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Acute kidney injury in acute-on-chronic liver failure is different from in decompensated cirrhosis

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World Journal of Gastroenterology 2018年第21期24卷 2300-2310页

作者： qun-qun jiang Mei-Fang Han Ke Ma Guang Chen Xiao-Yang Wan Semvua Bukheti Kilonzo Wen-Yu Wu Yong-Li Wang Jie You Qin Ning Department and Institute of Infectious Disease Tongji HospitalTongji Medical CollegeHuazhong University of Science and Technology

AIM To evaluate the differences in acute kidney injury(AKI) between acute-on-chronic liver failure(ACLF) and decompensated cirrhosis(DC) patients. METHODS During the period from December 2015 to July 2017, 280 patients with hepatitis B virus(HBV)-related ACLF(HBV-ACLF) and 132 patients with HBV-related DC(HBV-DC) who were admitted to our center were recruited consecutively into an observational study. Urine specimens were collected from all subjects and the levels of five urinary tubular injury biomarkers were detected,including neutrophil gelatinase-associated lipocalin(NGAL), interleukin-18(IL-18), liver-type fatty acid binding protein(L-FABP), cystatin C(CysC), and kidney injury molecule-1(KIM-1). Simultaneously, the patient demographics, occurrence and progression of AKI, and response to terlipressin therapy were recorded. All patients were followed up for 3 mo or until death after enrollment. RESULTS AKI occurred in 71 and 28 of HBV-ACLF and HBV-DC patients, respectively(25.4% vs 21.2%, P = 0.358). Among all patients, the levels of four urinary biomarkers(NGAL, CysC, L-FABP, IL-18) were significantly elevated in patients with HBV-ACLF and AKI(ACLF-AKI), compared with that in patients with HBV-DC and AKI(DC-AKI) or those without AKI. There was a higher proportion of patients with AKI progression in ACLF-AKI patients than in DC-AKI patients(49.3% vs 17.9%, P = 0.013). Fortythree patients with ACLF-AKI and 19 patients with DC-AKI were treated with terlipressin. The response rate of ACLFAKI patients was significantly lower than that of patients with DC-AKI(32.6% vs 57.9%, P = 0.018). Furthermore, patients with ACLF-AKI had the lowest 90 d survival rates among all groups(P < 0.001).CONCLUSION AKI in ACLF patients is more likely associated with structural kidney injury, and is more progressive, with a poorer response to terlipressin treatment and a worse prognosis than that in DC patients.

关键词： Decompensated cirrhosis Acute-on-chronic liver failure Acute kidney injury Biomarker Etiology Treatment Prognosis

A PARALLEL NONOVERLAPPING DOMAIN DECOMPOSITION METHOD FOR STOKES PROBLEMS

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Journal of Computational Mathematics 2006年第2期24卷 209-224页

作者： Mei-qun jiang Pei-liang Dai Department of Mathematics Suzhou university Suzhou 215006 China Department of Mathematics Changshu Institute of Technology Changshu 215500 China

A nonoverlapping domain decomposition iterative procedure is developed and analyzed for generalized Stokes problems and their finite element approximate problems in R^N（N=2,3）. The method is based on a mixed-type consistency condition with two parameters as a transmission condition together with a derivative-free transmission data updating technique on the artificial interfaces. The method can be applied to a general multi-subdomain decomposition and implemented on parallel machines with local simple communications naturally.

关键词： Generalized Stokes problem Nonoverlapping Domain decomposition Mixedfinite element Crouzeix-Raviart element.

On s-uniform property of compressing sequences derived from primitive sequences modulo odd prime powers

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Science China(Information Sciences) 2017年第5期60卷 84-95页

作者： Yupeng jiang qun-Xiong ZHENG Dongdai LIN State Key Laboratory of Information Security Institute of Information EngineeringChinese Academy of Sciences State Key Laboratory of Mathematical Engineering and Advanced Computing Zhengzhou Information Science and Technology Institute

Let Z/（p;） be the integer residue ring modulo pewith p an odd prime and e 2. We consider the suniform property of compressing sequences derived from primitive sequences over Z/（p;）. We give necessary and sufficient conditions for two compressing sequences to be s-uniform with α provided that the compressing map is of the form φ(x;, x;,..., x;) = g(x;) + η(x;, x;,..., x;), where g(x;) is a permutation polynomial over Z/（p） and η is an（e-1）-variable polynomial over Z/（p）.

关键词： compressing map linear recurring sequence primitive sequence permutation polynomial s uniform

Dynamical behavior of a stochastic multigroup staged-progression HIV model with saturated incidence rate and higher-order perturbations

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International Journal of Biomathematics 2021年第7期14卷 45-83页

作者： qun Liu Daqing jiang Key Laboratory of Applied Statistics of MOE School of Mathenatics and Statistics Northeast Normal University Changchun 130024Jilin ProvinceP.R.China College of Science China University of PetroleumQingdao 266580Shandong ProvinceP.R.China Nonlinear Analysis and Applied Mathematics(NAAM)-Research Group King Abdulaziz University JeddahSaudi Arabia

In this paper,we analyze a higher-order stochastically perturbed multigroup staged-progression model for the transmission of HlV with saturated incidence *** obtainsufficient conditions for the existence and uniqueness of an ergodic stationary distribu-tion of positive solutions to the system by establishing a suitable stochastic *** addition,we make up adequate conditions for complete eradication and wip-ing out the infectious *** a biological interpretation,the existence of a stationarydistribution implies that the disease will prevail and persist in the long ***,examples and numerical simulations are introduced to validate our theoretical results.

关键词： Multigroup HlV model staged progression saturated incidence rate station-ary distribution and ergodicity extinction

Personalized Real-Time Movie Recommendation System:Practical Prototype and Evaluation

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Tsinghua Science and Technology 2020年第2期25卷 180-191页

作者： jiang Zhang Yufeng Wang Zhiyuan Yuan qun Jin Nanjing University of Posts and Telecommunications(NUPT) Nanjing 210003China Networked Information Systems Laboratory Department of Human Informatics and Cognitive SciencesFaculty of Human SciencesWaseda UniversityTokyo 163-8001Japan

With the eruption of big data,practical recommendation schemes are now very important in various fields,including e-commerce,social networks,and a number of web-based ***,there exist many personalized movie recommendation schemes utilizing publicly available movie datasets(e.g.,MovieLens and Netflix),and returning improved performance metrics(e.g.,Root-Mean-Square Error(RMSE)).However,two fundamental issues faced by movie recommendation systems are still neglected:first,scalability,and second,practical usage feedback and verification based on real *** particular,Collaborative Filtering(CF)is one of the major prevailing techniques for implementing recommendation ***,traditional CF schemes suffer from a time complexity problem,which makes them bad candidates for real-world recommendation *** this paper,we address these two ***,a simple but high-efficient recommendation algorithm is proposed,which exploits users1 profile attributes to partition them into several *** each cluster,a virtual opinion leader is conceived to represent the whole cluster,such that the dimension of the original useritem matrix can be significantly reduced,then a Weighted Slope One-VU method is designed and applied to the virtual opinion leader-item matrix to obtain the recommendation *** to traditional clusteringbased CF recommendation schemes,our method can significantly reduce the time complexity,while achieving comparable recommendation ***,we have constructed a real personalized web-based movie recommendation system,MovieWatch,opened it to the public,collected user feedback on recommendations,and evaluated the feasibility and accuracy of our system based on this real-world data.

关键词： movie recommendation system collaborative filtering real-time virtual opinion leader data mining

Microcos paniculata: a review on its botany, traditional uses, phytochemistry and pharmacology

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Chinese Journal of Natural Medicines 2019年第8期17卷 561-574页

作者： jiang Ying-qun LIU E-Hu State Key Laboratory of Natural Medicines China Pharmaceutical University

The shrub Microcos paniulata(MPL;Tiliaceae), distributed in south China, south and southeast Asia, yields a phytomedicine used to treat heat stroke, fever, dyspepsia, diarrhea, insect bites and jaundice. Phytochemical investigations on different parts of MPL indicate the presence of flavonoids, alkaloids, triterpenoids and organic acids. The MPL leaves, fruits, barks and roots extracts showed antidiarrheal, antimicrobial and insecticidal, anti-inflammation, hepatoprotective, cardiovascular protective, blood lipids reducing, analgesic, jaundice-relieving and antipyretic activities, etc. The review aims to summary the traditional uses, botany,phytochemistry, pharmacological bioactivity, quality control, toxicology and potential mechanisms of MPL. Additionally, this review will highlight the existing research gaps in knowledge and provide a foundation for further investigations on this plant.

关键词： Microcos paniculata Botany Traditional uses Phytochemistry Pharmacology

L^(p)-solutions of Multi-dimensional Oblique Reflected BSDEs and Optimal Switching Problem on Finite or Infinite Time Horizon

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Acta Mathematicae Applicatae Sinica 2024年第4期40卷 1127-1146页

作者： Xue-jun SHI qun FENG Long jiang School of Mathematics and Statistics Shandong Normal UniversityJinan 250358China School of Management Science and Engineering University of JinanJinan 250002China School of Mathematics China University of Mining and TechnologyXuzhou 221116China

In this paper,we study mulit-dimensional oblique reflected backward stochastic differential equations(RBSDEs)in a more general framework over finite or infinite time horizon,corresponding to the pricing problem for a ... 详细信息

关键词： multi-dimensional oblique reflected BSDE optimal switching and stopping problem finite or infinite time horizon uniformly continuous generators

Variable stiffness design of redundantly actuated planar rotational parallel mechanisms

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Chinese Journal of Aeronautics 2017年第2期30卷 818-826页

作者： Li Kangkang jiang Hongzhou Cui Zuo Huang qun School of Mechatronics Engineering Harbin Institute of Technology Harbin 150001 China

Redundantly actuated planar rotational parallel mechanisms（RAPRPMs） adapt to the requirements of robots under different working conditions by changing the antagonistic internal force to tune their *** geometrical parameters of the mechanism impact the performances of modulating *** expressions relating stiffness and geometrical parameters of the mechanism were formulated to obtain the necessary conditions of variable stiffness.A novel method of variable stiffness design was presented to optimize the geometrical parameters of the *** stiffness variation with the internal force was *** dynamic change of stiffness with the dynamic location of the mechanism was minimized,and the robustness of stiffness during the motion of the mechanism was *** new approach to variable stiffness design can enable off-line planning of the internal force to avoid the difficulties of on-line control of the internal force.

关键词： Internal force Parallel mechanisms Redundantly actuated Robustness Variable stiffness

A survey of deep learning-based 3D shape generation

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Computational Visual Media 2023年第3期9卷 407-442页

作者： qun-Ce Xu Tai-jiang Mu Yong-Liang Yang BNRist Department of Computer Science and TechnologyTsinghua UniversityBeijing 100084China Department of Computer Science University of BathBathUK

Deep learning has been successfully used for tasks in the 2D image *** on 3D computer vision and deep geometry learning has also attracted *** achievements have been made regarding feature extraction and discrimination of 3D *** recent advances in deep generative models such as generative adversarial networks,effective generation of 3D shapes has become an active research *** 2D images with a regular grid structure,3D shapes have various representations,such as voxels,point clouds,meshes,and implicit *** deep learning of 3D shapes,shape representation has to be taken into account as there is no unified representation that can cover all tasks *** such as the representativeness of geometry and topology often largely affect the quality of the generated 3D *** this survey,we comprehensively review works on deep-learning-based 3D shape generation by classifying and discussing them in terms of the underlying shape representation and the architecture of the shape *** advantages and disadvantages of each class are further *** also consider the 3D shape datasets commonly used for shape ***,we present several potential research directions that hopefully can inspire future works on this topic.

关键词： 3D representations geometry learning generative models deep learning