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优质护理在妊娠期糖尿病护理中的应用

糖尿病新世界 2022年第6期25卷 118-121页

作者：兰晴曹县人民医院传染科山东菏泽274400

目的分析优质护理在妊娠期糖尿病护理当中的应用效果。方法选取2019年1月—2020年12月该院收治的96例妊娠期糖尿病患者作为研究对象,然后按照入院单双号时间将患者划分为观察组和对照组,每组48例。两组患者全部应用常规护理模式,观察组... 详细信息

目的分析优质护理在妊娠期糖尿病护理当中的应用效果。方法选取2019年1月—2020年12月该院收治的96例妊娠期糖尿病患者作为研究对象,然后按照入院单双号时间将患者划分为观察组和对照组,每组48例。两组患者全部应用常规护理模式,观察组患者在此基础上接受优质护理干预。在护理结束后比较两组患者的血糖控制情况、健康知识掌握状况以及新生儿结局。结果观察组患者空腹血糖值为(7.3±0.3)mmol/L、餐后2 h血糖为(10.4±0.8)mmol/L,优于对照组,差异有统计学意义(P<0.05);护理后,观察组健康教育评分(74.0±1.9)分,明显高于对照组健康教育评分(52.2±2.4)分,差异有统计学意义(P<0.05);在妊娠结局方面,观察组的新生儿并发症发生率为4.2%,低于对照组的新生儿并发症发生率16.6%,差异有统计学意义(P<0.05)。结论优质护理能够帮助妊娠期糖尿病患者稳定血糖,提升知识水平和自我保健能力,优化妊娠结局,因此具有重要的临床推广价值。

关键词：优质护理妊娠期糖尿病空腹血糖餐后2 h血糖健康教育不良妊娠结局

Long-term postoperative outcomes of bilateral lateral rectus recession vs unilateral recession-resection for intermittent exotropia

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International Journal of Ophthalmology(English edition) 2014年第6期7卷 1043-1047页

作者： Xian Yang Teng-Teng Man Qiao-Xia Tian Gui-Qiu Zhao qing-lan Kong Yan Meng Yan Gao Mei-Zhen Ning Department of Ophthalmology Qingdao University Medical College Department of Ophthalmology the Affiliated Hospital of Medical College Qingdao University Department of Ophthalmology the Ninth People's Hospital of Qingdao

AIM: To discuss the long-term postoperative results of bilateral lateral rectus recession(BLR) and unilateral lateral rectus recession-medial rectus resection(RR) in therapy of intermittent ***: We retrospectively analyzed 213 cases of intermittent exotropia who underwent surgery between2008 and 2010. The patients were grouped into BLR group and RR group. Motor outcomes were divided into three groups on the basis of the angle of deviation after surgery: overcorrection(esotropia/phoria >5△), orthophoria(esotropia/phoria ≤5△to exotropia/phoria ≤10△), and undercorrection/recurrence(exotropia/phoria >10△).Titmus test was used to evaluate stereoacuity, the stereoacuity 0.05) between ***, the motor outcomes at 6, 36 mo were signally different in each group, indicating the success rate in RR group at 6mo was higher than that in BLR group(83.02%vs 82.24%, P <0.05) but the result was contrary at the 3y examination(60.75% vs 43.40%, P <0.05). No statistical significance were found in the sensory outcomes between the groups at mean of 3.7y ***: The motor outcomes in RR group were better than in BLR group at 6mo after surgery, while the3 y outcomes were better in BLR group. This may be due to the recurrence rate of the BLR was lower than the RR group’s.

关键词： intermittent exotropia operation treatment effect

环保目标治理如何促进污染减排?——基于中国首次约束性减排目标计划的分析

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中国地质大学学报（社会科学版） 2022年第2期22卷 75-98页

作者：谌仁俊陈彦龙肖庆兰华中师范大学经济与工商管理学院湖北武汉430079 华中师范大学低碳经济与环境政策研究中心湖北武汉430079 中国人民大学经济学院北京100872 浙江大学经济学院浙江杭州310013

以五年规划为代表的目标治理是中国推动经济转型的制度创新,在生态环境保护方面发挥着具有中国特色的减排效果。以"十一五"期间首次约束性减排目标计划为例,基于双重差分模型,分别从源头治理与末端治理、环保投资与环保监管两大维度分... 详细信息

以五年规划为代表的目标治理是中国推动经济转型的制度创新,在生态环境保护方面发挥着具有中国特色的减排效果。以"十一五"期间首次约束性减排目标计划为例,基于双重差分模型,分别从源头治理与末端治理、环保投资与环保监管两大维度分析环保目标治理如何促进污染减排,识别这种目标治理下中国式减排的特征与源泉。研究发现:从减排特征来看,在"十一五"规划约束性减排目标计划下,SO_(2)减排以末端治理为主,一旦对地方施以更大的减排"加码压力",不仅能实现向源头治理主导的转变,而且减排效果会大大提高。究其动力源泉,提高环保投资的治理效率是实现SO_(2)减排的最大动力,环保监管的约束力只有在地方承受较大的"加码压力"时才会存在,这也是推动减排向源头治理转变的重要方式。此外,本文还发现中央"加码压力"对地方经济带来了负面影响,但会在污染减排上表现出空间溢出效应。对SO_(2)排放的环保目标治理还会使工业烟(粉)尘产生以末端治理为主的协同减排。本文认为要想使环保目标治理产生更大减排效果,需要合理运用环保目标治理体系,进一步加强源头治理,继续提高环保投资的治理效率,激活环保监管约束,形成减排投资驱动与监管约束的双动能。

关键词： “十一五”污染物排放总量控制污染减排环境治理环保投资

Leaf Morphology Genes SRL1 and RENL1 Co-Regulate Cellulose Synthesis and Affect Rice Drought Tolerance

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Rice science 2024年第1期31卷 103-117,I0020-I0022页

作者： LIU Dan ZHAO Huibo WANG Zi’an XU Jing LIU Yiting WANG Jiajia CHEN Minmin LIU Xiong ZHANG Zhihai CEN Jiangsu ZHU Li HU Jiang REN Deyong GAO Zhenyu DONG Guojun ZHANG Qiang SHEN lan LI qing QIAN Qian HU Songping ZHANG Guangheng State Key Laboratory of Rice Biology and Breeding China National Rice Research InstituteHangzhou 310006China Research Center of Plant Functional Genes and Tissue Culture Technology College of Bioscience and BioengineeringJiangxi Agricultural UniversityNanchang 330045China Qian Qian Academician Workstation National Nanfan Research Institute(Sanya)Chinese Academy of Agricultural SciencesSanya 572024China

The morphological development of rice(Oryza sativa L.)leaves is closely related to plant architecture,physiological activities,and ***,it is unclear whether there is a co-regulatory relationship between the morphological development of leaves and adaptation to drought *** this study,a drought-sensitive,roll-enhanced,and narrow-leaf mutant(renl1)was induced from a semi-rolled leaf mutant(srl1)by ethyl methane sulfonate(EMS),which was obtained from Nipponbare(NPB)through ***-based cloning and functional validation showed that RENL1 encodes a cellulose synthase,allelic to NRL1/*** RENL1 mutation resulted in reduced vascular bundles,vesicular cells,cellulose,and hemicellulose contents in cell walls,diminishing the water-holding capacity of *** addition,the root system of the renl1 mutant was poorly developed and its ability to scavenge reactive oxygen species(ROS)was decreased,leading to an increase in ROS after drought ***,genetic results showed that RENL1 and SRL1 synergistically regulated cell wall *** results revealed a theoretical basis for further elucidating the molecular regulation mechanism of cellulose on rice drought tolerance,and provided a new genetic resource for enhancing the synergistic regulation network of plant type and stress resistance,thereby realizing simultaneous improvement of multiple traits in rice.

关键词： cellulose cell wall drought tolerance leaf morphology rice

Gastrodin Derivatives from Gastrodia elata

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Natural Products and Bioprospecting 2019年第6期9卷 393-404页

作者： Cheng-Bo Xu qing-lan Guo Ya-Nan Wang Sheng Lin Cheng-Gen Zhu Jian-Gong Shi State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100050People’s Republic of China

Nine new gastrodin derivatives,including seven p-hydroxybenzyl-modified gastrodin ethers(1-7),6′-O-acetylgastrodin(8),and 4-[α-d-glucopyranosyl-(1→6)-β-d-glucopyranosyloxy]benzyl alcohol(9),together with seven known derivatives,were isolated from an aqueous extract of Gastrodia elata(“tian ma”)*** structures were determined by spectroscopic and chemical methods as well as single crystal X-ray *** 1-4,7,10,and 11 were also isolated from a reaction mixture by refluxing gastrodin and p-hydroxybenzyl alcohol in *** both gastrodin and p-hydroxybenzyl alcohol exist in the plant,the reaction results provide evidence for the production and increase/decrease of potential effective/toxic components when“tian ma”is decocted solely or together with ingredients in Chinese traditional medicine formulations,though the isolates were inactive in the preliminarily cell-based assays at concentrations of 10μ***,using ultra-performance liquid chromatography high-resolution electrospray ionization mass spectrometry(UPLC-HRESIMS),4,7,10,and 11,as well as component variations,were detectable in the freshly prepared extracts of different types of samples,including the freeze-dried fresh *** rhizomes.

关键词： Orchidaceae Gastrodia elata Blume p-Hydroxybenzyl gastrodin ethers Reaction of gastrodin with p-hydroxybenzyl alcohol Component variation during decocting

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合作数字参考咨询服务研究

情报科学 2007年第7期25卷 1022-1029页

作者：蓝青广东省立中山图书馆广东广州510110

本文阐述了开展合作数字参考咨询服务的动因及理念,通过联合参考咨询网的系统功能及使用情况分析,探讨了合作数字参考咨询发展的制约因素与对策。

关键词：合作数字参考咨询系统功能信息服务特约因素对策

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新见仇昌祚《西游记序》考论

北京社会科学 2019年第10期 60-66页

作者：蓝青中山大学中文系

广东省立中山图书馆藏有孤本文献仇昌祚《漪园集》一部,其中有《西游记序》一篇,为诸多《西游记》资料汇编著作所不载,亦未见其他论著征引。该文约作于清康熙间,所序者为闽斋堂刻本,序文部分明显延续了明代以心学释《西游记》的传统,将... 详细信息

广东省立中山图书馆藏有孤本文献仇昌祚《漪园集》一部,其中有《西游记序》一篇,为诸多《西游记》资料汇编著作所不载,亦未见其他论著征引。该文约作于清康熙间,所序者为闽斋堂刻本,序文部分明显延续了明代以心学释《西游记》的传统,将取经故事视为由放心到收心、由作魔到灭魔的过程,而窾言部分则体现出偏向原儒的倾向。该序对《西游记》的审美特征亦颇有见解,还对闽斋堂本《西游记》的传播研究有着重要意义,值得学界重视。

关键词：仇昌祚《西游记序》心学

MicroRNA Profiling of Transgenic Mice with Myocardial Overexpression of Nucleolin

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Chinese Medical Journal 2018年第3期131卷 339-346页

作者： qing-lan Lyu Bi-Mei Jiang Bin Zhou Li Sun Zhong-Yi Tong Yuan-Bin Li Yu-Ting Tang Hui Sun Mei-Dong Liu Xian-Zhong Xiao Department of Pathophysiology Xiangya School of Basic Medical Sciences Central South University Changsha Hunan 410078 China Department of Rheumatology Xiangya Hospital Central South University Changsha Hunan 410008 China Department of Pathology The Second Xiangya Hospital Central South University Changsha Hunan 410000 China

Background：Nucleolin （NCL） is the most abundant RNA-binding protein in the cell nucleolus and plays an important role in chromatin stability,ribosome assembly,ribosomal RNA maturation,ribosomal DNA transcription,nucleocytoplasmic transport,and regulation of RNA stability and translation *** addition to its anti-apoptotic properties,the underlying mechanisms associated with NCL-related roles in different cellular processes remain *** this study,the effect of NCL on microRNA （miRNA） expression was evaluated by generating transgenic mice with myocardial overexpression of NCL and by analyzing microarrays of mature and precursor miRNAs from ***：Using microinjection ofalpha-MyHc clone 26-NCL plasmids,we generated transgenic mice with myocardial overexpression of NCL firstly,and then mature and precursor miRNAs expression profiles were analyzed in NCL transgenic mice （n =3） and wild-type （WT） mice （n =3） by miRNA *** Package for the Social Sciences version 16.0 software （SPSS,Inc.,Chicago,IL,USA） was used to perform Student＇s t-test,and statistical significance was determined at P 〈 ***：Several miRNAs were found to be differentially expressed,of which 11 were upregulated and 4 were downregulated in transgenic mice with myocardial overexpression of NCL compared to those in WT *** differentially expressed miRNAs were subsequently confirmed and quantified by real-time quantitative reverse transcription-polymerase chain *** analysis was used for the prediction of miRNA ***,in vitro experiments showed that NCL regulated miR-21 expression following hydrogen peroxide ***：Myocardial-protection mechanisms exerted by NCL might be mediated by the miRNAs identified in this study.

关键词： MicroRNA microarray Myocardium Nucleolin Transgenic mice

基于多源数据的城市活力区域识别及驱动因素评估——以上海市为例

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科学技术与工程 2022年第3期22卷 1173-1182页

作者：邱兰清余萍马慧鑫天津农学院水利工程学院天津300392

活力是评价城市空间品质的重要指标,也是城市空间品质提升的目标之一。城市是一个复杂的巨系统,城市的活力也因此受到多元、复杂的各种因素的影响。聚焦于街道/乡镇这一基本行政空间单元,运用ESDA(exploratory spatial data analysis)方... 详细信息

活力是评价城市空间品质的重要指标,也是城市空间品质提升的目标之一。城市是一个复杂的巨系统,城市的活力也因此受到多元、复杂的各种因素的影响。聚焦于街道/乡镇这一基本行政空间单元,运用ESDA(exploratory spatial data analysis)方法,结合信息熵模型,对上海市城市活力区域进行了识别评估,对其驱动因素进行了分析,并可用于对未来结果的预测。研究发现城市活力受到功能混合度、常住人口分布、交通可达性、公共交通服务水平、设施供给密度的显著影响,并基于以上研究结果试提出了相应的规划设计建议。

关键词：活力功能混合度 POIs 空间自相关地理加权回归