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Neutralizing antibodies against SARS-CoV-2 virus after vaccination in patients with neurofibromatosis type 1

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Signal Transduction and Targeted Therapy 2023年第7期8卷 3215-3217页

作者： Qiao-ling Ruan Zhi-chao Wang Cheng-jiang Wei Wei Wang qing-luan Yang Jing Wu Yan-min Wan ling-ling Ge Wen-hong Zhang qing-feng li Department of Infectious Diseases National Medical Center for Infectious DiseasesShanghai Key Laboratory of Infectious Diseases and Biosafety Emergency ResponseHuashan HospitalFudan UniversityShanghaiPeople’s Republic of China Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghaiPeople’s Republic of China Shanghai Huashen Institute of Microbes and Infections ShanghaiPeople’s Republic of China

Dear Editor,The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has triggered a COVID-19 pandemic that has caused high morbidity and mortality worldwide.1 COVID-19 vaccines are urgently needed to protect all susceptible populations from SARS-CoV-2 *** type 1(NF1)is a hereditary dominant disease that affects approximately one in every 3000 newborns.

关键词： mortality acute respiratory

Complement components of nerve regeneration conditioned fluid influence the microenvironment of nerve regeneration

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Neural Regeneration Research 2016年第4期11卷 682-686页

作者： Guang-shuai li qing-feng li Ming-min Dong Tao Zan Shuang Ding lin-bo liu Plastic&Reconstructive Surgery of the First Affiliated Hospital of Zhengzhou University ZhengzhouHenan ProvinceChina Plastic&Reconstructive Surgery of the Ninth People's Hospital Affiliated to Shanghai Jiaotong University ShanghaiChina Otolaryngology-Head&Neck Surgery of the First Affiliated Hospital of Zhengzhou University ZhengzhouHenan ProvinceChina

Nerve regeneration conditioned fluid is secreted by nerve stumps inside a nerve regeneration chamber.A better understanding of the proteinogram of nerve regeneration conditioned fluid can provide evidence for studying the role of the microenvironment in peripheral nerve *** this study,we used cylindrical silicone tubes as the nerve regeneration chamber model for the repair of injured rat sciatic *** tags for relative and absolute quantitation proteomics technology and western blot analysis confirmed that there were more than 10 complement components（complement factor I,C1q-A,C1q-B,C2,C3,C4,C5,C7,C8β and complement factor D） in the nerve regeneration conditioned fluid and each varied at different time *** findings suggest that all these complement components have a functional role in nerve regeneration.

关键词： nerve regeneration peripheral nerve injury nerve regeneration chamber model sciatic nerve nerve regeneration conditioned fluid complement i TRAQ proteomics technology neural regeneration

Correction to:Machine learning the nuclear mass

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Nuclear Science and Techniques 2021年第11期32卷 13-14页

作者： Ze-Peng Gao Yong-Jia Wang Hong-liang Lu qing-feng li Cai-Wan Shen ling liu College of Physics Science and Technology Shenyang Normal UniversityShenyang 110034China School of Science Huzhou UniversityHuzhou 313000China HiSilicon Research Department Huawei Technologies Co.Ltd.Shenzhen 518000China Institute of Modern Physics Chinese Academy of ScienceLanzhou 730000China

Following publication of the original article,Formula(2)is missing and Fig.11,Fig.9 are *** original article has been corrected and the Publisher apologized to the authors and the readers for the inconve-nience caused... 详细信息

关键词： identical corrected mass

In vitro cultivation and differentiation of fetal liver stem cells from mice

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Cell Research 2005年第5期15卷 401-405页

作者： Ren qing feng*, li Ying DU, Zhen Quan GUO College of life Sciences, Peking University, Beijing 100871, China CollegeoflifeSciences PekingUniversityBeijing100871China

During embryonic development, pluripotent endoderm tissue in the developing foregut may adopt pancreatic fate or hepatic fate depending on the activation of key developmental regulators. Transdifferentiation occurs between hepato- cytes and pancreatic cells under specific conditions. Hepatocytes and pancreatic cells have the common endodermal progenitor cells. In this study we isolated hepatic stem/progenitor cells from embryonic day (ED) 12-14 Kun-Ming mice with fluorescence-activated cell sorting (FACS). The cells were cultured under specific conditions. The cultured cells deploy dithizone staining and immunocytochemical staining at the 15th, 30th and 40th day after isolation. The results indicated the presence of insulin-producing cells. When the insulin-producing cells were transplanted into alloxan- induced diabetic mice, the nonfasting blood glucose level was reduced. These results suggested that fetal liver stem/ progenitor cells could be converted into insulin-producing cells under specific culture conditions. Fetal liver stem/ progenitor cells could become the potential source of insulin-producing cells for successful cell transplantation therapy strategies of diabetes.

关键词： Hepatic stem/progenitor cell diabetes β-cell dithizone staining immunocytochemistry.

Drug resistance and pathogenic spectrum of patients coinfected with nontuberculous mycobacteria and human-immunodeficiency virus in Chengdu, China

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Chinese Medical Journal 2019年第11期132卷 1293-1297页

作者： Dong-Mei Wang Yi liao qing-feng li Ma Zhu Gui-Hui Wu Yuan-Hong Xu Jing Zhong Jia Luo Ying-Jie li Department of Clinical Laboratory Public Health Clinical Center of Chengdu Chengdu Sichuan 610066 China Department of Clinical Laboratory Chengdu Woman's and Children's Central Hospital Chengdu Sichuan 610073 China

Background:Human-immunodeficiency virus (HIV) infection is increasing worldwide and nontuberculous mycobacteria (NTM) is an established microbiologic cause of pulmonary disease,lymphadenitis,and disseminated disease in cases of advanced immune *** on patients coinfected with HIV and NTM are ***,this study aimed to analyze the clinical characteristics,drug resistance,and pathogen spectrum of patients coinfected with both HIV and NTM in the Chengdu area of ***:Data of 59 patients coinfected with both HIV and NTM collected from the Public Health Clinical Center of Chengdu,between January 2014 and December 2018,were *** drug sensitivity testing was performed using the microporous plate ratio *** were analyzed using SPSS 19.0,and the change in drug resistance rate was analyzed using the chi-square (x2) ***:Seven species/complex of NTM were identified from patients coinfected with HIV and NTM in this study,with Mycobacterium avium-intracellulare complex (52.5%) and *** (27.1%) as the predominant *** patients were more affected 50/59 (84.7%);the mean age of the 59 cases was 45 *** clinical characteristics mainly included anemia (86.4%),cough and expectoration (79.7%).The baseline CD4 count was 0.05).Condusions:The immune level of patients coinfected with HIV and NTM is low in advanced AIDS stage;more male are

关键词： Clinical features Drug resistance HIV Mycobacterium avium-intracellulare infection Mycobacterium kansasii Nontuberculous mycobacteria

Water Pollution in the Drainage Canal and in Lake Wuliangsuhai in Hetao Plain of Inner Mongolia

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Water Pollution in the Drainage Canal and in Lake Wuliangsuh...

检测大肠杆菌O157:H7的电化学阻抗谱生物传感器的研究

中国自然资源学会2012学术年会

作者： qing-feng li Jin JING Shu-ying KONG Hong-mei JIA

Water pollution in the drainage canals in the Hetao Plaint has been a serious problem affecting the water quality in the LakeWuliangsuhai,and consequently,threatens the water safety of the Yellow *** effort was made to investigate the pollution features along the main drainage canal and in the *** 5 main water pollution indicators of TN(Total Nitrogen),NH-N(Ammonia Nitrogen),T-P(Total Phosphorus),COD(Chemical Oxygen Depletion) and BOD(Biological Oxygen Depletion) were monitored along the MainDrainageCanal and in the *** concentrations in the Canal and in the Lake were rated as "Heavily Polluted".Neither increasing nor decreasing trend in terms of the pollutant concentration was found along the Canal downstream Pollutant concentrations were high in the inlet area of the Lake,but decreased with the increasing distance from the *** quality was poor in the spring low water period and was improved in the Summer-Automn season when the water volume in the lake was high.

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传感技术学报 2005年第1期18卷 5-9页

作者：张灯陈松月秦利锋李蓉王平 li Yanbin 浙江大学生物传感器国家专业实验室生物医学工程教育部重点实验室生物医学工程与仪器科学学院杭州310027 美国阿肯色大学生物与农业工程系

我们提出了用掺锡的三氧化二铟 (ITO)作为工作电极 ,通过硅烷化固定化技术 ,将抗大肠杆菌O15 7:H7单克隆抗体固定在ITO电极表面 ,利用电化学阻抗谱技术来构建一种新型的免疫传感器。该新型的免疫传感器的检测限为 4× 10 3 CFU/mL ,检... 详细信息

我们提出了用掺锡的三氧化二铟 (ITO)作为工作电极 ,通过硅烷化固定化技术 ,将抗大肠杆菌O15 7:H7单克隆抗体固定在ITO电极表面 ,利用电化学阻抗谱技术来构建一种新型的免疫传感器。该新型的免疫传感器的检测限为 4× 10 3 CFU/mL ,检测线性范围为 4× 10 3 - 4× 10 6CFU/mL。实验研究表明 ,该传感器具有灵敏度较高 ,检测时间短 ,操作简单等优点 ,在临床医学和环境监测中具有应用价值。

关键词：电化学阻抗谱免疫生物传感器大肠杆菌检测

Influence of hinge position on the effectiveness of open-door expansive laminoplasty for cervical spondylotic myelopathy

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Chinese Journal of Traumatology 2011年第1期14卷 36-41页

作者： WAN Jun XU Tian-tong SHEN qing-feng li Hui-nan XIA Ying-peng Department of Orthopaedic Surgery Tianjin Union Medicine Center Tianjin China

Objective： To assess the influence of different hinge positions on clinical results of expansive open-door laminoplasty （EOLP） for cervical spondylotic myelopathy （CSM）.Methods： A total of 102 CSM patients who underwent EOLP from February 2006 to February 2007 were enrolled in this randomized controlled trial. Using a random digits table,57 patients with the hinge located at the inner margin of the lateral mass were classified as wide-open group, while 45 patients with the hinge positioned at the lamina margin served as narrow-open group. All patients were observed over 24 months, and the clinical and radiological results were analyzed ***： There were no significant differences in operation duration, intraoperative bleeding volume, Japanese Orthopaedic Association （JOA） scores, cervical curvature index, range of motion and neural function recovery *** neural functions were satisfactorily improved after surgery in both groups, while the severity of axial symptoms was significantly lower in the narrow-open group than in the wide-open group （P=0.003）. The incidence of C5 palsy in the wide-open group was higher than that in the narrowopen group （5.3% vs 0）, even though the difference did not reach statistical significance （one tailed Fisher＇s exact test,P=0.17）.Conclusions： Proper inward shift of the hinge can ensure effectiveness of surgical decompression, avoid an excessive backward shift of the spinal cord, decrease the incidence of C5 palsy and alleviate the severity of axial symptoms.

关键词： Cervical vertebrae Spinal cord diseases Spondylosis Surgical procedures,operative

Direct synthesis of high thermally stable and temperature-sensing lanthanide coordination polymers with Na-atom as a bridging unit

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Direct synthesis of high thermally stable and temperature-se...