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Rare Metals 2021年第8期40卷 2118-2126页

作者： Ming Wang hao-qing li Hong Guo liu Feng Shu-Yu liu Xiao-Ying Fang Institute for Advanced Manufacturing Shandong University of TechnologyZibo255000China Center of Testing and Analysis Shandong University of TechnologyZibo255000China School of Mechanical Engineering Shandong University of TechnologyZibo255000China

It is important to understand the correlation between grain morphology and intervariant boundaries of theαphase after heat treatment belowβtransus of the electron beam melted(EBMed)Ti-6 Al-4 V *** electron microscopy(SEM)and electron backscatter diffraction(EBSD)analysis have shown about 99%αphase and 1%βphase in the heat-treated samples when the temperature rises to 950℃.Four distinct types ofαgrain morphology have been found:allotromorphousα,relatively coarseαplate,large precipitationαand granularα.A single peak of the intervariant boundary with the misorientation of 60°/[1120]associated with Burgers orientation relationship(OR)was found in the allotromorphousα*** intervariant boundaries mixed with a fraction of general high-angle grain boundary(GHABs,not Burgers OR)were present in the relatively coarseαplate *** only low-angle grain boundaries(LABs)with the misorientation of<5°were found in the large precipitationαgrains.βphase tends to distribute around the boundaries of relatively coarseα*** suggests that different formation mechanisms are involved in the distinct types ofαgrain morphology.

关键词： Intervariant boundaries Electron beam melting Ti-6Al-4V alloy Heat treatment

Oxygen vacancy control of electrical,optical,and magnetic properties of Fe_(0.05)Ti_(0.95)O_(2) epitaxial films

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Chinese Physics B 2021年第11期30卷 575-579页

作者： qing-Tao Xia Zhao-Hui li Le-qing Zhang Feng-ling Zhang Xiang-Kun li Heng-Jun liu Fang-Chao Gu Tao Zhang Qiang li qing-hao li College of Physics University-Industry Joint Center for Ocean Observation and Broadband CommunicationQingdao UniversityQingdao 266071China

High-quality Fe-doped TiO_(2) films are epitaxially grown on MgF_(2) substrates by pulsed laser *** x-ray diffraction and Raman spectra prove that they are of pure rutile ***-resolution transmission electron microscopy(TEM)further demonstrates that the epitaxial relationship between rutile-phased TiO_(2) and MgF_(2) substrates is 110 TiO_(2)||110 MgF_(2).The room temperature ferromagnetism is detected by alternative gradient *** increasing the ambient oxygen pressure,magnetization shows that it decreases monotonically while absorption edge shows a red *** transport property measurement demonstrates a strong correlation between magnetization and carrier *** influence of ambient oxygen pressure on magnetization can be well explained by a modified bound magnetization polarization model.

关键词： ferromagnetic materials semiconductors epitaxial films rutile TiO_(2)

Observation and mitigation of image distortion in high-energy electron radiography

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Nuclear Science and Techniques 2023年第6期34卷 69-77页

作者： hao-qing li liang Sheng Chang-qing Zhang Ying-Chao Du Zheng Zhou Xiu-Feng Weng Jia-hao Xiao Hong-Qiao Yin Bin Sun Kun Wei Yang li Bao-Jun Duan Yong-Tang liu Yan-Hong Zhang Mei Zhang Yan Song Xiao-Dong Zhang Jun liu Zhu-Ming Fu qing Xu Xue Du Jian-Peng Gao Xin-Yi Wang Xin-Jian Tan Dong-Wei Hei Department of Engineering Physics Tsinghua UniversityBeijing100084China State Key Laboratory of Intense Pulsed Radiation Simulation and Effect Northwest Institute of Nuclear TechnologyXi’an710024China Institute of Applied Electronics China Academy of Engineering PhysicsMianyang621900China Institute of Intelligent Machines Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei230031China Zhongke Hefei Institutes of Collaborative Research and Innovation for Intelligent Agriculture Hefei231131China

Image distortion caused by the angular misalignment of quadrupole magnets in high-energy electron radiography has been studied *** propose that the distortion originates from the coupling of the electron motions in the transverse directions,based on a theoretical analysis and the transfer-matrix *** relative angular rotation between the second and third magnetic quadrupoles was identified as the main contributor to image *** was verified by both a beam-dynamics simulation and *** strategies to mitigate this image distortion are also explored,including magnets online tuning,higher beam energy and larger magnification *** study provides criteria for designing experiments and paves the way for achieving higher image precision.

关键词： Misalignment Angular rotation Russian quadruplet Transfer matrix

Blocking effects of siRNA on VEGF expression in human colorectal cancer cells

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World Journal of Gastroenterology 2010年第9期16卷 1086-1092页

作者： Yu Yin,li-Yu Cao,Wen-qing Wu,hao li,Yan Jiang,Hong-Fu Zhang,Department of Pathology,Anhui Medical University,Hefei 230032,Anhui Province,China Wen-qing Wu,Department of Pathology,Anhui Provincial Hospital,Hefei 230001,Anhui Province,China Department of Pathology Anhui Medical University Hefei 230032 Anhui Province China. caoliyu@***

AIM:To investigate the expression of vascular endothelial cell growth factor (VEGF) and its receptors Fmslike tyrosine kinase 1 (FLT-1) and fetal liver kinase 1 (FLK-1) in colorectal carcinoma (CRC),and the blocking effects of small interfering RNAs (siRNAs) on VEGF expression in human colorectal cancer HCT116 ***:Immunohistochemical staining for VEGF,FLT-1 and FLK-1 proteins was performed in 82 cases of CRC and 14 normal colorectal mucosae.A siRNA targeting VEGF was synthesized and transfected into HCT116 cells using lipofectamine *** staining and Western blotting analyses were performed to detect the expression of VEGF *** suppressive effect of the siRNA on cell proliferation was detected using the 3-(4,5-dimethylthiazol-2-yl)2,5-diphenyltertrazolium bromide (MTT) *** apoptosis was detected using flow cytometry (FCM).RESULTS:The expression of VEGF,FLT-1 and FLK-1 in tumor tissues was significantly higher than that in normal tissues (P=0.008,P=0.000,P=0.000).The expression of VEGF was positively correlated with both lymph node metastasis and clinical stage (P=0.009 and P=0.025,respectively).Immunocytochemistry showed that the expression of VEGF was weakly positive and Western blotting indicated a significant reduction in VEGF-siRNA cell protein ***-siRNA cell growth inhibition was assessed by the MTT assay,and the tumor cell proliferation rate was significantly different at 24,48,and 72 h after *** results showed that the VEGF-siRNA group had an apparent aneuploid ***:VEGF,FLT-1 and FLK-1 are associated with colorectal *** silencing of the VEGF gene suppresses proliferation,and induces apoptosis in HCT116 *** results suggest that VEGF may be a new gene therapy target for colorectal cancer.

关键词： Colorectal carcinoma Vascular endothelial cell growth factor Fms-like tyrosine kinase 1 Fetal liver kinase 1 Small interfering RNA

Theoretical characterization of the adsorption configuration of pyrrole on Si(100)surface by x-ray spectroscopy

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Chinese Physics B 2024年第2期33卷 430-435页

作者：李好情明静姜志昂李海波马勇宋秀能 School of Physics and Electronics Shandong Normal UniversityJinan 250358China

The possible configurations of pyrrole absorbed on a Si(100)surface have been investigated by x-ray photoelectron spectroscopy(XPS)and near-edge x-ray absorption fine structure(NEXAFS)*** C-1s XPS and NEXAFS spectra of these adsorption configurations have been calculated by using the density functional theory(DFT)method and fullcore hole(FCH)approximation to investigate the relationship between the adsorption configurations and the *** result shows that the XPS and NEXAFS spectra are structurally dependent on the configurations of pyrrole absorbed on the Si(100)*** with the XPS,the NEXAFS spectra are relatively sensitive to the adsorption configurations and can accurately identify *** NEXAFS decomposition spectra produced by non-equivalent carbon atoms have also been calculated and show that the spectral features vary with the diverse types of carbon atoms and their structural environments.

关键词： pyrrole silicon surface x-ray photoelectron spectroscopy(XPS) near-edge x-ray absorption fine structure(NEXAFS)

Management of intra-articular fracture of the fingers via mini external fixator combined with limited internal fixation

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Chinese Medical Journal 2009年第21期122卷 2616-2619页

作者： li Wen-jun TIAN Wen TIAN Guang-lei CHEN Shan-lin ZHANG Chang-qing XUE Yun-hao li Zhong-zhe ZHU Yin Department of Hand Surgery Beijing Jishuitan Hospital Beijing 100035 China

Background Intra-articular fractures of the fingers are common problems to emergency physicians and hand surgeons Inappropriate management of these injuries may result in chronic pain, stiffness, deformity, or post traumatic arthritis. Ideal treatment necessitates the restoration of a stable and congruent joint that will allow early mobilization. The purpose of this study was to investigate the results of intra-articular fracture of the fingers by mini external fixator combined with limited internal fixation. Methods From May 2005 to May 2007, a total of 26 patients with intra-articular fracture of the fingers were treated by mini external fixator combined with limited internal fixation. Of the 26 cases, 11 involved in metacarpophalangeal joint, and 15 interphalangeal joint in proximal interphalangeal. Kirschner wire, mini wire and absorbable suture were used for limited internal fixation. All patients were followed up and patients were accomplished with total active motion （TAM） of fingers. Results All patients were reviewed by an independent observer. The mean follow up was 13 months （range 9 to 24 months）. Subjective, objective and radiographic results were evaluated. X-ray films revealed fracture union and the average radiographic union time was 7 weeks with a range of 5-12 weeks and the phalange shortening or rotation in 2 cases, joint incongruity （less than 1 mm） and joint space narrowing in 3 cases respectively. Phalangeal shortening or rotation was observed in 2 cases and joint incongruity or joint space narrowing was observed in 3 cases. An artificial implant was performed on one case for traumatic arthritis 1.5 years after surgery. Based on TAM the overall good-excellent rate of joint motion function was 80.8%. Conclusion Mini external fixator combined with limited internal fixation is a reliable and effective method for treatment of intra-articular fracture of the fingers.

关键词： external fixator intra-articular fracture internal fixation finger

Effect of pyrite content on chalcopyrite flotation under different regrinding conditions

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 49-57页

作者： Zejun Wang qing Shi Guofan Zhang Yuxuan Zhu Binbin li School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China Key Laboratory of Hunan Province for Clean and Efficient Utilization of Strategic Calcium-containing Mineral Resources Central South UniversityChangsha 410083China

This study aimed to investigate the effect of varying pyrite(Py)content on copper(Cu)in the presence of different regrinding conditions,which were altered using different types of grinding media:iron,ceramic balls,and their mixture,followed by flotation in the cleaner *** flotation performance of rough Cu concentrate can be improved by changing the regrinding conditions based on the Py *** electron microscopy,X-ray spectrometry,ethylenediaminetetraacetic acid disodium salt extraction,and X-ray photoelectron spectroscopy studies illustrated that when the Py content was high,the use of iron media in regrinding promoted the generation of hydrophilic Fe OOH on the surface of Py and improved the Cu *** ceramic medium with a low Py content prevented excessive Fe OOH from covering the surface of chalcopyrite(Cpy).Electrochemical studies further showed that the galvanic corrosion current of Cpy-Py increased with the addition of Py and became stronger with the participation of iron media.

关键词： chalcopyrite regrinding media pyrite galvanic corrosion flotation

Laser‑Induced Highly Stable Conductive Hydrogels for Robust Bioelectronics

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Nano-Micro Letters 2025年第3期17卷 117-120页

作者： Yibo li hao Zhou Huayong Yang Kaichen Xu State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310058People’s Republic of China

Despite the promising progress in conductive hydrogels made with pure conducting polymer,great challenges remain in the interface adhesion and robustness in longterm *** address these challenges,*** Hwan Ko and Taek-Soo Kim’s team introduced a laserinduced phase separation and adhesion method for fabricating conductive hydrogels consisting of pure poly(3,4-ethylenedioxythiophene):polystyrene sulfonate on polymer *** laser-induced phase separation and adhesion treated conducting polymers can be selectively transformed into conductive hydrogels that exhibit wet conductivities of 101.4 S cm^(−1)with a spatial resolution down to 5μ***,they maintain impedance and charge-storage capacity even after 1 h of *** micropatterned electrode arrays demonstrate their potential in long-term in vivo signal recordings,highlighting their promising role in the field of bioelectronics.

关键词： Laser processing Conductive hydrogels Stable interface Bio-interfacing electrodes Bioelectronic application

Ultra‑High Sensitivity Anisotropic Piezoelectric Sensors for Structural Health Monitoring and Robotic Perception

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Nano-Micro Letters 2025年第2期17卷 432-446页

作者： hao Yin Yanting li Zhiying Tian Qichao li Chenhui Jiang Enfu liang Yiping Guo State Key Laboratory of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China Beijing Vacuum Electronics Research Institute Beijing 100015People’s Republic of China Fundamental Science On Vibration Shock and Noise LaboratoryState Key Laboratory of Mechanical System and VibrationSchool of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Monitoring minuscule mechanical signals,both in magnitude and direction,is imperative in many application scenarios,e.g.,structural health monitoring and robotic sensing ***,the piezoelectric sensor struggles to satisfy the requirements for directional recognition due to the limited piezoelectric coefficient matrix,and achieving sensitivity for detecting micrometer-scale deformations is also ***,we develop a vector sensor composed of lead zirconate titanate-electronic grade glass fiber composite filaments with oriented arrangement,capable of detecting minute anisotropic *** as-prepared vector sensor can identify the deformation directions even when subjected to an unprecedented nominal strain of 0.06%,thereby enabling its utility in accurately discerning the 5μm-height wrinkles in thin films and in monitoring human pulse *** ultra-high sensitivity is attributed to the formation of porous ferroelectret and the efficient load transfer efficiency of continuous lead zirconate titanate ***,when integrated with machine learning techniques,the sensor’s capability to recognize multi-signals enables it to differentiate between 10 types of fine textures with 100%*** structural design in piezoelectric devices enables a more comprehensive perception of mechanical stimuli,offering a novel perspective for enhancing recognition accuracy.

关键词： Flexible piezoelectric filaments Anisotropic Ultra-high sensitivity Structural health detection Texture recognition

Activation of adult endogenous neurogenesis by a hyaluronic acid collagen gel containing basic fibroblast growth factor promotes remodeling and functional recovery of the injured cerebral cortex

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Neural Regeneration Research 2025年第10期20卷 2923-2937页

作者： Yan li Peng hao Hongmei Duan Fei hao Wen Zhao Yudan Gao Zhaoyang Yang Kwok-Fai So Xiaoguang li Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina China Rehabilitation Science Institute China Rehabilitation Research CenterBeijing Key Laboratory of Neural Injury and RehabilitationBeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Beijing Key Laboratory for Biomaterials and Neural Regeneration School of Engineering MedicineBeihang UniversityBeijingChina Guangdong-HongKong-Macao Institute of CNS Regeneration Ministry of Education CNS Regeneration Collaborative Joint LaboratoryJinan UniversityGuangzhouGuangdong ProvinceChina Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) GuangzhouGuangdong ProvinceChina Department of Ophthalmology and State Key Laboratory of Brain and Cognitive Sciences The University of Hong KongHong Kong Special Administration RegionChina Center for Brain Science and Brain-Inspired Intelligence Guangdong-HongKong-Macao Greater Bay AreaGuangzhouGuangdong ProvinceChina Co-innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Biomedical Engineering School of Biological Science and Medical EngineeringBeihang UniversityBeijingChina

The presence of endogenous neural stem/progenitor cells in the adult mammalian brain suggests that the central nervous system can be repaired and regenerated after ***,whether it is possible to stimulate neurogenesis and reconstruct cortical layers II to VI in non-neurogenic regions,such as the cortex,remains *** this study,we implanted a hyaluronic acid collagen gel loaded with basic fibroblast growth factor into the motor cortex immediately following traumatic *** findings reveal that this gel effectively stimulated the proliferation and migration of endogenous neural stem/progenitor cells,as well as their differentiation into mature and functionally integrated ***,these new neurons reconstructed the architecture of cortical layers II to VI,integrated into the existing neural circuitry,and ultimately led to improved brain *** findings offer novel insight into potential clinical treatments for traumatic cerebral cortex injuries.

关键词： adult endogenous neurogenesis basic fibroblast growth factor-hyaluronic acid collagen gel cortical remodeling functional recovery migration motor cortex injury neural circuits neural stem cells newborn neurons proliferation