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使用高分辨色质联机AUTOSPEC-ULTIMANT分析二噁英及呋喃

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环境化学 2008年第6期27卷 856-858页

作者： Keith Worrall Anthony Newton ramesh rao 沃特世公司英国曼彻斯特

“二噁英”是指具有相似化学结构和生物特征的一族化合物，分别属于三大类别：多氯代二苯并二嗯英（PCDDs），多氯代二苯并呋喃（PCDFs）以及多氯联苯（PCBs）．PCDDs和PCDFs无商业目的性生产，而是在大量的人类活动中产生的．

关键词：多氯代二苯并呋喃二噁英色质联机高分辨 PCDFs PCDDs 生物特征化学结构

用GC-三级四极杆MS/MS一次进样筛选鱼和飞灰样品基质中四至八氯代PCDD/Fs的方法

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环境化学 2006年第4期25卷 524-527页

作者： Keith Worrall Anthony Newton ramesh rao David Wood 单位不详

用高分离能力的气相色谱-高分辨质谱（HRGC-HRMS）核实二噁英／呋喃是一项昂贵又费时的分析工作，需要高素质的仪器操作人员，而在认证分析前采用筛选法检查样品是检测不出还是浓度超出HRGC-HRMS方法定量范围，可以大大地减少HRGC-HRMS... 详细信息

用高分离能力的气相色谱-高分辨质谱（HRGC-HRMS）核实二噁英／呋喃是一项昂贵又费时的分析工作，需要高素质的仪器操作人员，而在认证分析前采用筛选法检查样品是检测不出还是浓度超出HRGC-HRMS方法定量范围，可以大大地减少HRGC-HRMS实验室的工作负荷．最新提供的信息表明约10％筛选过的样品需用HRGC-HRMS认证／核实。有些GC／MS／MS方法需要多次进样以获得有毒和无毒的PCDD／Fs，或用功能变换法可以确保检测出所有的有毒的2，3，7，8-氯代PCDD／Fs，但损失某些无毒的PCDD／Fs（2，3，7，8氯代PCDD／Fs除外）．

关键词： PCDD/Fs 一次进样筛选法 MS/MS 氯代样品四极杆基质飞灰三级

用Autospec-Ultima NT气相色谱-高分辨质谱分析二噁英及相关的持久性有机污染物

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环境化学 2006年第5期25卷 661-663页

作者： Keith Worrall Anthony Newton Clive Robinson ramesh rao 单位不详

“二噁英”是指一类化学结构和生物特征均有某些相似之处的化合物．这些有毒化合物有几百种，可分为相关的三大类：氯代二苯并-对-二噁英（CDDs），氯代二苯并呋喃（CDFs）和某些多氯代联苯（PCBs）．CDDs和CDFs并非与生具有，而是由于... 详细信息

“二噁英”是指一类化学结构和生物特征均有某些相似之处的化合物．这些有毒化合物有几百种，可分为相关的三大类：氯代二苯并-对-二噁英（CDDs），氯代二苯并呋喃（CDFs）和某些多氯代联苯（PCBs）．CDDs和CDFs并非与生具有，而是由于人类活动不注意而生成的．天然过程也会产生CDDs和CDFs．

关键词： Autospec-Ultima NT 高分辨质谱分析二噁英

Determination of Capsaicin Induced Increase in Dermal Blood Flow Using Laser Doppler Flowmetry Technique

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Pharmacology & Pharmacy 2011年第3期2卷 159-163页

作者： Sunil Kumar Reddy Khambam Madireddy Umamaheshwar rao Naidu Pingali Usha Rani Takallapalli ramesh Kumar rao 不详

In the present study, we evaluated laser Doppler flowmetry technique using LDF100C (Biopac systems) by determining blood flow changes following acute application of capsaicin on 12 healthy human subjects. Capsaicin applied locally (topical application) at a dose of 0.075% produced significant increase in mean dermal blood flow from 31.4 ± 3.1 Blood Perfusion Units (BPU) to 115. 7 ± 24.6 Blood Perfusion Units (BPU) after 30 minutes, also there was significant difference in dermal blood flow change between placebo (32.1 ± 2.7 BPU) and capsaicin (115.7 ± 24.6 BPU) applica- tion. Capsaicin application produced significant percentage change in dermal blood flow by 291.0 ± 85.3% from baseline, while the change was insignificant with placebo (13.2 ± 7.4%). Therefore, it is suggested that this technique which is technically sound, non-invasive and inexpensive can be adopted in various fields of research to determine blood flow changes and this technique can also be utilized to determine the antagonists of the mediators involved in capsaicin induced vasodilatation.

关键词： Pharmacodynamics Neurogenic Inflammation Capsaicin

Localization via TDOA in a UWB sensor network using Neural Networks

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Localization via TDOA in a UWB sensor network using Neural N...

A Prospective, Multicentric, Post Marketing Surveillance to Evaluate Efficacy & Safety of Ranitidine HCl (150 & 300 mg IR/CR) in Indian Patients with Gastroesophageal Reflux Disease (PROGRADE)

2008 IEEE International Conference on Communications(ICC 2008)

作者： Salih Ergt ramesh R.rao zgr Dural Zafer Sahinoglu ECE Department University of California Qualcomm Inc.5775 Morehouse Dr.San DiegoCA 92121 Mitsubishi Electric Research Laboratories 201 Broadway Cambridge MA 02139

In an Ultra-wide band （UWB） sensor network signal reflections from objects can be used to accurately determine the *** signals are preferred in these types of sensor networks since they provide a very good resolution due to their fine time *** propose an artificial neural network based localization algorithm to detect single object in a sensor network and compare its performance to Cramer-rao bound and least squares *** we propose a two phase algorithm for multiple object detection and evaluate the algorithm for the case when there are two objects in a sensor network with three nodes.

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Open Journal of Gastroenterology 2023年第7期13卷 237-249页

作者： Akash Shukla Anil Kumar Awasthi ramesh rao Dawesh Prakash Yadav Nilesh Nolkha Rajesh Pendlimari Sanjiv Dua Shrish Bhatnagar Ravindra Mote Ashish Birla Jay Savai Kapil Mehta Shashank Salunke Department of Gastroenterology Gastro Universe Mumbai India Department of Medicine Ajanta Research Centre Ajanta Hospital & IVF Centre Lucknow India Departmentof Nephrology Sanjeevani Kidney Care Mumbai India Department of Gastroenterology Institute of Medical Sciences Banaras Hindu University Varanasi India Department of Rheumatology Wockhardt Hospitals Mumbai India Department of Gastroenterology Rajalakshmi Hospital and Research Center Bangalore India Department of General Surgery SaiKripa Hospital Mumbai India Department of Gastroenterology Sparsh Child Care and Gastro Centre Lucknow India Department of Clinical Research Mediclin Clinical Research Mumbai India Department of Medical Affairs JB Chemicals & Pharmaceuticals Ltd. Mumbai India

Purpose: Ranitidine hydrochloride (HCl) remains an important medication for treating acid-peptic ailments such as Gastroesophageal reflux disease (GERD). The main objective of this Post Marketing Surveillance (PMS) clinical study was to test the efficacy and safety of Ranitidine HCl in Indian patients suffering from GERD. Patients and Methods: Data of 2446 patients (1307 males;1121 females) from 21 centers across India were analyzed. Patients received either of the three treatments: Ranitidine HCl 150 mg twice a day (BID) (ARM-A), Ranitidine HCl 300 mg once daily (OD) or BID (ARM-B), and Ranitidine HCl 300 mg OD (ARM-C). Gastroesophageal Reflux Disease Symptom Assessment Scale (GSAS) score and Heartburn Severity score were used to assess the drug’s efficacy. The adverse events reported by patients or investigators were analyzed to assess the safety profile of Ranitidine. Results: Of the 2446 subjects screened, 2428 were enrolled. There was a significant reduction in GSAS scores from baseline to the end of the study visit in all three ARMs. The GSAS scores reduced from 2.02 to 0.23 in ARM-A, 2.01 to 0.24 in ARM-B, and 2.07 to 0.26 in ARM-C patients. In ARM A, 72.82% had 24 hours heartburn-free days, and 66.89% had 7 consecutive heartburn-free days, which was more significant than the other two ARMs. 128 (5.27%) patients reported ADRs due to Ranitidine HCl at different doses. The most frequently reported ADR was constipation (17.18%), followed by oliguria (14.06%), cold (13.28%), and dysuria (12.5%). Of 128 ADRs, 113 (88.28%) were mild, and only 11 (8.59%) ADRs were related to the study drug. No severe ADRs were reported during the study. Conclusion: Ranitidine HCl 150/300 mg tablet was found to be an effective and safe H2-receptor antagonist for treating GERD in Indian Patients.

关键词： Ranitidine Hydrochloride GERD Heartburn H2-Receptor Antagonists

Millimeter wave dielectric loaded exponentially tapered slot antenna array using substrate integrated waveguide for gigabit wireless communications

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红外与毫米波学报 2015年第5期34卷 513-519页

作者： S ramesh T Rama rao Department of Electronics & communication Engineering Valliammai Engineering College RADMIC Department of Telecommunication EngineeringSRM University

A new and upcoming application is the use of 60 GHz antennas for high date rate point-to-point connections to serve Gigabit(Gi-Fi)w ireless *** design of M illimeter w ave(M m W)antennas has to cope w ith the unadorned influences of manufacturing tolerances and losses at 60 *** this paper,the concept of Substrate Integrated Waveguide(SIW)and Exponentially Tapered Slot(ETS)antenna w ere used together to design a high gain,efficient planar dielectric loaded antenna for M m W Gi-Fi w ireless communications at 60 *** SIW is used to feed the antenna and a dielectric is utilized in front of the antenna to increase the *** dielectric loaded ETS antenna and compact SIW feed w ere fabricated on a single substrate,resulting in low cost and easy *** antenna w ith elliptical shaped dielectric loaded w as fabricated using printed circuit board *** measured gain of the single element antenna is 10.2 dB,w hile the radiation efficiency of 96.84%is obtained at 60 *** Y-junction SIW pow er divider is used to form a 1×4 array structure.M easured gain of the 1×4 array antenna is 13.3 dB,w hile the measured radiation pattern and gain are almost constant w ithin the w ide bandw idth of the antenna.

关键词： millimeter waves 60 GHz exponentially tapered slot antenna dielectric loading substrate integrated waveguide

Determination of Capsaicin Induced Increase in Dermal Blood Flow Using Laser Doppler Flowmetry Technique

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Modeling and multi-response optimization of machining performance while turning hardened steel with self-propelled rotary tool

Pharmacology & Pharmacy（药理与制药） 2011年第3期

作者： Sunil Kumar Reddy Khambam Madireddy Umamaheshwar rao Naidu Pingali Usha Rani Takallapalli ramesh Kumar rao

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Advances in Manufacturing 2015年第1期3卷 84-95页

作者： Thella Babu rao A.Gopala Krishna ramesh Kumar Katta Konjeti Rama Krishna Department of Mechanical Engineering GITAM UniversityHyderabad 502329Andhra PradeshIndia Department of Mechanical Engineering University College of EngineeringJNTUKKakinada 533003Andhra PradeshIndia Productionisation & Technology Transfer Defence R&D LaboratoryKanchanbaghHyderabad 500058Andhra PradeshIndia

There are many advanced tooling approaches in metal cutting to enhance the cutting tool performance for machining hard-to-cut materials. The self propelled rotary tool （SPRT） is one of the novel approaches to improve the cutting tool performance by providing cutting edge in the form of a disk, which rotates about its principal axis and provides a rest period for the cutting edge to cool and allow engaging a fresh cutting edge with the work piece. This paper aimed to present the cutting performance of SPRT while turning hardened EN24 steel and optimize the machining conditions. Surface roughness （Ra） and metal removal rate （rMMR） are considered as machining perfor- mance parameters to evaluate, while the horizontal incli- nation angle of the SPRT, depth of cut, feed rate and spindle speed are considered as process variables. Initially, design of experiments （DOEs） is employed to minimize the number of experiments. For each set of chosen process variables, the machining experiments are conducted on computer numerical control （CNC） lathe to measure the machining responses. Then, the response surface method- ology （RSM） is used to establish quantitative relationships for the output responses in terms of the input variables. Analysis of variance （ANOVA） is used to check the adequacy of the model. The influence of input variables on the output responses is also determined. Consequently, these models are formulated as a multi-response optimi- zation problem to minimize the Ra and maximize the rMMR simultaneously. Non-dominated sorting genetic algorithm-II （NSGA-II） is used to derive the set of Pareto-optimal solutions. The optimal results obtained through the pro- posed methodology are also compared with the results of validation experimental runs and good correlation is found between them.

关键词： Self-propelled rotary turning ~ Empiricalmodeling ~ Response surface methodology (RSM) - Multi-objective formulation - Optimization - Non-dominatedsorting genetic algorithm-II (NSGA-II)