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Journal of Environmental Sciences 2024年第3期137卷 321-332页

作者： Yong-Li Cai Yu-Hang Xu Ji-Zun xiang Zhi-Qiang Zhang qiu-xiang he Ya-Feng Li Jian Lü Fujian Provincial Key Laboratory of Soil Environmental health and Regulation College of Resources and EnvironmentFujian Agriculture and Forestry UniversityFuzhou 350002China State Key Laboratory of Photocatalysis on Energy and Environment Fuzhou UniversityFuzhou 350116China

Pesticides and its degradation products,being well–known residues in soil,have recently been detected in many water bodies as pollutants of emerging concerns,and thus there is a contemporary demand to develop viable and cost–effective techniques for the removal of related organic pollutants in aqueous ***,a visible-light-responsive Fenton system was constructed with iron–doped bismuth oxybromides(Fe–BiOBr)as the *** the advantage of sustainable Fe(Ⅲ)/Fe(Ⅱ)conversion and optimized H_(2)O_(2)utilization,the optimal Fe–BiOBr–2 catalyst showed an excellent atrazine removal efficiency of 97.61%in 120 min,which is superior than the traditional homogeneous Fenton and the majority of heterogeneous processes documented in the *** this photo–Fenton system,hydroxyl(·OH)and superoxide(·O_(2)^(-))radicals were dominant active species contributed to the oxidative degradation of *** to the production of various active radicals,five degradation pathways were proposed based on the identification of intermediates and degradation ***,this work not only demonstrates a fundamental insight into creating highly efficient and atom economic photo-Fenton systems,but also provides a complementary strategy for the treatment of organic pollutants in water.

关键词： Bismuth oxybromide Photo–Fenton Atrazine Catalytic degradation

Exploring the Pathogenesis of Autoimmune Liver Diseases from the heterogeneity of Target Cells

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Journal of Clinical and Translational hepatology 2024年第7期12卷 659-666页

作者： Zi-Xuan qiu Lin-xiang Huang Xiao-Xiao Wang Zi-Long Wang Xiao-he Li Bo Feng Peking University People’s Hospital Peking University Hepatology InstituteBeijing Key Laboratory of Hepatitis C and Immunotherapy for Liver DiseasesBeijing International Cooperation Base for Science and Technology on NAFLD DiagnosisBeijingChina

The incidence of autoimmune liver diseases(ALDs)and research on their pathogenesis are increasing ***,except for autoimmune hepatitis,which responds well to immunosuppression,primary biliary cholangitis and primary sclerosing cholangitis are insensitive to immunosuppressive *** the known effects of the environment,genetics,and immunity on ALDs,the heterogeneity of target cells provides new insights into their *** review started by exploring the heterogeneity in the development,structures,and functions of hepatocytes and epithelial cells of the small and large bile *** example,cytokeratin(CK)8 and CK18 are primarily expressed in hepatocytes,while CK7 and CK19 are primarily expressed in intrahepatic ***,emerging technologies of single-cell RNA sequencing and spatial transcriptomic are being applied to study *** review offered a new perspective on understanding the pathogenic mechanisms and potential treatment strategies for ALDs.

关键词： Autoimmune hepatitis Primary biliary cholangitis Primary sclerosing cholangitis Disease heterogeneity Single-cell RNA sequencing Pathogenesis

发酵法提取梨渣、姜渣和豆渣膳食纤维的分离纯化及表征

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食品安全质量检测学报 2024年第2期15卷 296-306页

作者：储兆琳邱鹤翔李振宏穆冬冬李兴江洪泂吴学凤合肥工业大学食品与生物工程学院农产品现代加工安徽省重点实验室安徽省发酵食品工程研究中心合肥230601 安徽梨多宝生物科技有限公司宿州235300 中国科学技术大学生命科学学院合肥230027

目的采用发酵法提取果蔬渣膳食纤维,并对分离纯化后的膳食纤维进行结构表征。方法利用红曲霉发酵梨渣、姜渣和豆渣制备可溶性膳食纤维,采用离子交换层析柱和凝胶层析柱对制备的可溶性膳食纤维进行分离纯化,通过扫描电镜、气相色谱-质谱... 详细信息

目的采用发酵法提取果蔬渣膳食纤维,并对分离纯化后的膳食纤维进行结构表征。方法利用红曲霉发酵梨渣、姜渣和豆渣制备可溶性膳食纤维,采用离子交换层析柱和凝胶层析柱对制备的可溶性膳食纤维进行分离纯化,通过扫描电镜、气相色谱-质谱法和红外光谱等方法进行微观结构、单糖组成和官能团分析,并测定其热特性和抗氧化活性。结果红曲霉发酵后梨渣可溶性膳食纤维、姜渣可溶性膳食纤维和豆渣可溶性膳食纤维产量分别为6.28%、4.50%和7.69%;这些纤维的结构呈疏松多孔状态;主要的组成成分包括鼠李糖、阿拉伯糖、木糖、葡萄糖醛酸、葡萄糖和半乳糖;所有纤维样品在红外光谱图中4000~500 cm‒1范围内均具有多糖的特征吸收峰。此外,这3种果蔬渣可溶性膳食纤维表现出一定的热稳定性和抗氧化能力,其中姜渣可溶性膳食纤维的2,2’-联氮-二(3-乙基-苯并噻唑啉-6-磺酸)二铵盐[2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)ammonium salt,ABTS]阳离子自由基清除率和1,1-二苯基-2-三硝基苯肼(1,1-diphenyl-2-picrylhydrazyl,DPPH)自由基清除率分别达到了86.65%和51.61%。结论红曲霉发酵制备的果蔬渣可溶性膳食纤维的各方面理化性质较为优异,在功能性食品领域具有应用潜力。

关键词：可溶性膳食纤维红曲霉结构抗氧化活性

The innovative safe herbicide dienediamine saves paraquat

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Molecular Plant 2024年第1期17卷 11-12页

作者： Jin-qiu Xia Ping Xu Cheng-Bin xiang Division of Life Sciences and Medicine Division of Molecular&Cell BiophysicsHefei National Science Center for Physical Sciences at the MicroscaleMOE Key Laboratory for Membraneless Organelles and Cellular DynamicsUniversity of Science and Technology of ChinaThe Innovation Academy of Seed DesignChinese Academy of SciencesHefeiAnhui Province 230027China Shanghai Key Laboratory of Plant Functional Genomics and Resources Shanghai Chenshan Botanical GardenShanghai Chenshan Plant Science Research CenterCAS Center for Excellence in Molecular Plant SciencesShanghai 201602China

Throughout the history of agriculture,the challenge of weed management has endured,necessitating significant investments to facilitate ideal crop growth and maximize *** for weed control mainly involve manual and chem... 详细信息

关键词： approach. manual chemical

Numerical investigation on compressible flow around a cylinder in proximity to the heated wall

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Journal of Hydrodynamics 2024年第3期36卷 519-533页

作者： Yu-lu Liu Jun-wang Qu Yi-zhou Tao Yong-guang Lyu xiang qiu Shanghai Institute of Technology School of ScienceShanghai201418China Shanghai Key Laboratory of Mechanics in Energy Engineering Shanghai Institute of Applied Mathematics and MechanicsSchool of Mechanics and Engineering ScienceShanghai UniversityShanghai200072China

In this study,direct numerical simulations were conducted to investigate the compressible flow around a circular cylinder near a heated wall at a Reynolds number(Re)of 500 and a Mach number(Ma)of *** heating ratio T^(*)ranging from 1.0 to 1.6 represents the different situations of a heated wall,whereas the gap ratio ranges from 0.3 to *** study analyzed the impact of heating effect and wall proximity on flow characteristics and aerodynamic *** results indicated that the stability of the flow was enhanced as the gap ratio decreased or the heating ratio *** the calculation of enstrophy,it was found that the strength of shedding vortices weakens with a decrease in gap ratio or an increase in heating ***,the mean drag coefficient decreases as the heating ratio increases or the gap ratio *** contrast,the mean lift coefficient initially decreases and then increases as the gap ratio ***,the drag reduction mechanism was analyzed by examining the pressure distribution on the surface of the cylinder.

关键词： Compressible flow wall proximity heating effect stability enstrophy

Effectivity and safety of trifocal intraocular lenses and capsular tension rings implantation for cataract patients with axial high myopia

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 499-508页

作者： Shan Hua qiu-Xia Xie Hu Wang Jing-xiang Zhong Dongguan Aier Eye Hospital Jinan UniversityDongguan 523106Guangdong ProvinceChina Department of Ophthalmology the First Affiliated Hospital of Jinan UniversityGuangzhou 510630Guangdong ProvinceChina Department of Ophthalmology the Sixth Affiliated Hospital of Jinan UniversityDongguan 523576Guangdong ProvinceChina

●AIM:To assess effectivity and safety of trifocal intraocular lenses(IOLs)and capsular tension rings in treating cataract patients with axial high myopia.●METHODS:A prospective nonrandomized controlled clinical trial was *** 98 eyes(74 patients)who underwent femtosecond laser-assisted cataract surgery(FLACS)with trifocal IOLs were enrolled in the study and followed up for 2y after surgery:46 eyes(33 patients)with capsular tension ring implantation in the long axial lengths(AL)group(26he normal AL group(22he subjective and objective visual quality,and postoperative complications were assessed.●RESULTS:Uncorrected distance visual acuity at 5 m and uncorrected intermediate visual acuity at 60 and 80 cm in the long AL group were significantly worse than those in the normal AL group at 3mo postoperatively(Phe differences in reading speed,spectacle independence and potential visual complaints between the two groups were not statistically significant(P>0.05).The dysfunctional lens index and total modulation transfer function(MTF)average height were similar between the two *** postoperative internal coma aberrations in the axial high myopia eyes were significantly higher than that in the normal AL group(Phe total satisfaction score in the long AL group(91.32±2.76)was slightly higher than that in the normal AL group(90.36±3.47),but there was no difference(P=0.136).A statistically negative correlation was found between corrected distance visual acuity(CDVA)and dysfunctional lens index(r=-0.382,P=0.009),and between CDVA and the total MTF average height(r=-0.374,P=0.01).But there was no significant correlation between CDVA and total satisfaction score(r=0.059,P=0.696).Postoperative complications mainly presented as posterior capsular opacity(PCO),retinal detachment and cystoid macular *** was no difference in the incidenc

关键词： trifocal intraocular lenses capsular tension ring axial high myopia cataract visual quality

Effect of programmed comprehensive nursing on delirium incidence in intensive care unit children following severe cardiac surgery

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World Journal of Psychiatry 2024年第9期14卷 1301-1307页

作者： qiu-Yue Wang xiang Wang Ming-Xiong Li Department of Cardiothoracic Surgery Children’s Hospital of Nanjing Medical UniversityNanjing 210000Jiangsu ProvinceChina

BACKGROUND Programmed comprehensive nursing was adopted for intensive care unit(ICU)children following severe cardiac surgery to improve respiratory function and delirium *** To explore how programmed comprehensive nursing impacts respiratory func-tion and delirium incidence in ICU children post cardiac *** Between January 2022 and January 2024,180 pediatric patients from the Chil-dren’s Hospital of Nanjing were admitted to the ICU after cardiac surgery and randomly *** control group comprised 90 patients and received routine nursing *** observation group comprised 90 patients and received program-med comprehensive *** groups received continuous nursing care until *** respiratory function,incidence of delirium,and clinical outcomes were *** memory state and sleep quality of both groups were *** The incidence of delirium was 5.56%in the observation group when admitted to ICU,which was lower than that in the control group(20.00%;Phe observation group demonstrated higher peak expiratory flow rate,respiratory frequency,deep breathing volume,and tidal volume in the ICU compared with the control ***,the observation group showed higher sleep depth,sleep latency,night awakening,return to sleep,and sleep quality com-pared with the control group(Phensive nursing in ICU patients following severe cardiac surgery can reduce the impact on respiratory function,improve sleep quality,and alleviate postoperative delirium,showing significant promise for clinical application.

关键词： Programmed comprehensive nursing Intensive care unit Cardiac surgery Respiratory function Delirium

MnS–MnO heterogeneous nanocube@N,S-doped carbon as a highly efficient bifunctional water splitting electrocatalyst

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Rare Metals 2024年第5期43卷 1977-1988页

作者： Xue-Qian Wang xiang-Ying Ma Wang-Zhi Wu Hui-Bing he Nan-Nan Wang Ren-Ji Zheng Shao-Jian Ma Yan-qiu Zhu Pei-Kang Shen Jin-Liang Zhu School of Resources Environment and MaterialsState Key Laboratory of Featured Metal Materials and Life-Cycle Safety for Composite StructuresCollege of Chemistry and Chemical EngineeringGuangxi UniversityNanning 530004China School of Chemistry and Chemical Engineering Guangxi MinzuUniversity Nanning 530006 China School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China

A stable,efficient,and economical bifunctional electrolytic catalyst would be incredibly beneficial for the development of hydrogen production by electrocatalytic water *** this study,we synthesized a novel MnS–MnO heterogeneous nanocube@N,S-doped carbon(MnS–MnO@NSC).MnS–MnO nanocubes possess rich heterogeneous interfaces and plentiful catalytic active sites to promote electrochemical reactions,while the N,S-doped carbon shell possesses excellent conductivity and catalytic properties and protects the ***–MnO@NSC exhibited excellent electrochemical properties as an effective bifunctional electrocatalyst for the hydrogen evolution reaction(heR)and oxygen evolution reaction(OER)in KOH *** the heR,the overpotential was as low as 124 mV at a current density of 10 mA·cm^(-2)while in the OER,it was only 340 mV at 100 mA·cm^(-2)under the same *** addition,a MnS–MnO@NSC||MnS–MnO@NSC electrolyzer exhibited almost comparable activity and higher steadiness than those exhibited by the state-of-the-art Pt/C||RuO_(2)/C system for full water splitting in KOH solution.

关键词： Manganese sulfide Manganese oxide Doped carbon heterogeneous nanocube Water splitting

Insider threat detection approach for tobacco industry based on heterogeneous graph embedding

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High Technology Letters 2024年第2期30卷 199-210页

作者：季琦 LI Wei PAN Bailin XUE Hongkai qiu xiang Hangzhou Cigarette Factory China Tobacco Zhejiang Industrial Co.Ltd.Hangzhou 310024P.R.China Information Center China Tobacco Zhejiang Industrial Co.Ltd.Hangzhou 310024P.R.China College of Information Engineering Zhejiang University of TechnologyHangzhou 310014P.R.China

In the tobacco industry,insider employee attack is a thorny problem that is difficult to *** solve this issue,this paper proposes an insider threat detection method based on heterogeneous graph ***,the interrelationships between logs are fully considered,and log entries are converted into heterogeneous graphs based on these ***,the heterogeneous graph embedding is adopted and each log entry is represented as a low-dimensional feature ***,normal logs and malicious logs are classified into different clusters by clustering algorithm to identify malicious ***,the effectiveness and superiority of the method is verified through experiments on the CERT *** experimental results show that this method has better performance compared to some baseline methods.

关键词： insider threat detection advanced persistent threats graph construction heterogeneous graph embedding

Aflatoxin B1 decreased flesh flavor and inhibited muscle development in grass carp(Ctenopharyngodon idella)

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Animal Nutrition 2024年第3期18卷 27-38页

作者： xiang Ning he Zhen Zhen Zeng Wei Dan Jiang Pei Wu Yang Liu Sheng Yao Kuang Ling Tang Shu Wei Li Lin Feng Xiao qiu Zhou Animal Nutrition Institute Sichuan Agricultural UniversityChengdu 611130China Fish Nutrition and Safety Production University Key Laboratory of Sichuan Province Sichuan Agricultural UniversityChengdu 611130China Key Laboratory for Animal Disease-Resistance Nutrition Ministry of EducationMinistry of Agriculture and Rural AffairsKey Laboratory of Sichuan ProvinceChengdu 611130China Animal Nutrition Institute Sichuan Academy of Animal ScienceChengdu 610066China

In nature,aflatoxins,especially aflatoxin B1(AFB1),are the common mycotoxins,which cause serious health problems for humans and *** paper aimed to study the effects of AFB1 on flesh flavor and muscle development of grass carp(Ctenopharyngodon idella)and its *** were 1440 individual fish in total,with 6 treatments and each treatment replicated 3 *** 6 treatments were fed a control diet with different doses of AFB1(0.04,29.48,58.66,85.94,110.43 and 146.92μg/kg diet)for 60 ***1 increased myofiber diameter,as well as decreased myofiber density of grass carp muscle(Phe contents of free amino acid decreased gradually(Phe muscle of grass *** levels of reactive oxygen species,malonaldehyde and protein carbonyl(PC)were increased(Phe dietary AFB1 *** levels of antioxidant enzyme(glutathione peroxidase,glutathione,glutathione reductase,total antioxidant capacity,anti-superoxide anion,and anti-hydroxyl radical)were decreased(Phe dietary AFB1 *** addition,dietary AFB1 decreased the content of collagen,and downregulated the mRNA and protein levels of transforming growth factor-β(TGF-β)/Smads signaling pathway in grass carp muscle(Phe mRNA and protein levels of myogenic regulatory factors were downregulated in grass carp muscle(Phermore,the activities of matrix metalloproteinase-2(MMP-2)and matrix metalloproteinase-9(MMP-9)were increased(Phe protein levels of phosphorylate-38 mitogen-activated protein kinase(p-p38MAPK),phosphorylate-c-Jun N-terminal kinase,urokinase-type plasminogen activator(uPA),MMP-2 and MMP-9 were upregulated(Phe dietary AFB1 increased in the muscle of grass *** on the results of this study,we can draw the following conclusion:dietary AFB1 might damage flesh flavor and inhibit the muscle development through MAPK/uPA/MMP/extrac

关键词： Aflatoxin B1 Flesh flavor Muscle development Grass carp