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略论“德都蒙古”名称及其意义

青海民族研究 2016年第1期27卷 123-126页

作者：青格力中国社会科学院北京102488

近年来"德都蒙古"(degedii mongγol)名称在各个领域被广泛使用。早在蒙元时期已经存在类似的名称"stod hor",而称青海地区蒙古人为"德都蒙古"者,益希班觉为第一人。本文根据文献记载考证这一名称的来源,并对其涵义以及现实意义等作了... 详细信息

近年来"德都蒙古"(degedii mongγol)名称在各个领域被广泛使用。早在蒙元时期已经存在类似的名称"stod hor",而称青海地区蒙古人为"德都蒙古"者,益希班觉为第一人。本文根据文献记载考证这一名称的来源,并对其涵义以及现实意义等作了阐释。

关键词：青海蒙古德都蒙古青藏高原益希班觉内陆欧亚

The complex roles of m^(6)A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases

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Neural Regeneration Research 2025年第6期20卷 1582-1598页

作者： Yanxi li Jing Xue Yuejia Ma Ke Ye Xue Zhao Fangliang ge Feifei Zheng Lulu liu Xu Gao Dayong Wang qing Xia Department of Biochemistry and Molecular Biology College of Basic Medical SciencesHarbin Medical UniversityHarbinHeilongjiang ProvinceChina College of Basic Medical Sciences Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Basic Medical Institute Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Key Laboratory of Heilongjiang Province for genetically Modified Animals Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Translational Medicine Research and Cooperation Center of Northern China Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Dongzhimen Hospital Beijing University of Chinese MedicineBeijingChina

N6-methyladenosine(m^(6)A), the most prevalent and conserved RNA modification in eukaryotic cells, profoundly influences virtually all aspects of mRNA metabolism. mRNA plays crucial roles in neural stem cell genesis and neural regeneration, where it is highly concentrated and actively involved in these processes. Changes in m^(6)A modification levels and the expression levels of related enzymatic proteins can lead to neurological dysfunction and contribute to the development of neurological diseases. Furthermore, the proliferation and differentiation of neural stem cells, as well as nerve regeneration, are intimately linked to memory function and neurodegenerative diseases. This paper presents a comprehensive review of the roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, as well as its implications in memory and neurodegenerative diseases. m^(6)A has demonstrated divergent effects on the proliferation and differentiation of neural stem cells. These observed contradictions may arise from the time-specific nature of m^(6)A and its differential impact on neural stem cells across various stages of development. Similarly, the diverse effects of m^(6)A on distinct types of memory could be attributed to the involvement of specific brain regions in memory formation and recall. Inconsistencies in m^(6)A levels across different models of neurodegenerative disease, particularly Alzheimer's disease and Parkinson's disease, suggest that these disparities are linked to variations in the affected brain regions. Notably, the opposing changes in m^(6)A levels observed in Parkinson's disease models exposed to manganese compared to normal Parkinson's disease models further underscore the complexity of m^(6)A's role in neurodegenerative processes. The roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, and its implications in memory and neurodegenerative diseases, appear contradictory. These inconsistencies may be a

关键词： Alzheimer's disease cell self-renewal central nervous system memory microglia nerve regeneration neurodegenerative diseases neurogenesis RNA methylation

HOMOgeNEOUS ENZYME IMMUNOASSAY OF SERUM AFP BY FLUORIMETRIC KINETIC METHOD

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Chinese Chemical Letters 1993年第4期4卷 353-354页

作者： qing ge li Yi Bing ZHAO Jin Gou XU Xian Zhi HUANG Guo Zhen CHEN Department of Chemistry,Xiamen University,Xiamen,361005

The activity of the Ab-bound enzyme(HRP)changed after immunochemical reaction,and can be indicated by a sensitive fluorimetric kinetic *** finding set the stage for developing sensitive homogeneous *** was measured as... 详细信息

关键词： AFP HRP HVA HOMOgeNEOUS ENZYME IMMUNOASSAY OF SERUM AFP BY FLUORIMETRIC KINETIC METHOD

Effect of pyrite content on chalcopyrite flotation under different regrinding conditions

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 49-57页

作者： Zejun Wang qing Shi Guofan Zhang Yuxuan Zhu Binbin li School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China Key Laboratory of Hunan Province for Clean and Efficient Utilization of Strategic Calcium-containing Mineral Resources Central South UniversityChangsha 410083China

This study aimed to investigate the effect of varying pyrite(Py)content on copper(Cu)in the presence of different regrinding conditions,which were altered using different types of grinding media:iron,ceramic balls,and their mixture,followed by flotation in the cleaner *** flotation performance of rough Cu concentrate can be improved by changing the regrinding conditions based on the Py *** electron microscopy,X-ray spectrometry,ethylenediaminetetraacetic acid disodium salt extraction,and X-ray photoelectron spectroscopy studies illustrated that when the Py content was high,the use of iron media in regrinding promoted the generation of hydrophilic Fe OOH on the surface of Py and improved the Cu *** ceramic medium with a low Py content prevented excessive Fe OOH from covering the surface of chalcopyrite(Cpy).Electrochemical studies further showed that the galvanic corrosion current of Cpy-Py increased with the addition of Py and became stronger with the participation of iron media.

关键词： chalcopyrite regrinding media pyrite galvanic corrosion flotation

Modular assembly of Co4-thiacalix[4]arene units and Keggin-type SiW12O40 for visible-light photothermal conversion

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Tungsten 2025年第1期7卷 112-119页

作者： Jia-Hui li qing Zhao Dong-Ao Mao Kun Zhou Bao-Kuan Chen Yan-Feng Bi School of Petrochemical Engineering Liaoning Petrochemical University

The construction of metal-organic coordination clusters（MCCs） using modular secondary building units is an important method for preparing functional *** this study,two new MCCs modularly assembled from Keggin-type {SiW12O40}H4TC4A=p-tert-Butylthiacalix[4]arene(SiW12) units and thiacalixarene-supported Co4-thiacalix[4]arene(Co4-TC4A polynuclear second-building units（PSBUs,H4TC4A=p-tert-Butylthiacalix[4]arene） are *** two MCCs,abbreviated as Co4-SiW12and Co8-SiW12,were structurally characterized by single-crystal X-ray *** Co4-SiW12is a supramolecular structure involving cation-anion interactions between Co4-TC4A PSBUs and ***8-SiW12features "barbell-like" shapes with two Co4-TC4A coordinatively linked to a Keggin-type SiW12unit on opposite via W-O_t-Co *** coordination of Co4-TC4A to SiW12in Co8-SiW12resulted in significantly improved photothermal conversion performances compared with Co4-SiW12and pure SiW12or ***-gap determination and photophysical analysis combined with density functional theory calculations indicated the binding mode between Co4-TC4A PSBUs and SiW12,which considerably influences the way of electron transport and the conversion ability of visible light to heat.

关键词： Modular construction Photothermal conversion Polyoxometalate Thiacalixarene

An Improved Practical Byzantine Fault-Tolerant Algorithm Based on XGBoost Grouping for Consortium Chains

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Computers, Materials & Continua 2025年第1期82卷 1295-1311页

作者： Xiaowei Wang Haiyang Zhang Jiasheng Zhang Yingkai ge Kexin Cui Zifu Peng Zhengyi li lihua Wang College of Electronic and Information Engineering Shandong University of Science and TechnologyQingdao266590China

In response to the challenges presented by the unreliable identity of the master node,high communication overhead,and limited network support size within the Practical Byzantine Fault-Tolerant(PBFT)algorithm for consortium chains,we propose an improved PBFT algorithm based on XGBoost grouping called XG-PBFT in this ***-PBFT constructs a dataset by training important parameters that affect node performance,which are used as classification indexes for *** XGBoost algorithm then is employed to train the dataset,and nodes joining the system will be grouped according to the trained grouping *** them,the nodes with higher parameter indexes will be assigned to the consensus group to participate in the consensus,and the rest of the nodes will be assigned to the general group to receive the consensus *** order to reduce the resource waste of the system,XG-PBFT optimizes the consensus protocol for the problem of high complexity of PBFT ***,we evaluate the performance of *** experimental results show that XG-PBFT can significantly improve the performance of throughput,consensus delay and communication complexity compared to the original PBFT algorithm,and the performance enhancement is significant compared to other algorithms in the case of a larger number of *** results demonstrate that the XG-PBFT algorithm is more suitable for large-scale consortium chains.

关键词： Consortium chain PBFT grouping reputation XGBoost

Trinuclear gold-catalyzed site-selective alkylation of peptides

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Science China Chemistry 2025年第1期68卷 249-256页

作者： qing-Yun Fang Chengyihan Gu Yinghan Chen Wencheng Yan Yong liang Weipeng li Chengjian Zhu Jie Han Jin Xie State Key Laboratory of Coordination Chemistry Jiangsu Key Laboratory of Advanced Organic Materials Chemistry and Biomedicine Innovation Center (Chem BIC) School of Chemistry and Chemical Engineering Nanjing University Green Catalysis Center College of Chemistry Zhengzhou University State Key Laboratory of Natural Medicines China Pharmaceutical University

Selective modification of peptides has always been a challenging issue. The selective alkylation of peptides can alter the biological activity and physical properties of molecules, and it has gained significant research interest. We herein disclose an intriguing gold-catalyzed alkylation of peptides using bench-stable unactivated alkyl bromides under photoredox catalysis. A wide range of structurally diverse primary, secondary and tertiary alkyl bromides serve as effective coupling partners to precisely connect with the α-C(sp3)–H in glycine residue of peptides. This protocol demonstrates an exceptionally broad scope for alkyl halides and excellent tolerance for a wide range of useful functional groups. A series of relay transformations to construct cyclic peptides, to proceed click reaction and to realize peptide fluorescence labeling further enhance its synthetic practicality. In addition, mechanistic studies and density functional theory(DFT) calculations reveal an inner-sphere and subsequent outersphere single electron transfer(SET) mechanism.

关键词： gold catalysis peptide alkylation C-C coupling radical

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Buried interface bridging for inverted cesium-formamidinium triiodide perovskite solar cells with long operational stability

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Science China Chemistry 2025年第1期68卷 163-173页

作者： Chenhui Zhang Chunjun liang Fulin Sun Ting Zhu Xinghai Huang Yuzhu Guo Xinyu Guo Kunyang ge Dan li Fangtian You Zhiqun He Key Laboratory of Luminescence and Optical Information Ministry of Education Institute of Optoelectronic TechnologyBeijing Jiaotong University Department of Physics School of Physical Science and Engineering Beijing Jiaotong University

In the field of perovskite solar cells(PSCs), the research on defects in the buried interface has been relatively limited due to its non-exposure; however, this interface significantly impacts the performance enhancement of inverted PSCs. This study employs phenylethylammonium chloride(PEACl) molecules as a buffer layer to modify the buried interface of p-i-n structured PSCs,aiming to enhance the uniformity of self-assembled monolayers(SAMs) and facilitate the uniform nucleation and growth of perovskite films on the substrate. Furthermore, the introduction of the PEACl buffer layer effectively passivates defects at the bottom of the perovskite layer and notably enhances the crystal quality of the perovskite film by mitigating residual stress,thereby reducing nonradiative recombination loss. Following these optimizations, the MA-free PSCs treated with PEACl achieve a power conversion efficiency(PCE) of 24.11%, with significant improvements in storage, thermal stability, and operational stability. Particularly noteworthy is the device's performance in an unencapsulated state, whereas after 1,500 hours of continuous light operation stability testing, it retains 97% of its original efficiency. This study not only enriches the systematic understanding of the characteristics of the buried interface in PSCs but also contributes significantly to advancing the commercial production of perovskite photovoltaic technology.

关键词： defect-induced recombination buried interfaces inverted perovskite solar cells crystallization lattice mismatch

联合筋膜鞘悬吊术和额肌瓣悬吊术治疗中重度上睑下垂的疗效比较

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国际眼科杂志 2017年第9期17卷 1790-1792页

作者：赵英年葛洪刚沈清俐中航哈尔滨二四二医院医疗美容科中国黑龙江省哈尔滨市150066

目的:比较联合筋膜鞘悬吊术和额肌瓣悬吊术治疗中重度上睑下垂的临床疗效。方法:回顾性分析2013-03/2016-03在我院进行治疗的46例68眼中重度上睑下垂患者的临床资料,根据手术方法的不同分为研究组(23例34眼)和对照组(23例34眼),研究组... 详细信息

目的:比较联合筋膜鞘悬吊术和额肌瓣悬吊术治疗中重度上睑下垂的临床疗效。方法:回顾性分析2013-03/2016-03在我院进行治疗的46例68眼中重度上睑下垂患者的临床资料,根据手术方法的不同分为研究组(23例34眼)和对照组(23例34眼),研究组行联合筋膜鞘悬吊术(conjoint fascial sheath,CFS),对照组行额肌瓣悬吊术,对两组患者上睑下垂矫正程度、上睑回退情况、满意度和并发症发生情况进行比较。结果:研究组治疗中重度上睑下垂的正矫率高于对照组,差异有统计学意义(P<0.05)。治疗后研究组上睑回量明显低于对照组,差异有统计学意义(P<0.05)。研究组对治疗的满意度高于对照组,差异有统计学意义(P<0.05)。研究组并发症发生率明显低于对照组,差异有统计学意义(P<0.05)。结论:联合筋膜鞘悬吊术治疗中重度上睑下垂具有很高的矫正率,并具有创伤小、并发症少和可重复性强等优点。

关键词：上睑下垂联合筋膜鞘悬吊术额肌瓣悬吊术