检索结果-南通市图书馆

工程建设与设计 2024年第6期 158-160页

作者：郑文强石家庄市公路桥梁建设集团有限公司石家庄050000

为研究注浆加固处理技术在高速公路路基施工中的应用,论文详细阐述了路基沉陷类型及产生的主要原因,介绍了路基注浆加固技术的工程特性及分类,结合实际工程,重点研究了路基注浆加固施工技术要点,并对其施工质量进行检测。

关键词：高速公路路基工程沉陷注浆加固

ZSM-5浸渍Zn催化甲醇耦合轻烃改质芳构化反应研究

在线全文

学校读者我要写书评

暂无评论

聚酯工业 2024年第2期37卷 8-11页

作者：杜文强中国石油乌鲁木齐石化公司新疆乌鲁木齐830019

采用等体积浸渍法,对ZSM-5分子筛进行了4种不同质量分数Zn的负载改性,并对浸渍Zn的ZSM-5分子筛样品进行了XRD、N2-吸脱附和NH3-TPD表征和催化甲醇耦合轻烃改质芳构化反应研究。研究结果证明:ZSM-5分子筛样品浸渍Zn后比表面积、孔体积和... 详细信息

采用等体积浸渍法,对ZSM-5分子筛进行了4种不同质量分数Zn的负载改性,并对浸渍Zn的ZSM-5分子筛样品进行了XRD、N2-吸脱附和NH3-TPD表征和催化甲醇耦合轻烃改质芳构化反应研究。研究结果证明:ZSM-5分子筛样品浸渍Zn后比表面积、孔体积和酸量减少,并且随着浸渍Zn质量分数的增大,比表面积、孔体积和酸量减少越大,这可能是由于分子筛引入锌物种后,锌物种堵塞孔道,导致其比表面积和孔体积缩小;400℃,0.4 MPa(N_(2)),质量空速为1.0 h-1(甲醇:抽余油=1:1)时,负载Zn后ZSM-5分子筛催化剂的催化性能得到提高,在负载量为2.0%时,ZSM-5分子筛催化剂具有最优的催化性能,此时甲醇转化率100%,芳烃选择性34.18%,辛烷值91(RON),证实浸渍Zn后有利于甲醇耦合轻烃改质芳构化反应的发生。

关键词： Zn ZSM-5 甲醇轻烃耦合

在线全文

学校读者我要写书评

暂无评论

首批阿戈美拉汀国家对照品的研制

中国新药杂志 2024年第14期33卷 1482-1488页

作者：孙长迎文强张燕霞尹利辉中国食品药品检定研究院北京102629 国家药品监督管理局化学药品质量研究与评价重点实验室北京102629 江苏豪森药业集团有限公司连云港222000

目的:建立定性和定量用阿戈美拉汀的首批国家对照品。方法:应用IR光谱、气质联用及NMR技术对阿戈美拉汀进行结构确证。采用HPLC法测定纯度并且对均匀性、稳定性进行研究,并测定干燥失重、炽灼残渣、热重分析等,通过质量平衡法计算阿戈... 详细信息

目的:建立定性和定量用阿戈美拉汀的首批国家对照品。方法:应用IR光谱、气质联用及NMR技术对阿戈美拉汀进行结构确证。采用HPLC法测定纯度并且对均匀性、稳定性进行研究,并测定干燥失重、炽灼残渣、热重分析等,通过质量平衡法计算阿戈美拉汀含量。结果:确证阿戈美拉汀的结构,确定首批阿戈美拉汀对照品含量为99.9%,与核磁定量法测定的结果、高氯酸非水滴定结果、差示扫描量热法(differential scanning calorimetry, DSC)结果基本一致。结论:首批阿戈美拉汀国家对照品的研制可作为阿戈美拉汀原料及其相关制剂的鉴别和含量测定用对照品。

关键词：阿戈美拉汀对照品含量测定 HPLC法质量平衡法

在线全文

学校读者我要写书评

暂无评论

红花油茶新品种‘阳春白雪’

园艺学报 2024年第S1期51卷 207-208页

作者：汪雁楠查康王波黄彬温强江西省林业科学院油茶资源培育与利用江西省重点实验室南昌330032

‘阳春白雪’是从红花油茶(Camellia chekiangoleosa Hu.)天然林分里发现的少量白花变异植株中选育而来。花白色,碗形,花瓣6~7片,单瓣,中型花,花冠直径6.7~11.5 cm,花期在2—3月。叶片革质,中等厚度,边缘细齿状,椭圆形。适宜在长江以南... 详细信息

‘阳春白雪’是从红花油茶(Camellia chekiangoleosa Hu.)天然林分里发现的少量白花变异植株中选育而来。花白色,碗形,花瓣6~7片,单瓣,中型花,花冠直径6.7~11.5 cm,花期在2—3月。叶片革质,中等厚度,边缘细齿状,椭圆形。适宜在长江以南各省区栽培。

关键词：红花油茶品种

Rees-Shishikura's Theorem for Geometrically Finite Rational Maps

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2017年第12期33卷 1587-1596页

作者： wen qiang SHEN Department of Mathematical Sciences Tsinghua University Beijing 100084 P. R. China

In this paper, we generalize Rees-Shishikura＇s theorem to the class of geometrically finite rational maps.

关键词： Geometrically finite rational map Rees-Shishikura's theorem homeomorphism

积雪苷霜软膏联合点阵CO_(2)激光治疗面部烧伤后增生性瘢痕疗效观察

在线全文

学校读者我要写书评

暂无评论

中国美容医学 2024年第6期33卷 85-88页

作者：文强杨加保宿迁市第一人民医院烧伤整形科江苏宿迁223800

目的:探究积雪苷霜软膏联合点阵CO_(2)激光对面部烧伤后增生性瘢痕(Hypertrophic scar,HS)的临床疗效。方法:选取2020年7月-2022年7月宿迁市第一人民医院收治的80例面部烧伤后HS患者为研究对象,按照随机数字表法将其分为对照组(n=40)和... 详细信息

目的:探究积雪苷霜软膏联合点阵CO_(2)激光对面部烧伤后增生性瘢痕(Hypertrophic scar,HS)的临床疗效。方法:选取2020年7月-2022年7月宿迁市第一人民医院收治的80例面部烧伤后HS患者为研究对象,按照随机数字表法将其分为对照组(n=40)和观察组(n=40),对照组给予点阵CO_(2)激光治疗,观察组在对照组基础上联合积雪苷霜软膏治疗,连续治疗6个月,比较两组患者临床疗效,以及治疗前后改良温哥华瘢痕评估量表(Modified Vancouver scar scale,mVSS)、瘢痕血流灌注量、瘢痕厚度和烧伤健康量表(Burns specific health scale-brief,BSHS-B)评分,记录不良反应发生情况。结果:观察组临床总有效率(92.50%)较对照组(72.50%)高(P0.05),治疗后,两组患者上述评分均降低,且观察组较对照组更低(P0.05),治疗后,两组患者瘢痕血流灌注量、瘢痕厚度均降低,BSHS-B各维度评分均升高,且观察组优于对照组(P0.05)。结论:面部烧伤后HS患者应用积雪苷霜软膏联合点阵CO_(2)激光治疗,疗效显著,可明显改善mVSS评分、瘢痕血流灌注量及瘢痕厚度,提高生存质量,且安全性良好。

关键词：烧伤增生性瘢痕积雪苷霜软膏点阵二氧化碳激光瘢痕厚度瘢痕血流灌注量

Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia:randomized trials and multiomics analysis

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Military Medical Research 2024年第1期11卷 19-33页

作者： Liang-Kun Guo Yi Su Yu-Ya-Nan Zhang Hao Yu Zhe Lu wen-qiang Li Yong-Feng Yang Xiao Xiao Hao Yan Tian-Lan Lu Jun Li Yun-Dan Liao Zhe-Wei Kang Li-Fang Wang Yue Li Ming Li Bing Liu Hai-Liang Huang Lu-Xian Lv Yin Yao Yun-Long Tan Gerome Breen Ian Everall Hong-Xing Wang Zhuo Huang Dai Zhang Wei-Hua Yue Institute of Mental Health Peking University Sixth HospitalBeijing 100191China National Clinical Research Center for Mental Disorders Peking University Sixth HospitalBeijing 100191China NHC Key Laboratory of Mental Health and Research Unit of Diagnosis and Treatment of Mood Cognitive Disorder(2018RU006) Chinese Academy of Medical SciencesBeijing 100191China Peking University Huilongguan Clinical Medical School Beijing Huilongguan HospitalBeijing 100096China Department of Psychiatry Jining Medical UniversityJining 272067ShandongChina Henan Key Lab of Biological Psychiatry the Second Affiliated Hospital of Xinxiang Medical UniversityXinxiang 435001HenanChina Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province Kunming Institute of ZoologyChinese Academy of SciencesKunming 650223China Institute of Psychiatry Psychology and NeuroscienceKing’s College LondonLondon WC2R 2LSUK State Key Laboratory of Cognitive Neuroscience and Learning Beijing Normal UniversityBeijing 100875China Analytic and Translational Genetics Unit Massachusetts General HospitalBostonMA 02114USA Stanley Center for Psychiatric Research the Broad Institute of MIT and HarvardCambridgeMA 02141USA Department of Medicine Harvard Medical SchoolBostonMA 02115USA Department of Biostatistics and Computational Biology School of Life SciencesFudan UniversityShanghai 200438China Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijing 100053China State Key Laboratory of Natural and Biomimetic Drugs Key Laboratory for Neuroscience for Ministry of EducationSchool of Pharmaceutical SciencesPeking University Health Science CenterBeijing 100191China PKU-IDG/McGovern Institute for Brain Research Peking UniversityBeijing 100871China Chinese Institute for Brain Research Beijing 102206China

Background:Choosing the appropriate antipsychotic drug(APD)treatment for patients with schizophrenia(SCZ)can be challenging,as the treatment response to APD is highly variable and difficult to predict due to the lack of effective *** studies have indicated the association between treatment response and genetic and epigenetic factors,but no effective biomarkers have been ***,further research is imperative to enhance precision medicine in SCZ ***:Participants with SCZ were recruited from two randomized *** discovery cohort was recruited from the CAPOC trial(n=2307)involved 6 weeks of treatment and equally randomized the participants to the Olanzapine,Risperidone,Quetiapine,Aripiprazole,Ziprasidone,and Haloperidol/Perphenazine(subsequently equally assigned to one or the other)*** external validation cohort was recruited from the CAPEC trial(n=1379),which involved 8 weeks of treatment and equally randomized the participants to the Olanzapine,Risperidone,and Aripiprazole ***,healthy controls(n=275)from the local community were utilized as a genetic/epigenetic *** genetic and epigenetic(DNA methylation)risks of SCZ were assessed using the polygenic risk score(PRS)and polymethylation score,*** study also examined the genetic-epigenetic interactions with treatment response through differential methylation analysis,methylation quantitative trait loci,colocalization,and promoteranchored chromatin *** learning was used to develop a prediction model for treatment response,which was evaluated for accuracy and clinical benefit using the area under curve(AUC)for classification,R^(2) for regression,and decision curve ***:Six risk genes for SCZ(LINC01795,DDHD2,SBNO1,KCNG2,SEMA7A,and RUFY1)involved in cortical morphology were identified as having a genetic-epigenetic interaction associated with treatment *** developed and externally validated predictio

关键词： Schizophrenia Antipsychotic drug Treatment response Prediction model Genetics Epigenetics

Mammals of Gaoligong Mountain in China:Diversity,distribution,and conservation

在线全文

学校读者我要写书评

暂无评论

Zoological Research(Diversity and Conservation) 2024年第1期1卷 3-19页

作者： Quan Li Xue-You Li wen-qiang Hu wen-Yu Song Shui-Wang He Hong-Jiao Wang Zhe-Chang Hu Meng-Cheng Li Kenneth Otieno Onditi Zhong-Zheng Chen Chang-Zhe Pu Yun Xiong Cai-Hong Rao Fu-You Zhang Chang-Sheng Zuo Xue-Long Jiang State Key Laboratory of Genetic Resources and Evolution&Yunnan Key Laboratory of Biodiversity and Ecological Conservation of Gaoligong Mountain Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China Gaoligong Mountain Forest Ecosystem Observation and Research Station of Yunnan Province&Dulongjiang Forest Ecosystem Research Station KunmingYunnan 650223China University of Chinese Academy of Sciences Beijing 101408China Vector Laboratory Institute of Pathogens and VectorsYunnan Provincial Key Laboratory for Zoonosis Control and PreventionDali UniversityDaliYunnan 671000China School of Ecology and Environment Anhui Normal UniversityWuhuAnhui 241002China Gongshan Administrative Sub-Bureau of Gaoligongshan National Nature Reserve NujiangYunnan 673500China Fugong Administrative Sub-Bureau of Gaoligongshan National Nature Reserve NujiangYunnan 673400China Baoshan Administrative Bureau of Gaoligongshan National Nature Reserve BaoshanYunnan 678000China Administrative Bureau of Tongbiguan Provincial Nature Reserve DehongYunnan 679300China

Gaoligong Mountain(hereafter,GLGM)is located at the intersection of Myanmar and China’s Yunnan Province and Xizang Zizhiqu,and spans three globally significant biodiversity hotspots:the Himalayas,Indo-Burma,and the Mountains of Southwest *** surveys of mammals in this ecologically important region have a long history,there is no comprehensive systematic checklist and distribution account of the mammals of ***,we compiled a mammal species checklist of GLGM based on thorough field investigations and literature *** also examined specimen collections and applied camera trapping surveys to explore the region’s mammal diversity and distribution *** recorded 212 mammal species in nine orders,33 families,and 119 genera,which accounts for 30.5%of China’s mammal species,and a high proportion of nationally protected(50)and globally threatened(29)*** species richness showed a symmetrical unimodal curve along the elevation gradient,peaking at intermediate elevations(2000 to 2500 m above sea level(asl)),and increasing generally from south to north,slightly higher in the east slope than in the *** analysis and non-metric multidimensional scaling revealed three distinct elevational assemblages(3500 m asl)and significant south-to-north variation,but no substantial differences between the east and west *** GLGM present a unique conservation value due to the high proportions of rare and endangered mammal species,complex faunal composition,high endemism,and being the distribution boundary for many *** study is an important phased account of mammal diversity in GLGM and makes a prospect for future research.

关键词： Biodiversity hotspot Eastern Himalaya Gaoligong Mountain Endemism Mammal conservation Hengduan Mountains

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于异构平台的卷积神经网络加速系统设计

计算机工程与科学 2024年第1期46卷 12-20页

作者：秦文强吴仲城张俊李芳安徽大学物质科学与信息技术研究院安徽合肥230601 中国科学院合肥物质科学研究院强磁场科学中心安徽合肥230031 强磁场安徽省实验室安徽合肥230031

在计算和存储资源受限的嵌入式设备上部署卷积神经网络,存在执行速度慢、计算效率低、功耗高的问题。提出了一种基于异构平台的新型卷积神经网络加速架构,设计并实现了基于MobileNet的轻量化卷积神经网络加速系统。首先,为降低硬件资源... 详细信息

在计算和存储资源受限的嵌入式设备上部署卷积神经网络,存在执行速度慢、计算效率低、功耗高的问题。提出了一种基于异构平台的新型卷积神经网络加速架构,设计并实现了基于MobileNet的轻量化卷积神经网络加速系统。首先,为降低硬件资源消耗以及数据传输成本,采用动态定点数量化和批标准化融合的设计方法,对网络模型进行了优化,并降低了加速系统的硬件设计复杂度;其次,通过实现卷积分块、并行卷积计算、数据流优化,有效提高了卷积运算效率和系统吞吐率。在PYNQ-Z2平台上的实验结果表明,此加速系统实现的MobileNet网络推理加速方案对单幅图像的识别时间为0.18 s,系统功耗为2.62 W,相较于ARM单核处理器加速效果提升了128倍。

关键词：现场可编程门阵列(FPGA) Vivado高层次综合卷积神经网络异构平台硬件加速

Design,Synthesis and Electrochromic Properties of Anthraquinone Imide-based Donor-acceptor Type of Near Infrared Chromophores

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2012年第2期28卷 239-241页

作者： QIAO wen-qiang Key Laboratory of Materials Behaviors and Evaluation Technology in Space Environments Harbin Institute of TechnologyHarbin 150001P.R.China

A new series of near infrared（NIR） electrochromic anthraquinone imides containing a triphenylamine moiety as an electron donor was synthesized and their electrochemical and spectroelectrochemical behavior were *** results show that the new anthraquinone imides are redox active which can be reduced electrochemically from the neutral state to the radical anion form that absorbs in a range of 700―1200 nm.

关键词： Anthraquinone imide Triphenylamine moiety Near infrared electrochromism