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Time aver.ged consensus in a dir.ct coupled coher.nt quantum obser.er.networ.

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Contr.l Theor. and Technology 2017年第3期15卷 163-176页

作者： ian r. PETEr.EN r.sear.h School of Engineer.ng The Australian National University Canberra ACT 2601 Australia

This paper.consider. the pr.blem of constr.cting a dir.ct coupling quantum obser.er.for.a closed linear.quantum system. The pr.posed distr.buted obser.er.consists of a networ. of quantum har.onic oscillator. and it is shown that the obser.er.networ. conver.es to a consensus in a time aver.ged sense in which each element of the obser.er.estimates the specified output of the quantum plant. An example and simulations ar. included to illustr.te the pr.per.ies of the obser.er.networ..

关键词： Quantum systems quantum obser.er. quantum networ.s

Coar.e to Fine: The r.le of Sever. Plastic Defor.ation in Advancing Titanium-Based Medical Implants - A Compr.hensive r.view

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Jour.al of Wuhan Univer.ity of Technology(Mater.als Science) 2025年第1期40卷 295-306页

作者： Dr.gana r.Mihajlović Bojan I Međo Ivana Lj Cvijović-Alagić Veljko r.Djokić Faculty of Technology and Metallur.y University of BelgradeKarnegijeva 411120 BelgradeSerbia Vinča Institute of Nuclear.Sci-ences-National Institute of the r.public of Ser.ia University of Belgrade11001BeogradSerbia Innovation Centr. of the Faculty of Technology and Metallur.y Karnegijeva 411120 BelgradeSerbia

This paper.descr.bes sever. plastic defor.ation(SPD)pr.cedur.s,which ar. utilized to for. an ultr.fine-gr.ined str.ctur. in metallic *** the SPD pr.cess,a solid mater.al sample is subjected to ver. high loads without a significant change in sample *** the pr.sent wor.,the high-pr.ssur. tor.ion(HPT)pr.cess,as one of the SPD techniques,which achieves a high degr.e of defor.ation and ensur.s r.finement of the micr.str.ctur.,will be discussed in mor. *** that gr.in size contr.l is accepted as a method to obtain mater.als with desir.d char.cter.stics,an over.iew of the pr.per.ies of ultr.fine-gr.ined titanium-based biomater.als to be used in medicine is ***,par.icular.attention is dedicated to the influences of HPT pr.cess par.meter.,pr.mar.ly hydr.static pr.ssur.,and number.of r.volutions dur.ng tor.ion,on the gr.in size and physical and mechanical char.cter.stics(modulus of elasticity,micr.har.ness,and tensile pr.per.ies),cor.osion r.sistance,and biocompatibility of the titanium-based biomater.als.A r.view of the liter.tur. indicates that titanium-based mater.als obtained by the SPD pr.cess show impr.ved mechanical and physical pr.per.ies without losing biocompatibility and cor.osion r.sistance,which suggests that these methods of obtaining implants ar. something that should be fur.her.developed in the futur..

关键词： high-pr.ssur. tor.ion pr.cess ultr.fine-gr.ined titanium-based mater.als electr.chemical anodization physical pr.per.ies mechanical pr.per.ies

Emer.ing potential of pr.gr.nulin-dependent Sor.S2 signaling in healthy and diseased ner.ous systems

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Neur.l r.gener.tion r.sear.h 2025年第9期20卷 2591-2593页

作者： Alena Salasova Ander. Nykjær Danish r.sear.h Institute of Tr.nslational Neur.science DANDr.TE-Nor.ic EMBL Par.ner.hip for.Molecular.Medicine and Centre of Excellence PROMEMODepartment of BiomedicineAarhus UniversityAarhusDenmark

The for.ation of the mammalian ner.ous system and its matur.tion into sensor.,motor.cognitive,and behavior.l cir.uits is a complex pr.cess that begins dur.ng ear.y embr.ogenesis and lasts until young *** neur.developm... 详细信息

关键词： pr.gr jointly CS2

Secur.ty Str.tegy of Digital Medical Contents Based on Blockchain in Gener.tive AI Model

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Computer., Mater.als & Continua 2025年第1期82卷 259-278页

作者： Hoon Ko Mar.k r.Ogiela Division of Computer.Science and Engineer.ng Sunmoon UniversityAsan31460Republic of Korea AGH Univer.ity of Kr.kow Cryptography and Cognitive Informatics LaboratoryKrakow30-059Poland

This study pr.sents an innovative appr.ach to enhancing the secur.ty of visual medical data in the gener.tive AI envir.nment thr.ugh the integr.tion of blockchain *** combining the str.ngths of blockchain and gener.tive AI,the r.sear.h team aimed to addr.ss the timely challenge of safeguar.ing visual medical *** par.icipating r.sear.her. conducted a compr.hensive analysis,examining the vulner.bilities of medical AI ser.ices,per.onal infor.ation pr.tection issues,and over.ll secur.ty *** multi faceted explor.tion led to an indepth evaluation of the model’s per.or.ance and ***,the cor.elation between accur.cy,detection r.te,and er.or.r.te was *** analysis r.vealed insights into the model’s str.ngths and limitations,while the consider.tion of standar. deviation shed light on the model’s stability and per.or.ance *** study pr.posed pr.ctical impr.vements,emphasizing the r.duction of false negatives to enhance detection r.te and lever.ging blockchain technology to ensur. visual data integr.ty in medical *** blockchain to gener.tive AI-cr.ated medical content addr.sses key per.onal infor.ation pr.tection *** utilizing the distr.buted ledger.system of blockchain,the r.sear.h team aimed to pr.tect the pr.vacy and integr.ty of medical data especially medical *** appr.ach not only enhances secur.ty but also enables tr.nspar.nt and tamper.r.of ***,the use of gener.tive AI models ensur.s the cr.ation of novel medical content without compr.mising per.onal infor.ation,fur.her.safeguar.ing patient *** conclusion,this study showcases the potential of blockchain-based solutions in the medical field,par.icular.y in secur.ng sensitive medical data and pr.tecting patient *** pr.posed appr.ach,combining blockchain and gener.tive AI,offer. a pr.mising dir.ction towar. mor. r.bust and secur. medical content *** r.sear.h and advancements

关键词： Digitalmedical content medical diagnostic visualization secur.ty analysis gener.tiveAI blockchain vulner.bility patter. r.cognition

Epigenetic contr.l of meiotic r.combination in plants

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Science China(Life Sciences) 2015年第3期58卷 223-231页

作者： YELINA Natasha DIAZ Patr.ck LAMBING Chr.stophe HENDEr.ON ian r. Depar.ment of Plant Sciences University of Cambridge

Meiotic r.combination is a deeply conser.ed pr.cess within eukar.otes that has a pr.found effect on patter.s of natur.l genetic var.ation. Dur.ng meiosis homologous chr.mosomes pair.and under.o DNA double str.nd br.aks gener.ted by the Spo11 endonuclease. These br.aks can be r.pair.d as cr.ssover. that r.sult in r.cipr.cal exchange between chr.mosomes. The fr.quency of r.combination along chr.mosomes is highly var.able, for.example, cr.ssover. ar. r.r.ly obser.ed in heter.chr.matin and the centr.mer.c r.gions. r.cent wor. in plants has shown that cr.ssover.hotspots occur.in gene pr.moter. and ar. associated with specific chr.matin modifications, including H2 A.Z. Meiotic chr.mosomes ar. also or.anized in loop-base ar.ays connected to an under.ying chr.mosome axis, which likely inter.cts with chr.matin to or.anize patter.s of ***, epigenetic infor.ation exer.s a major.influence on patter.s of meiotic r.combination along chr.mosomes, genetic var.ation within populations and evolution of plant genomes.

关键词： meiosis r.combination epigenetic cr.ssover chr.matin

Enhanced Electr.activity of Facet-Contr.lled Co3O4 Nanocr.stals for.Enzymeless Biosensing

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Jour.al of Mater.als Science & Technology 2016年第1期32卷 24-27页

作者： Kuang-HsuWu Xue Leng ian r. Gentle Da-Wei Wang School of Chemistr. and Molecular.Biosciences the University of Queensland Brisbane QLD 4072 Australia School of Chemical Engineer.ng the University of New South Wales Sydney NSW 2052 Australia

In this wor., we r.por. enhanced electr.activity of Co304 nanocr.stals （nanocubes, NCs and tr.ncated nano-octahedr., TNO） on the exposed {111} facets as compar.d to the {001} facets in r.lation to the sur.ace density and the activity of the octahedr.l Com species. Tr.nsmission electr.n micr.scopy, X-r.y powder.diffr.ction, X-r.y photoelectr.n spectr.scopy and Four.er.tr.nsfor. infr.r.d spectr.scopy wer. em- ployed to char.cter.ze the cr.stal facets and mater.als pr.per.ies. The enhanced electr.activity of {111 } cr.stal facets was evaluated by cyclic voltammetr. and amper.metr.c titr.tion. Our.r.sults indicate that the {111 } facets in TNO has a better.electr.activity for.enzymeless glucose sensing with a decent glucose sensitivity of 32.54 μA （mmol/L）-1 cm-2.

关键词： Co304 nanopar.icles Cr.stal facets Glucose sensing

Antisense oligonucleotides pr.vide optimism to the ther.peutic landscape for.tauopathies

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Neur.l r.gener.tion r.sear.h 2025年第3期20卷 803-804页

作者： Glenn A.Har.is Laur.n r.Hir.chfeld r.inwater.Char.table Foundation Fort WorthTXUSA

Tauopathies ar. a gr.up of neur.degener.tive diseases char.cter.zed by abnor.al metabolism of the misfolded tau pr.tein. Tau is encoded by the micr.tubule-associated pr.tein tau gene(MAPT) and can be classified as either.3-r.peat(3r. or.4-r.peat(4r. based on the number.of r.peat domains fr.m alter.ative splicing of exon 10 of the MAPT gene.

关键词： tau metabolism diseases

Machine Lear.ing Techniques in Pr.dicting Hot Defor.ation Behavior.of Metallic Mater.als

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Computer.Modeling in Engineer.ng & Sciences 2025年第1期142卷 713-732页

作者： Petr.Opela Josef Walek Jar.mír.Kopecek Depar.ment of Metallur.ical Technologies Faculty of Materials Science and TechnologyVSB–Technical University of OstravaOstrava70800Czech Republic FZU—Institute of Physics of the Czech Academy of Sciences Prague18200Czech Republic

In engineer.ng pr.ctice,it is often necessar. to deter.ine functional r.lationships between dependent and independent *** r.lationships can be highly nonlinear.and classical r.gr.ssion appr.aches cannot always pr.vide sufficiently r.liable ***,Machine Lear.ing(ML)techniques,which offer.advanced r.gr.ssion tools to addr.ss complicated engineer.ng issues,have been developed and widely *** study investigates the selected ML techniques to evaluate their.suitability for.application in the hot defor.ation behavior.of metallic *** ML-based r.gr.ssion methods of Ar.ificial Neur.l Networ.s(ANNs),Suppor. Vector.Machine(SVM),Decision Tr.e r.gr.ssion(DTr.,and Gaussian Pr.cess r.gr.ssion(GPr.ar. applied to mathematically descr.be hot flow str.ss cur.e datasets acquir.d exper.mentally for.a medium-car.on *** the GPr.method has not been used for.such a r.gr.ssion task befor.,the r.sults showed that its per.or.ance is the most favor.ble and pr.ctically unr.valed;neither.the ANN method nor.the other.studied ML techniques pr.vide such pr.cise r.sults of the solved r.gr.ssion analysis.

关键词： Machine lear.ing Gaussian pr.cess r.gr.ssion ar.ificial neur.l networ.s suppor. vector.machine hot defor.ation behavior

Effects of symmetr.c and asymmetr.c salt conditions on a selective solid-state nanopor. assay

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Nano r.sear.h 2022年第11期15卷 9936-9942页

作者： ian D.Wadswor.h Adam r.Hall Vir.inia Tech-Wake For.st Univer.ity School of Biomedical Engineer.ng and Sciences Wake Forest School of MedicineWinston-SalemNC 27101USA Compr.hensive Cancer.Center Wake Forest School of MedicineWinston-SalemNC 27157USA

Conventional solid-state nanopor. measur.ments sense all tr.nslocating entities,necessitating meticulous analysis to differ.ntiate tar.et *** addr.ss this,we have established a selective assay with the platfor. that has shown utility in quantifying sever.l nucleic acid ***,limited detection efficiency and intr.nsic noise have so far.limited assay r.solution to 10 *** in this value r.quir. manipulation of tr.nslocation ***,we r.por. the effects of NaCl conditions on assay *** fir.t investigate symmetr.c conditions,finding sensitivity incr.ases with salt concentr.tion but selectivity is maximized at 1.0 M *** then pr.be asymmetr.c conditions,showing a r.mar.able impact on assay sensitivity and selectivity when measur.ment buffer.NaCl concentr.tion in the r.ser.oir.with the tr.nslocating molecules is low and the opposite r.ser.oir.is *** optimum conditions,we demonstr.te detection of tar.et biomolecules down to a concentr.tion of 100 pM which is an impr.vement of 2 or.er. of magnitude over.past r.sults.

关键词： solid-state nanopor.s biomar.er. amplification-fr.e detection salt gr.dient nucleic acids