are interconnected within the framework of overall solar activity. We observed a clear trend: periods with increased occurrences of solar flares coincided with elevated background flux levels. This finding has the potential to improve solar activity forecasting. By monitoring background flux variations, we may be able to develop a more effective early warning system for potentially disruptive solar flares. This research contributes to a deeper understanding of the complex relationship between solar flares and the Sun’s overall radiative output. These findings indicate that lower-resolution X-ray sensors can be a valuable tool for identifying periods of increased solar activity by allowing us to monitor background flux variations. A more affordable approach to solar activity monitoring is advised.

关键词： Space Weather Solar Flare Solar Activity Sunspots Solar Cycle

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Application of near-infrared spectroscopy for fast germplasm analysis and classification in multi-environment using intact-seed peanut(Arachis hypogaea L.)

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Oil Crop Science 2024年第2期9卷 132-141页

作者： Fentanesh Chekole Kassie Gilles Chaix Hermine Bille Ngalle Maguette Seye Coura Fall Hodo-Abalo Tossim Aissatou Sambou Olivier Gibert Fabrice Davrieux Joseph Martin Bell Jean-Francois rami Daniel Fonceka Joel Romaric Nguepjop Department of Plant Biology and Physiology Faculty of SciencesUniversity of Yaounde IYaoundeP.O.Box 337Cameroon Department of Plant Science College of AgricultureWolaita Sodo UniversitySodoP.O.Box 138Ethiopia CIRAD UMR AGAP InstitutMontpellierFrance AGAP Institut Univ MontpellierCIRADINRAEInstitut AgroMontpellierFrance ChemHouse Research Group MontpellierFrance Centre D’Etudes Regional Pour L’Amelioration de L’Adaptation a La Secheresse(CERAAS/ISRA) Route de KhomboleThiesBP 3320Senegal Dispositif de Recherche et de Formation en Partenariat Innovation et Amelioration Varietale en Afrique de L’Ouest(IAVAO)CERAASRoute de KhomboleThiesBP 3320Senegal CIRAD UMR QUALISUDSaint PierreFrance

Peanut is a worldwide oilseed crop and the need to assess germplasm in a non-destructive manner is important for seed nutritional *** this study,Near Infrared Spectroscopy(NIRS)was applied to rapidly assess germplasm variability from whole seed of 699 samples,field-collected and assembled in four genetic and environmentbased sets:one set of 300 varieties of a core-collection and three sets of 133 genotypes of an interspecific population,evaluated in three environments in a large spatial scale of two countries,Mbalmayo and Bafia in Cameroon and Nioro in Senegal,under rainfed *** elemental spectra were gathered on six subsets of seeds of each sample,after three rotation scans,with a spectral resolution of 16 cm-1over the spectral range of867 nm to 2530 *** were then processed by principal component analysis(PCA)coupled with Partial least squares-discriminant analysis(PLS-DA).As results,a huge variability was found between varieties and genotypes for all NIR wavelength within and between *** magnitude of genetic variation was particularly observed at 11 relevant wavelengths such as 1723 nm,usually related to oil content and fatty acid *** yielded the most chemical attributes in three significant PCs(i.e.,eigenvalues>10),which together captured 93%of the total variation,revealing genetic and environment structure of varieties and genotypes into four clusters,corresponding to the four samples *** pattern of genetic variability of the interspecific population covers,remarkably half of spectrum of the core-collection,turning out to be the ***,a PLS-DA model was developed and a strong accuracy of 99.6%was achieved for the four sets,aiming to classify each seed sample according to environment *** confusion matrix achieved for the two sets of Bafia and Nioro showed 100%of instances classified correctly with 100%at both sensitivity and specificity,confirming that their seed quality was different f

关键词： Groundnut Oilseed Near infrared spectroscopy Germplasm analysis Environment Nutritional Breeding

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基于嵌入式网格的裂缝性致密油储层压裂生产一体化数值模拟方法

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计算物理 2024年

作者：徐世乾郭建春 Younis M.rami 卢聪 Texas A&M University， Harold Vance Department of Petroleum Engineering， College Station 西南石油大学油气藏地质及开发工程国家重点实验室

有效的一体化模拟裂缝性致密油储层压裂生产过程是评价压裂设计的关键之一。为此，基于嵌入式网格的基质裂缝全域空间流固耦合数值模拟方法，进一步考虑天然裂缝影响下裂缝动态扩展、低速非线性渗流、基质与裂缝应力敏感，实现了裂缝性... 详细信息

有效的一体化模拟裂缝性致密油储层压裂生产过程是评价压裂设计的关键之一。为此，基于嵌入式网格的基质裂缝全域空间流固耦合数值模拟方法，进一步考虑天然裂缝影响下裂缝动态扩展、低速非线性渗流、基质与裂缝应力敏感，实现了裂缝性致密油储层压裂生产一体化多机理模拟。进而分析了天然裂缝、非线性渗流对裂缝扩展及生产动态的一体化影响规律。研究结果表明：模型可以在生产过程中任意时刻模拟压裂，为重复压裂、加密井的设计分析提供了有效工具。当基质岩石的抗拉强度由10.2 MPa降到2.3 MPa时，破碎带逐渐增大，滤失作用增加，导致主裂缝长度降低8%-9%，但可以增加累产油量17.5%至61.1%，影响作用显著且主要影响早期的日产油量。与启动压力梯度模型相比，低速非线性渗流可以更好地预测致密油生产动态。该方法为裂缝性致密油储层压裂生产一体化的动态预测、规律分析、工艺优化提供了高效工具。

关键词：致密油裂缝性储层流固耦合压裂生产一体化嵌入式网格

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Comprehensive Assessment of Anxiolytic Properties in 4-HPAA Derivatives: Bridging in Vivo Validation and Molecular Docking Analyses

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Open Journal of Medicinal Chemistry 2024年第3期14卷 29-44页

作者： Kawthar Alhussieni rami Ayoub Jamal Jilani Qais Jarrar Othman Alhussinei Vetriselvan Subramaniyan Esra Nasraldin Khalil Sharafaldin Harshini Muruganantham Jureerat Kijsomporn Ling Shing Wong Department of Applied Pharmaceutical Sciences and Clinical Pharmacy Faculty of Pharmacy Isra University Amman Jordan Department of Pharmaceutical Chemistry Faculty of Pharmacy Universiti Malaya Kuala Lumpur Malaysia Department of Medicinal Chemistry and Pharmacognosy Faculty of Pharmacy Jordan University of Science and Technology Irbid Jordan Department of Allied Medical Sciences Zarqa Private University Zarqa Jordan Department of Medical Sciences School of Medical and Life Sciences Sunway University Bandar Sunway Malaysia Department of Clinical Pharmacy and Pharmacy Practice Faculty of Pharmacy Universiti Malaya Kuala Lumpur Malaysia Center for Global Research Saveetha Medical College Saveetha Institute of Medical and Technical Sciences Saveetha University Chennai India School of Nursing Metharath University Bangtoey Thailand Faculty of Health and Life Sciences INTI International University Nilai Malaysia

Anxiety is a significant mental health issue that substantially affects an individual’s quality of life. Feelings of uneasiness, irritability, and sleep disturbances characterize it. 4-Hydroxyphenyl acetic acid (4-HPAA) is identified in brain cells as a physiological byproduct of tyramine. This study hypothesizes that 4-HPAA may regulate anxiety due to its anxiolytic properties, acting as a modulator of the GABAergic system, which plays a crucial role in the pathophysiology of anxiety disorders. Our study aims to enhance the anxiolytic effects of 4-HPAA through chemical modification to improve its pharmacokinetic properties. Three derivatives, namely Isopropyl-4-hydroxy-[phenyl] acetate (IHPA), Isopropyl-4-hydroxy-[phenyl] acetate (MPAA), and 4-methoxyphenyl acetate (MPHA), have been synthesized from 4-HPAA. This assessment will use well-established animal models, specifically the Elevated Plus-Maze (EPM) and Zero Maze (EZM) tests, selected for their validity in replicating anxiety-like symptoms in animals. Chronic caffeine administration via drinking water (0.3 g/l for 14 days) was employed to induce an anxiety state for testing purposes. IHPA and MPAA demonstrated significant anxiolyticactivity when tested in the EPM and EZM experiments. Molecular docking simulations using AutoDock Vina indicated that 4-HPAA derivatives had docking scores ranging from −5.8 to −4.8 kcal/mol, compared to the standard anxiolytic medication Diazepam, which scored −7.1 kcal/mol. These scores suggest a potential for 4-HPAA derivatives to interact effectively with the Gamma-aminobutyric acid (GABA_A) receptor. In conclusion, our in vivo and in silico analyses indicate a promising anxiolytic potential for 4-HPAA derivatives.

关键词： Anxiolytics 4-HPAA Molecular Docking Elevated Plus-Maze Zero Maze Tests

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The Harrat Al-Birk basalts in southwest Saudi Arabia:characteristic alkali mafic magmatism related to Red Sea rifting

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Acta Geochimica 2017年第1期36卷 74-88页

作者： rami A. Bakhsh Department of Mineral Resources and Rocks Faculty of Earth Sciences King Abdulaziz UniversityP.O. Box 80206 Jeddah 21589 Saudi Arabia

Harrat Al-Birk volcanics are products of the Red Sea rift in southwest Saudi Arabia that started in the Tertiary and reached its climax at ~ 5 *** volcanic field is almost monotonous and is dominated by basalts that include mafic-ultramafic mantle xenoliths(gabbro,websterite,and garnet-clinopyroxenite).The present work presents the first detailed petrographic and geochemical notes about the *** comprise vesicular basalt,porphyritic basalt,and flow-textured basalt,in addition to red and black ***,the volcanic rock varieties of the Harrat Al-Birk are low- to medium-Ti,sodic-alkaline olivine basalts with an enriched oceanic island signature but extruded in a within-plate *** is evidence of formation by partial melting with a sort of crystal fractionation dominated by clinopyroxene and Fe-Ti *** latter have abundant titanomagnetite and lesser *** is a remarkable enrichment of light rare earth elements and depletion in Ba,Th and K,Ta,and *** geochemical data in this work suggest Harrat Al-Birk basalts represent products of watersaturated melt that was silica *** melt was brought to the surface through partial melting of asthenospheric upper mantle that produced enriched oceanic island *** partial melting is the result of subducted continental mantle lithosphere with considerable mantle metasomatism of subducted oceanic lithosphere that might contain hydrous phases in its *** fractional crystallization process was controlled by significant separation of clinopyroxene followed by amphiboles and Fe-Ti oxides,particularly ***,the Harrat Al-Birk alkali basalts underwent crystal fractionation that is completely absent in the exotic mantle xenoliths(*** et *** The Pleistocene Jabal Akwa A1 Yamaniah maar/tuff ring-scoria cone complex as an analogy for future phreatomagmatic to magmatic explosive eruption scenarios in the Jizan Region,SW Saudi Arabia 201

关键词： Harrat Al-Birk Alkaline basalt Red Sea rifting Hydrous mantle Reworked oceanic crust

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Extra-Dimensional Cosmology with a Traversable Wormhole

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Chinese Physics Letters 2009年第9期26卷 37-40页

作者： EL-NABULSI Ahmad rami Department of Nuclear and Energy Engineering Cheju National University Ara-dong 1 Jeju 690-756 South Korea

We discuss many interesting and attractive features of a higher-dimensional cosmology with a static traversable wormhole dominated by a variable effective cosmological constant depending on the scale factor aft） as A... 详细信息

关键词： sea surface nonliear interaction numerical method

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