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Polyethylene glycol fusion repair of severed rat sciatic nerves reestablishes axonal continuity and reorganizes sensory terminal fields in the spinal cord

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Neural regeneration research 2025年第7期20卷 2095-2107页

作者： Emily A.Hibbard Liwen Zhou Cathy Z.Yang Karthik Venkudusamy Yessenia montoya Alexa Olivarez George D.Bittner Dale r.Sengelaub Program in Neuroscience Indiana UniversityBloomingtonINUSA Department of Neuroscience University of Texas at AustinAustinTXUSA

Peripheral nerve injuries result in the rapid degeneration of distal nerve segments and immediate loss of motor and sensory functions;behavioral recovery is typically *** used a plasmalemmal fusogen,polyethylene glycol(PEG),to immediately fuse closely apposed open ends of severed proximal and distal axons in rat sciatic *** have previously reported that sciatic nerve axons repaired by PEG-fusion do not undergo Wallerian degeneration,and PEG-fused animals exhibit rapid(within 2–6 weeks)and extensive locomotor ***,our previous report showed that PEG-fusion of severed sciatic motor axons was non-specific,i.e.,spinal motoneurons in PEG-fused animals were found to project to appropriate as well as inappropriate target *** this study,we examined the consequences of PEG-fusion for sensory axons of the sciatic *** adult male and female rats(Sprague–Dawley)received either a unilateral single cut or ablation injury to the sciatic nerve and subsequent repair with or without(Negative Control)the application of *** action potentials recorded immediately after PEG-fusion repair confirmed conduction across the injury *** success of PEG-fusion was confirmed through Sciatic Functional Index testing with PEG-fused animals showing improvement in locomotor function beginning at 35 days *** 2–42 days postoperatively,we anterogradely labeled sensory afferents from the dorsal aspect of the hindpaw following bilateral intradermal injection of wheat germ agglutinin conjugated horseradish ***-fusion repair reestablished axonal *** to unoperated animals,labeled sensory afferents ipsilateral to the injury in PEG-fused animals were found in the appropriate area of the dorsal horn,as well as inappropriate mediolateral and rostrocaudal ***,despite having intact peripheral nerves,similar reorganizations of labeled sensory afferents were also observed contralateral to the injury and repa

关键词： axotomy dorsal horn peripheral nerve injury plasticity polyethylene glycol(PEG) sciatic nerve sensory terminals wheat germ agglutinin horseradish peroxidase

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Head-on collision between single-and multi-soliton heavy ion acoustic waves in multi-ion plasmas

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Plasma Science and Technology 2019年第9期21卷 58-72页

作者： m S ALAm m r TALUKDEr Department of mathematics Chittagong University of Engineering and Technology Chittagong-4349 Bangladesh Plasma Science and Technology Lab Department of Electrical and Electronic Engineering University of Rajshahi Rajshahi-6205 Bangladesh

Head-on collisions among the single-and multi-soliton’s heavy ion acoustic waves(HIAWs) of multi-ion plasma are studied. The plasma consists of adiabatic positively charged inertial heavy ions, Boltzmann energy distributed light ions and kappa energy distributed electrons. The extended poincaré-Lighthill-Kuo(e PLK) method is applied for the derivation of two-sided Korteweg–de Vries(KdV) equations(KdVEs). The KdV single-soliton solutions(KdVSSs) are determined using the hyperbolic secant method and the KdV multi-soliton solutions(KdVmSs)are obtained using the Hirota method. The effects of superthermality of electrons, temperature ratios of electron to light ion and heavy ion to electron, and the density ratio of electron to heavy ion on phase shifts are investigated for the head-on collisions between two-soliton HIAWs. The effects of plasma parameters on angular frequency, phase speed, production of multi-soliton structures, and the head-on collisions among single-, double-, triple-, quadruple-, and quintuplesolitons are also studied.

关键词： HIAWs multi-soliton kappa-distribution ePLK method Hirotta's method multi-ion

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Dynamic modeling of a three-dimensional braided composite thin plate considering braiding directions

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 123-138页

作者： Chentong GAO Huiyu SUN Jianping GU W.m.HUANG College of Aerospace Engineering Nanjing University of Aeronautics and Astronautics School of mechanical and Aerospace Engineering Nanyang Technological University Jiangsu Key Laboratory of Advanced Structural materials and Application Technology School of Materials Science and EngineeringNanjing Institute of Technology

Currently, there are a limited number of dynamic models available for braided composite plates with large overall motions, despite the incorporation of three-dimensional(3D) braided composites into rotating blade components. In this paper, a dynamic model of 3D 4-directional braided composite thin plates considering braiding directions is established. Based on Kirchhoff's plate assumptions, the displacement variables of the plate are expressed. By incorporating the braiding directions into the constitutive equation of the braided composites, the dynamic model of the plate considering braiding directions is obtained. The effects of the speeds, braiding directions, and braided angles on the responses of the plate with fixed-axis rotation and translational motion, respectively, are investigated. This paper presents a dynamic theory for calculating the deformation of 3D braided composite structures undergoing both translational and rotational motions. It also provides a simulation method for investigating the dynamic behavior of non-isotropic material plates in various applications.

关键词： Constitutive equations

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Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function

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Neural regeneration research 2025年第10期20卷 2913-2914页

作者： William J.Flerlage mark L.Dell’Acqua Brian m.Cox Fereshteh S.Nugent Uniformed Services University of the Health Sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(Simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

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Comparative study of mo2Ga2C with superconducting mAX phase mo2GaC： First-principles calculations

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Chinese Physics B 2017年第3期26卷 297-302页

作者： m A Ali m r Khatun NJahan m m Hossain Department of Physics Chittagong University of Engineering and Technology Chittagong 4349 Bangladesh Department of Physics University of Rajshahi Rajshahi 6205 Bangladesh

The structural, electronic, optical and thermodynamic properties of mo2Ga2C are investigated using density func- tional theory （DFT） within the generalized gradient approximation （GGA）. The optimized crystal structure is obtained and the lattice parameters are compared with available experimental data. The electronic density of states （DOS） is calculated and analyzed. The metallic behavior for the compound is confirmed and the value of DOS at Fermi level is 4.2 states per unit cell per eV. Technologically important optical parameters （e.g., dielectric function, refractive index, absorption coefficient, photo conductivity, reflectivity, and loss function） are calculated for the first time. The study of dielectric constant （ε1） indicates the Drude-like behavior. The absorption and conductivity spectra suggest that the compound is metallic. The reflectance spectrum shows that this compound has the potential to be used as a solar reflector. The thermodynamic properties such as the temperature and pressure dependent bulk modulus, Debye temperature, specific heats, and thermal expansion coefficient of mo2Ga2C mAX phase are derived from the quasi-harmonic Debye model with phononic effect also for the first time. Analysis of Tc expression using available parameter values （DOS, Debye temperature, atomic mass, etc.） suggests that the compound is less likely to be superconductor.

关键词： first-principles calculations density of states (DOS) optical properties thermodynamic properties

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Linear and nonlinear torsional free vibration of functionally graded micro/nano-tubes based on modified couple stress theory

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Applied mathematics and mechanics(English Edition) 2016年第6期37卷 725-740页

作者： A.r.SETOODEH m.rEZAEI m.r.ZENDEHDEL SHAHrI Faculty of mechanical and Aerospace Engineering Shiraz University of Technology

The linear and nonlinear torsional free vibration analyses of functionmly graded micro/nuno-tubes （FGmTs） are analytically investigated based on the couple stress theory. The employed non-classical continuum theory contains one material length scale parameter, which can capture the small scale effect. The FGmT model accounts for the through-radius power-law variation of a two-constituent material. Hamilton＇s principle is used to develop the non-classical nonlinear governing equation. To study the effect of the boundary conditions, two types of end conditions, i.e., fixed-fixed and fixed-free, are considered. The derived boundary value governing equation is of the fourthorder, and is solved by the homotopy analysis method （HAm）. This method is based on the Taylor series with an embedded parameter and is capable of providing very good approximations by means of only a few terms, if the initial guess and the auxiliary linear operator are properly selected. The analytical expressions are developed for the linear and nonlinear natural frequencies, which can be conveniently used to investigate the effects of the dimensionless length scale parameter, the material gradient index, and the vibration amplitude on the natural frequencies of FGmTs.

关键词： torsional vibration nonlinear vibration micro/nano-tube functionallygraded material (FGm) couple stress theory size effect

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Heat Transfer Augmentation in Developing Flow Through a ribbed Square Duct

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Journal of Thermal Science 2006年第3期15卷 251-256页

作者： Khan r K Ali m.A.T Akhanda m.A.r Principal Polytechnic InstitutePotuakhaliBangladesh Department of mechanical Engineering Bangladesh University of Engineering and Technology(BUET)DhakaBangladesh Department of mechanical and Chemical Engineering Islamic University of Technology(IUT) OIC Gazipur-1704DhakaBangladesh

An experimental study is conducted to investigate the heat transfer augmentation in developing turbulent flow through a ribbed square duct. The duct is made of 16ram thick bakelite sheet. The bottom surface of the ribbed wall having rib pitch to height ratio of 10 is heated by passing a c current to the heater placed under it. The uniform heating is controlled using a digital temperature controller and a variac. The results of ribbed duct are compared with the results of a smooth duct under the same experimental conditions. It is observed that the heat transfer augmentation in ribbed duct is better than that of the smooth duct. At re=5.0× 10^4 , the mean temperature of air flowing through the ribbed duct increases by 2.45 percent over the smooth duct, whereas in the fibbed duct Nusselt number increases by 15.14 percent than that of the smooth duct with a 6 percent increase in pressure drop.

关键词： heat transfer square duct developing flow turbulent promoters

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rice plant growth and yield: foliar application of plasma activated water

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Plasma Science and Technology 2021年第7期23卷 134-143页

作者： m m rASHID mamunur rASHID m m HASAN m r TALUKDEr Plasma Science and Technology Lab Department of Electrical and Electronic EngineeringUniversity of RajshahiRajshahi 6205Bangladesh Plant Pathology and mycology Lab Department of BotanyUniversity of RajshahiRajshahi 6205Bangladesh Plant Pathology Lab Department of Agronomy and Agricultural ExtensionUniversity of RajshahiRajshahi 6205Bangladesh

Plasma activated water(PAW)was prepared for 10 min to be applied one toﬁve times as a foliar spray to rice plants,to investigate plant growth,yield and the concentrations of total soluble protein and sugar in the rice grains *** results reveal that(1)the plant height,stem diameter,dry weight,chlorophyll and total carotene concentrations were improved by∼15%,∼25%,∼24%,∼47%and∼45%,respectively,with respect to control,(2)defense mechanisms of the plants treated with PAW were improved,(3)concentrations of total soluble protein and sugar were enhanced in the rice grains of PAW treated plants and(4)yield was increased by∼14%.

关键词： plasma agriculture plasma activated water rice plant growth rice yield total soluble protein

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Analysis of bonded anisotropic wedges with interface crack under anti-plane shear loading

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Applied mathematics and mechanics(English Edition) 2014年第5期35卷 637-654页

作者： m.GHADIrI A.r.SHAHANI Faculty of Engineering Department of MechanicsImam Khomeini International University Department of Applied mechanics Faculty of Mechanical EngineeringK.N.Toosi University of Technology

The antiplane stress analysis of two anisotropic finite wedges with arbitrary radii and apex angles that are bonded together along a common edge is investigated. The wedge radial boundaries can be subjected to displacement-displacement boundary condi- tions, and the circular boundary of the wedge is free from any traction. The new finite complex transforms are employed to solve the problem. These finite complex transforms have complex analogies to both kinds of standard finite mellin transforms. The traction free condition on the crack faces is expressed as a singular integral equation by using the exact analytical method. The explicit terms for the strength of singularity are extracted, showing the dependence of the order of the stress singularity on the wedge angle, material constants, and boundary conditions. A numerical method is used for solving the resul- tant singular integral equations. The displacement boundary condition may be a general term of the Taylor series expansion for the displacement prescribed on the radial edge of the wedge. Thus, the analysis of every kind of displacement boundary conditions can be obtained by the achieved results from the foregoing general displacement boundary condition. The obtained stress intensity factors （SIFs） at the crack tips are plotted and compared with those obtained by the finite element analysis （FEA）.

关键词： antiplane stress analysis anisotropic elastic wedge stress intensity factor(SIF) displacement-displacement boundary conditions singular integral equation

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Spectral Behavior and Flaring Activity ofⅡPeg in the Ultraviolet

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research in Astronomy and Astrophysics 2022年第8期22卷 191-197页

作者： m.r.Sanad Astronomy Department National Research Institute of Astronomy and GeophysicsHelwanCairoEgypt

We have studied the spectral behavior of theⅡPeg binary system in the ultraviolet band by using International Ultraviolet Explorer(IUE)observations over the period *** ultraviolet observations reveal indication of flare activity in both chromosphere and transition region with their enhanced emission *** and after the flare activity the ultraviolet emission lines show low,intermediate and high *** spectral behavior is compared with previous *** detect prominent flare activity in 1989,1990 and *** and after this period there is a gradual clear decrease in the level of *** reddening ofⅡPeg was determined from a 2200?absorption feature to be E(B-V)=0.10±*** ascertained the average mass loss rate to be≈1×10^(-8)m_(☉)yr^(-1),and an average ultraviolet luminosity to be≈6×10^(29)erg s^(-1).We attributed the spectral variations to a cyclic behavior of the underlying magnetic dynamo and the prominent activity can be interpreted by the model of a two-ribbon flare.

关键词： line:profiles magnetic fields stars:activity stars:flare ultraviolet:stars

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