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Chinese Chemical Letters 2006年第9期17卷 1137-1140页

作者： rahul r.nagawade Devanand B.SHINDE Division of Medicinal Chemistry-New Drug Discovery Wockhardt Research Centre Aurangabad-431210 (M.S.) India Department of Chemical Technology Dr. Babasaheb Ambedkar Marathwada University Aurangabad-431004 (M.S.) India Department of Chemical Technology Dr. Babasaheb Ambedkar Marathwada University Aurangabad-431004 (M.S.) India

The tetrahydroquinoline moiety is a structural feature of many natural products. By using a domino reaction of aromatic amines and cyclic enol ethers catalyzed by zirconyl chloride in water, various tetrahydroquinoline derivatives were synthesized efficiently. Most cyclized products showed cis selectivity. The cis selectivity was tentatively rationalized due to chelation control in water.

关键词： Anilines cyclic enol ether domino reaction tetrahydroquinoline zirconyl chloride

BF_3·OEt_2 Promoted Solvent-free Synthesis of Benzimidazole Derivatives

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Chinese Chemical Letters 2006年第4期17卷 453-456页

作者： rahul r.nagawade Devanand B.SHINDE Division of Medicinal Chemistry-New Drug Discovery Wockhardt Research CentreAurangabad-431210 (M.S.)India Department of Chemical TechnologyDr.Babasaheb Ambedkar Marathwada UniversityAurangabad-431004 (M.S.)India Department of Chemical Technology Dr.Babasaheb Ambedkar Marathwada UniversityAurangabad-431004 (M.S.)India

Differently substituted benzimidazoles have been synthesized in very good yields in solvent-free conditions from o-phenylenediamine and aldehydes in the presence of BF3·OEt2 as a catalyst. The method is applicable to aromatic, unsaturated and aliphatic aldehydes and to substituted o-phenylenediamines without significant differences.

关键词： BF3·OEt2 aldehydes benzimidazoles solvent-free reactions drugs.

Diabetic peripheral neuropathy and neuromodulation techniques:a systematic review of progress and prospects

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Neural regeneration research 2025年第8期20卷 2218-2230页

作者： rahul Mittal Keelin McKenna Grant Keith Evan McKenna Joana r.N.Lemos Jeenu Mittal Khemraj Hirani Diabetes research Institute University of Miami Miller School of MedicineMiamiFLUSA Department of Otolaryngology University of Miami Miller School of MedicineMiamiFLUSA Herbert Wertheim College of Medicine Florida International UniversityMiamiFLUSA School of Medicine and Public Health University of WisconsinMadisonWIUSA

Neuromodulation for diabetic peripheral neuropathy represents a significant area of interest in the management of chronic pain associated with this *** peripheral neuropathy,a common complication of diabetes,is characterized by nerve damage due to high blood sugar levels that lead to symptoms,such as pain,tingling,and numbness,primarily in the hands and *** aim of this systematic review was to evaluate the efficacy of neuromodulatory techniques as potential therapeutic interventions for patients with diabetic peripheral neuropathy,while also examining recent developments in this *** investigation encompassed an array of neuromodulation methods,including frequency rhythmic electrical modulated systems,dorsal root ganglion stimulation,and spinal cord *** systematic review suggests that neuromodulatory techniques may be useful in the treatment of diabetic peripheral *** the advantages of these treatments will enable physicians and other healthcare providers to offer additional options for patients with symptoms refractory to standard pharmacologic *** these efforts,we may improve quality of life and increase functional capacity in patients suffering from complications related to diabetic neuropathy.

关键词： diabetes mellitus diabetic peripheral neuropathy neuromodulation neurostimulation therapy non-pharmacological treatment pain management

Sulphamic Acid （H2NSO3H）-Catalyzed Multicomponent reaction of β-Naphthol： An Expeditious Synthesis of Amidoalkyl Naphthols

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Chinese Journal of Chemistry 2007年第11期25卷 1710-1714页

作者： nagawade, rahul r. SHINDE, Devanand B. Department of Chemical Technology Dr. Babasaheb Ambedkar Marathwada University Aurangabad 431004 (Maharashtra) India

Sulphamic acid （H2NSO3H） was found to be an efficient catalyst for the multicomponent condensation reaction of β-naphthol, aromatic aldehydes and urea or amides to afford the corresponding α-amidoalkyl-β-naphthols in good yields. The remarkable features of this new procedure are high conversions, short reaction time, clean reaction profiles and simple experimental and work-up procedures.

关键词： sulphamic acid multicomponent reaction condensation β-naphthol aryl aldehyde urea

Covalent Bond Based Android Malware Detection Using Permission and System Call Pairs

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Computers, Materials & Continua 2024年第3期78卷 4283-4301页

作者： rahul Gupta Kapil Sharma r.K.Garg Department of Information Technology Delhi Technological UniversityNew Delhi110042India Department of Mechanical Engineering Deenbandhu Chhotu Ram University of Science and TechnologyMurthal131039India

The prevalence of smartphones is deeply embedded in modern society,impacting various aspects of our *** versatility and functionalities have fundamentally changed how we communicate,work,seek entertainment,and access *** the many smartphones available,those operating on the Android platform dominate,being the most widely used *** widespread adoption of the Android OS has significantly contributed to increased malware attacks targeting the Android ecosystem in recent ***,there is an urgent need to develop new methods for detecting Android *** literature contains numerous works related to Android malware *** far as our understanding extends,we are the first ones to identify dangerous combinations of permissions and system calls to uncover malicious behavior in Android *** introduce a novel methodology that pairs permissions and system calls to distinguish between benign and malicious *** approach combines the advantages of static and dynamic analysis,offering a more comprehensive understanding of an application’s *** establish covalent bonds between permissions and system calls to assess their combined *** introduce a novel technique to determine these pairs’Covalent Bond Strength *** pair is assigned two scores,one for malicious behavior and another for benign *** scores serve as the basis for classifying applications as benign or *** correlating permissions with system calls,the study enables a detailed examination of how an app utilizes its requested permissions,aiding in differentiating legitimate and potentially harmful *** comprehensive analysis provides a robust framework for Android malware detection,marking a significant contribution to the *** results of our experiments demonstrate a remarkable overall accuracy of 97.5%,surpassing various state-of-the-art detection techniques proposed in the current literature.

关键词： Android malware android security hybrid analysis permission and system call pairs

Development of a drill energy utilization index for aiding selection of drill machines in surface mines

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International Journal of Mining Science and Technology 2017年第3期27卷 393-399页

作者： Kumar Suraj rahul Talreja Murthy V.M.S.r. Department of Mining Engineering Indian School of Mines Dhanbad India

Drill machines used in surface mines, particularly in coal, is characterized by a very poor utilization （around 40%） and low availability （around 60%）. The main purpose of this study is to develop a drill selec- tion methodology and simultaneously a performance evaluation technique based on drill cuttings produced and drilling rate achieved. In all 28 blast drilled through were investigated. The drilling was accomplished by 5 different drill machines of Ingersoll-rand and revathi working in coal mines of Sonepur Bazari （SECL） and Block-II （BCCL）. The drills are rotary and rotary Percussive type using tri- cone rock roller bits. Drill cuttings were collected and sieve analysis was done in the laboratory. Using rosin ramler Diagram, coarseness index （CI）, mean chip size （d）, specific-st trace area （SSA） and charac- teristic particle size distribution curves for all the holes drilled were plotted. The predictor equation for drill penetration rate established through multiple regressions was found to have a very good correlation with an index of determination of 0.85. A comparative analysis of particle size distribution curves was used to evaluate the drill efficiency. The suggested approach utilises the area under the curve, after the point of trend reversal and brittleness ratio of the respective bench to arrive at drill energy utilization index （DEUI）, for mapping of drill machine to bench, The developed DEU1 can aid in selecting or mapping a right machine to right bench for achieving higher penetration rate and utilizations.

关键词： Drill cutting parameter Coarseness index Mean chip size Specific surface area Particle size distribution curves Drill energy ptilization index

DIC Based Strain and Damage Analysis of Large Scale Steel to Composite Adhesive Joints Subjected to Tension and Compression Loading

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China Ocean Engineering 2023年第4期37卷 588-597页

作者： Pankaj r.JAISWAL rahul Iyer KUMAr richard TrUMPEr Wim DE WAELE Soete Laboratory Department of ElectromechanicalSystems and Metal Engineering(EMSME)Ghent UniversityGhent 9052Belgium BAE systems London SW1Y 5ADUnited Kingdom

This paper reports an experimental study of the mechanical response to tensile and compressive force of large scale steel to composite joints adhesively bonded with a thin layer of vinylester *** one specimen,the length of the reinforcing fibres in contact with the steel substrate has been reduced by saw cutting at both ends of the *** damaged specimen and four intact specimens were subjected to quasi-static tensile testing;six specimens were used for compression *** strain distribution at the composite surface and at the steel to hardwood connection of the specimen was monitored by digital image correlation(DIC).DIC allowed identifying the onset of damage in the tensile tested joints near the interface of the composite layer and the steel-hardwood *** tensile and compression tested specimens failed due to significant peel strain concentration at the composite near the connection of steel and *** average strength of a specimen tested in compression was about 66%higher than the average strength of a specimen tested in *** strain concentration zone in the damaged specimen was away from the introduced saw *** a result the damaged and intact tensile specimens showed the same failure strength and *** specimens failed by adhesive failure between the composite-hardwood interface.

关键词： vinylester resin multi-material joint strain damage digital image correlation.

Automatic area estimation of algal blooms in water bodies from UAV images using texture analysis

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Water Science and Engineering 2024年第1期17卷 62-71页

作者： Ajmeria rahul Gundu Lokesh Siddhartha Goswami r.N.Ponnalagu radhika Sudha Department of Electrical and Electronics Engineering Birla Institute of Technology&SciencePilani Hyderabad CampusTelangana 500078India

Algal blooms,the spread of algae on the surface of water bodies,have adverse effects not only on aquatic ecosystems but also on human *** adverse effects of harmful algal blooms(HABs)necessitate a convenient solution for detection and *** aerial vehicles(UAVs)have recently emerged as a tool for algal bloom detection,efficiently providing on-demand images at high spatiotemporal *** study developed an image processing method for algal bloom area estimation from the aerial images(obtained from the internet)captured using *** a remote sensing method of HAB detection,analysis,and monitoring,a combination of histogram and texture analyses was used to efficiently estimate the area of *** features like entropy(using the Kullback-Leibler method)were emphasized with the aid of a gray-level co-occurrence *** results showed that the orthogonal images demonstrated fewer errors,and the morphological filter best detected algal blooms in real time,with a precision of 80%.This study provided efficient image processing approaches using on-board UAVs for HAB monitoring.

关键词： Algal bloom Image processing Texture analysis Histogram analysis Unmanned aerial vehicles

Coagulation abnormalities and their relationship with bleeding manifestations in patients with dengue-A single center observational study

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Asian Pacific Journal of Tropical Medicine 2023年第2期16卷 65-71页

作者： Govind r.Patel Indu Thanvi Mohammad Nadeem rahul Kanwaria Department of Clinical Hematology Dr.SN Medical CollegeJodhpurRajasthanIndia Department of General Medicine Dr.SN Medical CollegeJodhpurRajasthanIndia

Objective:To evaluate coagulation abnormalities and their relationship with bleeding manifestations among patients with ***:This observational study was conducted on 292 adult dengue patients who were admitted to a tertiary care hospital of Western India from July 2021 to June *** tests including prothrombin time(PT),international normalized ratio(INr),activated partial thromboplastin time(aPTT),fibrinogen,and D-dimer were *** were monitored for bleeding ***:Coagulation abnormalities were reported in 42.8%of the ***,prolonged aPTT was the most common coagulation abnormality(40.8%),followed by low fibrinogen(38.7%),raised D-dimer(31.2%),raised INr(26.0%)and prolonged PT(19.2%).Bleeding manifestations were present in 19.9%***,INr,aPTT and D-dimer levels were significantly higher(Prinogen level was significantly lower(Pred to patients without *** with bleeding had a significantly higher rate of all coagulation abnormalities than patients without bleeding(Pr frequency of coagulation abnormalities compared to patients without *** with dengue should be assessed for coagulation abnormalities.

关键词： Dengue Coagulation abnormalities Coagulation parameters Prothrombin time Activated partial thromboplastin time Bleeding manifestations

Piezoelectric material selection for transducers under fuzzy environment

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Journal of Advanced Ceramics 2013年第2期2卷 141-148页

作者： Gaurav VATS rahul VAISH School of Engineering Indian Institute of Technology MandiHimachal Pradesh 175001India

Piezoelectric ceramics are extensively investigated materials for transducer *** selection of optimal piezoelectric material for this particular application is a tedious *** depends upon various physical properties,including piezoelectric charge coefficient(d33),electromechanical coupling factor(K_(p)),dielectric constant(ε_(r)),and dielectric loss(tanδ).The classical multiple attribute decision making(MADM)can be used for decision making if these properties are known ***,these properties cannot be expressed by exact numerical values,since they are dependent upon the microstructure and fabrication ***-based MADM approaches can be helpful in such *** this paper,we have determined the ranks and rank indices(for degree of closeness)of important piezoelectric materials using fuzzy VlseKriterijumska Optimisacija I Kompromisno resenje(VIKOr)***(8/65/35)((Pb_(1-x)La_(x))(Zr_(y)Ti_(1-y))O_(3))and KNN-LT-LS((K_(0.44)Na_(0.52)Li_(0.04))-(Nb0_(.84)Ta_(0.10)Sb_(0.06))O_(3))consecutively are found to be the top-rank piezoelectric *** indicates that KNN-LT-LS can be used on behalf of lead-based piezo-ceramics.

关键词： piezoceramics selection MADM fuzzy approach transducer application