检索结果-南通市图书馆

Changes in the amplitude of low-frequency fluctuations in specific frequency bands in major depressive disorder after electroconvulsive therapy

引用

World Journal of Psychiatry 2022年第5期12卷 708-721页

作者： Xin-Ke Li Hai-Tang Qiu Jia Hu qing-hua luo College of Medical Informatics Chongqing Medical UniversityChongqing 400016China Mental Health Center the First Affiliated Hospital of Chongqing Medical UniversityChongqing Medical UniversityChongqing 400016China Institute for Advanced Studies in Humanities and Social Science Chongqing UniversityChongqing 400044China

BACKGROUND Major depressive disorder(MDD)tends to have a high incidence and high suicide *** therapy(ECT)is currently a relatively effective treatment for ***,the mechanism of efficacy of ECT is still *** To investigate the changes in the amplitude of low-frequency fluctuations in specific frequency bands in patients with MDD after *** Twenty-two MDD patients and fifteen healthy controls(HCs)were recruited to this *** patients received 8 ECT sessions with bitemporal ***-state functional magnetic resonance imaging was adopted to examine regional cerebellar blood flow in both the MDD patients and *** MDD patients were scanned twice(before the first ECT session and after the eighth ECT session)to acquire ***,the amplitude of low-frequency fluctuations(ALFF)was computed to characterize the intrinsic neural oscillations in different bands(typical frequency,slow-5,and slow-4 bands).RESULTS Compared to before ECT(pre-ECT),we found that MDD patients after the eighth ECT(post-ECT)session had a higher ALFF in the typical band in the right middle frontal gyrus,posterior cingulate,right supramarginal gyrus,left superior frontal gyrus,and left angular *** was a lower ALFF in the right superior temporal *** to pre-ECT values,the ALFF in the slow-5 band was significantly increased in the right limbic lobe,cerebellum posterior lobe,right middle orbitofrontal gyrus,and frontal lobe in post-ECT patients,whereas the ALFF in the slow-5 band in the left sublobar region,right angular gyrus,and right frontal lobe was *** contrast,significantly higher ALFF in the slow-4 band was observed in the frontal lobe,superior frontal gyrus,parietal lobe,right inferior parietal lobule,and left angular *** Our results suggest that the abnormal ALFF in pre-and post-ECT MDD patients may be associated with specific frequency bands.

关键词： Electroconvulsive therapy Resting-state functional magnetic resonance imaging Major depressive disorder Amplitude of low-frequency fluctuations Specific frequency bands

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effectiveness of six-step complex decongestive therapy for treating upper limb lymphedema after breast cancer surgery

引用

World Journal of Clinical Cases 2022年第25期10卷 8827-8836页

作者： Hui-Zhen Zhang Qiao-Ling Zhong Hui-Ting Zhang qing-hua luo Hai-Lin Tang Li-Juan Zhang Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaGuangzhou 510060China

BACKGROUND Complex decongestive therapy(CDT)is currently recommended as the standard treatment for *** is a four-step detumescence therapy that can effectively treat upper limb lymphedema after breast cancer surgery,and is considered non-invasive,painless and without side *** To determine the effectiveness of a six-step CDT involving a foam granule bandage for the treatment of upper extremity lymphedema pressure after breast cancer surgical *** The study included 100 patients with upper extremity lymphedema after breast cancer *** surgical methods were mastectomy plus axillary lymph node dissection and breast preservation plus sentinel lymph node *** study population was further divided into the experimental group and control group with 50 cases in each *** control group was given conventional CDT(four-step method),which included skin care,freehand lymphatic drainage,foam granule pressurized bandage,and functional *** the experimental group,a six-step CDT method was applied that involved a foam particle bandage combined with air wave pressure therapy in addition to the four steps of conventional *** in both groups were given one course of treatment daily(20 times),and the changes in body moisture and subjective symptoms were measured before and after treatment,preoperatively and 20 times after *** No statistically significant differences in 50-Hz bioelectrical impedance and extracellular moisture ratio were observed between the two groups before treatment,suggesting comparability of the baseline *** treatment,the 50-Hz bioelectrical impedance of the experimental group was significantly higher than that in the control group,and the extracellular moisture ratio was significantly lower than that in the control group.A comparison of the differences between the two groups before and after treatment indicated that the treatment effect in the experimental group was better than th

关键词： Comprehensive deswelling Foam granule bandage Breast cancer Upper limb lymphedema Air pressure wave therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Long-term results of elective open repair for abdominal aortic aneurysm

引用

Chinese Medical Journal 2006年第9期119卷 762-764页

作者： WU qing-hua luo Xiao-yun KOU Lei Department of Vascular Surgery Beijing Anzhen Hospital of Capital University of Medical Sciences Beijing 100029 China

Abdominal aortic aneurysm （AAA） has a high propensity to rupture. Repair of AAA by conventional surgical replacement with a graft has been the standard of treatment since the mid 1960s. Because of advances in surgical, anaesthetic and intensive care techniques, the outcome of elective open AAA repair has improved constantly. However, with the improvement of endovascular techniques, the role of open repair is being challenged. More and more stents are being deployed in patients because of their less invasive characteristics. We reviewed our ten years of experience with elective open AAA repair and recent papers about endoluminal and open repair for AAA to discuss status and future of open repair for AAA in China.

关键词： abdominal aortic aneurysm operative surgical procedures mortafity complications

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Adhesion Performances Between Two Orthotropic Solids Influenced by Temperature Increment

引用

Acta Mechanica Solida Sinica 2024年第3期37卷 430-443页

作者： qing-Hui luo Yue-Ting Zhou School of Aerospace Engineering and Applied Mechanics Tongji UniversityShanghai200092China

The classical adhesive contact models belong to isothermal adhesion theories,where the effect of temperature on adhesion was ***,a number of experimental results indicated that the adhesion behaviors can be significantly affected by *** this paper,the two-dimensional non-slipping anisothermal adhesion behaviors between two orthotropic elastic cylinders are investigated within the framework of the Johnson-Kendall-Roberts *** stated problem is reduced to the coupled singular integral equations by virtue of the Fourier integral transform,which are solved analytically with the analytical function *** closed-form solutions for the stress fields in the presence of thermoelastic effect are *** stable equilibrium state of contact system is determined by virtue of the Griffith energy *** effect of temperature difference on adhesion behaviors between orthotropic solids is *** is found that the difference between the oscillatory and non-oscillatory solutions increases with increasing the degree of anisotropy of orthotropic *** oscillatory solution cannot be well approximated by the non-oscillatory solution for the orthotropic materials with relatively high anisotropy.

关键词： Adhesive contact Non-slipping JKR model Temperature Griffith energy balance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Performance improvements in complementary metal oxide semiconductor devices and circuits based on fin field-effect transistors using 3-nm ferroelectric Hf_(0.5)Zr_(0.5)O_(2)

引用

Rare Metals 2024年第7期43卷 3242-3249页

作者： Zhao-Hao Zhang Yan-Na luo Gao-Bo Xu Jia-Xin Yao Zhen-hua Wu Hong-Bin Zhao qing-Zhu Zhang hua-Xiang Yin Jun luo Wen-Wu Wang Hai-Ling Tu Integrated Circuit Advanced R&D Center Institute of Microelectronics of Chinese Academy of SciencesBeijing 100029China School of Integrated Circuits University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Advanced Materials for Smart Sensing General Research Institute for Nonferrous MetalsBeijing 100088China

In this work,a conventional HfO_(2) gate dielectric layer is replaced with a 3-nm ferroelectric(Fe) HZO layer in the gate stacks of advanced fin field-effect transistors(FinFETs).Fe-induced characteristics,e.g.,negative drain induced barrier lowering(N-DIBL) and negative differential resistance(NDR),are clearly observed for both p-and n-type HZO-based *** characteristics are attributed to the enhanced ferroelectricity of the 3-nm hafnium zirconium oxide(HZO) film,caused by Al doping from the TiAlC capping *** mechanism is verified for capacitors with structures similar to the *** to the enhanced ferroelectricity and N-DIBL phenomenon,the drain current(I_(DS))of the HZO-FinFETs is greater than that of HfO_(2)-FinFETs and obtained at a lower operating ***,circuits based on HZO-FinFET achieve higher performance than those based on HfO_(2)-FinFET at a low voltage drain(V_(DD)),which indicates the application feasibility of the HZO-FinFETs in the ultralow power integrated circuits.

关键词： FinFET Ferroelectric Hafnium zirconium oxide Subthreshold swing Low power

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Escape probability for isotropic emitters near Kerr black hole with astrometric

引用

Communications in Theoretical Physics 2024年第5期76卷 128-133页

作者： Yu-Xuan Han qing-hua Zhu qing-Guo huang CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesNo.19A Yuquan RoadBeijing 100049China Department of Physics Chongqing UniversityChongqing 401331China School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced Study UCASHangzhou 310024China

The paper investigates the escape probability for isotropic emitters near a Kerr black *** propose a new approach to obtain the escape probability in a general manner,going beyond previous case-by-case *** approach is based on studies of the black hole shadow with astrometric observable and can be applied to emitters with an arbitrary 4-velocities and locations,even to the emitters outside of the equatorial *** also consider representative examples illustrating how escape probabilities vary with distance,velocity,and inclination ***,this new approach provides an effective method for studying escape probabilities near Kerr black holes.

关键词： Kerr black hole photon escape probability isotropic emitters

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Protein Secondary Structure Prediction Using Dynamic Programming

引用

Acta Biochimica et Biophysica Sinica 2005年第3期37卷 167-172页

作者： Jing ZHAO Pei-Ming SONG qing FANG Jian-hua luo School of Life Science & Technology,Shanghai Jiaotong University,Shanghai 200240,China Shanghai Center for Bioinformation and Technology,Shanghai 200235,China Logistical Engineering University,Chongqing 400016,China School of Life Science & Technology Shanghai Jiaotong UniversityShanghai 200240 China Shanghai Center for Bioinformation and TechnologyShanghai 200235 China Logistical Engineering UniversityChongqing 400016 China

In the present paper,we describe how a directed graph was constructed and then searched forthe optimum path using a dynamic programming approach,based on the secondary structure propensity ofthe protein short sequence derived from a training data *** protein secondary structure was thus pre-dicted in this *** average three-state accuracy of the algorithm used was 76.70%.

关键词： directed graph dynamic programming approach protein secondary structure

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Structure and 2p decay mechanism of^(18)Mg

引用

Nuclear Science and Techniques 2024年第6期35卷 145-154页

作者： Long Zhou De-qing Fang Si-Min Wang Hui hua Key Laboratory of Nuclear Physics and Ion-beam Application(MOE) Institute of Modern PhysicsFudan UniversityShanghai 200433China Shanghai Research Center for Theoretical Nuclear Physics NSFC and Fudan UniversityShanghai 200438China School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijing 100871China

The recently discovered,extremely proton-rich nuclide 18 Mg exhibits ground-state decay via two sequential two-proton(2p)emissions through the intermediate nucleus,*** study investigates the structure and the initial 2p decay mechanism of^(18)Mgby examining the density and correlations of the valence protons using a three-body Gamow coupled-channel *** results show that the ground state of^(18)Mgis significantly influenced by the continuum,resulting in a significant s-wave ***,based on the current framework,this does not lead to a significant deviation in mirror symmetry in either the structure or spectroscopy of the 18Mg-18C ***,the time evolution analysis of the^(18)Mgground state suggests a simultaneous 2p emission during the first step of *** observed nucleon-nucleon correlations align with those of the light-mass 2p emitters,indicating a consistent decay behavior within this nuclear region.

关键词： Structure of^(18)Mg Two-proton decay Proton-proton correlation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hydrophobic tag tethering degrader as a promising paradigm of protein degradation:Past,present and future perspectives

引用

Chinese Chemical Letters 2024年第8期35卷 187-200页

作者： Si Ha Jiacheng Zhu hua Xiang Guoshun luo State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry China Pharmaceutical UniversityNanjing 211198China

Small molecule inhibitors have dominated the pharmaceutical landscape for a long time as the primary therapeutic paradigm targeting pathogenic ***,their efficacy heavily relies on the amino acid composition and spatial constitution of proteins,rendering them susceptible to drug resistance and failing to target undruggable *** recent years,the advent of targeted protein degradation(TPD)technology has captured substantial attention from both industry and *** an event-driven mode,TPD offers a novel approach to eliminate pathogenic proteins by promoting their degrada-tion,thus circumventing the limitations associated with traditional small molecule ***-bic tag tethering degrader(HyTTD)technology represents one such TPD approach that is currently in the burgeoning *** employ endogenous protein degradation systems to induce the degrada-tion of target proteins through the proteasome pathway,which displays significant potential for medical *** this review,we provide a comprehensive overview of the development history and the reported mechanism of action of ***,we delve into the physiological roles,structure-activity re-lationships,and medical implications of HyTTDs targeting various disease-associated ***,we propose insights into the challenges that necessitate resolution for the successful development of HyTTDs,with the ultimate goal of initiating a new age of clinical treatment leveraging the immense po-tential of HyTTDs.

关键词： Targeted protein degradation(TPD) Hydrophobic tag Degrader Hydrophobic tag tethering degrader(HyTTD) Targeted therapy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Morphology Study for GeV Emission of Nearby Supernova Remnant G332.5-5.6

引用

Research in Astronomy and Astrophysics 2024年第4期24卷 134-140页

作者： Ming-Hong luo qing-Wen Tang Xiu-Rong Mo Department of Physics School of Physics and Materials ScienceNanchang UniversityNanchang 330031China

A spatial template is important to study nearby supernova remnants(SNRs).For SNR G332.5-5.6,we report a Gaussian disk with a radius of about 1°.06 to be a potential good spatial model in the γ-ray *** this new Gaussian disk,its GeV lightcurve shows a significant variability of about seven *** γ-ray observations of this SNR could be explained well either by a leptonic model or a hadronic model,in which a flat spectrum for the ejected electrons/protons is required.

关键词： ISM:supernova remnants gamma rays:ISM

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：