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Cholecystoenteric fistula with and without gallstone ileus: A case series

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Hepatobiliary & Pancreatic Diseases International 2020年第1期19卷 36-40页

作者： Mauricio Gonzalez-Urquijo Mario rodarte-Shade Gerardo lozano-Balderas Gerardo Gil-Galind Tecnologico de Monterrey Escuela de MedicinaCiencias de la SaludDr.Ignacio Morones Prieto O 3000Monterrey 64710México Department of Surgery Hospital Metropolitano“Dr.Bernardo Sepúlveda”Secretaria de Salud de Nuevo LeónAdolfo López Mateos No.4600San Nicolás de los Garza 66400México

Background: A cholecystoenteric stula (CEF) is an uncommon complication of gallstone disease. The aim of this study was to present our experience of a series of patients with CEF, presenting with or without gallstone ileus, along with their surgical outcomes. Methods: From 2015 to 2018, 3245 consecutive patients underwent cholecystectomy for gallbladder disease at our institution, of which 15 were diagnosed with a CEF. All electronic medical records were retrospectively reviewed. Results: Fifteen patients presented with CEF. Ten patients presented cholecystoduodenal stula, four pa- tients cholecystocolonic, and one patient cholecystogastric counterparts. Twelve patients were female. The median patient age was 61 years (range 33 86 years). Five patients presented with gallstone ileus treated by laparotomy and enterolithotomy. In ten patients, a laparoscopic approach was attempted, but conversion to open surgery was necessary for eight of them. The median operative time was 140 min (range 60 240 min), and the median operative blood loss was 50 ml (range 10600ml). The procedure-related morbidity and mortality rates were 13.3% and 6.7%, respectively. Conclusions: There is no consensus on the best treatment modality for a CEF, as the treatment outcome is mostly dependent on the surgeon’s expertise and the patient’s condition. Not all CEFs are accompanied by gallstone ileus. For such case, the main purpose is to resolve the intestinal obstruction and, unless necessary, avoidance of the gallbladder area.

关键词： Cholecystoenteric stula Gallbladder disease Biliary-enteric stula Gallstone ileus Intestinal obstruction

Social Media Use and Empathy: A Mini Meta-Analysis

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Social Networking 2019年第4期8卷 147-157页

作者： Shu-Sha Angie Guan Sophia Hain Jennifer Cabrera Andrea rodarte California State University Northridge USA University of Illinois at Urbana-Champaign Champaign USA University of California Irvine USA

Concerns about the effects of social media or social networking site (SNS) use on prosocial development are increasing. The aim of the current study is to meta-analytically summarize the research to date (k = 5) about the relationship between general SNS use and two components of empathy (i.e., empathic concern and perspective-taking). random effects meta-analyses showed that SNS use was significantly and positively related to affective empathy though only marginally related to cognitive empathy. These effects were generally small in size and do not establish causality. Future research should explore how specific behaviors are related to different forms of empathy.

关键词： Social Media Empathic Concern Perspective-Taking

Association of CYP2C19 genotype with type 2 diabetes

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Health 2010年第10期2卷 1184-1190页

作者： Carlos Hoyo-Vadillo Jaime Garcia-Mena Adán Valladares Caterina R. Venturelli Niels Wacher-rodarte Jesús Kumate Miguel Cruz 不详

Background: CYP2C19 is a major isoform of cytochrome P450 that metabolizes a number of commonly prescribed drugs such as omeprazole, diazepam, tolbutamide and propranolol. Its expression is regulated by the constitutive androstane receptor (CAR), involved in glucocorticoids synthesis. Since a number of crossliniks have been described for CYPs and some hormones, an association of CYP2C19 with type 2 diabetes is likely. Methods: Two groups were studied, 352 diagnosed with type 2 diabetes patients and 342 healthy volunteers form Mexico City. Both groups were tested for CYP2C19*2 and *3 alleles. We carried out an allelic discrimination using TaqMan assay for *2, and used FRET sensor and anchor probes for *3. Results: Ninety one percent of the subjects had the wild type allele, 9% have the *2 allele;no subject presented the *3 allele. The CYP2C19*2 allele is associated with type 2 diabetes (p = 0.012). Admixmap program was used to correct the admixture of this population and get the correlation. This was further confirmed in a linear model with a 67% power and by the method of Strom and Wienker for association on subjects within the mean range of Amerindian ancestry only (60%). Conclusion: Type 2 diabetes patients have significatly more *2 allele than healthy volunteers, more evident for the patients with the homocygous genotype.

关键词： Pharmacogenomics CYP2C19 Type 2 Diabetes Mexicans Allele Frequency

Social Media Use and Empathy: A Mini Meta-Analysis

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Association of CYP2C19 genotype with type 2 diabetes

Social Networking（社交网络） 2019年第4期

作者： Shu-Sha Angie Guan Sophia Hain Jennifer Cabrera Andrea rodarte

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表面多孔圆柱状种植体与表面粗糙螺纹种植体的体内成骨和体外变形链球菌粘附研究

Health（健康） 2010年第10期

作者： Carlos Hoyo-Vadillo Jaime Garcia-Mena Adán Valladares Caterina R. Venturelli Niels Wacher-rodarte Jesús Kumate Miguel Cruz

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中国口腔医学继续教育杂志 2018年第5期21卷 279-285页

作者： Renata Falchete do Prado luis Gustavo Oliveira de Vasconcellos luana Marotta Reis de Vasconcellos Carlos Alberto Alves Cairo Daniel de Oliveira leite Alessandra dos Santos Antonio Olavo Cardoso Jorge Rogorio de lima Romeiro Ivan Balducci Yasmin rodarte Carvalho 李佳润(译) 滕伟(审) 不详中山大学光华口腔医学院·附属口腔医院修复科·广东省口腔医学重点实验室 510055

目的:分析和比较市售的粗糙表面螺纹种植体与多孔圆柱种植体在兔模型愈合的不同时期骨沉积情况。此外,研究种植体表面形态对变形链球菌粘附的影响。材料与方法:采用粉末冶金技术的新方法,制备有致密核心和多孔表面的钛种植体.以增加种... 详细信息

目的:分析和比较市售的粗糙表面螺纹种植体与多孔圆柱种植体在兔模型愈合的不同时期骨沉积情况。此外,研究种植体表面形态对变形链球菌粘附的影响。材料与方法:采用粉末冶金技术的新方法,制备有致密核心和多孔表面的钛种植体.以增加种植体骨结合率(BIC)。15只兔中,植入60个种植体。在每只兔子右、左侧胫骨各植入两个实验组和对照组种植体。实验组采用敲击就位,对照组自螺纹就位。术后4周、8周和12周处死动物.脱钙处理,检测种植体骨接触率。此外.在16个种植体(8个实验组,8个对照组)表面培养变形链球菌,评价细菌粘附情况。分别进行方差分析和t检验。结果:两组组织学均显示种植体-骨界面紧密接触.无软组织介入。多孔圆柱型种植体BIC(72.41%±9.47%)高于粗糙螺旋种植体(61.23%±14.12%)(P=O.013).而变形链球菌粘附情况无显著差异(P=O.351)。愈合4周时,两组间差距更明显(P=O.029)。两组间BIC在整个实验周期无显著性差异(P=O.333),但BIC随时间延长而提高。结论:在本研究条件.结果显示:新型种植体增加了BIC,且未增加变形链球菌粘附。

关键词：变形链球菌种植体骨细菌粘附体内成骨多孔螺纹表面粗糙种植体-骨界面