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Communications in Theoretical Physics 2019年第7期71卷 779-792页

作者： rakesh kumar Ravinder kumar Reena Koundal Sabir Ali Shehzad Mohsen Sheikholeslami Department of Mathematics Central University of Himachal PradeshDharamshalaIndia Department of Mathematics COMSATS University IslamabadSahiwal 57000Pakistan Department of Mechanical Engineering Babol Noshirvani University of TechnologyBabolIran

In this problem,simultaneous effects of Joule and viscous dissipation in three-dimensional flow of nanoliquid have been addressed in slip flow regime under time dependent rotational *** nanoparticles are submerged in the base fluid(water)due to their chemical and biological *** increment the novelty,effects of cubic autocatalysis chemical reactions and radiative heat transfer have been incorporated in the related boundary layer *** partial differential system is solved by employing the proposed implicit finite difference *** conditions and stability criteria are obtained to ensure the convergence and accuracy of solutions.A comparative analysis is proposed for no-slip nanofluid flow(NSNF)and slip nanofluid flow(SNF).Variations in skin-friction coefficients,Sherwood and Nusselt numbers against physical parameters are *** is investigated that velocity slip and temperature jump significantly control drag forces and rate of heat transfer.

关键词： cubic autocatalysis reactions viscous dissipation Joule heating rotating-fluctuating environment slip flow regime

Analysis of isoquinoline alkaloids from Mahonia leschenaultia and Mahonia napaulensis roots using UHPLC-Orbitrap-MSn and UHPLC-QqQ LIT-MS/MS

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Journal of Pharmaceutical Analysis 2017年第2期7卷 77-86页

作者： Awantika singh Vikas Bajpai Sunil kumar Ajay kumar singh Rawat Brijesh kumar Sophisticated Analytical Instrument Facility Division CSIR-Central Drug Research InstituteLucknow 226031India Academy of Scientific and Innovative Research New Delhi 110001India Pharmacognosy and Ethnopharmacology Division CSIR-National Botanical Research InstituteLucknow 226001India

Mahonia leschenaultia（ML） and Mahonia napaulensis（MN） are less known and unexplored medicinal plants of the family Berberidaceae. They are used by the Todas of Nilgiris in their religious and medical practices but chemically less identified. Hence, we decided to do extensive phytochemical analysis to explore the potential of these plant extracts. An ultrahigh performance electrospray tandem mass spectrometry（UHPLC-ESI-MS/MS）method was successfully developed for qualitative analysis of the bioactive components in Mahonia species using Orbitrap Velos Pro mass spectrometer. Sixteen compounds were identified by comparison of their retention times and mass spectra（MS） with authentic standards and reported literature. Multi-stage mass spectra（MS（2-8）） for the identification of protoberberine and aporphine alkaloids showed the sequential expulsion of all the substituents attached with their basic skeleton followed by CO loss. Eight of the identified compounds（berberine, jatrorrhizine, palmatine, magnoflorine, isocorydine, glaucine, tetrahydropalmatine and tetrahydroberberine） were simultaneously determined by another UHPLC-ESI-MS/MS method under the multiple reactions monitoring（MRM） mode quantitatively using triple quadrupole linear ion trap mass spectrometer. The analytical method was validated for 8 bioactive compounds with overall recovery in the range98.5%-103.6%（RSD≤2.2%）, precise（RSD≤2.07%） and linear（r≥0.9995） over the concentration range of 0.5-1000 ng/mL and successfully applied in ML and MN roots, which suggests the suitability of the proposed approach for the routine analysis of Mahonia species and their quality control.

关键词： Orbitrap-MS QqQLIT-MS Mahonia leschenaultia Mahonia napaulensis Isoquinoline alkaloids

Sexual dysfunctions and their treatment in liver diseases

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World Journal of Hepatology 2022年第8期14卷 1530-1540页

作者： rakesh kumar Jagdish Department of Hepatology Gastroenterology and Liver Transplant MedicineFortis Hospital NoidaNoida 201301UPIndia

Sexual dysfunction(SD)is a prevalent but very commonly ignored aspect in the treatment of liver diseases and *** etiology of SD is multifactorial and therefore treatment strategies are complex,especially in *** inhibitors are useful and effective in erectile dysfunction in males but in females,no single drug is available for SD,therefore multimodal treatment is required depending upon the *** foremost and fundamental requirement in both genders is to be stress-free and have adequate control of liver *** quality of life is helpful in improving SD and vice versa is also ***,patients suffering from liver diseases should come forward and ask for treatment for SD,and physicians should actively enquire about SD while history taking and evaluating these *** results in deterioration of quality of life,and both are modifiable and treatable aspects of liver diseases,which are never addressed actively,due to social taboos and fears of SD treatment in the presence of liver *** diagnosis of SD does not require costly investigations,as the diagnosis can be established based on validated questionnaires available for both genders,therefore detailed targeted history taking using questionnaires is *** are emerging in this area but is still at an early *** studies should be dedicated to SD in liver diseases.

关键词： Sexual dysfunction Erectile dysfunction Female sexual function index International index of erectile function Phosphodiesterase inhibitors Hepatic venous pressure gradient

Genetic diversity analysis of Lepidium sativum(Chandrasur) using inter simple sequence repeat(ISSR) markers

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Journal of Forestry Research 2015年第1期26卷 107-114页

作者： Amandeep Kaur rakesh kumar Suman Rani Anita Grewal Department of Biotechnology University Institute of Engineering & Technology Kurukshetra University

Lepidium sativum（commonly known as garden cress） belongs to the family Brassicaceae. It is a fastgrowing erect, annual herbaceous plant. Its seeds possess significant fracture healing, anti-asthmatic, anti-diabetic,hypoglycemic, nephrocurative and nephroprotective activities. In the present study, we assessed the genetic diversity of various genotypes of L. sativum using inter-simple sequence repeat（ISSR） markers. Out of 41 ISSR primers screened, 32 primers showed significant, clear and reproducible bands. A total of 510 amplified bands were obtained using 32 ISSR primers, out of which 422 bands were polymorphic and 88 bands were monomorphic. The percentage of polymorphism was found to be 82. A total of 35 unique alleles ranging insize from 200 to 2,900 bp were *** analysis based on unweighted pair-group method,arithmetic mean divided the 18 genotypes into two main clusters, with the first having only HCS-08 genotype of *** and other having all of the other 17 genotypes. The Jaccard similarity coefficient revealed a broad range32–72 % genetic relatedness among the 18 genotypes.

关键词： ISSR Genetic diversity Polymorphism Lepidium sativum Cluster analysis

A comprehensive review on pharmacognosy, phytochemistry and pharmacological activities of 8 potent Prunus species of southeast Asia

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Journal of Traditional Chinese Medicine 2024年第3期44卷 620-628页

作者： Shikha Agrawal Adarsh kumar Ankit kumar singh Harshwardhan singh Suresh Thareja Pradeep kumar Department of Pharmaceutical Sciences and Natural Products Central University of PunjabBathinda 151401India

Genus Prunus comprising around 430 species is a vast important genus of family Rosaceae, subfamily amygdalaoidae. Among all 430 species, around 19 important species are commonly found in Indian subcontinent due to their broad nutritional and economic importance. Some most common species of genus Prunus are Prunus amygdalus, Prunus persica, Prunus armeniaca, Prunus avium, Prunus cerasus, Prunus cerasoides, Prunus domestica, Prunus mahaleb, etc. A newly introduced species of Prunus i.e Prunus sunhangii is recently discovered which is morphologically very similar to Prunus cerasoides. Plants of Prunus species are short to medium-sized deciduous trees mainly found in the northern hemisphere. In India and its subcontinent,it extends from the Himalayas to Sikkim, Meghalaya,Bhutan, Myanmar etc. Different Prunus species have been extensively studied for their morphological,microscopic, pharmacological and phytoconstituents characteristics. Total phenolic content of Prunus species explains the presence of phenols in high quantity and pharmacological activity due to phenols. Phytochemical screening of species of genus Prunus shows the presence of wide phytoconstituents which contributes in their pharmacological significance and reveals the therapeutic potential and traditional medicinal significance of this genus. Genus Prunus showed a potent antioxidant activity analyzed by 1,1-diphenyl-2-picryl-hydrazyl radical assay. Plant species belonging to the genus Prunus is widely used traditionally for the treatment of various disorders. Some specific Prunus species possess potent anticancer, anti-inflammatory,hypoglycemic etc. activity which makes the genus more interesting for further research and findings. This review is an attempt to summarize the comprehensive study of Prunus species from its distribution, morphological characters to phytoconstituents, and pharmacological activity.

关键词： Rosaceae Prunus antineoplastic agents hypoglycemic agents distribution phytochemistry review

Kinematic Modeling for Biped Robot Gait Trajectory Using Machine Learning Techniques

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Journal of Bionic Engineering 2022年第2期19卷 355-369页

作者： Bharat singh Ankit Vijayvargiya Rajesh kumar Department of Electrical Engineering Malaviya National Institute of TechnologyJaipur 302017India

This paper presents the predictive models for biped robot trajectory *** models are parametrizing as a continuous function of joint angle *** a previous work,the authors had collected the human locomotion dataset at RAMAN Lab,MNIT,Jaipur,*** MNIT gait dataset consists of walking data on a plane surface of 120 human subjects from different age groups and ***-two machine learning models(linear,support vector,k-nearest neighbor,ensemble,probabilistic,and deep learning)trained using the collected *** addition,two types of mapping,(a)one-to-one and(b)many-to-one,are presented for each *** mapping models act as a reference policy for the control of joints and prediction of state for the next time instant in advance if the onboard sensor *** show that the deep learning and probabilistic learning models perform better for both types of ***,the probabilistic model outperforms the deep learning-based models in terms of maximum error,because the probabilistic model effectively deals with the prediction *** addition,many-to-one outperforms the one-to-one mapping because it captures the correlation between knee,hip,and ankle ***,this study suggests a many-to-one mapping using the probabilistic model for biped robot trajectory generation.

关键词： Kinematic Locomotion Machine learning Prediction Regression

DNACDS:Cloud IoE big data security and accessing scheme based on DNA cryptography

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Frontiers of Computer Science 2024年第1期18卷 157-170页

作者： Ashish singh Abhinav kumar Suyel NAMASUDRA School of Computer Engineering KIIT Deemed to be UniversityBhubaneshwar 751024India Department of Computer Science and Engineering Indian Institute of Information Technology SuratSurat 394190India Department of Computer Science and Engineering National Institute of Technology AgartalaAgartala 799046India

The Internet of Everything(IoE)based cloud computing is one of the most prominent areas in the digital big data *** approach allows efficient infrastructure to store and access big real-time data and smart IoE services from the *** IoE-based cloud computing services are located at remote locations without the control of the data *** data owners mostly depend on the untrusted Cloud Service Provider(CSP)and do not know the implemented security *** lack of knowledge about security capabilities and control over data raises several security *** Acid(DNA)computing is a biological concept that can improve the security of IoE big *** IoE big data security scheme consists of the Station-to-Station Key Agreement Protocol(StS KAP)and Feistel cipher *** paper proposed a DNA-based cryptographic scheme and access control model(DNACDS)to solve IoE big data security and access *** experimental results illustrated that DNACDS performs better than other DNA-based security *** theoretical security analysis of the DNACDS shows better resistance capabilities.

关键词： IoE based cloud computing DNA cryptography IoE big data security StS KAP feistel cipher IoE big data access

Identification and characterization of phenolics and terpenoids from ethanolic extracts of Phyllanthus species by HPLC-ESI-QTOF-MS/MS

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Journal of Pharmaceutical Analysis 2017年第4期7卷 214-222页

作者： Sunil kumar Awantika singh Brijesh kumar Sophisticated Analytical Instrument Facility CSIR-Central Drug Research InstituteLucknow 226031Uttar PradeshIndia Academy of Scientific and Innovative Research (AcSIR) New Delhi 110025India

Phyllanthus species plants are a rich source of phenolics and widely used due to their medicinal properties. A liquid chromatography–tandem mass spectrometry(LC–MS/MS) method was developed using high-pressure liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry(HPLC-ESI-QTOFMS/MS) for the identification and characterization of quercetin, kaempferol, ellagic acid and their derivatives in ethanolic extracts of Phyllanthus species. The chromatographic separation was carried out on Thermo Betasil C_8 column(250 mm×4.5 mm, 5 μm) using 0.1% formic acid in water and 0.1% formic acid in methanol as the mobile phase. The identification of diagnostic fragment ions and optimization of collision energies were carried out using 21 reference standards. Totally 51 compounds were identified which include 21 compounds identified and characterized unambiguously by comparison with their authentic standards and the remaining 30 were tentatively identified and characterized in ethanolic extracts of P. emblica, P. fraternus, P. amarus and ***.

关键词： Phyllanthus species HPLC-ESI-QTOF-MS/MS Phenolics

Geo-environmental application of municipal solid waste incinerator ash stabilized with cement

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Journal of Rock Mechanics and Geotechnical Engineering 2017年第2期9卷 370-375页

作者： Davinder singh Arvind kumar Department of Civil Engineering Dr. B.R. Ambedkar National Institute of TechnologyJalandharPunjabIndia

The behavior of soluble salts contained in the municipal solid waste incinerator(MSWI) ash significantly affects the strength development and hardening reaction when stabilized with *** present study focuses on the compaction and strength behavior of mixed specimens of cement and MSWI ash.A series of indices such as unconfined compressive strength,split tensile strength,California bearing ratio(CBR) and pH value was *** to this,the specimens were cured for 7 d,14 d,and 28 *** test results depict that the maximum dry density(MDD) decreases and the optimum moisture content(OMC)increases with the addition of *** test results also reveal that the cement increases the strength of the mixed ***,the combination of MSWI ash and cement can be used as a lightweight filling material in different structures like embankment and road construction.

关键词： Municipal solid waste incinerator(MSWI) ash Cement Compaction Stabilization California bearing ratio(CBR) test Geotechnical properties

A review on the current research on microwave processing techniques applied to graphene-based supercapacitor electrodes:An emerging approach beyond conventional heating

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Journal of Energy Chemistry 2022年第11期31卷 252-282,I0008页

作者： Rajesh kumar Sumanta Sahoo Ednan Joanni Rajesh kumar singh Department of Mechanical Engineering Indian Institute of TechnologyKanpur 208016Uttar PradeshIndia School of Chemical Engineering Yeungnam UniversityGyeongsanGyeongbuk 38541Republic of Korea Centre for Information Technology Renato Archer(CTI) Campinas 13069-901Brazil School of Physical and Material Sciences Central University of Himachal Pradesh(CUHP)KangraDharamshala 176215HPIndia

The various methods for microwave processing of materials exhibit numerous advantages,such as short processing times,high yield,expanded reaction conditions,high reproducibility,and high purity of ***-assisted synthesis strategies have been widely adopted for the preparation of highperformance graphene-based materials for supercapacitor *** oxides,mixed metal oxides,metal hydroxides,layered double hydroxides,carbon nanotubes and conducting polymers are some of the main materials which have been added to graphene derivatives for advanced composite/hybrid *** review article first provides a brief introduction and an overview of microwave heating and its advantages for processing graphene-based electrode *** that,a systematic survey of recently published research on microwave irradiation-assisted processing is presented,focusing on:(i)transformation of graphite/graphite oxide into graphene/graphene oxide by exfoliation and reduction;(ii)formation of graphene derivatives in various liquid and gaseous media;(iii)modification of graphene derivatives with various metal oxides/hydroxides,carbon nanotubes,and conducting polymers for use in *** challenges and future perspectives for microwave-assisted processing of graphene-based materials for cutting-edge supercapacitor electrode applications are also summarized in the conclusion.

关键词： Microwave irradiation Graphene derivatives Reduction/Exfoliation Supercapacitor Energy