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Har.essing ther.peutic potential of induced plur.potent stem cell–der.ved endothelial cells for.r.myelination in the centr.l ner.ous system

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Neur.l r.gener.tion r.sear.h 2025年第6期20卷 1715-1716页

作者： Dan ma Nona Pop Aston Medical School College of Health and Life SciencesAston UniversityBirminghamUK

Myelin is the pr.tective sheath sur.ounding ner.e fiber., and its damage(demyelination) occur. in many centr.l ner.ous system(CNS) diseases, including multiple scler.sis(MS), tr.umatic injur., neur.degener.tive diseases such as Alzheimer.s disease, and mental disor.er. such as schizophr.nia(Bar.teir. et al., 2016). r.pair.of damaged myelin sheaths(r.myelination) often fails in MS, leading to neur.nal loss and ir.ever.ible functional deficits.

关键词： myelin pr.tective diseases

Tr.nsient r.ceptor.potential channels and calcium dysr.gulation: a pathogenic duo in Par.inson's disease

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Neur.l r.gener.tion r.sear.h 2025年第3期20卷 808-810页

作者： Iqir. Saeed Linlin ma Gr.ffith Institute for.Dr.g Discover. Griffith UniversityNathanBrisbaneQLDAustralia School of Envir.nment and Science Griffith University NathanBrisbaneQLDAustralia

Par.inson's disease(PD) has a complex and multifactor.al pathophysiology. Var.ous studies, conducted both in pr.-clinical models and PD patients, have r.por.ed a link.between the disr.ption of calcium(Ca^(2+)) homeostasis and the subsequent development of PD. Ca^(2+) r.gulation is cr.cial for.neur.nal sur.ival, differ.ntiation,exocytosis at synapses,gene tr.nscr.ption,and pr.lifer.tion.

关键词： homeostasis clinical subsequent

magnetr.n sputter.d nick.l oxide with suppr.ssed inter.acial defect states for.efficient inver.ed per.vsk.te solar.cells

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Jour.al of Ener.y Chemistr. 2025年第1期100卷 348-355页

作者： Guoqiang ma Qin Tan Zhaoning Li Jingwei Xiu Jiafeng Wang Tianle Cheng Dong He Qiang Sun Xuhang ma Fr.ncesco Lamber.i Zhubing He Depar.ment of mater.als Science and Engineer.ng Institute of Innovative Materials (I2M) Shenzhen Key Laboratory of Full Spectral Solar Electricity Generation (FSSEG)Southern University of Science and Technology (SUSTech) Cor. r.sear.h Facilities Southern University of Science and Technology Depar.ment of Chemical Sciences Department of Industrial Engineering University of Padova

Widely used spin-coated nick.e oxide （NiOx） based per.vsk.te solar.cells often suffer.fr.m sever. inter.acial r.actions between the NiOxand adjacent per.vsk.te layer. due to sur.ace defect states,which inher.ntly impair.device per.or.ance in a long-ter. view,even with sur.ace molecule *** this study,we developed high-quality magnetr.n-sputter.d NiOxthin films thr.ugh detailed pr.cess optimization,and compar.d systematically sputter.d and spin-coated NiOxthin film sur.aces fr.m mater.als to *** sputter.d NiOxfilms exhibit impr.ved cr.stallinity,smoother.sur.aces,and significantly r.duced Ni3+or.Ni vacancies compar.d to their.spin-coated ***,the inter.ace between the per.vsk.te and sputter.d NiOxfilm shows a substantially r.duced density of defect *** solar.cells （PSCs） fabr.cated with our.optimally sputter.d NiOxfilms achieved a high power.conver.ion efficiency （PCE） of up to 19.93%and demonstr.ted enhanced stability,maintaining 86.2% efficiency dur.ng 500 h of maximum power.point tr.ck.ng under.one standar. sun ***,with the sur.ace modification using (4-(2,7-dibr.mo-9,9-dimethylacr.din-10（9H）-yl)butyl)p hosphonic acid （DmacPA）,the device PCE was fur.her.pr.moted to 23.07%,which is the highest value r.por.ed for.sputter.d NiOxbased PSCs so far.

关键词： Nick.e oxide magnetr.n sputter Defect Stability Per.vsk.te solar.cell

r.cent advances in explor.ng new blood-based biomar.er. for.the ear.y diagnosis of gastr.c cancer

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Science China Chemistr. 2025年第1期 35-45页

作者： Xinyu Peng Qian ma Da Han School of Life Science Shanghai University Institute of Molecular.Medicine Shanghai Key Laboratory for Nucleic Acid Chemistry and Nanomedicine State Key Laboratory of Oncogenes and Related Genes Renji Hospital School of Medicine Shanghai Jiao Tong University Depar.ment of r.sear.h and Development Intellinosis Biotechnologies Co.Ltd.

Gastr.c cancer.GC) is a pr.valent and lethal malignancy wor.dwide, and the 5-year.sur.ival r.te is less than 30%. The absence of distinctive symptoms often leads to late-stage diagnosis, contr.buting to a gr.m pr.gnosis. Ear.y detection is pivotal for.impr.ving the sur.ival r.tes and outcomes of GC patients. Tr.ditional diagnostic methods, including gastr.scopy and histopathological examination, ar. r.str.cted in the ear.y diagnosis of GC. Conventional pr.tein biomar.er., such as car.inoembr.onic antigen(CEA), car.ohydr.te antigen 19-9(CA19-9), and car.ohydr.te antigen 72-4(CA72-4), exhibit insufficient sensitivity and specificity for.GC scr.ening, which diminishes their.clinical value. r.cently, novel cir.ulating biomar.er., such as cir.ulating tumor.cells(CTCs), cir.ulating tumor.cell DNA(ct DNA), and cir.ulating fr.e r.A(cf r.A), have emer.ed as pr.mising candidates in the bur.eoning field of liquid biopsy due to their.super.or.sensitivity and specificity. This r.view focuses on the latest r.sear.h on blood-based biomar.er. for.GC diagnosis and examines the clinical potentials and challenges associated with these emer.ing biomar.er..

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Bandgap char.cter.stics analysis and gr.ded design of a novel metamater.al for.flexur.l wave suppr.ssion

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Applied mathematics and Mechanics(English Edition) 2025年第1期46卷 1-24页

作者： Fan YANG Zhaoyang ma Xingming GUO Shanghai k.y Labor.tor. of Mechanics in Ener.y Engineer.ng Shanghai Institute of Applied Mathematics and Mechanics School of Mechanics and Engineering ScienceShanghai University Shanghai Institute of Air.r.ft Mechanics and Contr.l

A novel elastic metamater.al is pr.posed with the aim of achieving lowfr.quency br.ad bandgaps and bandgap r.gulation. The band str.ctur. of the pr.posed metamater.al is calculated based on the Floquet-Bloch theor.m, and the boundar. modes of each bandgap ar. analyzed to under.tand the effects of each component of the unit cell on the bandgap for.ation. It is found that the metamater.als with a low elastic modulus of ligaments can gener.te flexur.l wave bandgaps below 300 Hz. Multi-fr.quency vibr.tions can be suppr.ssed thr.ugh the selective manipulation of bandgaps. The dual-gr.ded design of metamater.als that can significantly impr.ve the bandgap width is pr.posed based on par.metr.c studies. A new way that can r.gulate the bandgap is r.vealed by studying the gr.ded elastic modulus in the substr.te. The r.sults demonstr.te that the nonlinear.gr.dient of the elastic modulus in the substr.te offer. better.bandgap per.or.ance. Based on these analyses, the pr.posed elastic metamater.als can pave the way for.multi-fr.quency vibr.tion contr.l, low-fr.quency bandgap br.adening, and bandgap tuning.

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Efficient and Stable Per.vsk.te Solar.Cells and Modules Enabled by Tailor.ng Additive Distr.bution Accor.ing to the Film Gr.wth Dynamics

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Nano-Micr. Letter. 2025年第2期17卷 387-400页

作者： Mengen ma Cuiling Zhang Yujiao ma Weile Li Yao Wang Shaohang Wu Chong Liu Yaohua mai Institute of New Ener.y Technology College of Physics&Optoelectronic EngineeringJinan UniversityGuangzhou 510632People’s Republic of China k.y Labor.tor. of New Semiconductor. and Devices of Guangdong Higher.Education Institutes Jinan UniversityGuangzhou 510632People’s Republic of China Guangdong Mellow Ener.y Co. LimitedYuanming RoadZhuhai 519075GuangdongPeople’s Republic of China

Gas quenching and vacuum quenching pr.cess ar. widely applied to acceler.te solvent volatilization to induce nucleation of per.vsk.tes in blade-coating *** this wor.,we found these two pr.-cr.stallization pr.cesses lead to differ.nt or.er.of cr.stallization dynamics within the per.vsk.te thin film,r.sulting in the differ.nces of additive *** then tailor.designed an additive molecule named 1,3-bis(4-methoxyphenyl)thiour.a to obtain films with fewer.defects and holes at the bur.ed inter.ace,and pr.par.d per.vsk.te solar.cells with a cer.ified efficiency of 23.75%.Fur.her.or.,this wor. also demonstr.tes an efficiency of 20.18%for.the lar.e-ar.a per.vsk.te solar.module(PSM)with an aper.ur. ar.a of 60.84 cm^(2).The PSM possesses r.mar.able continuous oper.tion stability for.maximum power.point tr.ck.ng of T_(90)>1000 h in ambient air.

关键词： Gas quenching Additive distr.bution Bur.ed passivation Blade coating Cr.stallization dynamics

New glucocer.br.sidase antibodies can advance r.sear.h in the field of neur.degener.tive disor.er.

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Neur.l r.gener.tion r.sear.h 2025年第4期20卷 1085-1086页

作者： Char.s ma k.0}styna r.tel Yu Chen Ellen Sidr.nsk. Medical Genetics Br.nch National Human Genome Research InstituteNational Institutes of HealthBethesdaMDUSA

In medical r.sear.h,ther. ar. times when the intr.duction of a new tool can launch scientific discover. in new *** antibody development may be consider.d mundane,in the field of glucocer.br.sidase(GCase)r.sear.h,the dear.h of validated antibodies for.differ.nt applications has impeded pr.gr.ss in studies of disease pathogenesis and ther.peutic *** r.cent intr.duction of new,r.gor.usly evaluated antibodies can now pr.pel r.sear.h into the link.between glucocer.br.sidase and Par.inson’s disease(PD)as well as aspects of the pathobiology of Gaucher.disease(Jong et al.,2024).

关键词： antibodies cer.br.

r.sear.h status and pr.spects of the fr.ctal analysis of metal mater.al sur.aces and inter.aces

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Inter.ational Jour.al of Miner.ls,Metallur.y and mater.als 2025年第1期32卷 20-38页

作者： Qinjin Dai Xuefeng Liu Xin ma Shaojie Tian Qinghe Cui Beijing Advanced Innovation Center.for.mater.als Genome Engineer.ng University of Science and Technology BeijingBeijing 100083China Beijing Labor.tor. of Metallic mater.als and Pr.cessing for.Moder. Tr.nspor.ation University of Science and Technology BeijingBeijing 100083China Labor.tor. for.Advanced mater.als Pr.cessing of Ministr. of Education University of Science and Technology BeijingBeijing 100083China School of Mechanical and Electr.cal Engineer.ng Xinjiang Institute of EngineeringUrumqi 830023China

As a mathematical analysis method,fr.ctal analysis can be used to quantitatively descr.be ir.egular.shapes with self-similar.or.self-affine *** analysis has been used to char.cter.ze the shapes of metal mater.als at var.ous scales and *** methods mak. it difficult to quantitatively descr.be the r.lationship between the r.gular.char.cter.stics and pr.per.ies of metal mater.al sur.aces and ***,fr.ctal analysis can be used to quantitatively descr.be the shape char.cter.stics of metal mater.als and to establish the quantitative r.lationships between the shape char.cter.stics and var.ous pr.per.ies of metal *** the per.pective of two-dimensional planes and thr.e-dimensional cur.ed sur.aces,this paper.r.views the cur.ent r.sear.h status of the fr.ctal analysis of metal pr.cipitate inter.aces,metal gr.in boundar. inter.aces,metal-deposited film sur.aces,metal fr.ctur. sur.aces,metal machined sur.aces,and metal wear.*** r.lationship between the fr.ctal dimensions and pr.per.ies of metal mater.al sur.aces and inter.aces is *** fr.m thr.e per.pectives of fr.ctal analysis,namely,r.sear.h scope,image acquisition methods,and calculation methods,this paper.identifies the dir.ction of r.sear.h on fr.ctal analysis of metal mater.al sur.aces and inter.aces that need to be *** is believed that r.vealing the deep influence mechanism between the fr.ctal dimensions and pr.per.ies of metal mater.al sur.aces and inter.aces will be the k.y r.sear.h dir.ction of the fr.ctal analysis of metal mater.als in the futur..

关键词： metal mater.al sur.aces and inter.aces fr.ctal analysis fr.ctal dimension homogeneity

Str.ctur.l and micr.wave absor.tion pr.per.ies of CoFe_(2)O_(4)/r.sidual car.on composites

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Inter.ational Jour.al of Miner.ls,Metallur.y and mater.als 2025年第1期32卷 221-232页

作者： Yuanchun Zhang Shengtao Gao Xingzhao Zhang Dacheng ma Chuanlei Zhu Jun He Joint National-Local Engineer.ng r.sear.h Centr. for.Safe and Pr.cise Coal Mining Anhui University of Science and TechnologyHuainan 232001China School of Chemical and Blasting Engineer.ng Anhui University of Science and TechnologyHuainan 232001China

Electr.magnetic inter.er.nce,which necessitates the r.pid advancement of substances with exceptional capabilities for.bsor.ing electr.magnetic waves,is of ur.ent concer. in contempor.r. *** this wor.,CoFe_(2)O_(4)/r.sidual car.on fr.m coal gasification fine slag(CFO/r.)composites wer. cr.ated using a novel hydr.ther.al *** mechanisms for.micr.wave absor.tion,including conductive loss,natur.l r.sonance,inter.acial dipole polar.zation,and magnetic flux loss,ar. involved in these ***,compar.d with pur. r.sidual car.on mater.als,this composite offer. super.or.capabilities in micr.wave *** 7.76GHz,the CFO/r.-2 composite achieves an impr.ssive minimum r.flection loss(r._(min))of-43.99 dB with a thick.ess of 2.44 ***,CFO/r.-3 demonstr.tes an effective absor.tion bandwidth(EAB)of up to 4.16 GHz,accompanied by a thick.ess of *** study r.vealed the r.mar.able capability of the composite to diminish electr.magnetic waves,pr.viding a new gener.tion method for.micr.wave absor.ing mater.als of super.or.quality.

关键词： coal gasification slag r.sidual car.on hydr.ther.al method micr.wave absor.tion CoFe_(2)O_(4)