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THEOrETICAL ANALYSIS FOr THE MOTION AND TEMPErATUrE OF MELT DrOPLETS IN SPrAY DEgASSINg PrOCESS

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Acta Metallurgica Sinica(English Letters) 2007年第3期20卷 193-198页

作者： r.z. Wu z.K. Qu B.D. Sun D. Shu J. wa.g College of Materials Science ＆ Chemical Engineering Harbin Engineering University Harbin 150001 China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong University Shanghai 200030 China Department of Chemistry Harbin Normal University Harbin 150025 China

The motion of melt droplets in spray degassing process was analyzed theoretically. The height of the treatment tank in spray degassing process couM be determined by the results of theoretical calculation of motion of melt droplets. To know whether the melt droplets wouM solidify during spraying process, the balance temperature of melt droplets was also theoretically analyzed. Then proof experiments for theoretical results about temperature of melt droplets were carried. In comparison, the experimental results were nearly similar to the calculation results,

关键词： spray degassing hydrogen removal aluminum melt motion temperature

Targeting epigenetic mechanisms in amyloid-β-mediated Alzheimer’s pathophysiology:unveiling therapeutic potential

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Neural regeneration research 2025年第1期20卷 54-66页

作者： Jennie z.Li Nagendran ramalingam Shaomin Li Ann romney Center for Neurologic Diseases Brigham and Women’s Hospital and Harvard Medical SchoolBostonMAUSA

Alzheimer’s disease is a prominent chronic neurodegenerative condition character.z.d by a gradual decline in memory leading to *** evidence suggests that Alzheimer’s disease is associated with accumulating various amyloid-βoligomers in the brain,influenced by complex genetic and environmental *** memory and cognitive deficits observed during the prodromal and mild cognitive impairment phases of Alzheimer’s disease are believed to primarily result from synaptic *** life,environmental factors can lead to enduring changes in gene expression and the emergence of brain *** changes,known as epigenetic modifications,also play a crucial role in regulating the formation of synapses and their adaptability in response to neuronal *** this context,we highlight recent advances in understanding the roles played by key components of the epigenetic machinery,specifically DNA methylation,histone modification,and microrNAs,in the development of Alzheimer’s disease,synaptic function,and activity-dependent synaptic ***,we explore various strategies,including enriched environments,exposure to non-invasive brain stimulation,and the use of pharmacological agents,aimed at improving synaptic function and enhancing long-term potentiation,a process integral to epigenetic ***,we deliberate on the development of effective epigenetic agents and safe therapeutic approaches for managing Alzheimer’s *** suggest that addressing Alzheimer’s disease may require distinct tailored epigenetic drugs targeting different disease stages or pathways rather than relying on a single drug.

关键词： Alzheimer’s disease DNA methylation enriched environments histone modification microrNAs non-invasive brain stimulation synaptic plasticity

Polyethylene glycol fusion repair of severed rat sciatic nerves reestablishes axonal continuity and reorganizes sensory terminal fields in the spinal cord

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Neural regeneration research 2025年第7期20卷 2095-2107页

作者： Emily A.Hibbard Liwen zhou Cathy z.Yang Karthik Venkudusamy Yessenia Montoya Alexa Olivar.z.george D.Bittner Dale r.Sengelaub Program in Neuroscience Indiana UniversityBloomingtonINUSA Department of Neuroscience University of Texas at AustinAustinTXUSA

Peripheral nerve injuries result in the rapid degeneration of distal nerve segments and immediate loss of motor and sensory functions;behavioral recovery is typically *** used a plasmalemmal fusogen,polyethylene glycol(PEg),to immediately fuse closely apposed open ends of severed proximal and distal axons in rat sciatic *** have previously reported that sciatic nerve axons repaired by PEg-fusion do not undergo wallerian degeneration,and PEg-fused animals exhibit rapid(within 2–6 weeks)and extensive locomotor ***,our previous report showed that PEg-fusion of severed sciatic motor axons was non-specific,i.e.,spinal motoneurons in PEg-fused animals were found to project to appropriate as well as inappropriate target *** this study,we examined the consequences of PEg-fusion for sensory axons of the sciatic *** adult male and female rats(Sprague–Dawley)received either a unilateral single cut or ablation injury to the sciatic nerve and subsequent repair with or without(Negative Control)the application of *** action potentials recorded immediately after PEg-fusion repair confirmed conduction across the injury *** success of PEg-fusion was confirmed through Sciatic Functional Index testing with PEg-fused animals showing improvement in locomotor function beginning at 35 days *** 2–42 days postoperatively,we anterogradely labeled sensory afferents from the dorsal aspect of the hindpaw following bilateral intradermal injection of wheat germ agglutinin conjugated horseradish ***-fusion repair reestablished axonal *** to unoperated animals,labeled sensory afferents ipsilateral to the injury in PEg-fused animals were found in the appropriate area of the dorsal horn,as well as inappropriate mediolateral and rostrocaudal ***,despite having intact peripheral nerves,similar reorganizations of labeled sensory afferents were also observed contralateral to the injury and repa

关键词： axotomy dorsal horn peripheral nerve injury plasticity polyethylene glycol(PEg) sciatic nerve sensory terminals wheat germ agglutinin horseradish peroxidase

r & D OF CAST SUPErALLOYS AND PrOCESSINg FOr gAS TUrBINE BLADES IN BIAM

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Acta Metallurgica Sinica(English Letters) 1996年第6期9卷 457-463页

作者： Y.F. Han and r.z. Chen(Institute of Aeronautical Materials, Beijing 100095,China ) Beijing Inst of Aeronautical Materials Beijing China

research and development of cast superalloys and processing for turbine blades in BIAM during the last 35 years have been reviewed briefly in this paper.

关键词： cast nickel base superalloy turbine blade ceramic core shell Mold

Exotic states with QQQ′Q′configuration

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Communications in Theoretical Physics 2023年第3期75卷 56-61页

作者： z Asadi g r Boroun Department of Physics Razi UniversityKermanshah 67149Iran

In the framework of a non-relativistic quark model,we have calculated the masses of the QQQ′Q′(Q=c,b,s and Q′=c,b,s)tetraquark *** the linear and quadratic confinement potentials inside a Cornell-type potential along with all possible spin and color configurations,the Schrodinger equation masses of these tetraquark states have been *** on our numerical analysis,linear confinement and quadratic confinement produce acceptable *** that use linear confinement estimate charmonium-like tetraquark mass close to experimental data,as well as bottomonium-like tetraquark mass below the threshold of their meson-meson channels.

关键词： tetraquark quark model non-relativistic charmonium-like bottomonium-like

Polyethylene glycol fusion repair of severed sciatic nerves accelerates recovery of nociceptive sensory perceptions in male and female rats of different strains

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Neural regeneration research 2025年第9期20卷 2667-2681页

作者： Liwen zhou Karthik Venkudusamy Emily A.Hibbard Yessenia Montoya Alexa Olivar.z.Cathy z.Yang Adelaide Leung Varun gokhale guhan Periyasamy zeal Pathak Dale r.Sengelaub george D.Bittner Department of Neuroscience University of TexasAustinTXUSA Program in Neuroscience Indiana UniversityBloomingtonINUSA Department of Molecular Biosciences University of TexasAustinTXUSA

Successful polyethylene glycol fusion(PEg-fusion)of severed axons following peripheral nerve injuries for PEg-fused axons has been reported to:(1)rapidly restore electrophysiological continuity;(2)prevent distal wallerian Degeneration and maintain their myelin sheaths;(3)promote primarily motor,voluntary behavioral recoveries as assessed by the Sciatic Functional Index;and,(4)rapidly produce correct and incorrect connections in many possible combinations that produce rapid and extensive recovery of functional peripheral nervous system/central nervous system connections and reflex(e.g.,toe twitch)or voluntary *** preceding companion paper describes sensory terminal field reo rganization following PEg-fusion repair of sciatic nerve transections or ablations;howeve r,sensory behavioral recovery has not been explicitly explored following PEg-fusion *** the current study,we confirmed the success of PEg-fusion surgeries according to criteria(1-3)above and more extensively investigated whether PEg-fusion enhanced mechanical nociceptive recovery following sciatic transection in male and female outbred Sprague-Dawley and inbred Lewis *** nociceptive responses were assessed by measuring withdrawal thresholds using von Frey filaments on the dorsal and midplantar regions of the *** von Frey filament tests were a more reliable method than plantar von Frey filament tests to assess mechanical nociceptive sensitivity following sciatic nerve *** withdrawal thresholds of the sciatic-mediated lateral dorsal region differed significantly across strain but not *** thresholds did not change significantly from baseline in chronic Unoperated and Sham-operated *** sciatic transection,all rats exhibited severe hyposensitivity to stimuli at the lateral dorsal region of the hindpaw ipsilateral to the ***,PEg-fused rats exhibited significantly earlier return to baseline withdrawal thresholds than Negative

关键词： autophagia axotomy collateral sprouting neuropathic pain peripheral nerve repair polyethylene glycol fusion(PEg-fusion) saphenous nerve sensory neurons sex and strain wallerian degeneration

Transport mechanism in chemically reactive hybrid nanofluid flow containing gyrotactic micro-organisms over a curved oscillatory surface

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 177-192页

作者： M.NAVEED M.IMrAN T.ASgHAr.z.ABBAS Department of Mathematics Division of Science and TechnologyUniversity of Education Department of Mathematics The Islamia University of Bahawalpur

This paper examines the transport analysis, including both heat transfer and mass transfer, in hybrid nanofluid flow containing gyrotactic microorganisms towards a curved oscillatory surface. The influence of magnetic fields is also inspected in terms of their physical characteristics. To depict the phenomena of transport, modified versions of both Fick's and Fourier's laws are used. Additionally, the characteristics of both heterogeneous and homogeneous chemical reactions are also incorporated. Utilizing a curvilinear coordinate system, the flow problem is formulated as partial differential equations(PDEs)for momentum, concentration, microorganism field, and energy. An analytical solution to the obtained flow equations is achieved utilizing the homotopy analysis method(HAM).The effects of significant flow parameters on the pressure and microorganism fields, velocity, oscillation velocity, concentration, and temperature distributions are shown via graphs. Furthermore, the variations in skin friction, mass transfer rate, heat transfer rate, and local motile number due to different involved parameters are presented in tables and are analyzed in detail. graphical results indicate that the curves of velocity and temperature fields are enhanced as the values of the solid volume fraction variables *** is also verified that the concentration rate field decreases as the values of the homogeneous reaction strength parameter and the radius of curvature parameter increase, and it increases with the Schmidt number and the heterogeneous reaction strength *** outcomes show a favorable response of the motile number to advanced values of the Peclet number, the Schmidt number, the microorganism difference parameter, and the bio-convective Lewis number.

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Dynamic Deformation of Fr.z.n Soil at a High Strain rate:Experiments and Damage-Coupled Constitutive Model

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Acta Mechanica Solida Sinica 2021年第6期34卷 895-910页

作者： z.W.zhu W.r.Tang g.z.Kang Applied Mechanics and Structural Safety Key Laboratory of Sichuan Province School of Mechanics and EngineeringSouthwest Jiaotong UniversityChengdu610036China Northwest institute of Eco-Environment and resources State Key Laboratory of Frozen Soil EngineeringChinese Academy of SciencesLanzhou730000China

The dynamic compressive deformation of fr.z.n soil was investigated by conducting the split-Hopkinson pressure bar(SHPB)experiments at three temperatures and different high strain rates,and the dynamic stress–strain responses and failure modes of the fr.z.n soil were *** experimental results demonstrate that the fr.z.n soil exhibits evident dependence on the strain rate and temperature under the dynamic loading *** dynamic compressive stress–strain curve of the fr.z.n soil was divided into three parts:the linear,nonlinear rising,and strain softening *** nonlinear rising and strain softening parts were both caused by the damage attributed to the debonding between the ice particles and soil matrix,from which a rate-dependent damage evolution equation was ***,a damage-coupled dynamic viscoelastic constitutive model of fr.z.n soil at high strain rate was derived.A comparison between the theoretically predicted results and the experimental ones showed that the developed dynamic viscoelastic model could well describe the dynamic mechanical behavior of fr.z.n soil at high strain rate.

关键词： Fr.z.n soil Dynamic compression High strain rate Damage Constitutive model

Universal function of the diffractive process in color dipole picture

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Chinese Physics C 2021年第2期45卷 111-118页

作者： z.Jalilian g.r.Boroun Department of Physics Razi UniversityKermanshah67149Iran

In this study,we obtain the universal function corresponding to the diffractive process and show that the cross section exhibits geometrical *** is observed that diffractive theory according to the color dipole approach at small-x is a convenient framework that reveals the color transparency and saturation *** also calculate the contribution of heavy quark production in the diffractive cross section at high energy that is determined by the small size dipole *** ratio of the diffractive cross section to the total cross section in electron-proton collision is the other important quantity that is computed in this work.

关键词： universal function structure function cross section color dipole model diffractive process