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Chinese Physics B 2021年第10期30卷 711-718页

作者： Zhen-Xia zhang Ruo-Xian Zhou Man Hua Xin-qiao Li Bin-Bin Ni Ju-Tao Yang National Institute of Natural Hazards MEMCBeijing 100085China Department of Space Physics School of Electronic InformationWuhan UniversityWuhan 430072China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China National Key Laboratory of Electromagnetic Environment China Research Institute of Radiowave PropagationQingdao 266107China

During 2018 major geomagnetic storm,relativistic electron enhancements in extremely low L-shell regions(reaching L∼3)have been reported based on observations of ZH-1 and Van Allen probes satellites,and the storm is highly likely to be accelerated by strong whistler-mode waves occurring near very low L-shell regions where the plasmapause was *** is very interesting to observe the intense chorus-accelerated electrons locating in such low L-shells and filling into the slot *** this paper,we further perform numerical simulation by solving the two-dimensional Fokker-Planck equation based on the bounce-averaged diffusion *** results demonstrate the evolution processes of the chorus-driven electron flux and confirm the flux enhancement in low pitch angle ranges(20◦-50◦)after the wave-particle interaction for tens of *** simulation result is consistent with the observation of potential butterfly pitch angle distributions of relativistic electrons from both ZH-1 and Van Allen probes.

关键词： chorus acceleration extremely low L-shell numerical simulation ZH-1 satellite Van Allen probes

Multistage Self-Assembly Strategy: Designed Synthesis of N-doped Mesoporous Carbon with High and Controllable Pyridine N Content for Ultrahigh Surface-Area-Normalized Capacitance

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CCS Chemistry 2021年第2期3卷 870-881页

作者： Liangliang zhang Tao Wang Tu-Nan Gao Hailong Xiong Rui zhang Zhilin Liu Shuyan Song Sheng Dai Zhen-An qiao State Key Laboratory of Inorganic Synthesis and Preparative Chemistry College of ChemistryJilin UniversityChangchunJilin 130012 State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022 Chemical Sciences Division Oak Ridge National LaboratoryOak RidgeTN 37831

Nitrogen doping could improve the performance of carbon materials in electrocatalysis,CO_(2) adsorption,and energy storage.[1]However,the control of the doping type and the amount of nitrogen(N)-doped in carbon materials in a simple and environmentally friendly way remains ***,we report a facile,multistage,self-assembly strategy for the synthesis of two-dimensional N-doped mesoporous carbon(2D NMC)by using graphene oxide(GO)as a structure-directing *** resultant 2D GO@NMCs rendered quantitatively controllable mesopores(8–25 nm).The 2D GO@NMCs rendered quantitatively controllablemesopores(8–25nm),high and controllable N content(up to 19 wt%),and the percentages of pyridine and pyridone/pyrrolic N atoms were as high as 49.9%and 35.3%,*** to these unique characteristics,the fabricated 2D GO@NMCs exhibited an ultrahigh surface-areanormalized capacitance of up to 90.6μF cm−2,which was much higher than the theoretical electrochemical double-layer capacitance of activated carbon(15–25μF cm−2).Moreover,our proposed multistage self-assembly strategy is versatile,and thus,could be extended to the synthesis of one-dimensional(1D)nanotubes@NMC and zero-dimensional(0D)nanospheres@NMC materials.

关键词： multistage self-assembly mesoporous carbon nitrogen-doped carbon high pyridine nitrogen,supercapacitor

Auto-compensation of velocity-height ratio for Chang’E-2 satellite CCD stereo camera

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Science China(Technological Sciences) 2011年第9期54卷 2243-2246页

作者： XUE Bin ZHAO BaoChang YANG JianFeng GAO Weit qiao WeiDong MA XiaoLong zhang Bo LIU JiaHang ZHAO Wei JING Juan Juan Xi' an Institute of Optics and Precision Mechanics of Chinese Academy of Sciences Xi' an 710119 China Key Laboratory of Spectral Imaging Technology Chinese Academy of Sciences Xi'an 710119 China State Key Laboratory of Transient Optics and Photonics Chinese Academy of Sciences Xi'an 710119 China The Institute of Measurement and Communication Beijing 100830 China

The TDI-CCD imaging method using auto-compensation of velocity-height ratio (VHR) was applied to Chang’E-2 satellite CCD stereo *** that influence the image quality of the camera were discussed,among which the mismatch error in VHR was found to be the main *** auto-compensation scheme for VHR was *** validity and effectiveness were proved by the on-orbit high quality images.

关键词： Chang'E-2 satellite CCD stereo camera TDI-CCD velocity-height ratio auto-compensation scheme

Genetic analysis and preimplantation genetic diagnosis of Chinese Marfan syndrome patients

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Journal of Genetics and Genomics 2019年第6期46卷 319-323页

作者： Meng Qin Xiaohui Zhu Zhe zhang Xuemin Li Zhiqiang Yan Yuqian Wang Shuo Guan Yihua He Wenxin zhang Liying Yan Jie qiao Xu Zhi Center for Reproductive Medicine Department of Obstetrics and Gynecology Peking University Third Hospital Beijing 100191 China National Clinical Research Center for Obstetrics and Gynecology Beijing 100191 China Key Laboratory of Assisted Reproduction (Peking University) Ministry of Education Beijing 100191 China Cardiac Surgery Department Peking University Third Hospital Beijing 100191 China Department of Ophthalmology Peking University Third Hospital Beijing 100191 China Department of Ultrasound Beijing Anzhen Hospital Capital Medical University Beijing China

Marfan syndrome (MFS)(OMIM 154700) is a relatively common autosomal dominant genetic disease that causes skeletal, ocular, and cardiovascular defects and was first described by a French pediatrician in 1896 (Bitterman and Sponseller, 2017). Its prevalence rate is 1/3000—1/5000, and more than 25% of cases are sporadic (Chiu et al., 2014). Studies have shown that about 90% of MFS is caused by variants in the fibrillin-1 gene (FBN1, OMIM 134797). FBN1, located on chromosome 15q21.1, encodes a macromolecular glycoprotein-fibrin 1, which aggregates to form microfibers in the extracellular matrix and distributes in various human connective tissues, such as periosteum, vessel wall, and crystal suspensor ligament. Variants in FNB1 have been reported in 65 exons, but the relationship between genotype and phenotype remains rather unclear (Sakai et al., 2016). Studies have also shown that patients with MFS and similar diseases may have variants in other related genes such as members of the transforming growth factor beta receptor (TGFBR) family (Mizuguchi et al., 2004;Sakai et al., 2006;Bolar et al., 2012;De Cario et al., 2018). For better prevention and treatment of MFS as well as for suspected MFS patients, there is a strong need for efficient genetic testing for early diagnosis and differential diagnoses of patients with related phenotypes (Aubart et al., 2018).

关键词： Marfan syndrome (MFS) cardiovascular defects French pediatrician

Functional and binding studies of gallic acid showing platelet aggregation inhibitory effect as a thrombin inhibitor

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Chinese Herbal Medicines 2022年第2期14卷 303-309页

作者： Yuxin zhang Xing Wang Binan Lu Yanbin Gao Yanling zhang Yatong Li Hongjuan Niu Lu Fan Zongran Pang Yanjiang qiao Key Laboratory of Ethnomedicine of Ministry of Education School of PharmacyMinzu University of ChinaBeijing 100081China Beijing Key Lab of Traditional Chinese Medicine Collateral Disease Theory Research School of Traditional Chinese MedicineCapital Medical UniversityBeijing 100069China Key Laboratory of TCM-Information Engineer of State Administration of TCM School of Chinese Materia MedicaBeijing University of Chinese MedicineBeijing 100029China

Objective:This study was devoted to identifying natural thrombin inhibitors from traditional Chinese medicine(TCM)and evaluating its biological activity in vitro and binding ***:A combination strategy containing molecular docking,thrombin inhibition assay,surface plasmon resonance(SPR)and molecular dynamics simulation were applied to verify the study ***:Gallic acid was confirmed as a direct thrombin inhibitor with IC;of 9.07μmol/L and showed a significant inhibitory effect on thrombin induced platelet ***-based binding studies demonstrated that gallic acid interacted with thrombin with a KDvalue of 8.29μmol/*** dynamics and binding free energy analysis revealed that thrombin-gallic acid system attained equilibrium rapidly with very low fluctuations,the calculated binding free energies was-14.61 kcal/***230,Glu232,Ser235,Gly258 and Gly260 were the main amino acid residues responsible for thrombin inhibition by gallic acid,providing a mechanistic basis for further ***:This study proved that gallic acid is a direct thrombin inhibitor with platelet aggregation inhibitory effect,which could provide a basis for the follow-up research and development for novel thrombin inhibitors.

关键词： gallic acid molecular dynamics natural thrombin inhibitor platelet aggregation surface plasmon resonance

Rice bran polysaccharide ameliorates ovalbumin-induced allergy and improves gut microbiota composition

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Food Science and Human Wellness 2024年

作者： Bingjie Chen Yongjin qiao Chong Wang Xiao Wang Yi zhang Linglin Fu School of Food Science and Biotechnology， Zhejiang Gongshang University Institute of Crop Breeding and Cultivation， Shanghai Academy of Agricultural Science

This study is the first investigation of the effects of polysaccharide extracted from rice bran (RBP) on ovalbumin (OVA)-induced allergy and the gut microbiota， which hasn't been reported previously. RBP in the medium-dose was found to significantly reduce the symptoms of food allergy (FA) in mice， lower the levels of histamine and allergen-specific (IgE)， and attenuate intestinal inflammation. Further studies demonstrated that RBP decreased allergy-associated responses in intestinal epithelial cells and Th2 cells while regulating Th1/Th2 differentiation to reach a dynamic equilibrium and downregulating Th2 polarization caused by allergies. Short-chain fatty acid (SCFAs) content and 16S rRNA sequencing revealed that RBP enhanced the abundance and diversity of the gut microflora and raised the content of SCFAs. These results suggest that RBP may mitigate FA by modulating the gut microbiota. This study revealed the effective use of rice bran and served as a basis for the development of innovative functional foods with anti-allergic properties.

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Dolomitization evolution and its effects on hydrocarbon reservoir formation from penecontemporaneous to deep burial environment

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Petroleum Exploration and Development 2022年第4期49卷 731-743页

作者： SHEN Anjiang LUO Xianying HU Anping qiao Zhanfeng zhang Jie PetroChina Hangzhou Institute of Petroleum Geology Hangzhou 310023China Key Laboratory of Carbonate Reservoirs CNPCHangzhou 310023China

Aiming at the scientific problem that only part of dolomite acts as dolomite reservoir,this paper takes the multiple dolomite-bearing formations in the Tarim and Ordos basins,NW China and Sichuan Basin,SW China as the study object,by means of mineral petrological analysis and geochemical methods including carbonate clumped isotope,U-Pb isotopic dating,etc.,to rebuild the dolomitization pathway and evaluate its effects on reservoir *** the basis of detailed rock thin section observation,five dolomitic structural components are identified,including original fabric-retained dolomite(microbial and/or micrite structure),buried metasomatic dolomite I(subhedral-euhedral fine,medium and coarse crystalline structure),buried metasomatic dolomite II(allotriomorphic-subhedral fine,medium and coarse crystalline structure),buried precipitation dolomite and coarse crystalline saddle *** them,the first three exist in the form of rocks,the latter two occur as dolomite minerals filling in pores and *** corresponding petrological and geochemical identification templates for them are *** on the identification of the five dolomitic structural components,six dolomitization pathways for three types of reservoirs(preserved dolomite,reworked dolomite and limestone buried dolomitization)are *** initial porosity of the original rock before dolomitization and the dolomitization pathway are the main factors controlling the development of dolomite *** preserved dolomite and reworked dolomite types have the most favorable dolomitization pathway for reservoir formation,and are large scale and controlled by sedimentary facies in development and distribution,making them the first choices for oil and gas exploration in deep carbonate formations.

关键词： dolomitization dolomitization pathway dolomite reservoir carbonates penecontemporaneous environment burial environment dolomite genesis identification template

部分相干高斯-谢尔模型光束在介质中传输的M^2因子

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光学学报 2006年第2期26卷 212-216页

作者：文侨张彬四川大学电子信息学院成都610064

在波数K为复数的情况下,对部分相干光强度二阶矩及M2因子的定义进行了修正。以部分相干高斯谢尔模型(GSM)光束为例,讨论了光束在介质中传输时M2因子的变化。研究结果表明,部分相干光束在增益或损耗介质中传输时的M2因子与光束在无增益... 详细信息

在波数K为复数的情况下,对部分相干光强度二阶矩及M2因子的定义进行了修正。以部分相干高斯谢尔模型(GSM)光束为例,讨论了光束在介质中传输时M2因子的变化。研究结果表明,部分相干光束在增益或损耗介质中传输时的M2因子与光束在无增益无损耗介质传输时的M2因子具有不同变化特性,此时,M2因子不仅只与部分相干光的相干参量β有关,且随着传输距离B和表征介质增益(或损耗)特征Ki的增大而增大(或减小);随着相干长度σ0的具体尺寸、波数实部Kr的减小而增大(或减小)。为控制光束质量提供几种有效的途径。

关键词：激光技术光束质量复数波数高斯-谢尔模型光束肝因子增益或损耗系数

Protective effect of thyroid and restores of ovarian function of Buzhong Yiqi granule(补中益气颗粒)on experimental autoimmune thyroiditis in female rats

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Journal of Traditional Chinese Medicine 2024年第2期44卷 315-323页

作者： WANG Yuezhu zhang Yuyang qiao Jiajun LU Yuyuan XIA Zhongyuan Graduate College Beijing University of Chinese MedicineBeijing 100029China Department of Surgery of Traditional Chinese Medicine China-Japan Friendship HospitalBeijing 100029China

OBJECTIVE:To observe the effects of Buzhong Yiqi granule(补中益气颗粒)on thyroid function and ovarian function in rats with experimental autoimmune thyroiditis(EAT).METHODS:EAT model was replicate by using the method of mixing and injecting porcine thyroglobulin with Freund's adjuvant and high *** were randomly divided into normal control(NC)group,EAT model(EAT)group,selenium yeast(PC)group,low dose Buzhong Yiqi(BZYQ-L)group,medium dose Buzhong Yiqi(BZYQ-M)group and high dose Buzhong Yiqi(BZYQ-H)*** two months of drug intervention according to dosage,enzyme-linked immunosorbent assay(ELISA)was used to measure the levels of free triiodothyronine(FT3),free thyroxine(FT4),thyroid-stimulating hormone(TSH),antithyroid peroxidase antibody(TPOAb),thyroglobulin antibody(TGAb)in peripheral blood of *** pathological changes of rat thyroid tissues were observed under light microscope with HE staining;ELISA was used to determine estradiol(E2),follicle-stimulating hormone(FSH),luteinizing hormone(LH),testosterone(T),antimüllerian hormone(AMH),and the pathological changes of rat ovarian tissues were observed under light microscope with hematoxylin and eosin ***:Compared with the NC group,BZYQ granule improved the thyroid and ovarian tissue morphology,and the levels of TPOAb,TGAb and TSH in the model group rats significantly increased(P<0.05),the thyroid tissue was severely destroyed,the levels of E2,FSH,LH,T,AMH significantly increased(P<0.05),and the ovary exhibited polycystic changes;Compared with the model group,TSH level in the BZYQ-L group rats decreased(P<0.05),FSH,T,AMH levels decreased(P<0.05),in the BZYQ-M group TPOAb,TSH levels decreased(P<0.05),FSH,LH,T,AMH levels significantly decreased(P<0.05),BZYQ-H group TPOAb,TGAb,TSH levels significantly decreased(P<0.05),FSH,LH,T,AMH levels significantly decreased(P<0.05),with the greatest improvement and significantly better than selenium yeast group(P<0.05).CONCLUSIONS:BZYQ granule could regulate th

关键词： thyroiditis autoimmune thyroid function tests gonadal steroid hormones thyroid antibody Buzhong Yiqi granule

Three-Body Photodissociation of Thionyl Chloride

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Chinese Journal of Chemical Physics 2018年第3期31卷 257-262,367页

作者： Bumaliya Abulimiti qiao-li Hao Chen Qin Mei Xiang Bing zhang College of Physics and Electronic Engineering Xinjiang Normal UniversityUrumqi 830054China State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Wuhan Institute of Physics and MathematicsChinese Academy of SciencesWuhan 430071China

The ultrafast photodissociation dynamics of thionyl chloride after excitation with a 235 nm pump pulse has been studied using a femtosecond time-resolved mass *** observed parent transient suggests that the excited states initiated by 235 nm are very shortlived,that is,approximately 166 *** only a stepwise three-body dissociation pathway but also a concerted three-body dissociation pathway is observed.

关键词： Photodissociation Thionyl chloride Three-body Time-resolved study