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Tai Chi in Parkinson’s Disease: A Preliminary Randomized, Controlled, and Rater-Blinded Study

Advances in Parkinson's Disease 2015年第1期4卷 9-12页

作者： Roger Kurlan Roye Evans Sandra Wrigley Shannon McPartland rami Bustami Ann Cotter Atlantic Neuroscience Institute Overlook Medical Center Summit NJ USA Integrative Medicine Atlantic Health System Morristown NJ USA Biostatistics Atlantic Health System Morristown NJ USA

Background: Given the limited benefits of current treatments for Parkinson’s disease (PD), inter-ventions that might provide supplementary benefits would be of value. The traditional Chinese medicine practice of Tai Chi has been said to improve some aspects of PD, particularly imbalance. Methods: Preliminary randomized, controlled, and rater-blinded clinical trial of Tai Chi, focusing on its effects on global motor, daily function, mood and quality of life. Subjects continued their standard medical therapy and were randomly assigned to Tai Chi (16 weekly classes, expert trainer, practice at home between classes) or no Tai Chi (control group) in a 2:1 ratio. The primary outcome measure was the total motor score of the Unified Parkinson’s Disease Rating Scale (UPDRS) and this was scored by an experienced rater who was blinded to the treatment assignment. The same rater scored the Schwab and England Activities of Daily Living Scale. The patient-completed Geriatric Depression Scale, PD (quality of life) Questionnaire-39, and fall diary were also analyzed. Results: 44 subjects participated with 29 assigned to Tai Chi and 15 serving as controls. Tai Chi was well-tolerated. Seven subjects withdrew prior to completion (2 from Tai Chi, 5 from control). We found no significant difference between treatment groups in the change in scores from baseline to end of intervention for any of the scales. Trends toward a benefit of Tai Chi were observed for individual UPDRS items (depression, finger tapping, hand movements, posture). Conclusions: Tai Chi does not appear to improve global measures in patients with PD. The practice may have benefits for PD, but these appear to be largely restricted to specific motor tasks and perhaps mood rather than being a global functional response. More study is needed to clarify and establish efficacy.

关键词： Parkinson’s Disease Tai Chi Mind-Body Treatment

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Expression and Clinical Significance of PIK3CA, c-METand c-KITMutations in Saudi Breast Cancer Patients

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Advances in Breast Cancer Research 2021年第3期10卷 60-74页

作者： rami Nassir Ghada Esheba Hanan M. Abd Elmoneim Ahlam S. Altowairqi Ghassan Nouman Department of Pathology School of Medicine Umm Al-Qura University Makkah Saudi Arabia Department of Pathology Faculty of Medicine Tanta University Tanta Egypt Department of Pathology Faculty of Medicine Minia University Minia Egypt Faculty of Nursing Umm Al-Qura University Makkah Saudi Arabia

Objective: PIK3CA is the most common pathway affected by mutations in breast cancer. PIK3CA/PTEN pathway is under intense investigation as a possible target for molecular therapy. Dysregulation PIK3CA/PTEN pathway is a substantial mechanism for the development of resistance to anti-HER2 therapy. Therefore, we aimed to study the PIK3CA/PTEN in breast cancer patients in Saudi population. Methods: We applied PTEN immunohistochemistry on 98 patients. Then, we applied next-generation sequencing to determine the genetic variations associated with the development of breast cancer and their correlations with clinicopathological variables. Results: PTEN expression was significantly correlated with lymph node metastasis (LNM), tumor stage, lymphovascular invasion (LVI) and

关键词： PTEN PIK3CA c-MET c-KIT Breast Cancer

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基于嵌入式网格的裂缝性致密油储层压裂生产一体化数值模拟方法

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计算物理 2024年

作者：徐世乾郭建春 Younis M.rami 卢聪西南石油大学油气藏地质及开发工程国家重点实验室 Texas A&M University， Harold Vance Department of Petroleum Engineering， College Station

有效的一体化模拟裂缝性致密油储层压裂生产过程是评价压裂设计的关键之一。为此，基于嵌入式网格的基质裂缝全域空间流固耦合数值模拟方法，进一步考虑天然裂缝影响下裂缝动态扩展、低速非线性渗流、基质与裂缝应力敏感，实现了裂缝性... 详细信息

有效的一体化模拟裂缝性致密油储层压裂生产过程是评价压裂设计的关键之一。为此，基于嵌入式网格的基质裂缝全域空间流固耦合数值模拟方法，进一步考虑天然裂缝影响下裂缝动态扩展、低速非线性渗流、基质与裂缝应力敏感，实现了裂缝性致密油储层压裂生产一体化多机理模拟。进而分析了天然裂缝、非线性渗流对裂缝扩展及生产动态的一体化影响规律。研究结果表明：模型可以在生产过程中任意时刻模拟压裂，为重复压裂、加密井的设计分析提供了有效工具。当基质岩石的抗拉强度由10.2 MPa降到2.3 MPa时，破碎带逐渐增大，滤失作用增加，导致主裂缝长度降低8%-9%，但可以增加累产油量17.5%至61.1%，影响作用显著且主要影响早期的日产油量。与启动压力梯度模型相比，低速非线性渗流可以更好地预测致密油生产动态。该方法为裂缝性致密油储层压裂生产一体化的动态预测、规律分析、工艺优化提供了高效工具。

关键词：致密油裂缝性储层流固耦合压裂生产一体化嵌入式网格

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Application of near-infrared spectroscopy for fast germplasm analysis and classification in multi-environment using intact-seed peanut(Arachis hypogaea L.)

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Oil Crop Science 2024年第2期9卷 132-141页

作者： Fentanesh Chekole Kassie Gilles Chaix Hermine Bille Ngalle Maguette Seye Coura Fall Hodo-Abalo Tossim Aissatou Sambou Olivier Gibert Fabrice Davrieux Joseph Martin Bell Jean-Francois rami Daniel Fonceka Joel Romaric Nguepjop Department of Plant Biology and Physiology Faculty of SciencesUniversity of Yaounde IYaoundeP.O.Box 337Cameroon Department of Plant Science College of AgricultureWolaita Sodo UniversitySodoP.O.Box 138Ethiopia CIRAD UMR AGAP InstitutMontpellierFrance AGAP Institut Univ MontpellierCIRADINRAEInstitut AgroMontpellierFrance ChemHouse Research Group MontpellierFrance Centre D’Etudes Regional Pour L’Amelioration de L’Adaptation a La Secheresse(CERAAS/ISRA) Route de KhomboleThiesBP 3320Senegal Dispositif de Recherche et de Formation en Partenariat Innovation et Amelioration Varietale en Afrique de L’Ouest(IAVAO)CERAASRoute de KhomboleThiesBP 3320Senegal CIRAD UMR QUALISUDSaint PierreFrance

Peanut is a worldwide oilseed crop and the need to assess germplasm in a non-destructive manner is important for seed nutritional *** this study,Near Infrared Spectroscopy(NIRS)was applied to rapidly assess germplasm variability from whole seed of 699 samples,field-collected and assembled in four genetic and environmentbased sets:one set of 300 varieties of a core-collection and three sets of 133 genotypes of an interspecific population,evaluated in three environments in a large spatial scale of two countries,Mbalmayo and Bafia in Cameroon and Nioro in Senegal,under rainfed *** elemental spectra were gathered on six subsets of seeds of each sample,after three rotation scans,with a spectral resolution of 16 cm-1over the spectral range of867 nm to 2530 *** were then processed by principal component analysis(PCA)coupled with Partial least squares-discriminant analysis(PLS-DA).As results,a huge variability was found between varieties and genotypes for all NIR wavelength within and between *** magnitude of genetic variation was particularly observed at 11 relevant wavelengths such as 1723 nm,usually related to oil content and fatty acid *** yielded the most chemical attributes in three significant PCs(i.e.,eigenvalues>10),which together captured 93%of the total variation,revealing genetic and environment structure of varieties and genotypes into four clusters,corresponding to the four samples *** pattern of genetic variability of the interspecific population covers,remarkably half of spectrum of the core-collection,turning out to be the ***,a PLS-DA model was developed and a strong accuracy of 99.6%was achieved for the four sets,aiming to classify each seed sample according to environment *** confusion matrix achieved for the two sets of Bafia and Nioro showed 100%of instances classified correctly with 100%at both sensitivity and specificity,confirming that their seed quality was different f

关键词： Groundnut Oilseed Near infrared spectroscopy Germplasm analysis Environment Nutritional Breeding

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炎热季节鸡的饲养管理

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国外畜牧科技 1991年第3期18卷 36-38页

作者： rami Cobb 李荫

在夏季,工厂化养鸡提高经济效益的难度较大,因为本身存在着鸡密度大、易生病、要随时调整鸡营养供给及环境条件的问题。而且现代化家禽品种对高温、高湿的反应很敏感。鸡最适宜的温度为20～25℃,当气温升到32℃以上时,就会发生热应激。

关键词：鸡饲养管理夏季

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基于复杂网络分析的中国在沙特高速公路建设项目关键风险研究

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公路工程 2023年第6期48卷 184-188页

作者： ALOTAIBI rami TALAL T 大连理工大学建设工程学院辽宁大连116024

针对海外高速公路建设项目风险类别多样、风险关系复杂、风险管理水平有限的问题,应用复杂网络理论研究中国在沙特阿拉伯的高速公路建设项目的关键风险,采用调查问卷的方式确定风险因素和相关关系,构建风险关系网络。应用K核理论和Lambd... 详细信息

针对海外高速公路建设项目风险类别多样、风险关系复杂、风险管理水平有限的问题,应用复杂网络理论研究中国在沙特阿拉伯的高速公路建设项目的关键风险,采用调查问卷的方式确定风险因素和相关关系,构建风险关系网络。应用K核理论和Lambda集合分析关键风险子网络和风险传递规律,识别得到关键风险因素,并制定相应的风险管控和治理措施。该方法能够较为准确和快速地判断工程项目中的关键性风险因素,可操作性较强。

关键词：复杂网络沙特阿拉伯高速公路建设项目关键风险

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Digital reconstruction of ancient Egyptian tombs

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Journal of Southeast University(English Edition) 2007年第2期23卷 250-254页

作者：艾比塔龚恺东南大学建筑学院南京210096

From the pyramids of Giza to the tombs of Thebes at Luxor, the glorious ancient Egyptian history has produced remarkable architecture. Sadly, tourists, numbering nearly four million per year, have taken a heavy toll on many of these ancient structures. Of particular concern are many of tombs located opposite Luxor on the western bank of the Nile. Digital reconstruction of these tombs has the potential of helping to document and preserve these important historical structures. Issues concernng new and unique problems involving the photographing and digital reconstruction of these tombs are addressed. Techniques for removing image distortions, recovering 3-D shapes and correcting for lighting imbalances are discussed. A complete reconstruction of the tomb of Sennediem is shown.

关键词： tomb conservation digital reconstruction photographing

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基于结构性能的自由曲面单层网壳结构网格形状优化

基于结构性能的自由曲面单层网壳结构网格形状优化

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作者：阿赞（AZAN rami MOHAMMED YAHYA）东南大学

学位级别：硕士

本文主要研究基于结构性能的自由曲面单层网壳结构网格形状优化问题。从实际工程中提取四边支撑单层网格单元结构并作为案例研究;然后,使用NURBS曲线表示四边支撑单层网格的曲面。Rhino和Grasshopper软件用于生成三种类型的单层网格,即... 详细信息

本文主要研究基于结构性能的自由曲面单层网壳结构网格形状优化问题。从实际工程中提取四边支撑单层网格单元结构并作为案例研究;然后,使用NURBS曲线表示四边支撑单层网格的曲面。Rhino和Grasshopper软件用于生成三种类型的单层网格,即四边支撑三角形网格、对角单层网格和组合三角形/六角形单层网格。四边支撑三角形单层网格导致了大量元素和高节点复杂度,因为每个节点中通常有六个元素相交。相比之下,对于四边支撑的对角单层网格和四边支撑的三角形/六角形单层网格,每个节点仅连接四个元素,这反过来又导致元素数量分别减少31.24%和46.81%。采用SAP2000进行有限元建模,研究了生成的网格在重力和风荷载作用下的结构性能,发现四边支撑三角形单层网格在抗弯和稳定性方面具有更好的结构性能。此外,四边支撑三角形单层网格和三角形/六角形组合单层网格与四边支撑对角单层网格相比具有均匀的应力分布。为了研究四边支撑单层网格与高跨比之间的关系,采用了三种不同的高跨比。其中实际高跨比为6.3%,然后分别增加到12.6%和18.9%。结果表明,四边支撑三角形、对角线和三角形/六角形组合单层网格在高跨比为18.9%时具有更好的结构性能,因为在该高跨比下,这些网格对垂直挠度的抵抗力更好,与6.3%和12.6%的高跨比相比,这些网格的构件内力更小。此外,在高跨比为18.9%时,四边支撑单层网格的用钢量小于其他两种高跨比下的网格用钢量。三种网格形状中,三角形网格形状的结构性能最佳。最后,将所研究结果用于实际工程分析。

关键词：网壳结构自由曲面形状优化结构性能高跨比 FEM

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Extraperitoneal robot-assisted radical prostatectomy: Comparison with transperitoneal technique

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World Journal of Clinical Urology 2013年第2期2卷 3-9页

作者： Chris Anderson Ben Ayres rami Issa Matthew Perry Evangelos Liatsikos Jens-Uwe Stolzenburg Khurshid R Ghani Department of Urology St George’s HospitalSt George’s Healthcare NHS TrustLondon SW17 0JTUnited Kingdom Department of Urology University of Patras School of Medicine26500 RIO PatrasGreece Department of Urology University of Leipzig04103 LeipzigGermany Vattikuti Urology Institute Henry Ford HospitalDetroitMI 48202United States

AIM: To determine peri-operative, oncological, functional and safety profiles of extraperitoneal robot-assisted radical prostatectomy(e RARP) vs transperitoneal robot-assisted radical prostatectomy(t RARP) in a single ***: A total of 120 consecutive patients underwent 50 e RARP and 70 e RARP operations respectively by the same surgical team. Peri-operative and post-operative outcomes including blood loss, hospitalization, complications(Clavien grade), positive surgical margin(PSM) rates, continence and erectile function were compared. The performance of e RARP required several technical modifications. These included developmentof Retzius' space by balloon insufflation, laparoscopic dissection of lateral extensions of this area; caudal port positioning; cranial digital stripping of peritoneum for sucker port and lodging the bagged prostate specimen adjacent to the lateral assistant port to permit space for urethro-vesical ***: Robotic console times were shorter with e RARP vs t RARP(145.1 min vs 198.3 min, P < 0.0001). There were no significant differences in blood loss, PSM rates(e RARP 17.7% vs t RARP 22%) or complications(e RARP 8.5% vs t RARP 8%). A drain was used in all patients after t RARP and in 25/70 e RARP cases. Length of hospital stay was shorter after e RARP(mean 1.94 d vs 3.6 d, P < 0.0002). There were no differences between techniques in continence or potency at 6 mo. e RARP required several technical modifications: development of Retzius' space by balloon insufflation, laparoscopic dissection of lateral extensions of this area; caudal port positioning; and lodging the bagged prostate specimen adjacent to the lateral assistant port to permit space for urethro-vesical ***: e RARP demonstrated advantages in surgical times, hospital stay and equivalence in PSM rates, complications and functional outcomes. e RARP is a useful alternative to t RARP especially in patients with adhesions, pre-existing inguinal hern

关键词： Prostatic neoplasms Robotics Laparoscopy Prostatectomy Complications

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Cytomegalovirus positive ulcerative colitis:A single center experience and literature review

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World Journal of Gastrointestinal Pathophysiology 2013年第1期4卷 18-23页

作者： Uri Kopylov Gila Sasson Bella Geyshis Michal Tepperberg Oikawa Iris Barshack rami Eliakim Shomron Ben-Horin Department of Gastroenterology Sheba Medical CenterRamat Gan 52621Israel Internal Medicine D Sheba Medical CenterRamat Gan 52621Israel Central Virology Laboratory Public Health LaboratoriesIsrael Ministry of HealthRamat Gan 52621Israel Department of Pathology Sheba Medical CenterRamat Gan 52621Israel

AIM:To compare the clinical outcome of cytomegalovirus(CMV)-positive ulcerative colitis(UC) patients with and without antiviral ***:This was a retrospective case-controlled *** database of UC patients in our institution was scanned for documented presence of CMV on colonic ***,clinical data,endoscopy findings and pathology reports were extracted from the patients' charts and electronic *** available,the data from colonoscopies preceding and following the diagnosis of colonic CMV infection were also *** primary outcomes of the study were colectomy/death during hospitalization and the secondary outcomes were colectomy/death through the course of the ***:Thirteen patients were included in the study,7(53.5%) of them were treated with gancyclovir and 6(46.5%) were *** treated with antivirals presented with a more severe disease and 57% of them were treated with cyclosporine or infliximab before initiation of gancyclovir,while none of the patients without antivirals required rescue *** patient died and another patient underwent urgent colectomy during hospitalization,both of them from the gancyclovir-treatment *** the entire follow-up time(13 ± 13 mo),a total of 3 colectomies and one death occurred,all among the antiviral-treated patients(for colectomy:3/7 vs 0/6 patients,P = 0.19;for combined adverse outcome:4/7 vs 0/6 patients,P = 0.07).In 9/13 patients,immunohistochemistry for CMV was performed on biopsies obtained during a subsequent colonoscopy and was positive in one patient ***:Gancyclovir-treated patients had a more severe disease and outcome,probably unrelated to antiviral ***-CMV-positive patients with mild disease may recover without antiviral therapy.

关键词： Ulcerative colitis Cytomegalovirus Gancyclovir Cyclosporine Immunohistochemistry

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