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Utilization of Pyrrolic Compounds as Indicators of Secondary Migration for Woodford Oils in the Anadarko Basin,Oklahoma,USA

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Journal of Earth Science 2024年第5期35卷 1499-1512页

作者： Mu Liu r.paul Philp Key Laboratory of Cenozoic Geology and Environment Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China School of Geosciences University of OklahomaNorman 73109United States

Migration pathways and distances of the oils in reservoir are thought to affect the distribution of pyrrolic compounds such as carbazole,its alkyl derivatives(alkylated carbazoles)and benzocarbazoles,although other factors,including maturity and depositional environments may also affect the distribution of these organic nitrogen *** this study,14 oil samples produced from conventional reservoirs in pauls Valley,south Oklahoma were investigated using organic geochemical *** sterane and hopane fingerprints suggest that most of the oils were sourced from the Devonian Woodford *** parameters consistently indicate that the maturity level of the studied samples are all of similar maturity(rc=~0.7%),suggesting the distribution of the organic nitrogen organic compounds is possibly reflecting variations in relative migration *** distribution of alkylcarbazoles revealed a preferential enrichment during migration,with the nitrogen-shielded alkylcarbazole tending to be enriched relative to the nitrogen-semi-shielded alkylcarbozoles particularly in oils produced close to the Arbuckle uplift to the ***,another family of pyrrolic compounds,benzocarbazoles,whose distributions also indicated that the pauls Valley Woodford oils came from deeper part of the Anadarko Basin as the benzo-[a]/([a]+[c])-carbazole ratios decrease *** more specific migration systems,although the pyrrolic compound indicators are potentially disturbed by the structural complexes,the general migration directions suggest that the studied oils in pauls Valley Hunton uplift were sourced from the deep basin area,and migrate upwards in porous sediments due to the *** study investigates the feasibility of using pyrrolic compounds to estimate relative migration distances and will aid in the interpretation of migration history by using the distribution of carbazole,alkylated carbazoles,benzocarbazoles isomers in the Anadarko and Ardmore Basin

关键词： carbazole migration oil Oklahoma biomarker organic geochemistry

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Using true‑triaxial stress path to simulate excavation‑induced rock damage:a case study

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International Journal of Coal Science & Technology 2022年第4期9卷 165-180页

作者： Qingsheng Bai Cun Zhang r.paul Young State Key Laboratory of Coal Mine Disaster Dynamics and Control Chongqing UniversityChongqing 400044China Geotechnical Institute TU Bergakademie FreibergGustav-Zeuner-Straße 109599 FreibergGermany School of resource and Safety Engineering China University of Mining and Technology(Beijing)BeijingChina Department of Civil and Mineral Engineering University of TorontoTorontoCanada

This study presents an example illustrating the role of in situ 3D stress path method in simulating the roof damage development observed in the Mine-by tunnel at Underground research Laboratory(UrL)located in Manitoba,*** 3D stress path,at the point 1 cm in the crown of the Mine-by tunnel,was applied to a cubic Lac du Bonnet(LdB)granite sample to further understand the roof damage process and the associated *** careful calibrations,a numerical model was used to reproduce the experiment,which produced similar seismicity processes and source *** emission(AE)events obtained from laboratory and numerical modeling were converted to locations in relation to the tunnel face and were compared to the feld microseismicity(MS)occurring in the upper notch region of the Mine-by *** crack development and damage mechanism are carefully *** diference between tests and feld monitoring was *** intermediate principal stress(σ_(2))unloading process was carried out in numerical simulation to investigate its role in rock damage *** results clearly showedσ_(2)could play a signifcant role both in damage development and failure *** should be considered when predicting the damage region in underground *** study highlights the potential role of laboratory and numerical stress path tests to investigate fracture processes and mechanisms occurring during engineering activities such as tunnel excavation.

关键词： Acoustic emission Damage development In situ 3D stress path Numerical simulation True-triaxial experiment

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Unusual N-Alkane Distributions in Extracts from Marine Carbonate rocks at High Levels of Maturity and Overmaturity

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Chinese Journal Of Geochemistry 2002年第4期21卷 322-333页

作者：李景贵 r.paul PHILP 崔明中 State Key Laboratory of Gas Geochemistry Lanzhou Institute of Geology Chinese Academy of Sciences Lanzhou 730000 China School of Geology and Geophysics University of Oklahoma Norman OK. 73019 U. S. A

N\|alkanes in extracts from possible carbonate source rocks of the Lower Ordovician Majiagou Formation in the central gas field of the Shanganning Basin and the Upper Sinian Dengying Formation in the Weiyuan gas field of the Sichuan Basin, are characterized by bimodal distributions with the dominant carbon numbers in the range C\- 17 \|C\- 21 and C\- 25 \|C\- 29 . In most samples, the lower carbon number components are present in greater abundance than the higher carbon number ones. Most samples contain significant concentrations of waxy hydrocarbons(C\- 22+ ) with C\- 21- /C\- 22+ ratios between 0.50 to 3.16, and an average value of 1.34. The n\|alkanes in extracts of outcrops and shallow core samples of Upper Proterozoic and Lower Palaeozoic carbonate rocks in the western and southern parts of the North China Basin are of unimodal distributions dominated by n\|alkanes maximizing in the C\- 25 \|C\- 29 range. These extracts have very high concentrations of waxy hydrocarbons with C\- 21- /C\- 22+ ratios all ranging from 0 14 to 0 90 and averaging 0.36. All of the extracts have a marked odd/even predominance in the high molecular weight n\|alkane range regardless of whether they are from shallow or deep cores or outcrop samples. Simulation experiments were performed using typical sapropelic\|type kerogens from the immature Sinian Lower Xiamalin Formation carbonate\|rich shales collected at Jixian, Hebei Province, North China Basin, and the contemporary microplanktonic blue\|green algae Spirulina subsala. results indicate that the unusual distribution of n\|alkanes in the extracts of Upper Proterozoic and Lower Palaeozoic carbonate rocks possibly originated from algae in the source rocks at high levels of maturity and overmaturity.

关键词：海藻中国海相碳酸盐岩链烷双峰分面成熟期

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Phage-mediated horizontal gene transfer and its implications for the human gut microbiome

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Gastroenterology report 2022年第1期10卷 78-89页

作者： Tatiana Borodovich Andrey N.Shkoporov r.paul ross Colin Hill APC Microbiome Ireland University College CorkCorkIreland School of Microbiology University College CorkCorkIreland

Horizontal gene transfer(HGT)in the microbiome has profound consequences for human health and *** spread of antibiotic resistance genes,virulence,and pathogenicity determinants predominantly occurs by way of *** exists of extensive horizontal transfer in the human gut *** transduction is a type of HGT event in which a bacteriophage transfers non-viral DNA from one bacterial host cell to *** abundance of tailed bacteriophages in the human gut suggests that transduction could act as a significant mode of HGT in the gut *** we review in detail the known mechanisms of phage-mediated HGT,namely specialized and generalized transduction,lateral transduction,gene-transfer agents,and molecular piracy,as well as methods used to detect phage-mediated HGT,and discuss its potential implications for the human gut microbiome.

关键词： gut phageome horizontal gene transfer gene transduction phage-mediated gene transfer

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基于流量偏差率的滴灌毛管管径简易设计（英文）

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农业工程学报 2016年第5期32卷 14-20页

作者：鞠学良吴普特 Weckler r.paul 朱德兰张林西北农林科技大学水土保持研究所杨凌712100 西北农林科技大学中国旱区节水农业研究院杨凌712100 Department of Biosystems and Agricultural Engineering Oklahoma State University

满足灌水均匀度设计标准与额定流量的滴灌毛管管径优化设计是滴灌毛管水力设计的重要内容。该文以流量偏差率为灌水均匀度设计标准,提出一种简易的滴灌毛管管径水力设计方法。通过改变单向和双向滴灌毛管流量偏差率解析公式的形式,提出... 详细信息

满足灌水均匀度设计标准与额定流量的滴灌毛管管径优化设计是滴灌毛管水力设计的重要内容。该文以流量偏差率为灌水均匀度设计标准,提出一种简易的滴灌毛管管径水力设计方法。通过改变单向和双向滴灌毛管流量偏差率解析公式的形式,提出一个新的管径设计参数。基于能坡线法,建立参数与坡降比参数的关系,并绘制和构建相关图形和计算公式。结果表明：当流量指数分别取值为1.75、1.69和1.00时,单向毛管管径的设计参数取值分别为-1～≤2.801,-1～≤2.859和-1～≤4;双向毛管管径的设计参数取值分别为0～≤3.143,0～≤3.183和0～≤4。满足流量偏差率设计标准和灌水器额定流量时,单向毛管管径将有1或2个设计值,双向毛管管径将有1、2或多个设计值。根据参数的取值范围,以坡降比参数为设计变量,推导了均匀坡下单向和双向毛管管径的计算公式。此外,进一步简化了滴灌毛管进口工作水头的计算公式。当已知设计流量,流量偏差率设计标准,毛管管长等参数时,可以按照设计步骤直接计算滴灌毛管管径和进口工作水头,无需进行任何复杂的试算。设计案例1表明在多数地形条件下,利用该文方法设计单向毛管的结果与传统方法设计结果的相对误差不超过4%;设计案例2表明该文方法设计双向毛管的结果与其他2种常用方法设计结果的最大相对误差为4%。因此,从工程实践角度,利用该方法设计的滴灌毛管管径和进口工作水头与其他传统方法设计结果非常接近。相比于传统设计方法,该方法简便实用,可以直接应用于滴灌工程设计。该研究可为改进滴灌毛管优化设计提供理论依据。

关键词：灌溉滴头流速滴灌流量偏差率管径解析方法

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Bifidobacterium breve CCFM1078 regulates bone development in growing BALB/c mice via gut microbiota and metabolites to balance bone formation and resorption

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Food Science and Human Wellness 2024年

作者： Bowen Li Mengfan Ding Xiaoming Liu Haiqin Chen Jianxin Zhao r.paul ross Catherine Stanton Shilong Jiang Wei Chen Bo Yang State Key Laboratory of Food Science and Technology， Jiangnan University School of Food Science and Technology， Jiangnan University International Joint research Center for Probiotics & Gut Health， Jiangnan University APC Microbiome Ireland， University College Cork Teagasc Food research Centre Nutrition and Metabolism research Division， Innovation Center， Heilongjiang Feihe Dairy Co.， Ltd. PKUHSC-China Feihe Joint research Institute of Nutrition and Healthy Lifespan Development National Engineering research Center for Functional Food， Jiangnan University

This study endeavors to investigate the effects of Bifidobacterium breve CCFM1078 on bone formation and resorption balance in growing BALB/c mice. Newborn BALB/c mice were assigned to the control group (administration saline) and the CCFM1078 group (administration B. breve CCFM1078， 3 × 109CFU/day) in 3-， 4-， and 5-week tests. All the groups have male and female distinctions. Our findings demonstrate that B. breve CCFM1078 exerts on the dynamic equilibrium between bone formation and resorption during the critical period of growth in mice by modulating the composition of gut microbiota and metabolites (hexadecanamide， linoleoyl ethanolamide， and palmitoyl ethanolamide)， the genes and proteins expression related to the GH/IGF-1 axis and Gs/PKA/CrEB signaling pathways， as well as downstream osteogenic and osteoclastic differentiation factors. The effects of B. breve CCFM1078 were different with age and gender dependent. This finding suggests B. breve CCFM1078 may have potential applications in regulating bone metabolism in the growth period population.

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Bifidobacterium longum subsp. infantis CCFM1269 promotes intestinal barrier and release of IFN-β through TLr4-TrIF dependent way in growing mice

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Food Science and Human Wellness 2024年

作者： Mengfan Ding Bo Yang Bowen Li Haiqin Chen renqiang Yu r.paul ross Catherine Stanton Shilong Jiang Jianxin Zhao Wei Chen State Key Laboratory of Food Science and resources， Jiangnan University School of Food Science and Technology， Jiangnan University International Joint research Center for Probiotics & Gut Health， Jiangnan University Department of Neonatology， Wuxi Maternity and Child Health Care Hospital， Affiliated Women's Hospital of Jiangnan University APC Microbiome Ireland， University College Cork Teagasc Food research Centre Nutrition and Metabolism research Division， Innovation Center， Heilongjiang Feihe Dairy Co.， Ltd. PKUHSC-China Feihe Joint research Institute of Nutrition and Healthy Lifespan Development National Engineering research Center for Functional Food， Jiangnan University

Bifidobacterium longum subsp. infantis is a commensal bacterium that predominates in the infant gut， playing a critical role in both preventing foreign infections and facilitating immune development. This study aimed to explore the effects of B. longum subsp. infantis supplementation on interferon-beta (IFN-β) secretion and intestinal barrier improvement in growing mice. Female and male mice were orally administered either saline or B. longum subsp. infantis CCFM1269 or I5TI (1 × 109CFU/mice per day， n = 8) from 1-week-age until 3-， 4-， and 5-week-age. rNA sequencing analysis revealed that CCFM1269 exhibited potential antiviral capacity through increasing 2’-5’ oligoadenylate synthetase (OAS). Additionally， CCFM1269 supplementation significantly increased colonic IFN-β levels which combined with OAS in 3-week-old female and male mice by activating the TLr4-TrIF-dependent signaling pathway. However， this effect was not observed in 4- and 5-week-old mice. Furthermore， both CCFM1269 were found to modulate the gut microbiota composition and enhance the intestinal barrier function in 3-， 4-， and 5-week-old mice. In summary， the results of this study suggested that B. longum subsp. infantis CCFM1269 promoting intestinal barrier and releasing IFN-β in growing mice was in a strain-specific and time-dependent manner.

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天然染料的分类、提取和牢度性能

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国外纺织技术 1997年第10期 27-31页

作者： r.paul 周秀会

合成染料的生产是从石油衍生物中分离出的初级化学物质为原料,在高温高压条件下进行多种反应,在其生产过程中会产生许多致癌物质。这些有毒的或对环境有害的物质不得不倾泻到河流、池溏或空气中,对环境造成严重污染。合成染料的以上缺... 详细信息

合成染料的生产是从石油衍生物中分离出的初级化学物质为原料,在高温高压条件下进行多种反应,在其生产过程中会产生许多致癌物质。这些有毒的或对环境有害的物质不得不倾泻到河流、池溏或空气中,对环境造成严重污染。合成染料的以上缺点已促使环保工作者寻找对环境无害的产品和生产技术,结果使天然产品尤其是天然染料的使用正成为热点。近年来,人们对天然染料越来越感兴趣,这

关键词：姜黄染料天然植物名称黄色染料牢度媒染剂染色助剂

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天然染料的分类、提取和牢度性能

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国外纺织技术（纺织针织服装化纤染整） 1997年第10期 27-31页

作者： r.paul 周秀会

关键词：天然染料分类提取牢度性能

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Limosilactobacillus mucosae FZJTZ26M3 prevents NAFLD in mice through modulation of lipid metabolism and gut microbiota dysbiosis

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Food Science and Human Wellness 2024年第3期13卷 1589-1601页

作者： Danting Dang Bowen Li Mengfan Ding rpaul ross Catherine Stanton Jianxin Zhao Bo Yang Wei Chen State Key Laboratory of Food Science and resources Jiangnan UniversityWuxi 214122China School of Food Science and Technology Jiangnan UniversityWuxi 214122China International Joint research Center for Probiotics&Gut Health Jiangnan UniversityWuxi 214122China APC Microbiome Ireland University College CorkCork T12 YT20Ireland Teagasc Food research Centre MooreparkFermoyCork T12 YT20Ireland National Engineering research Center for Functional Food Jiangnan UniversityWuxi 214122China

Lactobacillus are considered promising therapeutic methods for nonalcoholic fatty liver disease(NAFLD).The effects of two strains of Ltmosilactobacillus mucosae on NAFLD were investigated in this ***-old male C57BL/6J mice were divided into 4 groups(n=8 per group,Control,Model,FZJTZ26M3,FGSYC17L3).*** FZJTZ26M3 reduced the mice 's body weight,liver weight,and adipose tissue weight after 12 weeks of *** to serum analysis,total cholesterol,triacylglycerol,and low-density lipoprotein cholesterol significantly decreased after *** FZJTZ26M3 *** pathology showed that *** FZJTZ26M3 was effective to ameliorate lipid deposition in NAFLD ***,the expression of the gene related to lipid metabolism in the liver and adipose tissue was analyzed,and the results indicated that *** FZJTZ26M3 could alleviate NAFLD by regulating lipid ***,the results of 16S rrNA gene sequencing revealed a drop in the relative abundance of ruminococcaceae,which is linked to inflammation,but the relative abundance of a potential probiotic Akkermansia significantly increased after *** FZJTZ26M3 ***,*** FZJTZ26M3 could be a candidate to prevent NAFLD.

关键词： Limosilactobacillus mucosae Nonalcoholic fatty liver disease(NAFLD) Probiotic Lipid metabolism Gut microbiota

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