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Applied Mathematics and Mechanics(English Edition) 2015年第3期36卷 329-336页

作者： qun han Wei XU Xiaole YUE Department of Applied Mathematics Northwestern Polytechnical University

The stochastic response of a noisy system with non-negative restoring force is investigated. The generalized cell mapping （GCM） method compute the transient and stationary probability density functions （PDFs） real-power is used to Combined with the global properties of the noise-free system, the evolutionary process of the tran- sient PDFs is revealed. The results show that stochastic P-bifurcation occurs when the system parameter varies in the response analysis and the stationary PDF evolves from bimodal to unimodal along the unstable manifold during the bifurcation.

关键词： stochastic response probability density function (PDF) generalized cell mapping (GCM) method real-power restoring force bifurcation

基于GIS的城市房屋建筑双违清查系统设计与实现

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测绘与空间地理信息 2024年第7期47卷 96-98,101页

作者：王鹏韩群王雅楠济南市房产测绘研究院山东济南250001

依据《山东省住房和城乡建设厅关于进一步做好城市房屋建筑违法建设和违法违规审批专项清查工作的通知》等文件的要求,结合济南市智慧住建建设的实际情况,依托GIS,设计并开发一套具有地图浏览、数据批量导入、图属关联、地图定位、专题... 详细信息

依据《山东省住房和城乡建设厅关于进一步做好城市房屋建筑违法建设和违法违规审批专项清查工作的通知》等文件的要求,结合济南市智慧住建建设的实际情况,依托GIS,设计并开发一套具有地图浏览、数据批量导入、图属关联、地图定位、专题图进度查看等功能的专项清查系统,为城市房屋建筑违法建设和违法违规审批专项清查工作提供技术支撑。

关键词：城市房屋专项清查 GIS 专题数据

Current treatment of chronic hepatitis C in China: Dilemma and potential problems

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World Journal of Gastroenterology 2016年第19期22卷 4615-4618页

作者： qun-Ying han Zheng-Wen Liu Department of Infectious Diseases First Affiliated Hospital of Xi’an Jiaotong University

Major advances have been made in the treatment of chronic hepatitis C virus(HCV) infection with the advent of direct-acting antiviral agents(DAAs). China has the most cases of HCV infection worldwide, but none of the DAAs has been approved in China's Mainland so far, and interferon(IFN)-α-based treatment remains the standard of care. HCV patients without response or with contraindications to IFN-based therapy have no alternative options. However, many patients buy DAAs, especially the generic forms of sofosbuvir, from other countries or areas. Under these circumstances, the use of these drugs may cause many predictable and unpredictable problems in ethics, law and medical practice. Given the obstacles of legal accessibility to DAAs and the potential problems of obtaining and using DAAs in China, the early launching of the DAAs in China or the legalization of buying drugs from areas outside China and using these drugs in China is an urgent issue and needs to be dealt with as soon as possible, in the interest of the patients.

关键词： Hepatitis C virus infection Treatment Direct-acting antiviral agent Generics China

基于济南“智慧住建”的既有房屋建筑安全信息管理平台的设计与实现

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中国建设信息化 2024年第16期 86-90页

作者：汪红梅李春光韩群济南市房产测绘研究院

由于房屋自然老化、安全管理不到位等原因,近年来房屋使用安全隐患日益凸显。本文立足济南市房屋安全管理现状,以“智慧住建”大数据中心汇集的海量房屋信息、房屋普查信息、住建业务信息、住建一张图为数据支撑,以房屋安全管理为主线,... 详细信息

由于房屋自然老化、安全管理不到位等原因,近年来房屋使用安全隐患日益凸显。本文立足济南市房屋安全管理现状,以“智慧住建”大数据中心汇集的海量房屋信息、房屋普查信息、住建业务信息、住建一张图为数据支撑,以房屋安全管理为主线,按照“一库、两端、四子系统”的建设规划,打造结构优化、资源整合、高效便捷的既有房屋建筑安全管理信息平台,突破房屋安全传统管理模式,提高房屋安全的管理效率。

关键词：房屋安全平台建设以图管房

Optimal design of Er/Yb co-doped fiber amplifiers with an Yb-band fiber Bragg grating

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Photonics Research 2016年第2期4卷 53-56页

作者： qun han Wenchuan Yan Yunzhi Yao Yaofei Chen Tiegen Liu College of Precision Instrument and Opto-Electronics Engineering Tianjin University Key Lab of Opto-Electronics Information Technology (Tianjin University) Ministry of Education

In this paper, Er/Yb co-doped fiber amplifiers(EYDFAs) with an Yb-band fiber Bragg grating(FBG) at the pump end to improve the performance of the amplifier is systematically studied. The influence of the reflectivity and center wavelength of the FBG along with the gain-fiber length on the performance of an EYDFA are numerically analyzed. The results show that the wavelength of the FBG has critical influence on the efficiency of the EYDFA,whereas the requirement to its reflectivity is relaxed. It is an effective and promising way to improve the efficiency of a high-power pumped EYDFA by introducing a suitable Yb-band FBG at the pump end. Based on the analysis of the underlying principles, suggestions for the practical design and possible further improvement strategies are also proposed.

关键词： FBG Yb Optimal design of Er/Yb co-doped fiber amplifiers with an Yb-band fiber Bragg grating

Curcumin Recovers Intracellular Lipid Droplet Formation Through Increasing Perilipin 5 Gene Expression in Activated Hepatic Stellate Cells In Vitro

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Current Medical Science 2019年第5期39卷 766-777页

作者： Xiao-qun han San-qing XU Jian-guo LIN Department of Microbiology and Immunology Medical College of Yichun UniversityYichun 336000China Department of Pediatrics Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China P3 Biosafety Laboratory Guangdong Second Provincial General HospitalGuangzhou 510317China Affiliated Nanyue Hospital Southern Medical UniversityGuangzhou 510317China

The activation of hepatic stellate cells(HSCs)is a major event during hepatic *** of intracellular lipid droplet(LD)formation turns the activated HSC back to a quiescent *** previous studies have shown that curcumin suppresses HSC activation through increasing peroxisome proliferator-activated receptor,gamma(PPARγ)and 5′adenosine monophosphate-activated protein kinase(AMPK)*** study aims at evaluating the effect of curcumin on lipid accumulation in HSCs and hepatocytes,and further elucidating the underlying *** we showed that curcumin increased LD formation in activated HSCs and stimulated the expression of sterol regulatory element-binding protein and fatty acid synthase,and reduced the expression of adipose triglyceride *** perilin5 expression in primary HSCs promoted LD *** 5 siRNA eliminated curcumin-induced LD formation in *** results suggest that curcumin recovers LD formation and lipid accumulation in activated HSCs by increasing perilipin 5 gene ***,inhibition of AMPK or PPARy activity blocked curcumin's effect on Plin5 gene expression and LD *** results provide a novel evidence in vitro for curcumin as a safe,effective candidate to treat liver fibrosis.

关键词： hepatic stellate cells lipid droplets perilipins curcumin liver fibrosis

Lattice Boltzmann simulation on thermal performance of composite phase change material based on Voronoi models

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Chinese Physics B 2021年第10期30卷 383-393页

作者： Meng-Yue Guo qun han Xiang-Dong Liu Bo Zhou Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education School of Energy and EnvironmentSoutheast UniversityNanjing 210096China College of Electrical Energyand Power EngineeringYangzhou UniversityYangzhou 225127China Jiangsu Key Laboratory of Micro and Nano Heat Fluid Flow Technology and Energy Application School of Environmental Science and EngineeringSuzhou University of Science and TechnologySuzhou 215009China

Phase change materials(PCMs)are important for sustaining energy *** the thermal performance enhancement,the composite PCM with metal foam reconstructed by the Voronoi method is investigated in this *** lattice Boltzmann method(LBM)is used to analyze the melting process on a pore *** melting interface evolution and temperature contour of the composite PCM are explored and compared with those of pure ***,structure parameters including the pore density,porosity and irregularity are investigated comprehensively,indicating that the additive of metal foam strengthens the melting performance of PCM *** with pure PCM,the composite PCM has quick rates of the melting front evolution and heat *** heat conduction plays a great role in the whole melting process since the convection is weakened for the composite *** improve the melting efficiency,a larger pore density and smaller irregularity are recommended in *** significantly,a suitable porosity is determined based on the requirement for the balance between the melting rate and heat storage capacity in practical engineering.

关键词： metal foam Voronoi melting heat transfer enhancement

大学生创新创业项目管理探索——以东北林业大学林业工程类一流专业为例

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大学（研究与管理） 2024年第4期 189-192页

作者：陈百灵韩群谢圣玉东北林业大学材料科学工程学院黑龙江哈尔滨150000 东北林业大学数字化建设处黑龙江哈尔滨150000 东北林业大学本科生院黑龙江哈尔滨150000

随着经济的发展,创新创业教育的重要性日益显著。大学生创新创业项目数量日益增多。文章针对大学生创新创业项目管理进行研究,旨在提高大学生创新创业项目成果质量、提高学生创新创业兴趣。创新创业项目管理以学生为主体,教师进行指导,... 详细信息

随着经济的发展,创新创业教育的重要性日益显著。大学生创新创业项目数量日益增多。文章针对大学生创新创业项目管理进行研究,旨在提高大学生创新创业项目成果质量、提高学生创新创业兴趣。创新创业项目管理以学生为主体,教师进行指导,通过日常管理、过程管理,将课程思政、劳动教育融入学生培养各个环节,并提供制度保障、平台保障、机构保障,实现创新创业教育高质量发展。

关键词：大学生项目创新创业项目管理

基于引擎式开发的城中村改造数字化平台的设计与实现

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中国建设信息化 2024年第1期 80-83页

作者：陈艳华王迪韩群李春光济南市房产测绘研究院济南市城乡建设发展服务中心

城中村作为城市化的产物,既是城市发展所面临的问题,又是城市发展的机遇。为有效提升城市品质、改善居民生活条件、推动城市经济发展,开展城中村改造工作势在必行。本文立足于济南市城市发展水平和城中村改造工作开展现状,基于济南市“... 详细信息

城中村作为城市化的产物,既是城市发展所面临的问题,又是城市发展的机遇。为有效提升城市品质、改善居民生活条件、推动城市经济发展,开展城中村改造工作势在必行。本文立足于济南市城市发展水平和城中村改造工作开展现状,基于济南市“智慧住建”成果,构建了济南市城中村改造数字化平台,建设了城中村改造时空数据中心、项目库管理、全生命周期管理和城中村改造一张图等功能,满足了城中村改造工作的业务支撑、综合监管、辅助决策、社会服务等多样化需求,为稳步推动城中村改造工作、推动城市高质量发展提供了有力支撑。

关键词：城中村改造智慧住建引擎式开发矢量瓦片

亚洲柑橘木虱对两种寄主植物嫩芽及其挥发物的行为反应

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环境昆虫学报 2024年第2期46卷 498-505页

作者：高萌鸽谢鹏何嘉伟何青翠叶梓栋韩群鑫仲恺农业工程学院植物健康研究院/农业农村部华南果蔬绿色防控重点实验室/广东省普通高校果蔬病虫害绿色防控重点实验室广州510225

亚洲柑橘木虱Diaphorina citri Kuwayama是柑橘嫩梢期的重要害虫,也是柑橘黄龙病的传播媒介。本文采用顶空固相微萃取和气质联用技术(GC-MS)测定了九里香Murraya exotica L.、砂糖橘Citrus reticulate cv. Shatangju不同发育状态嫩芽的... 详细信息

亚洲柑橘木虱Diaphorina citri Kuwayama是柑橘嫩梢期的重要害虫,也是柑橘黄龙病的传播媒介。本文采用顶空固相微萃取和气质联用技术(GC-MS)测定了九里香Murraya exotica L.、砂糖橘Citrus reticulate cv. Shatangju不同发育状态嫩芽的挥发性成分,并利用四臂嗅觉仪测定了亚洲柑橘木虱成虫对九里香和砂糖橘嫩芽中的4种共有挥发性成分葎草烯、正己醛、石竹烯、反式-2-己烯醛的趋性反应,从行为学反应和化学成分等方面深入研究了亚洲柑橘木虱和寄主植物挥发物的关系,以期探究植物源气味在亚洲柑橘木虱寄主选择中的作用。结果表明:(1)砂糖橘未展开嫩芽、半展开嫩芽分别含有36种、41种挥发性物质,全展开嫩芽和新叶分别含有32种和37种挥发性物质,九里香未展开嫩芽和展开嫩芽分别含有20种和14种挥发性物质;(2)两种植物不同发育状态嫩芽的共有挥发物有8种,分别是葎草烯、正己醛、石竹烯、反式-2-己烯醛、[S-(E,E)]-1-乙基-5-亚甲基-8-(1-甲基乙基)-1,6-环癸二烯、α-荜澄茄油烯、γ-芹子烯和δ-杜松烯;(3)亚洲柑橘木虱成虫对10μL/mL石竹烯、100μL/mL反式-2-己烯醛以及1μL/mL葎草烯有明显的正趋性,研究结果可为亚洲柑橘木虱引诱剂的开发提供依据。

关键词：亚洲柑橘木虱寄主选择植物挥发物行为反应