检索结果-南通市图书馆

Integrating lipidomics and gut microbiota to study the anti-hyperlipidemia effect of Sargentodoxae Caulis extract

Traditional Medicine Research 2025年第1期10卷 1-11页

作者： Xiao-Xiao zhang Li Jia Xiu-Jun Zhan Charity Ngina qing-Rui zhang Xiao-Ge Li Qi-Bao Jiang Shi Bai Miao-Miao Jiang National Key Laboratory of Chinese Medicine Modernization Tianjin University of Traditional Chinese MedicineTianjin 301617China Haihe Laboratory of Modern Chinese Medicine Tianjin 301617China School of Medicine Taizhou UniversityTaizhou 318000China.

Background:Sargentodoxae Caulis(SC)is the vine stem of Sargentodoxa Cuneata(Oliv.)Rehd.&*** in ***,and it in traditional Chinese medicine has been known for promoting blood circulation and removing blood stasis as recorded in the ancient book“Illustrated Classics of Materia Medica”.It has been used effectively to treat blood stasis too in modern clinical ***,the anti-hyperlipidemia effect of SC is not fully *** paper aims at exploring the use of SC stems to improve the balance of blood lipids in the body,and its new role in treating ***:The effects of SC extract on hyperlipidemia were explored by combining lipidomics and gut ***,we explored the potential mechanism of SC in treating hyperlipidemia by pathway ***:The results showed that the stem extract of SC could restore the physiological and biochemical indices of hyperlipidemia in mice,as well as repair the morphological and structural damage to *** to the Model group,the SC extract significantly reduced the liver index,epididymal fat index,and Lee’s *** also significantly decreased serum levels of total cholesterol,triglycerides,low-density lipoprotein cholesterol,peroxisome proliferator-activated receptor gamma(PPAR-γ),D-lactate,and free fatty acids,while significantly increasing the relative content of peroxisome proliferator-activated receptor alpha(PPAR-α).These changes were statistically ***-targeted lipidomics,based on LC-MS,were utilized to investigate the lipid metabolism characteristics in serum,liver,and epididymal fat of the *** was observed that,compared to the blank group,the Model group exhibited significant changes primarily in glycerol lipids and *** treatment group also displayed alterations in these lipids.A total of 38,81,and 27 differential lipids were identified in serum,liver,and epididymal fat samples,*** these,14 common differenti

关键词： hyperlipidemia Sargentodoxae Caulis lipidomics intestinal flora

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Predictive models on photolysis and photoinduced toxicity o persistent organic chemicals

引用

Frontiers of Environmental Science & Engineering 2013年第6期7卷 803-814页

作者： qing zhang National Natural Science Foundation of China Beijing 100085 China

Photodegradation is a major abiotic transfor- mation pathway of toxic chemicals in the environment, which in some cases might lead to photoinduced toxicities. The data on photodegradation kinetics and photoinduced toxicities of organic chemicals are essential for their risk assessment. However, the relevant data are only available for a limited number of chemicals, due to the difficulty and high cost of experimental determination. Quantitative structure-activity relationship （QSAR） models that relate photodegradation kinetics or photoinduced toxicity of organic chemicals with their physicochemical properties or molecular structural descriptors may enable simple and fast estimation of their photochemical behaviors. This paper reviews the QSAR models on photodegradation quantum yields and rate constants for toxic organic chemicals in different media including liquid phase, gaseous phase, surfaces of plant leaves, and QSAR models on photo- induced toxicity of organic chemicals to plants, bacteria, and aquatic invertebrates. Further prospects for QSAR model development on photodegradation kinetics and photoinduced toxicity of refractory organic chemicals are proposed.

关键词： quantitative structure-activity relationship(QSAR) models photodegradation persistent organicpollutants environmental media mechanisms

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Valuation of Stock Loans Under a Markov Chain Model

引用

Journal of Systems Science & Complexity 2016年第1期29卷 171-186页

作者： PRAGER David zhang qing Department of Mathematics Anderson University Department of Mathematics The University of Georgia

In recent years the use of Markov chain models to model stock price movement has received increased attention among *** chain models combine the discrete movements of a binomial tree model while retaining the Markovian properties of Brownian motion,thus allowing the best properties of both of these *** this paper,the authors consider a Markov chain model in which the underlying market is solely determined by a two-state Markov *** a Markov chain model is strikingly simple and yet appears capable of capturing various market *** proper selection of parameters,the Markov chain model can produce sample paths that are very similar *** very distinct from a classical Brownian motion,as the authors demonstrate in this *** paper studies the stock loan valuation,or the value of a loan in which a risky share of stock is used as collateral,under such a *** programming equations in terms of variational inequalities are used to capture the dynamics of the *** equations are solved in *** optimal solutions are *** examples are also reported to illustrate the results.

关键词： Closed-form solution Markov chain model stock loan

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Learning topological defects formation with neural networks in a quantum phase transition

引用

Communications in Theoretical Physics 2024年第5期76卷 68-76页

作者： Han-qing Shi Hai-qing zhang Center for Gravitational Physics Department of Space ScienceBeihang UniversityBeijing 100191China Peng Huanwu Collaborative Center for Research and Education Beihang UniversityBeijing 100191China

Neural networks possess formidable representational power,rendering them invaluable in solving complex quantum many-body *** they excel at analyzing static solutions,nonequilibrium processes,including critical dynamics during a quantum phase transition,pose a greater challenge for neural *** address this,we utilize neural networks and machine learning algorithms to investigate time evolutions,universal statistics,and correlations of topological defects in a one-dimensional transverse-field quantum Ising ***,our analysis involves computing the energy of the system during a quantum phase transition following a linear quench of the transverse magnetic field *** excitation energies satisfy a power-law relation to the quench rate,indicating a proportional relationship between the excitation energy and the kink ***,we establish a universal power-law relationship between the first three cumulants of the kink numbers and the quench rate,indicating a binomial distribution of the ***,the normalized kink-kink correlations are also investigated and it is found that the numerical values are consistent with the analytic formula.

关键词： neural networks machine learning transverse-field quantum Ising model kibble-zurek mechanism

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Relationship　between　global　seismicity　and　solar　activities

引用

Acta Seismologica Sinica(English Edition) 1998年第4期11卷 495-500页

作者： Gui-qing zhang Beijing Astronomical Observatory Chinese Academy of Science Beijing China

ＲｅｌａｔｉｏｎｓｈｉｐｂｅｔｗｅｅｎｇｌｏｂａｌｓｅｉｓｍｉｃｉｔｙａｎｄｓｏｌａｒａｃｔｉｖｉｔｉｅｓＧＵＩ－ＱＩＮＧＺＨＡＮＧ（张桂清）ＢｅｉｊｉｎｇＡｓｔｒｏｎｏｍｉｃａｌＯｂｓｅｒｖａｔｏｒｙ，Ｃｈｉｎｅｓ... 详细信息

ＲｅｌａｔｉｏｎｓｈｉｐｂｅｔｗｅｅｎｇｌｏｂａｌｓｅｉｓｍｉｃｉｔｙａｎｄｓｏｌａｒａｃｔｉｖｉｔｉｅｓＧＵＩ－ＱＩＮＧＺＨＡＮＧ（张桂清）ＢｅｉｊｉｎｇＡｓｔｒｏｎｏｍｉｃａｌＯｂｓｅｒｖａｔｏｒｙ，ＣｈｉｎｅｓｅＡｃａｄｅｍｙｏｆＳｃｉｅｎｃｅ...

关键词： Solar activity Solar proton events Solar radio flux Sunspot numbers

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Phase relations and hydrogenation behavior of (La_(1-x)Mg_x)_3Al alloys

引用

Rare Metals 2007年第1期26卷 8-12页

作者： LIU Yujie zhang qing＇an School of Materials Science and Engineering Anhui University of Technology Ma＇anshan 243002 China

The crystal structures and hydrogenation behavior of （La1-xMgx）3Al （x = 0.1, 0.2, 0.3, and 0.4） alloys were investigated. It was found that the alloys with x = 0.1 and 0.2 consist of La（Mg,Al）, La, and a novel phase. The novel phase was determined as La2Al. It is shown that the amount of La2Al decreases as the Mg content increases. When x increases to 0.3, only La（Mg,Al） and a small amount of La2Al exist. When x is 0.4, La2Al phase disappears and the alloy contains both La（Mg,Al） and La（Al,Mg）2 Laves phase. The （Lao.9MgoA）3Al and （***0.3）3Al alloys can be decomposed into LaH3, MgH2, and La2Al5 by the absorption of hydrogen at 473 K.

关键词： intermetallic compound crystal structure X-ray diffraction hydrogenation characteristic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of Al content on the phase structure and the hydrogenation characteristic of La(Mg_(1-x)Al_x) alloys

引用

Rare Metals 2006年第6期25卷 654-658页

作者： HOU qingyu zhang qing＇an School of Materials Science and Engineering Anhui University of Technology Ma＇anshan 243002 China

La（Mg1-xAlx）（x=0.2, 0.4, 0.6, 0.8） alloys have been prepared using induction melting followed by annealing. It is found that partial substitution of Mg by Al does not lead to a change in crystal structure, and the alloys have a single LaMg phase when x 〈 0.4. The lattice parameter of the LaMg phase decreases obviously after the partial substitution of Mg by Al. However, further substitution of Mg by Al leads to the coexistence of multiple phases when x ≥ 0.6. The alloys consist of the LaMg, LaAl, LaAl2, and La5Al4 phases. The LaMg phase decreases, whereas the La5Al4 phase increases with the increase in x. The Al-substituted La（Mgo.6Al0.4） alloy can be hydrogenated into the tetragonal LaH3, cubic LaH3, MgH2, and LaPd under 5 MPa at 473 K for 5 d.

关键词： intermetallic compound phase structure hydrogenation characteristic X-ray diffraction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Vertical Diffusion Coefficient with Stratification Effect for Silty Sediment Suspension Under Waves

引用

China Ocean Engineering 2023年第2期37卷 323-332页

作者： YANG Guang-yao zhang qing-he State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin UniversityTianjin 300072China

To analyze previous experimental data of suspended sediment concentration for silty sediment with different sediment particle sizes due to waves, a new stratification correction coefficient is presented. The suspended sediment concentration gradient and sediment particle diameter are selected as parameters. Furthermore, a diffusion coefficient model with a stratification effect over the whole water depth for silty sediment suspension under waves is developed. The comparison between the suspended sediment concentration calculated by the presented model and several groups of experimental data shows that the model can reasonably reflect the vertical distribution of silty sediment *** stratification effect calculated by the present model decreases with an increase in the sediment particle diameter,which indicates that the model can be extended to describe the suspended sediment concentration of fine to medium sand when the near-bottom sediment concentration is not very high. Although the original model needs to be iteratively solved, the approximate method without iteration is recommended for applications when the near bottom sediment concentration is between 10 and 20 kg/m~3 due to the small difference between the non-iterative and iterative solution for near bed layer suspended sediment concentration, which plays a major role in sediment transport.

关键词： stratification silty sediment suspension diffusion coefficient wave

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A macro-meso constitutive law for concrete having imperfect interface and nonlinear matrix

引用

Science China(Technological Sciences) 2009年第3期52卷 634-640页

作者： qing zhang XiaoZhou Xia Department of Engineering Mechanics Hohai University Nanjing 210098 China Institute of Construct Guangdong University of Technology Guangzhou 510006 China

The overall behavior of concrete depends on its meso structures such as aggregate shape, interface status, and mortar matrix property. The two key meso structure characters of concrete, bond status of interface and nonlinear property of matrix, are considered in focus. The variational structure principle is adopted to establish the macro-meso constitutive law of concrete. Specially, a linear reference composite material is selected to make its effective behavior approach the nonlinear overall behavior of concrete. And the overall property of linear reference composite can be estimated by classical estimation method such as self-consistent estimates method and Mori-Tanaka method. This variational structure method involves an optimum problem ultimately. Finally, the macro-meso constitutive law of concrete is established by optimizing the shear modulus of matrix of the linear reference composite. By analyzing the constitutive relation of concrete established, we find that the brittleness of concrete stems from the imperfect interface and the shear dilation property of concrete comes from the micro holes contained in concrete.

关键词： imperfect interface matrix nonlinear property variational structure principle macro-meso constitutive law concrete

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A destructive field study on the behavior of piles under tension and compression

引用

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第4期12卷 291-300页

作者： Zhong-miao zhang Qian-qing zhang Feng YU MOE Key Laboratory of Soft Soils and Geoenvironmental Engineering Zhejiang University Hangzhou 310058 China Institute of Geotechnieal Engineering Zhejiang University Hangzhou 310058 China School of Civil Engineering and Architecture Zhejiang Sci-Tech University Hangzhou 310018 China

This paper involves a series of destructive full-scale load tests on long bored piles instrumented with strain gauges along the shafts,including two compression and two tension loading *** load-displacement response,axial force,skin friction,and the thresholds of the slip displacement for fully mobilizing the skin resistances in different soils are ***,the theoretical solution for estimating the pile tip settlement under compression was adopted to analyze the test *** was found that the measured skin frictions for the piles under compression were about 6% to 42% higher than the estimated values of the cone penetration tests(CPTs),whereas the measured skin frictions in the uplift cases were about 16% to 50% smaller than the estimated *** addition,the average limited skin frictions for the tension piles were about 0.36 to 0.78 times the average ultimate skin frictions for the piles under *** also can be indicated that the skin friction along the pile depth approached the limited state,and decreased from a peak value with increasing loads.

关键词： Destructive full-scale test Load-displacement response Axial force Pile-soil relative displacement Skin friction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：