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Lepton-Flavor Violating Processes li → ljγ in Topcolor-Assisted Technicolor Models

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Communications in Theoretical Physics 2002年第10期38卷 461-464页

作者： YUE Chong-Xing XU qing-jun LIU guo-Li CCAST World Laboratory P.O. Box 8730 Beijing 100080 China College of Physics and Information Engineering Henan Normal University Xinxiang 453002 China College of Physics and Information Engineering Henan Normal University Xinxiang 453002 China College of Physics and Information Engineering Henan Normal University Xinxiang 453002 China

We consider the lepton-flavor violating (LFV) processes li → ljγ in the framework of topcolor-assistedtechnicolor (TC2) models. We find that the new gauge boson Z' predicted by TC2 models can give significantlycontributions to these processes via the flavor-changing couplings Z'lilj. The present experimental bound on the LFVprocess μ→ eγ gives severe constraints on the TC2 models. Using other experimental constraints on the Z' mass Mz,we obtain constraints on the lepton mixing factors KTμ and KTe. The future LFV experiments will probe into TC2models.

关键词： lepton flavor, topcolor-assisted technicolor (TC2)

Complex liver retransplantation to treat graft loss due to long-term biliary tract complication after liver transplantation: A case report

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World Journal of Clinical Cases 2020年第3期8卷 568-576页

作者： Jiang Li qing-jun guo Wen-Tao Jiang Hong Zheng Zhong-Yang Shen Department of Liver Transplant Tianjin First Central Hospital

BACKGROUND Loss of graft function after liver transplantation(LT) inevitably requires liver retransplant. Retransplantation of the liver(Re LT) remains controversial because of inferior outcomes compared with the primary orthotopic LT(OLT).Meanwhile, if accompanied by vascular complications such as arterial and portal vein(PV) stenosis or thrombosis, it will increase difficulties of surgery. We hereby introduce our center’s experience in Re LT through a complicated case of *** SUMMARY We report a patient who suffered from hepatitis B-associated cirrhosis and underwent LT in December 2012. Early postoperative recovery was *** months after LT, the patient’s bilirubin increased significantly and he was diagnosed with an ischemic-type biliary lesion caused by hepatic artery occlusion. The patient underwent percutaneous transhepatic cholangial drainage and repeatedly replaced intrahepatic biliary drainage tube regularly for 5 *** patient developed progressive deterioration of liver function and underwent liver re-transplant in January 2019. The operation was performed in a classic OLT manner without venous bypass. Both the hepatic artery and PV were occluded and could not be used for anastomosis. The donor PV was anastomosed with the recipient’s left renal vein. The donor hepatic artery was connected to the recipient’s abdominal aorta. The bile duct reconstruction was performed in an end-to-end manner. The postoperative process was very uneventful and the patient was discharged 1 mo after *** With the development of surgical techniques, portal thrombosis and arterial occlusion are no longer contraindications for ReLT.

关键词： Liver retransplantation Biliary tract complication Ischemic type biliary lesion Portal vein thrombosis Arterial occlusion Graft liver failure Case report

Simultaneous partial splenectomy during liver transplantation for advanced cirrhosis patients combined with severe splenomegaly and hypersplenism

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World Journal of Gastroenterology 2021年第7期27卷 654-665页

作者： Wen-Tao Jiang Jian Yang Yan Xie qing-jun guo Da-Zhi Tian jun-Jie Li Zhong-Yang Shen Department of Liver Transplantation Tianjin First Center HospitalFirst Clinical Institute of Tianjin Medical UniversityTianjin 300192China Organ Transplantation Center Tianjin First Center HospitalTianjin 300192China Department of Hepatological Surgery Zibo Central HospitalZibo 255000Shandong ProvinceChina

BACKGROUND The most effective treatment for advanced cirrhosis and portal hypertension is liver transplantation(LT).However,splenomegaly and hypersplenism can persist even after LT in patients with massive *** To examine the feasibility of performing partial splenectomy during LT in patients with advanced cirrhosis combined with severe splenomegaly and *** Between October 2015 and February 2019,762 orthotopic LTs were performed for patients with end-stage liver diseases in Tianjin First Center ***-four cases had advanced cirrhosis combined with severe splenomegaly and *** these patients,41 received partial splenectomy during LT(PSLT group),and 43 received only LT(LT group).Patient characteristics,intraoperative parameters,and postoperative outcomes were retrospectively analyzed and compared between the two *** The incidence of postoperative hypersplenism(2/41,4.8%)and recurrent ascites(1/41,2.4%)in the PSLT group was significantly lower than that in the LT group(22/43,51.2%;8/43,18.6%,respectively).Seventeen patients(17/43,39.5%)in the LT group required two-stage splenic embolization,and further splenectomy was required in 6 of *** operation time and intraoperative blood loss in the PSLT group(8.6±1.3 h;640.8±347.3 mL)were relatively increased compared with the LT group(6.8±0.9 h;349.4±116.1 mL).The incidence of postoperative bleeding,pulmonary infection,thrombosis and splenic arterial steal syndrome in the PSLT group was not different to that in the LT group,*** Simultaneous PSLT is an effective treatment and should be performed in patients with advanced cirrhosis combined with severe splenomegaly and hypersplenism to prevent postoperative persistent hypersplenism.

关键词： Liver transplantation Partial splenectomy Hypersplenism Splenomegaly Liver cirrhotic Megalosplenia

Simultaneous liver, pancreas-duodenum and kidney transplantation in a patient with hepatitis B cirrhosis, uremia and insulin dependent diabetes mellitus

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World Journal of Gastroenterology 2017年第45期23卷 8104-8108页

作者： Jiang Li qing-jun guo Jin-Zhen Cai Cheng Pan Zhong-Yang Shen Wen-Tao Jiang Department of Liver Transplant Tianjin First Central Hospital Department of Transplant Surgery Tianjin First Central Hospital

Simultaneous liver,pancreas-duodenum,and kidney transplantation has been rarely reported in the literature. Here we present a new and more efficient en bloc technique that combines classic orthotopic liver and pancreas-duodenum transplantation and heterotopic kidney transplantation for a male patient aged 44 years who had hepatitis B related cirrhosis,renal failure,and insulin dependent diabetes mellitus(IDDM). A quadruple immunosuppressive regimen including induction with basiliximab and maintenance therapy with tacrolimus,mycophenolate mofetil,and steroids was used in the early stage post-transplant. Postoperative recovery was uneventful and the patient was discharged on the 15 th postoperative day with normal liver and kidney function. The insulin treatment was completely withdrawn 3 wk after operation,and the blood glucose level remained normal. The case findings support that abdominal organ cluster and kidney transplantation is an effective method for the treatment of end-stage liver disease combined with uremia and IDDM.

关键词： Insulin dependent diabetes mellitus Cirrhosis Chronic renal failure Transplantation En bloc Liver-pancreas

Effects of positive acceleration(+Gz stress) on liver enzymes,energy metabolism,and liver histology in rats

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World Journal of Gastroenterology 2019年第3期25卷 346-355页

作者： Bin Shi Xian-Qiang Wang Wei-Dong Duan guo-Dong Tan Han-Jing Gao Ying-Wei Pan qing-jun guo Hong-Yi Zhang Department of Hepatobiliary Surgery Air Force Medical Center PLA Department of Pediatrics Chinese PLA General Hospital and PLA Medical School Department of Hepatobiliary Surgery Chinese PLA General Hospital and PLA Medical School Outpatient Department Air Command Headquarters Department of Ultrasound Chinese PLA General Hospital and PLA Medical School Department of Endocrinology Changhai Hospital Second Military Medical University

BACKGROUND Exposure to high sustained +Gz(head-to-foot inertial load) is known to have harmful effects on pilots' body in flight. Although clinical data have shown that liver dysfunction occurs in pilots, the precise cause has not been well *** To investigate rat liver function changes in response to repeated +Gz *** Ninety male Wistar rats were randomly divided into a blank control group(BC group, n = 30), a +6 Gz/5 min stress group(6 GS group, n = 30), and a +10 Gz/5 min stress group(10 GS group, n = 30). The 6 GS and 10 GS groups were exposed to +6 Gz and +10 Gz, respectively, in an animal centrifuge. The onset rate of +Gz was 0.5 G/s. The sustained time at peak +Gz was 5 min for each exposure(for 5 exposures, and 5-min intervals between exposures for a total exposure and non-exposure time of 50 min). We assessed liver injury bymeasuring the portal venous flow volume, serum alanine aminotransferase(ALT)and aspartate aminotransferase(AST), liver tissue malondialdehyde(MDA), Na+-K+-ATPase, and changes in liver histology. These parameters were recorded at 0 h, 6 h, and 24 h after repeated +Gz *** After repeated +Gz exposures in the 6 GS and the 10 GS groups, the velocity and flow signal in the portal vein(PV) were significantly decreased as compared to the BC group at 0 h after exposure. Meanwhile, we found that the PV diameter did not change significantly. However, rats in the 6 GS group had a much higher portal venous flow volume than the 10 GS group at 0 h after exposure. The 6 GS group had significantly lower ALT, AST, and MDA values than the 10 GS group 0 h and 6 h post exposure. The Na^+-K^+-ATPase activity in the 6 GS group was significantly higher than that in the 10 GS group 0 h and 6 h post *** injury, determined pathologically, was significantly lower in the 6 GS group than in the 10 GS *** Repeated +Gz exposures transiently cause hepatocyte injury and affect liver metabolism and morphologica

关键词： Positive acceleration +Gz Liver function Animal models Liver metabolism Ischemia-reperfusion injury

Liver transplantation for a giant mesenchymal hamartoma of the liver in an adult: Case report and review of the literature

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World Journal of Gastroenterology 2015年第20期21卷 6409-6416页

作者： Jiang Li Jin-Zhen Cai qing-jun guo jun-Jie Li Xiao-Ye Sun Zhan-Dong Hu David KC Cooper Zhong-Yang Shen Department of Transplant Surgery Tianjin First Central Hospital Department of Pathology Tianjin First Central Hospital Thomas E Starzl Transplantation Institute University of Pittsburgh

Mesenchymal hamartomas of the liver(MHLs) in adults are rare and potentially premalignant lesions, which present as solid/cystic neoplasms. We report a rare case of orthotopic liver transplantation in a patient with a giant MHL. In 2013, a 34-year-old female sought medical advice after a 2-year history of progressive abdominal distention and respiratory distress. Physical examination revealed an extensive mass in the abdomen. Computed tomography(CT) of her abdomen revealed multiple liver cysts, with the diameter of largest cyst being 16 cm × 14 cm. The liver hilar structures were not clearly displayed. The adjacent organs were compressed and displaced. Initial laboratory tests, including biochemical investigations and coagulation profile, were unremarkable. Tumor markers, including levels of AFP, CEA and CA19-9, were within the normal ranges. The patient underwent orthotopic liver transplantation in November 2013, the liver being procured from a 40-year-old man after cardiac death following traumatic brain injury. Warm ischemic time was 7.5 min and cold ischemic time was 3 h. The recipient underwent classical orthotopic liver transplantation. The recipient operative procedure took 8.5 h, the anhepatic phase lasting for 1 h without the use of venovenous bypass. The immunosuppressive regimen includedintraoperative induction with basiliximab and high-dose methylprednisolone, and postoperative maintenance with tacrolimus, mycophenolate mofetil, and prednisone. The recipient's diseased liver weighed 21 kg(dry weight) and measured 41 cm × 32 cm × 31 cm. Histopathological examination confirmed the diagnosis of an MHL. The patient did not experience any acute rejection episode or other complication. All the laboratory tests returned to normal within one month after surgery. Three months after transplantation, the immunosuppressive therapy was reduced to tacrolimus monotherapy, and the T-tube was removed after cholangiography showed no abnormalities. Twelve months after tran

关键词： Liver Mesenchymal hamartoma Adult Organ donor After cardiac death Transplantation

Identification of villous M cells in the small intestine of newborn piglets

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Identification of villous M cells in the small intestine of ...

Ancient Art Retains Splendor in New Era

第十届全国免疫学学术大会

作者： Ren-Feng LI Yan-Yan YANG Song-Lin QIAO jun-qing guo Gai-Ping ZHANG College of Veterinary Medicine Northwest A & F University College of Veterinary Medicine Henan Institute of Science and Technology Key Laboratory of Animal Immunology of the Ministry of Agriculture Henan Provincial Key Laboratory of Animal Immunology Henan Academy of Agricultural Sciences College of Animal Science and Veterinary Medicine Henan Agricultural University

0bjective:Microfold(M)cells,as an important part of intestinal mucosal immune system,act as antigen-sampling sites for initiating antigen specific mucosal immune responses,but they also provide a gateway for enteropathogen *** aim of this study was to determine the distribution characteristics and morphological ***:The distribution characteristics and morphological features of villous M in newborn piglets’small intestine were determined by immunohistochemical(IHC)and morphological ***:These villous M cells,with dark apical membrane,possessed markedly blunted and reduced numbers of microvilli,and had a slightly depressed surface compared to neighboring villous epithelial *** villous M cells in duodenum and mid-jejunum were mostly columnar in shape and the ileal villous M cells exhibited more pocket-like *** showed that the ileum had significantly increased number(Pjunum,and a gradually decreased density of M cells from lower crypt epithelium to upper villous ***:This study demonstrated the presence of,intestinal villous M cells in the newborn piglets,with variable morphology and distribution pattern in the different regions of the small intestine.

关键词： Microfold Cells Newborn Piglets Immunohistochemical Morphological

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China Today 2025年第1期74卷 74-75页

作者： guo qing 不详

With government support,more young people are studying Thangka art,securing its innovative *** 1,300-year-old Thangka art,religious painting on woven material,has been lauded as an illustrated encyclopedia of Tibetan *** unique artistic and cultural value earned it a place on China’s intangible cultural heritage list in *** institution tasked with preserving and developing this ancient art is the Tibet Academy of Thangka(TAT)in *** focuses on the Mansar School of Thangka *** can observe the whole process of creating a Mansar Thangka piece,from sketching to adding the final touch.

关键词： religious earned sketch

China-India: Ties that Bind

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China Today 2025年第1期74卷 59-61页

作者： guo qing 不详

From international student to professor,Tripathi Mani shares his thoughts on Chinese and Indian cultures and the beneficial exchanges between *** Vivek Mani first learned about China from bedtime stories told by his father,a Sanskrit teacher in rural Bihar,a state in east *** of the stories were about the Chinese monk Xuanzang’s adventures during his long journey to India to find Buddhist *** kindled the young boy’s interest in China and the desire to visit it one day.

关键词： India Indian desire