Efficient cellular fusion of mononuclear precursors is the prerequisite for the generation of fully functional multinucleated bone-resorbing ***,the exact molecular factors and mechanisms controlling osteoclast fusion...
详细信息
Efficient cellular fusion of mononuclear precursors is the prerequisite for the generation of fully functional multinucleated bone-resorbing ***,the exact molecular factors and mechanisms controlling osteoclast fusion remain incompletely *** we identify RANKl-mediated activation of caspase-8 as early key event during osteoclast fusion.
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