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Angiography-derived radial wall strain predicts coronary lesion progression in non-culprit intermediate stenosis

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Journal of Geriatric Cardiology 2022年第12期19卷 937-948页

作者： Zhi-qing WANG Bo XU Chun-Ming LI Chang-Dong GUAN Yue CHANG Li-hua XIE Su ZHANG Jia-Yue huaNG Patrick W Serruys William Wijns Liang-Long CHEN Sheng-Xian TU Department of Cardiology Fujian Heart Medical CenterFujian Institute of Coronary Heart DiseaseFujian Medical University Union HospitalFujianChina Biomedical Instrument Institute School of Biomedical EngineeringShanghai Jiao Tong UniversityShanghaiChina Department of Cardiology National Clinical Research Center for Cardiovascular DiseasesFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina The Lambe Institute for Translational Medicine and Curam University of GalwayGalwayIreland

BACKGROUND Intermediate coronary lesions(ICLs)are highly prevalent but ported mixed *** strain has been associated with plaque vulnerability,yet its role in predicting lesion progression is largely *** purpose of this study was to determine the predictive value of angiography-derived radial wall strain(RWS)for progression of untreated non-culprit *** Post-hoc analysis was conducted in a study cohort including 603 consecutive patients with 808 ICLs identified at index procedure with angiographic follow-up of up to two *** analysis was performed on selected angiographic frames with minimal foreshortening and vessel *** progression was defined as≥20%increase in percent diameter *** Lesion progression occurred in 49 ICLs(6.1%)with a median follow-up period of 16.8 *** RWS(RWSmax),frequently located at the proximal and throat plaque regions,distinguished progressive ICLs from silent *** largest area under the curve value of 0.75(95%CI:0.67–0.82,P12.6%.According to this threshold,178 ICLs were classified as having a high strain *** to a high strain amplitude with RWS_(max)>12.6%was independently associated with an increased risk of lesion progression(adjusted HR=6.82,95%CI:3.67–12.66,P<0.001).CONCLUSIONS Assessment of RWS from coronary angiography is feasible and provides independent prognostic value in patients with untreated ICLs.

关键词： coronary stenosis strain

Modular Synthesis of Ir（Phox）-Cored Dendritic Catalysts and Their Application in Asymmetric Hydrogenation of 2, 4-Diaryl-1, 5- Benzodiazepines: A Strong Positive Dendritic Effect on Catalytic Activity

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Modular Synthesis of Ir（Phox）-Cored Dendritic Catalysts an...

Microstructures and mechanical properties of AZ91D/0Cr19Ni9 bimetal composite prepared by liquid-solid compound casting

第十七届全国金属有机化学学术讨论会

作者： Baode Ma qing-hua Fan CAS Key Laboratory of Molecular Recognition and Function Institute of ChemistryChinese Academy of Sciences （CAS）

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Transactions of Nonferrous Metals Society of China 2019年第1期29卷 51-58页

作者： Jian-hua ZHAO Wen-qun ZHAO Shen QU Yan-qing ZHANG State Key Laboratory of Mechanical Transmission Chongqing University Chongqing 400044 China College of Materials Science and Engineering Chongqing University Chongqing 400044 China

The liquid-solid compound casting technology was used to produce the AZ91D/0Cr19Ni9 bimetal composite without and with hot dipping aluminium, respectively. The influences of Al coating on microstructures and mechanical properties of AZ91D/0Cr19Ni9 interface were investigated. The results showed that the mechanical bonding was obtained between AZ91D and bare steel 0Cr19Ni9 where a gap existed at the interface; the metallurgical bonding was formed between AZ91D and Al-coated 0Cr19Ni9, which could be divided into two different intermetallic layers: layer Ⅰ was mainly composed of α-Mg+β-Mg17Al12 eutectic structure and a small amount of MgAl2O4, and layer Ⅱ mainly comprised of Fe2Al5 intermetallic compound. Furthermore, the hardness value of interface was obviously higher than that of AZ91D matrix, and the average hardness values of layers Ⅰ and Ⅱ were HV 158 and HV 493, respectively. The shear strength of AZ91D/Al-coated 0Cr19Ni9 interface was higher than that of AZ91D/bare 0Cr19Ni9 interface, which confirmed that Al coating could improve the adhesive strength between AZ91D and 0Cr19Ni9 during liquid-solid compound casting process.

关键词： AZ91D 0Cr19Ni9 liquid-solid compound casting interface bonding shear strength

矿井多波多分量地震勘探超前探测原理与实验研究

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中南大学学报（自然科学版） 2009年第5期40卷 1392-1398页

作者：梁庆华宋劲中南大学信息物理工程学院湖南长沙410083 煤炭科学研究总院重庆研究院重庆400037

为了长距离超前探测煤矿井下的地质构造情况,应用多波多分量地震勘探理论,介绍DTC-150井下长距离超前探测仪的基本原理,研究该仪器的井下测量方法与资料处理解释原则,并应用该仪器对不同的矿井进行超前预报探测实验。研究结果表明:采用D... 详细信息

为了长距离超前探测煤矿井下的地质构造情况,应用多波多分量地震勘探理论,介绍DTC-150井下长距离超前探测仪的基本原理,研究该仪器的井下测量方法与资料处理解释原则,并应用该仪器对不同的矿井进行超前预报探测实验。研究结果表明:采用DTC-150井下超前探测仪器能够较准确地探测到掘进面前方100m内断层、围岩裂隙、岩石破碎带以及富水情况,据由该仪器获得的波速对围岩进行分类。

关键词：地震勘探矿井超前探测长距离多波多分量

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基于光纤腔衰落解调技术的光纤光栅传感研究

光电子．激光 2007年第9期18卷 1043-1045,1051页

作者：刘波张键罗建花张卫华史青开桂云南开大学现代光学所光电信息技术教育部重点实验室天津300071 Photonics Research Group ASTON UniversityBirminghamUKB4 7ET

采用弱调制长周期光纤光栅(LPG)作为基本传感器件,将其接入到光纤谐振腔中,利用光纤腔衰落(FRD)技术,通过检测脉冲激光的衰落时间实现光纤光栅传感的波长解调。进行了0～100℃温度和0～1000με应变实验,波长解调范围为10nm。

关键词：光纤腔衰落(FRD) 长周期光纤光栅(LPG) 传感光腔衰落(CRD)

基于HPLC指纹图谱和多组分含量测定结合化学模式识别研究的龙眼核质量评价

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中南药学 2024年第4期22卷 1059-1064页

作者：王艺洁蒋佳丽陈彦洁罗鑫蒋学青王志萍谢谭芳广西中医药大学药学院南宁530200 农作物废弃物功能成分研究协同创新中心南宁530200 广西高校中药制剂共性技术研发重点实验室南宁530200

目的建立龙眼Dimocarpus longan Lour.核HPLC指纹图谱及含量测定方法。方法建立13批龙眼核指纹图谱,结合指纹图谱相似度评价及化学模式识别研究对龙眼核质量进行分析,并测定其中没食子酸、柯里拉京、鞣花酸的含量。结果 13批龙眼核样... 详细信息

目的建立龙眼Dimocarpus longan Lour.核HPLC指纹图谱及含量测定方法。方法建立13批龙眼核指纹图谱,结合指纹图谱相似度评价及化学模式识别研究对龙眼核质量进行分析,并测定其中没食子酸、柯里拉京、鞣花酸的含量。结果 13批龙眼核样品相似度在0.919~0.999,标定共有峰11个,并指认出3种成分;聚类分析(HCA)将13批龙眼核聚为3类,主成分分析(PCA)提取到3个主成分,正交偏最小二乘判别分析(OPLS-DA)筛选出5个差异性成分;定量分析得到13批龙眼核中没食子酸、柯里拉京金、鞣花酸的含量范围依次为0.65~1.8 mg·g^(-1)、3.02~5.46 mg·g^(-1)、3.18~4.49 mg·g^(-1)。结论建立的HPLC指纹图谱及含量测定方法重复性、稳定性良好,能够为龙眼核质量评价提供参考。

关键词：龙眼核指纹图谱化学模式识别研究含量测定

Challenges and strategies in progress of drug delivery system for traditional Chinese medicine Salviae Miltiorrhizae Radix et Rhizoma(Danshen)

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Chinese Herbal Medicines 2021年第1期13卷 78-89页

作者： Ruo-ning Wang hua-cong Zhao Jian-yu huang Hong-lan Wang Jun-song Li Yin Lu Liu-qing Di School of Pharmacy Nanjing University of Chinese MedicineNanjing 210046China Jiangsu Engineering Research Center for Efficient Delivery System of TCM Nanjing 210046China Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica Nanjing 210046China

Traditional Chinese medicines(TCMs), with a history of thousands of years, are widely used clinically with effective treatment. However, the drug delivery systems(DDSs) for TCMs remains major challenges due to the characteristics of multi-components including alkaloids, flavones, anthraquinones, glycosides,proteins, volatile oils and other types. Therefore, the novel preparations and technology of modern pharmaceutics is introduced to improve TCM therapeutic effects due to instability and low bioavailability of active ingredients. Salviae Miltiorrhizae Radix et Rhizoma, the radix and rhizomes of Salvia miltiorrhiza Bunge(Danshen in Chinese), is a well known Chinese herbal medicine for protecting the cardiovascular system, with active ingredients mainly including lipophilic tanshinones and hydrophilic salvianolic *** this review, this drug is taken as an example to present challenges and strategies in progress of DDSs for TCMs. This review would also summary the characteristics of active ingredients in it including physicochemical properties and pharmacological effects. The purpose of this review is to provide inspirations and ideas for the DDSs designed from TCMs by summarizing the advances on DDSs for both singleand multi-component from Danshen.

关键词： active ingredients challenges and strategies drug delivery systems Salvia miltiorrhiza Bunge Salviae Miltiorrhizae Radix et Rhizoma traditional Chinese medicines

An Improved Data Exchange Method Between Pro/E and ADAMS

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International Journal of Plant Engineering and Management 2012年第2期17卷 82-86页

作者： DING Yu HAN Bao-ling luo qing-sheng School of Mechanical Engineering Beijing Institute of Technology Beijing 100081 P. R. China School of Mechatronical Engineering Beijing Institute of Technology Beijing 100081 P. R. China

According to the question of how to transfer data between Pro/E and ADAMS correctly, the paper gives an improved importing solution, which combines the interface and the Standard Data Format（SDF） files. It settles the problems caused by improper geometry during the import conducted by the interface software. With the solution ,fea- ture points can be conveniently picked to build kinematic constraints are the preparation of the model will be simpli- fied. An example is given for the method, and corresponding simulations are conducted. The results of the simula- tions verify the validity of the solution.

关键词： mechanical design and theory technique of simulation three-dimensional modeling data interac-tive solutions

The Mechanism on Cyclization, Debenzylation and Oxidation of 1-[1-(Benzyloxy)-3-methylnaphthalen-4-yloxy]propan-2-one

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Chinese Chemical Letters 2006年第6期17卷 769-772页

作者： Shi Liang huaNG Yi luo Zhi Shu huaNG Xian Zhang BU Pei qing LIU Lin MA Yue Ming LI Albert S. C. CHAN Lian Quan GU School of Chemistry and Chemical Engineering Sun Yat-Sen University Guangzhou 510275 School of Pharmaceutical Science Sun Yat-Sen University Guangzhou 510275 Department of Applied Bioiogy ＆ Chemical Technology The Hong Kong Polytechnic University Kowloon Hong Kong

1-[1-（Benzyloxy）-3-methylnaphthalen-4-yloxy]propan-2-one （la） took place a cyclization, debenzylation and oxidation to form 9-substitued benzo[de]chromene-7,8-dione （2a） and 5-benzyl-9-substitued benzo[de]chrome... 详细信息

关键词： Mansonone F cyclization selenium dioxide sigmatropic rearrangement.