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Chinese Physics B 2016年第4期25卷 358-364页

作者： r m rosnan Z Othaman r Hussin Ali A Ati Alireza Samavati Shadab Dabagh samad Zare Centre for Sustainable Nanomaterials Ibnu Sina Institute for Scientific and Industrial Research Universiti Teknologi Malaysia 81310 Skudai Johor Bahru Malaysia

In this study, nanocrystalline Co-Ni-mg ferrite powders with composition Coo.5Nio.5-xmgxFe2O4 are successfully synthesized by the co-precipitation method. A systematic investigation on the structural, morphological and magnetic properties of un-doped and mg-doped Co-Ni ferrite nanoparticles is carried out. The prepared samples are characterized using x-ray diffraction （XrD） analysis, Fourier transform infrared spectroscopy （FTIr）, field emission scanning electron microscopy （FESEm）, and vibrating sample magnetometry （VSm）. The XrD analyses of the synthesized samples confirm the formation of single-phase cubic spinel structures with crystallite sizes in a range of - 32 nm to - 36 nm. The lat- tice constant increases with increasing mg content. FESEm images show that the synthesized samples are homogeneous with a uniformly distributed grain. The results of Ir spectroscopy analysis indicate the formation of functional groups of spinel ferrite in the co-precipitation process. By increasing mg2- substitution, room temperature magnetic measurement shows that maximum magnetization and coercivity increase from - 57.35 emu/g to - 61.49 emu/g and - 603.26 Oe to 684.11 Oe （l Oe = 79.5775 A.m-l）, respectively. The higher values of magnetization ms and mr suggest that the opti- mum composition is Co0.5Ni0.4mg0.1Fe204 that can be applied to high-density recording media and microwave devices.

关键词： co-precipitation magnetic materials spinel ferrite magnetic properties

Heterogeneity of mature oligodendrocytes in the central nervous system

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Neural regeneration research 2025年第5期20卷 1336-1349页

作者： Chao Weng Adam m.r.Groh moein Yaqubi Qiao-Ling Cui Jo Anne Stratton G.r.Wayne moore Jack P.Antel Neuroimmunology Unit Montreal Neurological Institute-HospitalDepartment of Neurology and NeurosurgeryMcGill UniversityMontrealQCCanada Department of Neurology Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous *** evidence has challenged the classical view of the functionally static mature oligodendrocyte and revealed a gamut of dynamic functions such as the ability to modulate neuronal circuitry and provide metabolic support to *** the recognition of potential heterogeneity in mature oligodendrocyte function,a comprehensive summary of mature oligodendrocyte diversity is *** delve into early 20th-century studies by robertson and río-Hortega that laid the foundation for the modern identification of regional and morphological heterogeneity in mature ***,recent morphologic and functional studies call into question the long-assumed homogeneity of mature oligodendrocyte function through the identification of distinct subtypes with varying myelination ***,modern molecular investigations,employing techniques such as single cell/nucleus rNA sequencing,consistently unveil at least six mature oligodendrocyte subpopulations in the human central nervous system that are highly transcriptomically diverse and vary with central nervous system *** and disease related mature oligodendrocyte variation denotes the impact of pathological conditions such as multiple sclerosis,Alzheimer's disease,and psychiatric ***,caution is warranted when subclassifying mature oligodendrocytes because of the simplification needed to make conclusions about cell identity from temporally confined *** studies leveraging advanced techniques like spatial transcriptomics and single-cell proteomics promise a more nuanced understanding of mature oligodendrocyte *** research avenues that precisely evaluate mature oligodendrocyte heterogeneity with care to understand the mitigating influence of species,sex,central nervous system region,age,and disease,

关键词： aging central nervous system diseases electron microscopy heterogeneity immunohistochemistry myelin sheath natural history neuroglia oligodendroglia single-cell gene expression analysis

Getting physical with medical education:Exercise based virtual anatomy review classes for medical students

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World Journal of methodology 2025年第1期15卷 20-25页

作者： Nadeesha r Samarasinghe Taniya S Nagpal michele L Barbeau Charys m martin Division of General Surgery Faculty of MedicineUniversity of British ColumbiaVancouver V6T 1Z3BCCanada Faculty of Kinesiology Sport and RecreationUniversity of AlbertaEdmonton T6G 2R3ABCanada Anatomy and Cell Biology University of Western OntarioLondon N6A 3K7ONCanada Department of Anatomy and Cell Biology Schulich School of Medicine and DentistryThe University of Western OntarioLondon N6A 3K7ONCanada

The benefits of regular physical activity are well ***,few studies have examined the effectiveness of integrating physical activity(PA)into curricula within a post-secondary *** investigate the incorporation of PA into medical curriculum,we developed a series of optional exercise-based review sessions designed to reinforce musculoskeletal(mSK)anatomy course *** synchronous sessions were co-taught by a group fitness instructor and an anatomy *** fitness instructor would lead students through both strength and yoga style exercises,while the anatomy instructor asked questions about relevant anatomical structures related to course material previously *** the sessions,participants were asked to evaluate the classes on their self-reported exam preparedness in improving mSK anatomy knowledge,PA levels,and mental *** participants completed surveys;a majority agreed that the classes increased understanding of mSK concepts(90.0%)and activity levels(97.7%).many(70.0%)felt that the classes helped reduce *** majority of respondents(90.0%)agreed that the classes contributed to increased feelings of social ***,medical students saw benefit in PA based interventions to supplement mSK course *** with increasing activity levels and promoting health behaviours,integrating PA into medical curriculum may improve comprehension of learning material,alleviate stress and foster social connectivity among medical students.

关键词： medical education musculoskeletal Anatomy Exercise Online learning

Charaeterizability of the Group ~2D_p(3) by its Order Components,Where p≥5 is a Prime Number Not of the Form 2~m+1

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Acta mathematica Sinica,English Series 2008年第7期24卷 1117-1126页

作者： m.r.DArAFSHEH School of mathematics College of ScienceUniversity of TehranTehranIran

The author will prove that the group ^2Dp（3） can be uniquely determined by its order components, where p ≠ 2^m ＋ 1 is a prime number, p ≥ 5. more precisely, if OC（G） denotes the set of order components of G, we will prove OC（G） = OC（^2Dp（3）） if and only if G is isomorphic to ^2Dp（3）. A main consequence of our result is the validity of Thompson＇s conjecture for the groups under consideration.

关键词： prime graph order component linear group

Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural regeneration research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity

mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural regeneration research 2025年第3期20卷 805-807页

作者： Josém.Izquierdo Centro de Biología molecular Severo Ochoa(CBm) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

Brain-penetrating neurotrophic factor mimetics: HEr-096 as a disease-modifying therapy for Parkinson’s disease

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Neural regeneration research 2025年第4期20卷 1094-1095页

作者： Natalia Kulesskaya Kira m.Holmström Henri J.Huttunen Herantis Pharma Plc EspooFinland

Neurotrophic factors as a therapeutic approach in neurodegenerative diseases:A major unmet need in the field of central nervous system diseases is disease-modifying *** for decades there have been various symptomatic treatments available to alleviate the symptoms of the disease,disease-modification,*** that stop,significantly delay,or reverse the progression of the disease,has been turned out to a difficult goal to achieve.

关键词： diseases treatment therapeutic

Search for microglia-specific peptides:advances in the discovery toolbox

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Neural regeneration research 2025年第2期20卷 471-472页

作者： Ivan Sarabia Kyle m.Koss Department of Surgery University of ArizonaTucsonAZUSA

Uncontrolled and chronic inflammatory states in the central nervous system(CNS)are the hallmark of neurodegenerative pathology and every injury or stroke-related *** key mediators of these neuroinflammatory states are glial cells known as microglia,the resident immune cell at the core of the inflammatory event,and astroglia,which encapsulate inflammatory insults in proteoglycan-rich scar *** gliotic scar blocks significant portions of healthy axonal networking,preventing *** most neuroinflammation is exclusively based on the responses of said microglia,their phenotypes are suggested to follow those of macrophages;m1 and m2 are opposites of pro-and ***,microglial phenotypes have been identified to be on an inflammatory spectrum encompassing developmental,homeostatic,and reparative behaviors as opposed to their ability to affect devastating cell death cascades and scar tissue formation.

关键词： inflammation pathology death

A new global raster water mask at 250 m resolution

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International Journal of Digital Earth 2009年第4期2卷 291-308页

作者： m.L.Carroll J.r.Townshend C.m.Dimiceli P.Noojipady r.A.Sohlberg Department of Geography University of MarylandCollege Park MDUSA

Accurate depiction of the land and water is critical for the production of land surface parameters from remote sensing data *** parameters,including the land surface temperature,active fires and surface reflectance,can be processed differently when the underlying surface is water as compared with *** errors in the underlying water mask can then pervade into these products and any products created from *** many global databases have been created to depict global surface *** databases still fall short of the current needs of the terrestrial remote sensing community working at 250 m spatial *** most recent attempt to address the problem uses the Shuttle radar Topography mission(SrTm)data set to create the SrTm Water Body Data set(SWBD 2005).The SWBD represents a good first step but still requires additional work to expand the spatial coverage to include the whole globe and to address some erroneous discontinuities in major river *** address this issue a new water mask product has been created using the SWBD in combination with mODIS 250 m data to create a complete global map of surface water at 250 m spatial *** effort is automated and intended to produce a dataset for use in processing of raster data(mODIS and future instruments)and for masking out water in final terrestrial raster data *** new global dataset is produced from remotely sensed data and provided to the public in digital format,free of *** data set can be found on the Global Land Cover Facility(GLCF)website at http://*** dataset is expected to be a base set of information to describe the surface of Earth as either land or water which is a fundamental distinction upon which other descriptions can be made.

关键词： digital earth land cover remote sensing mODIS water

Association of the glycemic background patterns and the diabetes management efficacy in poorly controlled type 2 diabetes

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World Journal of Diabetes 2025年第1期16卷 74-90页

作者： Ayşe N Erbakan müzeyyen Arslan Bahadır FatoşN Kaya Büşra Güleç miraçVural Keskinler Ümmügülsüm AktemurÇelik Özge Faydalıel Banu mesçi Aytekin Oğuz Department of Internal medicine Prof Dr Suleyman Yalcin City HospitalIstanbul Medeniyet UniversityIstanbul 34722Türkiye Department of Family medicine Istanbul Medeniyet UniversityIstanbul 34722Türkiye

BACKGrOUND Inadequate glycemic control in patients with type 2 diabetes(T2Dm)is a major public health problem and a significant risk factor for the progression of diabetic *** To evaluate the effects of intensive and supportive glycemic management strategies over a 12-month period in individuals with T2Dm with glycated hemoglobin(HbA1c)≥10%and varying backgrounds of glycemic *** This prospective observational study investigated glycemic control in patients with poorly controlled T2Dm over 12 *** were categorized into four groups based on prior glycemic history:Newly diagnosed,previously well controlled with recent worsening,previously off-target but now worsening,and HbA1c consistently above 10%.HbA1c levels were monitored quarterly,and patients received medical,educational,and dietary support as *** analysis focused on the success rates of good glycemic control and the associated factors within each *** The study showed significant improvements in HbA1c levels in all *** most significant improvement was observed in individuals newly diagnosed with diabetes:65%achieved an HbA1c target of≤7%.The results varied between participants with different glycemic control histories,followed by decreasing success rates:39%in participants with previously good glycemic control,21%in participants whose glycemic control had deteriorated compared to before,and only 10%in participants with persistently poor control,with mean HbA1c levels of 6.3%,7.7%,8.2%,and 9.7%,*** one year,65.2%of the“newly diagnosed patients”,39.3%in the“previously controlled group”,21.9%in the“previously off-target but now worsened'”group and 10%in the“poorly controlled from the start”group had achieved HbA1c levels of 7 and *** In poorly controlled diabetes,the rate at which treatment goals are achieved is associated with the glycemic background characteristics,emphasizing the need for tailored ***

关键词： Type 2 diabetes mellitus Glycated hemoglobin Glycemic control Patient-centered care Diabetes management glycemic background