检索结果-南通市图书馆

r.c aggregation,deformation and adhesion to endothelium:role of nitr.c oxide derived from L-Arginine and sodium nitroprusside

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Innovative optical Health Sciences 2024年第5期17卷 53-65页

作者： M.K.Maksimov P.B.Ermolinskiy o.n.Scheglovitova n.n.Sklyankina A.V.Muravyov A.E.Lugovtsov A.V.Priezzhev Faculty of Physics M.V.Lomonosov Moscow State University bld.1subbuilding.2Leninskie goryMoscow 11991Russia n.F.gamaleya national research center for Epidemiology and Microbiology 18 Gamaleya StreetMoscow 123098Russia K.D.Ushinsky Yaroslavl State Pedagogical University 108/1 Respublikanskaya StreetYaroslavl 150000Russia

red blood cells(r.cs)are the most abundant human blood *** aggregation and deformation strongly determine blood viscosity which impacts hemorheology and *** turn,r.c properties depend on di®erent endogenous and exogenous *** such factor is nitr.c oxide(no),which is mainly produced by endothelial cells(Ec)from L-arginine amino acid in the circulatory *** the mechanisms of the r.c-endothelium interplay are not clear up to date and considering its possible clinical importance,the aims of this study are to investigate in vitro:(1)The e®ect of L-arginine induced no on r.c aggregation and adhesion to endothelium;(2)the no e®ect on r.c aggregation and deformation induced by L-arginine and sodium nitroprusside without the presence of endothelium in the *** r.c aggregation and adhesion to a monolayer of Ec were studied using optical tweezers(oT).The r.c deformability and aggregation without endothelium in the samples were studied using the°ow chamber method and Myrenne *** con¯rmed that no increases deformability and decreases aggregation of *** showed that the soluble guanylate cyclase pathway appears to be the only no signaling pathway *** the samples with the endothelium,the\bell-shaped"dependence of r.c aggregation force on L-arginine concentration was observed,which improves our knowledge about the pr.cess of no production by ***,data related to L-arginine accumulation by endothelium were obtained:necessity of the presence of extr.cellular L-arginine stated by other authors was put under *** our study,no decreased the r.c-endothelium adhesion,however,the tendency appeared to be weak and was not con¯rmed in another set of *** our knowledge,this is the¯rst attempt to measure the forces of r.c adhesion to endothelium monolayer with oT.

关键词： red blood cells aggregation L-arginine endothelium optical tweezers Myrenne flow chamber

In situ meso-tetra(4-carboxyphenyl)porphyrin ligand substitution in Hf-MoF for enhanced catalytic activity and stability in photoredox reactions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

rare Metals 2024年第6期43卷 2682-2694页

作者： Jie Hu Hong-Xin Lao Xiu-Wu Xu Wei-Kang Wang le-le Wang Qin-Qin Liu School of Materials Science and Engineering Jiangsu UniversityZhenjiang 212013China college of chemistry and Materials Engineering Research Center of Carbon NeutralityAnhui Normal UniversityWuhu 241002China Fujian Provincial Key Laboratory of Ecology-Toxicological Effects and control for Emerging contaminants Putian UniversityPutian 351100China

Though there are numerous intrinsic merits of metal-organic frameworks(MoFs),low charge separation efficiency has imposed heavy restr.ctions on their photocatalytic ***,in situ porphyrin ligand substitution,as a strategy for improving the charge separation efficiency and increasing the amounts of active sites,has been designed and realized in a Hf-biphenyl dicarboxylic acid(BPDc)***,a size and geometry matched meso-tetra(4-carboxyphenyl)porphyrin(TcPP)ligand was selected and doped into Hf-BPDc MoF by forming coordinating bonds with Hf centers,forming dualligand Hf-BPDc-TcPP *** resultant Hf-BPDc-TcPP MoF showed significantly improved activity and chemical stability in the photocatalytic H_(2)generation(261μmol·g^(-1)·h^(-1))and tetr.cycline(Tc)degradation reactions(95.8%),which was 48 and 1.47 folds higher than that of the Hf-BPDc *** and electr.chemical studies revealed that the introduction of porphyrin ligand could generate a stronger internal electr.c field for boosting the charge separation and transfer,increase the specific surface area for providing more active sites,and narrow the band gap to enhance the visible light *** in situ ligand substitution method provides a promising approach to build a tunable platform for.constr.cting high-performance MoF photocatalysts.

关键词： Ligand substitution Metal organic frameworks Meso-tetra(4-carboxyphenyl)porphyrin Hydrogen evolution reaction Tetr.cycline degradation

Study of Zno nanoparticle-supported clay minerals for electr.chemical sensors,photocatalysis,and antioxidant applications

在线全文

学校读者我要写书评

暂无评论

chemPhysMater 2024年第1期3卷 83-93页

作者： Mylarappa M n.raghavendra n.r.Bhumika c.H.chaithra B.n.nagalaxmi K.n.Shravana Kumara Department of chemistry Sri Jagadguru Renukacharya College of ScienceArts&CommerceBengaluru 560009India Department of chemistry East West Institute of TechnologyBengaluru 560091India Department of chemistry Maharani Lakshmi Ammanni College for WomenBengaluru 560012India

In view of the current study’s demonstration of the synthesis of clay-doped Zno composites,we present a low-cost method for producing clay-metal oxide(clay/Zno).Utilizing the solution combustion technique,a composite of clay/Zno was produced utilizing citr.c acid as both a fuel and a complexing *** hexagonal unit cell str.cture of the created clay/Zno may be seen using XrD *** Zno-infused clay was visible in FE-SEM micrographs as homogenous,sphere-shaped *** possible involvement of clay/Zno photocatalytic activity in the UV-induced photodegradation of malachite green dye was *** 90%degradation rate shows the composite’s outstanding photocatalytic degradation *** resulting substance was electr.chemically analyzed using a constr.cted electrode in 0.1 M KoH *** increased its sensor.capabilities,which now include chemical and biomolecule sensors,and it excelled in cyclic voltammetry-based redox potential *** efficiently evaluate chemically synthesized nPs for electr.chemical,sensing,and photocatalytic applications,this study intends to create a solution combustion pr.cedure for the synthesis of clay/Zno nanocomposite using urea as fuel.

关键词： clay clay/Zno Photocatalytic Electr.chemical sensors

rotating effects on the photoionization cross-section of a 2D quantum ring

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

communications in Theoretical Physics 2024年第10期76卷 153-159页

作者： carlos Magno o Pereira Frankbelson dos S Azevedo Luís Fernando c Pereira Edilberto o Silva Departamento de Física Universidade Federal do Maranh?o

In this article, we investigate the nonrelativistic quantum motion of a charged particle within a rotating frame, taking into account the Aharonov–Bohm(AB) effect and a uniform magnetic field. our analysis entails the derivation of the equation of motion and the corresponding radial equation to describe the system. Solving the resulting radial equation enables us to determine the eigenvalues and eigenfunctions, providing a clear expression for the energy levels. Furthermore,our numer.cal analysis highlights the substantial influence of rotation on both energy levels and optical properties. Specifically, we evaluate the photoionization cross-section with and without the effects of rotation. To elucidate the impact of rotation on the photoionization pr.cess of the system, we present graphics that offer an appealing visualization of the intrinsic nature of the physics involved.

关键词： Aharonov-Bohm effect photoionization cross-section quantum ring rotating effect

Fault Location Method for overhead Feeders with Distributed generation Units Based on Dir.ct Load Flow Approach

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Modern Power Systems and clean Energy 2024年第4期12卷 1135-1146页

作者： charalampos g.Arsoniadis Vassilis c.nikolaidis Department of Electr.cal and computer Engineering Democritus University of ThraceXanthi 67100Greece

This paper proposes a novel fault location method for overhead feeders,which is based on the dir.ct load flow *** method is developed in the phase domain to effec-tively deal with unbalanced network conditions,while it can al-so handle any type of distributed generation(Dg)units without requiring equivalent *** utilizing the line series parame-ters and synchronized or unsynchronized voltage and current phasor measurements taken from the sources,the method reli-ably identifies the most probable faulty *** the aid of an index,the exact faulty section among the multiple candi-dates is *** simulation studies for the IEEE 123-bus test feeder demonstrate that the proposed method accu-rately estimates the fault position under numerous short-circuit conditions with varying pre-fault system loading conditions,fault resistances,and measurement *** proposed meth-od is promising for pr.ctical applications due to the limited number of required measurement devices as well as the short computation time.

关键词： Fault location distribution system dir.ct load flow distributed generation

Beyond wr.cking a wall:revisiting the concept of blood–brain barrier breakdown in ischemic stroke

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

neural regeneration research 2025年第7期20卷 1944-1956页

作者： Julia castillo-g.nzález Elena g.nzález-rey Institute of Parasitology and Biomedicine Lopez-neyra(IPBLn) CSICPT SaludGranadaSpain

The blood–brain barrier.constitutes a dynamic and inter.ctive boundary separating the central nervous system and the peripheral *** tightly modulates the ion transport and nutrient influx,while restr.cting the entry of harmful factors,and selectively limiting the migration of immune cells,thereby maintaining brain *** the well-established association between blood–brain barrier disruption and most neurodegenerative/neuroinflammatory diseases,much remains unknown about the factors influencing its physiology and the mechanisms underlying its ***,the role of blood–brain barrier breakdown in the translational failure underlying therapies for brain disorders is just starting to be *** review aims to revisit this concept of“blood–brain barrier breakdown,”delving into the most controversial aspects,prevalent challenges,and knowledge gaps concerning the lack of blood–brain barrier *** moving beyond the oversimplistic dichotomy of an“open”/“bad”or a“closed”/“good”barrier,our objective is to provide a more comprehensive insight into blood–brain barrier dynamics,to identify novel targets and/or therapeutic approaches aimed at mitigating blood–brain barrier ***,in this review,we advocate for.considering the diverse time-and location-dependent alterations in the blood–brain barrier,which go beyond tight-junction disruption or brain endothelial cell breakdown,illustrated through the dynamics of ischemic stroke as a case *** this exploration,we seek to under.core the complexity of blood–brain barrier dysfunction and its implications for the pathogenesis and therapy of brain diseases.

关键词： blood–brain barrier disruption drug delivery ischemic stroke neuroinflammation tight-junctions

A discussion of fatigue properties of notched specimens subjected to prestressing treatment machined from FgH4097

在线全文

学校读者我要写书评

暂无评论

chinese Journal of Aeronautics 2024年第4期37卷 508-523页

作者： rongxi SHI Dasheng WEI le HAn Shun YAng School of Energy and Power Engineering Beihang UniversityBeijing 100191China Jiangxi research Institute Beihang UniversityNanchang 330096China research Institute of Aero-Engine Beihang UniversityBeijing 100191China

Experimental and numer.cal investigations were performed to reveal the effect of prestress on the fatigue properties of FgH4097 so as to quantitatively evaluate the overspeed benefit of the disc of aeroengine. A corresponding experiment was performed to examine the effect of prestress on the fatigue life of FgH97. A complete model describing the fatigue properties of the prestressed notch specimen was proposed. After the modification of mean stress, stress gradient and prestressing treatment, the model is finally verified by fatigue test of presstressed notch specimens machined from FgH4097 with satisfactory accur.cy and good engineering applicability. The new model highlights that for the variable fatigue loads, the introduction of appropriate prestress is expected to benefit to the notch specimens and certainly to the disc of aeroengine regards of their fatigue properties. Both the calculation method of fatigue life parameters and the prestress corr.ction model are proved to have good prediction accur.cy.

关键词： Turbine blisk overspeed test Prestress Fatigue life prediction FgH4097

Heat Transfer and Flow Str.cture of a Turbine Blade's Air.cooled leading Edge considering Different Hole Shapes and Additional Flow Angles

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2024年第4期33卷 1421-1442页

作者： QIn runxuan ZHoU Xun WAng Songtao cAI le School of Energy Science and Engineering Harbin Institute of TechnologyHarbin150001China

A numer.cal study is conducted to elucidate the impact of hole shapes and additional flow angles on the flow str.cture of the coolant and temperature field in the leading edge area of the gas turbine *** typical hole shapes are considered for the gE-E3 *** impact of the additional flow angle(E)within each hole shape on the temperature field is *** results indicate that for the leading edge area and suction surface,the fan-shaped hole case performs best in decreasing temperatures,with a decrease of about 43 *** is mainly due to the fact that the fan-shaped hole has the maximum expansion in hole spanwise *** the pressure surface,the console hole case performs best in decreasing temperatures,with a maximum reduction of about 47.2 *** influence of E on the surface temperature at leading edge area varied between the different hole *** the cylinder hole and console hole,the E=-20°case has the lowest area-averaged *** both the fan-shaped hole and the 7-7-7 shaped hole are expansion holes,the pattern of variation of the leading edge area temperature with increasing E is similar for the fan-shaped hole case and 7-7-7 shaped hole *** E=20°case shows the lowest spanwise-averaged temperature near the hole outlet,and the E=-20°case shows the lowest spanwise-averaged temperature further downstream.

关键词： film cooling gE-E3 turbine rotor blade conjugate heat transfer leading edge

Design of a novel Exoskeleton with Passive Magnetic Spring Self-locking and Spine Lateral Balancing

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2024年第1期21卷 236-255页

作者： Jhon F.rodríguez-león Betsy D.M.chaparro-r.co Daniele cafolla Francesco Lago Eduardo castillo-castañeda giuseppe carbone centro de Investigacion en ciencia Aplicada y Tecnologia Avanzada Unidad Querétaro MecatronicaInstituto Politécnico NacionalCerro Blanco 14176090 Colinas del CimatarioQuerétaroMexico Department of Mechanical Energy and Management EngineeringUniversity of CalabriaVia P.Bucci Cubo 46 C87036 RendeItaly Faculty of Science and Engineering Department of Computer ScienceSwansea UniversitySwanseaUK cESTEr University of Cluj-NapocaCluj-NapocaRomania

This paper proposes a new upper-limb exoskeleton to reduce worker physical *** proposed design is based on a novel PrrrP(P-Prismatic;r-revolute)kinematic chain with 5 passive Degrees of Freedom(DoF).Utilizing a magnetic spring,the proposed mechanism includes a specially designed locking mechanism that maintains any desired task *** proposed exoskeleton incorporates a balancing mechanism to alleviate discomfort and spinal torsional effects also helping in limb weight *** paper reports specific models and simulations to demonstrate the feasibility and effectiveness of the proposed *** experimental char.cterization is performed to validate the performance of the mechanism in terms of forces and physical strain during a specific application consisting of ceiling-surface drilling *** obtained results preliminarily validate the engineering feasibility and effectiveness of the proposed exoskeleton in the intended operation task thereby requiring the user to exert significantly less force than when not wearing it.

关键词： Assistive mechanism Exoskeleton Locking mechanism Bionic robot