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西藏昂仁县树龄超过300年和1000年的古树树木年轮学论证

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西藏科技 2024年第7期46卷 14-18,39页

作者：旦增欧珠喻武郑嘉诚张齐兵西藏农牧学院资源与环境学院林芝860000 中国科学院植物研究所北京100093

西藏西部地区由于生境严酷,很难发现树龄特大的古树。笔者在2023年对昂仁县的古树资源调查中,发现了两棵树龄特大的大果圆柏(Juiperus tibetica Kom.)古树。一棵古树位于达局乡甘丹塔空寺内,采集到的树芯样本接近树干髓心,通过树木年轮... 详细信息

西藏西部地区由于生境严酷,很难发现树龄特大的古树。笔者在2023年对昂仁县的古树资源调查中,发现了两棵树龄特大的大果圆柏(Juiperus tibetica Kom.)古树。一棵古树位于达局乡甘丹塔空寺内,采集到的树芯样本接近树干髓心,通过树木年轮学方法鉴定其树龄约为306年(起始于1716年)。另一棵古树位于多白乡谢村,其胸围高达8.5米,仅采集到12厘米的树芯样本上有216个年轮,推算这棵古树的树龄超过了千年。两株古树的树木年轮数据既反映了区域气候变化信号,也反映了局地小生境和人们对古树的保护信号,同时显示了古树目前生长处于健康状态。研究结果丰富了昂仁县古树本底资源信息,对认识西藏西部地区古树文化、生态、气候、科研和社会价值具有重要意义。

关键词：古树资源千年古树古树生长历史大果圆柏

抗生素使用时间与预防肝切除术后手术部位感染效果的相关性分析

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中华普通外科杂志 2024年第7期39卷 534-538页

作者：白振华施祥德唐启彬余先焕张锐刘超中山大学孙逸仙纪念医院胆胰外科广州510288

目的分析抗生素预防肝切除术后手术部位感染(surgical site infection,SSI)的有效性。方法回顾性分析2019年1月至2021年12月于中山大学孙逸仙纪念医院施行肝切除术患者的临床资料。结果共509例患者纳入研究。不同预防治疗时间组的SSI发... 详细信息

目的分析抗生素预防肝切除术后手术部位感染(surgical site infection,SSI)的有效性。方法回顾性分析2019年1月至2021年12月于中山大学孙逸仙纪念医院施行肝切除术患者的临床资料。结果共509例患者纳入研究。不同预防治疗时间组的SSI发生率差异无统计学意义(P>0.05)。单因素分析结果显示胆漏、肝切除范围、手术方式、麻醉分级和手术时间为影响肝切除术后SSI的可能危险因素(P300 min可能是影响肝切除术后SSI的独立危险因素(P<0.05)。结论肝切除术后延长抗生素使用时间以预防手术部位的感染可能是不必要的。

关键词：肝切除术手术部位感染抗生素危险因素

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基于前光模组的反射式液晶显示视角

液晶与显示 2024年第1期39卷 25-31页

作者：李可敬李香君俞良许启民吕国强王梓冯奇斌合肥工业大学仪器科学与光电工程学院安徽合肥230009 芜湖长信科技有限公司安徽芜湖241007 合肥工业大学光电技术研究院安徽合肥230009

反射式液晶显示具有功耗低、绿色环保的优点。但由于没有增亮膜等光学膜系对视角进行调控,常见的网点形貌下视角曲线存在跳变、不均匀等问题。为了改善反射式液晶显示的视角问题,本文建立了反射式液晶模组仿真模型进行探究。首先,分析... 详细信息

反射式液晶显示具有功耗低、绿色环保的优点。但由于没有增亮膜等光学膜系对视角进行调控,常见的网点形貌下视角曲线存在跳变、不均匀等问题。为了改善反射式液晶显示的视角问题,本文建立了反射式液晶模组仿真模型进行探究。首先,分析了前光模组存在的视角问题。接着,以圆锥形和圆台形网点为例分析了网点形貌对视角的影响,并提出棱柱形网点以改善视角。仿真结果表明,棱柱形网点可以有效解决垂直于入射光方向±35°视角的曲线跳变及不均匀问题,且将视角中心亮度相比于圆锥形网点提升了52.3%。本研究对反射式液晶显示设备的视角设计具有重要参考意义。

关键词：前光模组网点形貌导光板视角

PD-1信号通路在硫酸脑苷脂介导的抗哮喘气道炎症中的作用

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武汉大学学报（医学版） 2024年第1期45卷 1-7页

作者：倪海阳钟洁莹甘劭丁林琪斌黄毅丁续红余红缨聂汉祥武汉大学人民医院呼吸与危重症医学科湖北武汉430060

目的:观察程序性死亡受体1(PD-1)信号通路在硫酸脑苷脂介导的抗哮喘气道炎症的作用。方法:WTBALB/c小鼠随机分入正常对照组、哮喘对照组、硫酸脑苷脂治疗哮喘组、抗PD-1 mAb治疗哮喘组和硫酸脑苷脂+抗PD-1 mAb治疗哮喘组,每组5只。四组... 详细信息

目的:观察程序性死亡受体1(PD-1)信号通路在硫酸脑苷脂介导的抗哮喘气道炎症的作用。方法:WTBALB/c小鼠随机分入正常对照组、哮喘对照组、硫酸脑苷脂治疗哮喘组、抗PD-1 mAb治疗哮喘组和硫酸脑苷脂+抗PD-1 mAb治疗哮喘组,每组5只。四组哮喘小鼠采用鸡卵清蛋白(OVA)和PBS致敏和激发,其余各组在相应时间用等量PBS替代;硫酸脑苷脂治疗哮喘组和硫酸脑苷脂+抗PD-1 mAb治疗哮喘组在激发前1 h腹腔注射硫酸脑苷(20μg/只),其余各组在相应时间用等量PBS替代;抗PD-1 mAb治疗哮喘组和硫酸脑苷脂+抗PD-1mAb治疗哮喘组于硫酸脑苷脂干预前24 h腹腔注射抗PD-1单克隆抗体(500μg/只),其余各组在相应时间用等量PBS替代。采用流式细胞术检测肺PD-1+T细胞数量;HE和PAS染色检测肺组织学和支气管杯状细胞数量;瑞氏-姬姆萨染色检测支气管肺泡灌洗液(BALF)细胞总数和分类计数;ELISA法检测血清OVA特异性IgE和BALF中IL-4、IL-5和IL-13水平。结果:抗PD-1 mAb治疗哮喘组小鼠肺组织炎症细胞浸润增加;气道基底膜杯状细胞数量以及BALF中细胞总数和嗜酸粒细胞数量、血清OVA特异性IgE和BALF中IL-4、IL-5和IL-13水平均明显高于哮喘对照组(均P<0.01)。硫酸脑苷脂+抗PD-1 mAb治疗哮喘组小鼠肺组织炎症细胞浸润增高;气道基底膜杯状细胞数量以及BALF中细胞总数和嗜酸粒细胞数、血清OVA特异性IgE和BALF中IL-4、IL-5和IL-13水平明显高于硫酸脑苷脂治疗哮喘组(P<0.01或P<0.05)。硫酸脑苷脂治疗哮喘组小鼠肺PD-1+T细胞数量明显高于哮喘对照组和正常对照组(均P<0.01)。结论:硫酸脑苷脂可能通过激活PD-1信号通路抑制哮喘小鼠气道炎症。

关键词：哮喘气道炎症硫酸脑苷脂程序性死亡受体1

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多连通域浮式平台波浪载荷水池模型试验研究

海洋工程 2024年第1期42卷 58-66页

作者：耿彦超丁军俞俊王琦彬凌宏杰邬志佳朱云龙谢卓雨中国船舶科学研究中心江苏无锡214082 深海技术科学太湖实验室江苏无锡214082 江苏科技大学江苏镇江212003

大型多连通域浮式平台的典型代表是大型海上旅游浮式综合体,依据概念设计,开展大型多连通域浮式平台的波浪载荷水池模型试验研究,试验对不同海况下4种典型多连通域浮式平台方案进行波浪载荷测量,包括剖面的垂向弯矩、水平弯矩和扭矩等,... 详细信息

大型多连通域浮式平台的典型代表是大型海上旅游浮式综合体,依据概念设计,开展大型多连通域浮式平台的波浪载荷水池模型试验研究,试验对不同海况下4种典型多连通域浮式平台方案进行波浪载荷测量,包括剖面的垂向弯矩、水平弯矩和扭矩等,通过观察试验现象和分析测量数据,获得了不同方案大型多连通域浮式平台的波浪载荷特性。试验结果表明:由于平台质量大、振动阻尼大,所以高频载荷成分小;平台在自由状态下载荷值基本都小于平台只释放垂荡状态载荷值;在方案四高波高状态下,平台波浪载荷的高频成分包含了波浪的非线性、约束柱与平台之间的耦合、平台自身的高频振动等。研究成果可为大型海上旅游浮式综合体的结构设计提供设计载荷输入,支撑平台的强度校核评估。

关键词：多连通域浮体海洋平台波浪载荷水弹性响应

Effect of textural property of coconut shell-based activated carbon on desorption activation energy of benzothiophene

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Frontiers of Chemical Science and Engineering 2008年第3期2卷 269-275页

作者： Moxin yu Zhong LI Hongxia XI qibin XIA Shuwen WANG College of Chemical and Energy Engineering South China University of TechnologyThe Key Laboratory of Enhanced Heat Transfer and Energy ConversationMinistry of EducationGuangzhou 510640China

In this work,the effect of the textural property of activated carbons on desorption activation energy and adsorption capacity for benzothiophene(BT)was *** surface areas and the textural parameters of three kinds of the activated carbons,namely SY-6,SY-13 and SY-19,were measured with an ASAP 2010 *** desorption activation energies of BT on the activated carbons were determined by temperature-programmed desorption(TPD).Static adsorption experiments were carried out to determine the isotherms of BT on the activated *** influence of the textural property of the activated carbons on desorption activation energy and the adsorption capacity for BT was *** showed that the BET surface areas of the activated carbons,SY-6,SY-13 and SY-19 were 1106,1070 and 689 m2·g^(-1),respectively,and their average pore diameters were 1.96,2.58 and 2.16 nm,*** TPD results indicated that the desorption activation energy of BT on the activated carbons,SY-6,SY-19 and SY-13 were 58.84,53.02 and 42.57 KJ/mol,*** isotherms showed that the amount of BT adsorbed on the activated carbons followed the order of SY-6>SY-19>*** smaller the average pore diameter of the activated carbon,the stronger its adsorption for BT and the higher the activation energy required for BT desorption on its *** Freundlich adsorption isotherm model can be properly used to formulate the adsorption behavior of BT on the activated carbons.

关键词： activated carbon benzothiophene desorption activation energy average pore diameter adsorption equilibrium

抗CD20单克隆抗体对哮喘小鼠气道炎症的影响

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武汉大学学报（医学版） 2024年第6期45卷 651-656页

作者：贺基龙章宗悦左小淑林琪斌倪海阳丁续红黄毅余红缨聂汉祥武汉大学人民医院呼吸与危重症医学科湖北武汉430060

目的:观察抗CD20单克隆抗体(简称抗CD20单抗)对哮喘小鼠气道炎症的影响。方法:将15只6~8周龄的BALB/c雌性小鼠随机分成正常对照组、哮喘对照组和抗CD20单抗治疗组,每组5只。哮喘对照组和抗CD20单抗治疗组以屋尘螨(HDM)致敏和激发,正常... 详细信息

目的:观察抗CD20单克隆抗体(简称抗CD20单抗)对哮喘小鼠气道炎症的影响。方法:将15只6~8周龄的BALB/c雌性小鼠随机分成正常对照组、哮喘对照组和抗CD20单抗治疗组,每组5只。哮喘对照组和抗CD20单抗治疗组以屋尘螨(HDM)致敏和激发,正常对照组以等量PBS代替,其中抗CD20单抗治疗组在第1次激发前2 d给予抗CD20单抗经鼻滴入联合腹腔注射,正常对照组和哮喘对照组给予等量同型对照抗体代替。苏木精-伊红(HE)染色和糖原(PAS)染色观察肺部炎症和气道杯状细胞增生;瑞氏-吉姆萨染色检测支气管肺泡灌洗液(BALF)细胞总数和分类计数;酶联免疫吸附试验检测血清HDM特异性IgE及BALF中IL-4、IL-5、IL-13、IFN-γ和IL-10水平;流式细胞术检测肺CD19+B细胞数量。结果:与哮喘对照组比较,抗CD20单抗治疗组哮喘小鼠肺组织炎性细胞浸润减少,气道基底膜杯状细胞数量以及BALF中细胞总数、嗜酸粒细胞、巨噬细胞和淋巴细胞数量明显减少(P0.05);BALF中IL-10水平明显增高(P<0.01)。同时,抗CD20单抗治疗组哮喘小鼠肺CD19+B细胞数量明显减少(P<0.01)。结论:经鼻滴入联合腹腔注射抗CD20单抗可以减轻哮喘小鼠气道炎症,可能与其去除肺B细胞导致气道IL-10水平增高有关。

关键词：哮喘抗CD20单克隆抗体气道炎症 B细胞白细胞介素-10

Building a Large-Scale and Wide-Area Quantum Internet Based on an OSI-Alike Model

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China Communications 2021年第10期18卷 1-14页

作者： Zhonghui Li Kaiping Xue Jian Li Nenghai yu Jianqing Liu David S.L.Wei qibin Sun Jun Lu School of Cyber Security University of Science and Technology of ChinaHefeiAnhui 230027China School of Information Science and Technology University of Science and Technology of ChinaHefeiAnhui 230027China Department of Electrical and Computer Engineering University of Alabama in HuntsvilleHuntsvilleAL 35899USA Department of Computer and Information Science Fordham UniversityBronxNY 10458USA

The theory and experiment of quantum information have been studied extensively in recent years,and the feasibility of quantum communication has been *** the fundamental technology is not yet mature,research on quantum internet should be *** implement quantum internet,an architecture that describes how quantum nodes are linked to form networks and how protocol functions are vertically composed need to be developed *** this paper,we present a novel design of a clusterbased structure to describe how quantum nodes are interconnected,and how the structure can improve the performance of qubit transmission and reduce the network *** idea of the quantum local area network(QLAN)is proposed as an essential component of the quantum ***,each quantum repeater links to neighboring repeaters to form a core network,and multiple QLANs are connected through the core *** core network can be grouped into different hierarchical quantum repeater networks according to needed service *** the sake of interoperability and fast prototyping,we adopt the idea of OSI layering model of the current Internet in the design of quantum ***,we elaborate on the composition of quantum nodes and the realization of end-to-end communication.

关键词： quantum internet entanglement swapping quantum repeater teleportation

A Localization Method of High Energy Transients for All-sky Gamma-ray Monitor

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Research in Astronomy and Astrophysics 2024年第10期24卷 25-35页

作者： Yi Zhao Wangchen Xue Shaolin Xiong Qi Luo yuanhao Wang Jiacong Liu Heng yu Xiaoyun Zhao yue Huang Jinyuan Liao Jianchao Sun Xiaobo Li qibin Yi Ce Cai Shuo Xiao Shenglun Xie Chao Zheng Yanqiu Zhang Chenwei Wang Wenjun Tan Zhiwei Guo Chaoyang Li Zhenghua An Gang Chen Yanqi Du Min Gao Ke Gong Dongya Guo Jiang He Jianjian He Bing Li Gang Li Xinqiao Li Jing Liang Xiaohua Liang Yaqing Liu Xiang Ma Rui Qiao Liming Song Xinying Song Xilei Sun Jin Wang Ping Wang Xiangyang Wen Hong Wu Yanbing Xu Sheng Yang Dali Zhang Fan Zhang Hongmei Zhang Peng Zhang Shu Zhang Zhen Zhang Shijie Zheng Keke Zhang Xingbo Han Haiyan Wu Hu Tai Hao Geng Gaopeng Lu Wei Xu Fanchao Lyu Hongbo Zhang Fangjun Lu Shuangnan Zhang Department of Astronomy Beijing Normal UniversityBeijing 100875China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China School of Physics and Optoelectronics Xiangtan UniversityXiangtan 411105China College of Physics Hebei Normal UniversityShijiazhuang 050024China Guizhou Provincial Key Laboratory of Radio Astronomy and Data Processing Guizhou Normal UniversityGuiyang 550001China School of Physics and Electronic Science Guizhou Normal UniversityGuiyang 550001China Institute of Astrophysics Central China Normal UniversityWuhan 430079China College of physics Sciences Technology Hebei UniversityBaoding 071002China Physics and Space Science College China West Normal UniversityNanchong 637002China School of Computing and Artificial Intelligence Southwest Jiaotong UniversityChengdu 611756China College of Electronic and information Engineering Tongji UniversityShanghai 201804China Innovation Academy for Microsatellites of Chinese Academy of Sciences Shanghai 201304China National Space Science Center Chinese Academy of SciencesBeijing 100190China School of Earth and Space Sciences University of Science and Technology of ChinaHefei 230026China Electronic Information School Wuhan UniversityWuhan 430072China Key Laboratory of Transportation Meteorology of China Meteorological Administration Nanjing Joint Institute for Atmospheric SciencesNanjing 210000China Key Laboratory of Middle Atmosphere and Global Environment Observation Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China

Fast and reliable localization of high-energy transients is crucial for characterizing the burst properties and guiding the follow-up *** based on the relative counts of different detectors has been widely used for all-sky gamma-ray *** are two major methods for this count distribution localization:χ^(2)minimization method and the Bayesian *** we propose a modified Bayesian method that could take advantage of both the accuracy of the Bayesian method and the simplicity of the χ^(2)*** comprehensive simulations,we find that our Bayesian method with Poisson likelihood is generally more applicable for various bursts than the χ^(2)method,especially for weak *** further proposed a location-spectrum iteration approach based on the Bayesian inference,which could alleviate the problems caused by the spectral difference between the burst and location *** method is very suitable for scenarios with limited computation resources or timesensitive applications,such as in-flight localization software,and low-latency localization for rapidly follow-up observations.

关键词： methods:data analysis methods:analytical (stars:)gamma-ray burst:general