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Grain refinement of Mg-Ca alloys by native MgO particles

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Journal of Magnesium and Alloys 2024年第3期12卷 980-996页

作者： Shihao Wang Yun Wang quentin M.Ramasse Zhongyun Fan Super STEM Laboratory SciTech Daresbury CampusDaresbury WA44ADUK School of Chemical and Process Engineering University of LeedsLeeds LS29JTUK BCAST Brunel University LondonUxbridgeMiddlesex UB83PHUK

In Mg-Ca alloys the grain refining mechanism,in particular regarding the role of nucleant substrates,remains the object of *** native MgO is being recognised as a nucleating substrate accounting for grain refinement of Mg alloys,the possible interactions of MgO with alloying elements that may alter the nucleation potency have not been elucidated ***,we design casting experiments of Mg-xCa alloys varied qualitatively in number density of native MgO,which are then comprehensively studied by advanced electron *** results show that grain refinement is enhanced as the particle number density of MgO *** native MgO particles are modified by interfacial layers due to the co-segregation of Ca and N solute atoms at the MgO/Mg *** aberration-corrected scanning transmission electron microscopy and electron energy loss spectroscopy,we reveal the nature of these Ca/N interfacial layers at the atomic *** of the crystallographic termination of MgO,Ca and N co-segregate at the MgO/Mg interface and occupy Mg and O sites,respectively,forming an interfacial structure of a few atomic *** interfacial structure is slightly expanded,less ordered and defective compared to the MgO matrix due to compositional deviations,whereby the MgO substrate is altered as a poorer template to nucleate Mg *** solidification in a TP-1 mould,the impotent MgO particles account for the grain refining mechanism,where they are suggested to participate into nucleation and grain initiation processes in an explosive *** work not only reveals the atomic engineering of a substrate through interfacial segregation but also demonstrates the effectiveness of a strategy whereby native MgO particles can be harnessed for grain refinement in Mg-Ca alloys.

关键词： Mg-Ca alloy Grain refinement MgO Interfacial segregation STEM/EELS Solidification.

Rapid profiling rock mass quality underneath tunnel face for Sichuan-Xizang Railway

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Underground Space 2024年第6期19卷 138-152页

作者： Siyuan Wu Min Qiu Zhao Yang Fuquan Ji Zhongqi quentin Yue Department of Civil Engineering The University of Hong KongHong Kong 999077China CCCC Second Harbor Engineering Company Ltd. Wuhan 430000China Research and Development Center of Transport Industry of Intelligent Manufacturing Technologies of Transport Infrastructure Wuhan 430000China

The Sichuan-Xizang Railway is a global challenge,surpassing other known railway projects in terms of geological and topographical *** paper presents an approach for rapidly profiling rock mass quality underneath tunnel face for the ongoing construction of the Sichuan-Xizang *** adopts the time-series method and carries out the quantitative analysis of the rock mass quality using the depth-series measurement-while-drilling(MWD)data associated with drilling of blastholes.A tunnel face with 15 blastholes is examined for *** results include identification of the boundary of homogeneous geomaterial by plotting the blasthole depth against the net drilling time,as well as quantification of rock mass quality through the recalculation of the new specific *** new specific energy profile is compared and highly consistent with laboratory test,manual logging and tunnel seismic prediction *** consistency can enhance the blasthole pattern design and facilitate the dynamic determination of charge placement and *** paper highlights the importance of digital monitoring during blasthole drilling for rapidly profiling rock mass quality underneath and ahead of tunnel *** upgrades the MWD technique for rapid profiling rock mass quality in drilling and blasting tunnels.

关键词： Measurement-while-drilling Drilling and blasting Rock mass quality New specific energy Constant penetration rate Sichuan-Xizang railway Tunnelling

Extended wet sieving method for determination of complete particle size distribution of general soils

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第1期16卷 242-257页

作者： Shengnan Ma Yi Song Jiawei Liu Xingyu Kang Zhongqi quentin Yue Department of Civil Engineering The University of Hong KongHong KongChina

The traditional standard wet sieving method uses steel sieves with aperture?0.063 mm and can only determine the particle size distribution(PSD)of gravel and sand in general *** paper extends the traditional method and presents an extended wet sieving *** extended method uses both the steel sieves and the nylon filter cloth *** apertures of the cloth sieves are smaller than 0.063 mm and equal 0.048 mm,0.038 mm,0.014 mm,0.012 mm,0.0063 mm,0.004 mm,0.003 mm,0.002 mm,and 0.001 mm,*** extended method uses five steps to separate the general soil into many material sub-groups of gravel,sand,silt and clay with known particle size *** complete PSD of the general soil is then calculated from the dry masses of the individual material *** extended method is demonstrated with a general soil of completely decomposed granite(CDG)in Hong Kong,*** silt and clay materials with different particle size ranges are further examined,checked and verified using stereomicroscopic observation,physical and chemical property *** results further confirm the correctness of the extended wet sieving method.

关键词： Particle size distribution(PSD) General soil Silt Clay Wet sieving Physical and chemical properties

Digital monitoring of rotary-percussive drilling with down-the-hole hammer for profiling weathered granitic ground

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第5期16卷 1615-1636页

作者： Wendal Victor Yue Siyuan Wu Manchao He Yafei Qiao Zhongqi quentin Yue Department of Geotechnical Engineering College of Civil EngineeringTongji UniversityShanghai200092China Department of Civil Engineering Faculty of EngineeringThe University of Hong KongPokfulam RoadHong KongChina State Key Laboratory for Geomechanics and Deep Underground Engineering China University of Mining and TechnologyBeijing100083China Key Laboratory of Geotechnical and Underground Engineering of Ministry of Education Tongji UniversityShanghai200092China

Rock and geotechnical engineering investigations involve drilling holes in ground with or without retrieving soil and rock samples to construct the subsurface ground *** the basis of an actual soil nailing drilling for a slope stability project in Hong Kong,this paper further develops the drilling process monitoring(DPM)method for digitally profiling the subsurface geomaterials of weathered granitic rocks using a compressed airflow driven percussive-rotary drilling machine with down-the-hole(DTH)*** transducers are installed on the drilling machine and record the chuck displacement,DTH rotational speed,and five pressures from five compressed airflows in real-time *** mechanism and operations of the drilling machine are elaborated in detail,which is essential for understanding and evaluating the drilling data.A MATLAB program is developed to automatically filter the recorded drilling data in time series and classify them into different drilling processes in sub-time *** processes include penetration,push-in with or without rod,pull-back with or without rod,rod-tightening and *** drilling data are further reconstructed to plot the curve of drill-bit depth versus the net drilling time along each of the six *** curve is found to contain multiple linear segments with a constant penetration rate,which implies a zone of homogenous geomaterial with different weathering *** effect from fluctuation of the applied pressures is evaluated *** analyses are presented for accurately assess and verify the underground profiling and strength in weathered granitic rock,which provided the basis of using DPM method to confidently assess drilling measurements to interpret the subsurface profile in real time.

关键词： Drilling process monitoring(DPM) Down-the-hole(DTH)hammer Percussive-rotary drilling Weathering granitic rocks

Tree species identity and interaction determine vertical forest structure in young planted forests measured by terrestrial laser scanning

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Forest Ecosystems 2024年第3期11卷 266-275页

作者： Mengxi Wang Lander Baeten Frieke Van Coillie Kim Calders Kris Verheyen quentin Ponette Haben Blondeel Bart Muys John Armston Hans Verbeeck Q-ForestLab Department of EnvironmentFaculty of Bioscience EngineeringGhent UniversityBelgium Forest&Nature Lab Department of EnvironmentFaculty of Bioscience EngineeringGhent UniversityBelgium Earth and Life Institute Université Catholique de Louvain(UCLouvain)Louvain-la-NeuveBelgium Department of Earth&Environmental Sciences KU LeuvenBelgium Department of Geographical Sciences University of MarylandCollege ParkMDUSA

Vertical forest structure is closely linked to multiple ecosystem characteristics,such as biodiversity,habitat,and *** tree species in planted forests has the potential to create diverse vertical forest structures due to the different physiological and morphological traits of the composing tree ***,the relative importance of species richness,species identity and species interactions for the variation in vertical forest structure remains unclear,mainly because traditional forest inventories do not observe vertical stand structure in *** laser scanning(TLS),however,allows to study vertical forest structure in an unprecedented ***,we used TLS single scan data from 126 plots across three experimental planted forests of a largescale tree diversity experiment in Belgium to study the drivers of vertical forest *** plots were 9–11years old young pure and mixed forests,characterized by four levels of tree species richness ranging from monocultures to four-species mixtures,across twenty composition *** generated vertical plant profiles from the TLS data and derived six stand structural *** mixed models were used to test the effect of species richness on structural *** a hierarchical diversity interaction modelling framework,we further assessed species identity effect and various species interaction effects on the six stand structural *** results showed that species richness did not significantly influence most of the stand structure variables,except for canopy height and foliage height *** identity on the other hand exhibited a significant impact on vertical forest structure across all *** interaction effects were observed to be site-dependent due to varying site conditions and species pools,and rapidly growing tree species tend to dominate these ***,our results highlighted the importance of considering both species identity an

关键词： TreeDivNet FORBIO Stand structural complexity Terrestrial laser scanning Vertical forest structure Tree diversity Planted forests

The root-knot nematode effectorMi2G02 hijacks a host plant trihelix transcription factor to promote nematode parasitism

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Plant Communications 2024年第2期5卷 151-168页

作者： Jianlong Zhao Kaiwei Huang Rui Liu Yuqing Lai Pierre Abad Bruno Favery Heng Jian Jian Ling Yan Li Yuhong Yang Bingyan Xie Michael quentin Zhenchuan Mao State Key Laboratory of Vegetable Biobreeding Institute of Vegetables and FlowersChinese Academy of Agricultural SciencesBeijing 100081China INRAE Universite´Cote d’AzurCNRSISA06903 Sophia AntipolisFrance Department of Plant Pathology and Key Laboratory of Pest Monitoring and Green Management of the Ministry of Agriculture China Agricultural UniversityBeijing 100193China

Root-knot nematodes(RKNs)cause huge agricultural losses every *** secrete a repertoire of effectors to facilitate parasitism through the induction of plant-derived giant feeding cells,which serve as their sole source of ***,the mode of action of these effectors and their targeted host pro-teins remain largely *** this study,we investigated the role of the effector Mi2G02 in Meloidogyne incognita ***-derived Mi2G02 RNA interference in Arabidopsis thaliana affected giant cell development,whereas ectopic expression of Mi2G02 promoted root growth and increased plant sus-ceptibility to *** used various combinations of approaches to study the specific interactions between Mi2G02 and *** GT-3a,a trihelix transcription ***-3a knockout in *** affected feeding-site development,resulting in production of fewer egg masses,whereas GT-3a overex-pression in *** increased susceptibility to *** and also root ***,we demon-strated that Mi2G02 plays a role in maintaining GT-3a protein stabilization by inhibiting the 26S proteasome-dependent pathway,leading to suppression of TOZ and RAD23C expression and thus promoting nematode *** work enhances our understanding of how a pathogen effector manipulates the role and regulation of a transcription factor by interfering with a proteolysis pathway to reprogram gene expression for development of nematode feeding cells.

关键词： Meloidogyne incognita effector giant cell Mi2G02 transcription factor interaction

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可以放在鞋盒中的数据中心

科技纵览 2024年第6期 38-43,4页

作者： Anna Herr quentin Herr Imec

比利时微电子研究中心计划利用超导缩小计算机。科学家预测,到2040年,计算消耗的电力将占全球总量的50%。这一预测是在生成式人工智能爆发之前作出的。过去十多年来,训练大型人工智能模型所需的计算资源大约每6个月就会翻一番。按照这... 详细信息

比利时微电子研究中心计划利用超导缩小计算机。科学家预测,到2040年,计算消耗的电力将占全球总量的50%。这一预测是在生成式人工智能爆发之前作出的。过去十多年来,训练大型人工智能模型所需的计算资源大约每6个月就会翻一番。按照这个速度,到2030年,训练一个人工智能模型所需的计算资源将是当前十大超级计算机年度所需资源之和的100倍。简而言之,计算需要的巨大电力能源,很快将超出地球所能提供的范围。

关键词：数据中心超级计算机人工智能计算资源电力能源微电子生成式计算消耗

Microbiota enterotoxigenic Bacteroides fragilis-secreted BFT-1 promotes breast cancer cell stemness and chemoresistance through its functional receptor NOD1

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Protein & Cell 2024年第6期15卷 419-440页

作者： Wei Ma Lu Zhang Weilong Chen Zhaoxia Chang Juchuanli Tu Yuanyuan Qin Yuwen Yao Mengxue Dong Jiajun Ding Siqin Li Fengkai Li Qiaodan Deng Yifei Yang Tingting Feng Fanrong Zhang Xiying Shao Xueyan He Lixing Zhang Guohong Hu quentin Liu Yi-Zhou Jiang Shu Zhu Zhi Xiao Dan Su Tong Liu Suling Liu Fudan University Shanghai Cancer Center & Institutes of Biomedical Sciences State Key Laboratory of Genetic EngineeringCancer InstitutesDepartment of OncologyKey Laboratory of Breast Cancer in ShanghaiThe Shanghai Key Laboratory of Medical EpigeneticsShanghai Key Laboratory of Radiation OncologyThe International Co-laboratory of Medical Epigenetics and MetabolismMinistry of Science and TechnologyShanghai Medical CollegeFudan UniversityShanghai 200032China Intelligent Pathology Institute and Department of Pathology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230071China Department of Thyroid Breast and Vascular SurgeryXijing HospitalFourth Military Medical UniversityXi’an 710032China Institute of Immunology CAS Key Laboratory of Innate Immunity and Chronic DiseaseSchool of Basic Medical SciencesDivision of Life Science and MedicineUniversity of Science and Technology of ChinaHefei 230027China Department of Pathology The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)Institute of Basic Medicine and Cancer (IBMC)Chinese Academy of SciencesHangzhou 310022China Department of Breast Surgery The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)Institute of Basic Medicine and Cancer (IBMC)Chinese Academy of SciencesHangzhou 310022China Department of Breast Medical Oncology The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)Institute of Basic Medicine and Cancer (IBMC)Chinese Academy of SciencesHangzhou 310022China Shanghai Institute of Nutrition and Health University of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaGuangzhou 510060China Department of Breast Surgery Xiangya HospitalChangsha 410008China Department of Breast Surgery Tumor Hospital of Harbin Medic

Tumor-resident microbiota in breast cancer promotes cancer initiation and malignant ***,targeting microbiota to improve the effects of breast cancer therapy has not been investigated in ***,we evaluated the microbiota composition of breast tumors and found that enterotoxigenic Bacteroides fragilis(ETBF)was highly enriched in the tumors of patients who did not respond to taxane-based neoadjuvant ***,albeit at low biomass,secreted the toxic protein BFT-1 to promote breast cancer cell stemness and *** studies showed that BFT-1 directly bound to NOD1 and stabilized NOD1 ***1 was highly expressed on ALDH+breast cancer stem cells(BCSCs)and cooperated with GAK to phosphorylate NUMB and promote its lysosomal degradation,thereby activating the NOTCH1-HEY1 signaling pathway to increase ***1 inhibition and ETBF clearance increase the chemosensitivity of breast cancer by impairing BCSCs.

关键词： NOD1 breast chemotherapy

Yue＇s solution of classical elasticity in n-layered solids： Part 2, mathematical verification

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Frontiers of Structural and Civil Engineering 2015年第3期9卷 250-285页

作者： Zhong-qi quentin YUE Department of Civil Engineering The University of Hong Kong Hong Kong China

This paper presents a detailed and rigorous mathematical verification of Yue＇s approach, Yue＇s treatment, Yue＇s method and Yue＇s solution in the companion paper for the classical theory of elasticity in n-layered solid. It involves three levels of the mathematical verifications, The first level is to show that Yue＇s solution can be automatically and uniformly degenerated into these classical solutions in closed-form such as Kelvin＇s, Boussinesq＇s, Mindlin＇s and bi- material＇s solutions when the material properties and boundary conditions are the same. This mathematical verification also gives and serves a clear and concrete understanding on the mathematical properties and singularities of Yue＇s solution in n-layered solids. The second level is to analytically and rigorously show the convergence and singularity of the solution and the satisfaction of the solution to the governing partial differential equations, the interface conditions, the external boundary conditions and the body force loading conditions. This verification also provides the easy and executable means and results for the solutions in n-layered or graded solids to be calculated with any controlled accuracy in association with classical numerical integration techniques. The third level is to demonstrate the applicability and suitability of Yue＇s approach, Yue＇s treatment, Yue＇s method and Yue＇s solution to uniformly and systematically derive and formulate exact and complete solutions for other boundary-value problems, mixed-boundary value problems, and initial-boundary value problems in layered solids in the frameworks of classical elasticity, boundary element methods, elastodynamics, Biot＇s theory of poroelasticity and thermoelasticity. All of such applications are substantiated by peer- reviewed journal publications made by the author and his collaborators over the past 30 years.

关键词： elasticity boundary element method elastodynamics poroelasticity thermoelasticity