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Particuology 2021年第5期19卷 206-213页

作者： Xiaofeng Shi Junmao Hong Chao Wang Sifang Kong Junhua Li Duo Pan Jing Lin qinglong jiang Zhanhu Guo School of Environment and Safety Engineering Institute of Advanced Energy Materials and SystemsNorth University of ChinaTaiyuan 030051China School of Traffic&Environment Shenzhen Institute of Information TechnologyShenzhen 518172China School of Chemistry and Chemical Engineering Guangzhou UniversityGuangzhou 510006China Key Laboratory of Materials Processing and Mold(Zhengzhou University) Ministry of EducationNational Engineering Research Center for Advanced Polymer Processing TechnologyZhengzhou UniversityZhengzhou 450001China Integrated Composites Laboratory(ICL) Department of Chemical and Bimolecular EngineeringUniversity of TennesseeKnoxvilleTN 37996USA Department of Chemistry and Physics University of ArkansasPine BluffAR 71601USA

Among various environmental problems,water pollution has drawn more and more *** develop an adsorbent with enhanced selectivity and high capacity for As(V)oxyanion,a novel lignin-based adsorbent was prepared by doping with N and modifying with Mg^(2+),using thiethylenetetramine(TETA)and MgCl_(2) as the source of N and Mg^(2+),respectively.N-doped lignin(NL)shows a high selectivity for As(Ⅴ),which is further enhanced by modifying with Mg^(2+)(MNL).MNL shows an excellent *** adsorption isotherms and kinetics of MNL for As(Ⅴ)follow Langmuir isotherms model and pseudo-second-order kinetics model,*** adsorption of MNL for As(Ⅴ)achieved a maximum adsorption capacity of 687.46 mg g^(−1) and the equilibrium was established within 30 *** study offers a novel idea on the recycle of the waste of paper industry and provides a new technology for As(Ⅴ)adsorption from wastewater.

关键词： Adsorbents Doping Heavy metals Adsorption Selectivity

Susceptibility Test of Culter mongolicus to Several Kinds of Common Drugs

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Agricultural Biotechnology 2015年第1期4卷 42-43页

作者： qinglong jiang Baohua YAN Nanchang Academy of Agricultural Science

[ Objective ] This study aimed to provide references for reasonable drug administration in Culter mongolicus and promote the development of its breeding industry. [Method] C. mongolicus was administrated with cypermethrin, mebendazole, trichlorfon, cupric sulfate, trichloroisocyanuric acid, povidone iodine and phoxim, respectively, to analyze its susceptibility to different drugs. [ Result] C. mongolicus was very sensitive to cypermethrin; the median tolerance limit （TLM） at 3,8 h was 0. 072mg/L, minimum lethal concentration was 0. 063 - 0. 069 mg,/L, safe concentration was 0. 021 6 mg/L. C. mongolicus was insensitive to mebendazole, trichlorfon, cupric sulfate, trichloroisocyanuric acid and povidone iodine. According to safe concentration of various drugs, C. mongolicus exhibited higher susceptibility to cypermethrin than to phoxim. [ Conclusion] This study laid a solid foundation for better protection and development of C. mongolicus resources.

关键词： Culter mongolicus Susceptibility Safe concentration

Pesticide Susceptibility of Silurus asotus Linnaeus from Poyang Lake

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Agricultural Biotechnology 2016年第2期5卷 51-52页

作者： qinglong jiang Yi YAO Yulan WANG Nanchang Academy of Agricultural Science Nanchang 330008 China

In this study, the susceptibility of S. asotus Linnaeus from Poyang Lake to several common pesticides was investigated. The results showed that S. aso- tus Linnaeus from Poyang Lake was susceptible to cypermethrin, and the 48 h minimum lethal concentration ranged between 0.063 - 0.069 mg/L. This study pro- vided reference for scientific medication and development of commercial production of S. asotus Linnaeus in Poyang Lake.

关键词： Silurus asotus Linnaeus Pesticide Susceptibility

The remarkable effect of amino hydrogen on membrane permeability and organelle staining of 1,8-naphthalimide dyes

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Chinese Chemical Letters 2024年第2期35卷 347-351页

作者： Zhifeng Li qinglong Qiao Ning Xu Kai An Wenchao jiang Yi Tao Pengjun Bao Yinchan Zhang Zhaochao Xu School of Chemistry Dalian University of TechnologyDalian 116024China CAS Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China University of Chinese Academy of Sciences Beijing 100049China

Membrane permeability and intracellular diffusion of fluorescent probes determine staining selectivity of intracellular ***,the relationship between the molecular structure of fluorescent probes and their membrane permeability and intracellular distribution is poorly *** this paper,we reported a series of 1,8-naphthalimide dyes and carried out cell imaging experiments,and found that the presence of amino hydrogen in these dyes played a crucial role in their cell membrane permeability and intracellular *** secondary amino group containing compounds 1-4 show excellent membrane permeability and strong fluorescence in living *** the tertiary amine containing dyes 5 and 6 can hardly permeate the cell membrane though they show extremely similar structure with compounds *** 1 can selectively image lipid droplets by selecting the wavelength of excitation *** the specificity for lysosomes,2 and 4 have been used in long-term time-lapses imaging of lysosomal dynamics and tracking the process of lysosome-lysosome interaction,fusion and *** effect of hydrogen-containing amino substituent on the cell membrane permeability of fluorescent molecules is promising for the development of better biocompatible probes.

关键词： Amino hydrogen 1,8-Naphthalimide Cell permeability Lipid droplet Lysosome

Application Effect of Micropore Aeration Technique in Rearing Process of Summer Fingerlings of Silurus asotus from Poyang Lake

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Agricultural Biotechnology 2016年第5期5卷 30-32页

作者： Yi YAO Chunxian XIONG Liangqing XU qinglong jiang Lan LAN Lougen ZENG Nanchang Academy of Agricultural Science Nanchang 330006 China

Application effect of micropore aeration technique in rearing process of summer fingerlings of Silurus asotus from Poyang lake was studied. This study provides an efficient safe aeration solution for large-scale finge... 详细信息

关键词： Silurus asotus Aeration technique Solution

Graph based recurrent network for context specific synthetic lethality prediction

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Science China Life Sciences 2024年

作者： Yuyang jiang Jing Wang Yixin Zhang ZhiWei Cao qinglong Zhang Jinsong Su Song He Xiaochen Bo Academy of Medical Engineering and Translational Medicine Tianjin University Department of Bioinformatics Institute of Health Service and Transfusion MedicineBeijing School of Medicine Tsinghua University School of Informatics Xiamen University

The concept of synthetic lethality (SL) has been successfully used for targeted therapies. To further explore SL for cancer therapy, identifying more SL interactions with therapeutic potential are essential. Recently, graph neural network-based deep learning methods have been proposed for SL prediction, which reduce the SL search space of wet-lab based methods. However, these methods ignore that most SL interactions depend strongly on genetic context, which limits the application of the predicted results. In this study, we proposed a graph recurrent network-based model for specific context-dependent SL prediction (SLGRN). In particular, we introduced a Graph Recurrent Network-based encoder to acquire a context-specific, low-dimensional feature representation for each node, facilitating the prediction of novel SL. SLGRN leveraged gate recurrent unit (GRU) and it incorporated a context-dependent-level state to effectively integrate information from all nodes. As a result, SLGRN outperforms the state-of-the-arts models for SL prediction. We subsequently validate novel SL interactions under different contexts based on combination therapy or patient survival analysis. Through in vitro experiments and retrospective clinical analysis, we emphasize the potential clinical significance of this context-specific SL prediction model.

关键词：

Construct Higher Vocational Practice Teaching System Based on "Teaching Factory" Concept

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Construct Higher Vocational Practice Teaching System Based o...

2012管理创新、智能科技与经济发展研讨会

作者： Li GE,Jiaji jiang,qinglong SHAO,Mingjun LIU Shenzhen Institute of Information Technology,Shenzhen,Guangdong,518029

In this paper with research subject of "Mold Design and Manufacturing" major,the way to construct a practice teaching system in conformance with Chinese higher vocational education characteristic and create a practice teaching platform in accordance with corporate structure in a real production environment is developed by learning from Singapore "Teaching Factory" concept;both innovation of 4-Stage progressive "Work and Study Integration" talent development mode and implementation of corporate operation mode to effectively improve students' high-end skill level and vocational accomplishment are introduced in order to provide new idea and new method of higher vocational education "Work and Study" reform by strengthening self-employment and innovation type education.

关键词： Teaching Factory Corporate Operation 4-Stage Progressive Work and Study Integration

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黄土高原沟壑区粮食生产的资源环境成本

农业工程学报 2011年第6期27卷 269-277页

作者：张应龙谢永生文曼江青龙李晓西北农林科技大学资源环境学院杨凌712100 中国科学院水利部水土保持研究所杨凌712100

针对粮食生产过程中的资源消耗和环境降级问题,以黄土高原沟壑区的陕西省长武县为研究对象,运用环境经济学估算方法,对粮食生产的资源环境成本进行了研究。结果表明:2008年该区粮食生产资源环境损失总价值相当于当年农业总产值的19.05%... 详细信息

针对粮食生产过程中的资源消耗和环境降级问题,以黄土高原沟壑区的陕西省长武县为研究对象,运用环境经济学估算方法,对粮食生产的资源环境成本进行了研究。结果表明:2008年该区粮食生产资源环境损失总价值相当于当年农业总产值的19.05%;小麦和玉米的资源环境成本分别达到2.02和1.19元/kg,总成本分别为4.08和2.23元/kg,而出售价格仅1.72和1.28元/kg,高成本低效益状况对区域粮食安全及生态经济持续发展产生不利影响;对粮食总成本中的各要素进行因子分析得出,资源环境成本和化肥费用是其主要因素。在现有生产条件下加大农业科技投入,提高生产资料利用效率,发展现代生态农业,是降低粮食成本维持区域持续发展的重要举措。

关键词：成本估算生产粮食资源环境黄土高原沟壑区

含氯消毒液对耐甲氧西林阳性和阴性金黄色葡萄球菌杀灭效果观察

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中国药师 2006年第7期9卷 631-632页

作者：段韵姜青龙江西省人民医院药剂科南昌330006 江西省临床检验中心

目的:耐甲氧西林金黄色葡萄球菌是导致院内感染的常见菌株,了解其对常用消毒液的抵抗力。方法:采用悬液定量试验对含氯消毒液(921消毒剂)杀灭耐甲氧西林阳性和阴性金黄色葡萄球菌的效果进行比较。结果:1:100稀释的921消毒液作用3 min对... 详细信息

目的:耐甲氧西林金黄色葡萄球菌是导致院内感染的常见菌株,了解其对常用消毒液的抵抗力。方法:采用悬液定量试验对含氯消毒液(921消毒剂)杀灭耐甲氧西林阳性和阴性金黄色葡萄球菌的效果进行比较。结果:1:100稀释的921消毒液作用3 min对耐甲氧西林阴性金黄色葡萄球菌杀灭率达100％;用同样含量和作用时间,对耐甲氧西林阳性金黄色葡萄球菌杀灭率依次分别为82．75％;但将作用时间延长至5 min,上述剂量的消毒液对两种菌杀灭率均可达到100％,对表面擦拭3遍消毒亦得到同样的效果。结论:耐甲氧西林阳性金黄色葡萄球菌对含氯消毒液抵抗力比耐甲氧西林阴性者强。

关键词：耐甲氧西林金黄色葡萄球菌含氯消毒液抵抗力

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甘肃省河西地区板蓝根当年抽薹主要因子分析

分子植物育种 2016年第5期14卷 1230-1235页

作者：袁克录姜青龙李继强周晖凯李伟张掖市农业科学研究院张掖734000

本研究从栽培学角度研究了甘肃河西走廊地区板蓝根由于当年抽薹,造成产量降低、药用根严重木质化、药用价值降低等问题。为此安排品种与栽培试验6项,寻找该地区板蓝根当年抽薹的原因及解决办法,同时确定适宜品种、播期、密度、施肥及栽... 详细信息

本研究从栽培学角度研究了甘肃河西走廊地区板蓝根由于当年抽薹,造成产量降低、药用根严重木质化、药用价值降低等问题。为此安排品种与栽培试验6项,寻找该地区板蓝根当年抽薹的原因及解决办法,同时确定适宜品种、播期、密度、施肥及栽培方式。结果表明:当年播种后抽薹的板蓝根母根所收获的种子种植后抽薹率达35%,是造成板蓝根当年播种当年抽薹的主要因子,同时证明当年抽薹的种子是受遗传作用,种子在收获时已经部分完成春化;过早播种是造成板蓝根提前春化当年抽薹的次要因子。

关键词：板蓝根当年抽薹因子分析