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Personal continuous route pattern mining

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第2期10卷 221-231页

作者： qian ye Ling CHEN Gen-cai CHEN School of Computer Science and Technologym Zhejiang University Hangzhou 310027 China

In the daily life,people often repeat regular routes in certain periods. In this paper,a mining system is developed to find the continuous route patterns of personal past trips. In order to count the diversity of personal moving status,the mining system employs the adaptive GPS data recording and five data filters to guarantee the clean trips data. The mining system uses a client/server architecture to protect personal privacy and to reduce the computational load. The server conducts the main mining procedure but with insufficient information to recover real personal routes. In order to improve the scalability of sequential pattern mining,a novel pattern mining algorithm,continuous route pattern mining(CRPM),is proposed. This algorithm can tolerate the different disturbances in real routes and extract the frequent patterns. Experimental results based on nine persons' trips show that CRPM can extract more than two times longer route patterns than the traditional route pattern mining algorithms.

关键词： Data mining Route pattern GPS Mobile phone

基于50BiN望远镜的疏散星团NGC 7789的变星搜寻研究

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西华师范大学学报（自然科学版） 2025年第1期46卷 79-85页

作者：叶倩王坤彭宇慧西华师范大学物理与天文学院四川南充637009

基于西华师范大学50BiN望远镜获得的长时序测光观测数据,在疏散星团NGC 7789及其周围的20′×20′视场中搜寻到19颗变星,其中10颗是本次观测发现的。基于变星在NGC 7789颜色星等图上的位置、星团成员星概率和Gaia视差,对这19颗变星的星... 详细信息

基于西华师范大学50BiN望远镜获得的长时序测光观测数据,在疏散星团NGC 7789及其周围的20′×20′视场中搜寻到19颗变星,其中10颗是本次观测发现的。基于变星在NGC 7789颜色星等图上的位置、星团成员星概率和Gaia视差,对这19颗变星的星团成员星性质进行初步分析。结果表明,17颗变星可能是星团成员,2颗可能是场星。根据变星光变曲线的形状,周期的长度以及在颜色星等图上的位置,对这19颗变星的分类进行了初步讨论。结果表明,13颗是短周期变星(3颗δ Scuti, 7颗食双星、3颗未知类型变星),6颗是长周期变星。研究扩大了星团变星的样本数量,为开展单个变星的星震学研究和星团变星的统计研究奠定了基础。

关键词： 50BiN 疏散星团变星 NGC 7789 δScuti

Preclinical and clinical trials of oncolytic vaccinia virus in cancer immunotherapy:a comprehensive review

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Cancer Biology & Medicine 2023年第9期20卷 646-661页

作者： Mengyuan Li Minghuan Zhang qian ye Yunhua Liu Wenbin qian Department of Hematology the Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Hangzhou Rong-Gu Biotechnology Limited Company Hangzhou 310056China Department of Pathology&Pathophysiology and Department of Surgical Oncology of the Second Affiliated Hospital Zhejiang University School of MedicineHangzhou 310058China

Oncolytic virotherapy has emerged as a promising treatment for human cancers owing to an ability to elicit curative effects via systemic *** cells often create an unfavorable immunosuppressive microenvironment that degrade viral structures and impede viral replication;however,recent studies have established that viruses altered via genetic modifications can serve as effective oncolytic agents to combat hostile tumor ***,oncolytic vaccinia virus(OVV)has gained popularity owing to its safety,potential for systemic delivery,and large gene insertion *** review highlights current research on the use of engineered mutated viruses and gene-armed OVVs to reverse the tumor microenvironment and enhance antitumor activity in vitro and in vivo,and provides an overview of ongoing clinical trials and combination *** addition,we discuss the potential benefits and drawbacks of OVV as a cancer therapy,and explore different perspectives in this field.

关键词： Oncolytic virotherapy oncolytic vaccinia virus engineered virus arming strategy

Interannual and interdecadal variabilities in SST anomaly over the eastern equatorial Pacific

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Chinese Science Bulletin 1999年第6期44卷 568-571页

作者： Weihong qian Yafen Zhu qian ye Peking Univ Dept Geophys Beijing 100871 Peoples R China Chinese Acad Sci Inst Atmospher Phys Beijing 100029 Peoples R China

Abstract The global sea surface temperature (SST) anomaly data from 1950 to 1996 were used to analyze spatial characters of interdecadal SST variations. A wavelet transform was made for the equatorial eastern Pacific SST anomaly time series. Results show that there are three remarkable timescale SST variations. 130-month interdecadal variation, 57-month interannual variation and 28-month quasi2-a variation. Based on this result, an El Nio event was predicted in the early part of 1997.

关键词： SST anomaly interannual variation interdecadal variation prediction.

A New Goal for Playing Global Climate Change Game

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International Journal of Disaster Risk Science 2010年第2期1卷 40-43页

作者： qian ye Peijun Shi State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal UniversityBeijing 100875China

From an integrated risk governance point of view, we propose a new goal in order to solve the current dilemma in the international global climate change negotiations. We demonstrate that for global climate change issues, identifying a common interest so that all players are willing to play the game with the same rule is the key. Green economy could be that key.

关键词： climate Global Climate

MRI联合AFP-L3预测肝癌射频消融术后复发的研究

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中国CT和MRI杂志 2025年第1期23卷 116-118页

作者：刘丽翁彩云钱烨海安市人民医院肿瘤化疗科江苏海安226600

目的本研究探讨血清凝集素反应性甲胎蛋白(serum lectin-reactive alpha-fetoprotein,AFP-L3)结合M RI预测经皮射频消融(radiofrequency ablation,RFA)后肝癌复发的价值。方法纳入94例肝癌RFA患者和82名健康人。磁共振成像记录表观弥... 详细信息

目的本研究探讨血清凝集素反应性甲胎蛋白(serum lectin-reactive alpha-fetoprotein,AFP-L3)结合M RI预测经皮射频消融(radiofrequency ablation,RFA)后肝癌复发的价值。方法纳入94例肝癌RFA患者和82名健康人。磁共振成像记录表观弥散系数(apparent diffusion Coefficient, ADC),定量测定所有受试者血清AFP-L3的浓度,分析其与治疗后临床疗效的相关性和预测作用。结果肝癌患者血清AFP-L3水平高于健康对照组,ADC值低于健康对照组。肿瘤残留者的ADC值低于完全消融者,血清AFP-L3水平高于完全消融者,联合检测ADC值和血清AFP-L3水平诊断完全消融的敏感性和特异度分别为87.50%和87.18%,肿瘤结节数、肿瘤直径、AFP、AFP-L3和有无肝硬变均为肝癌术后1年内复发的独立危险因素。ADC值与血清AFP-L3水平联合检测对预测肝癌复发的敏感性为92.86%,特异性为69.62%。结论 ADC值与血清AFP-L3检测相结合,对射频治疗后肝癌的完全消融和复发有较好的预测作用。

关键词： MRI 血清凝集素甲胎蛋白肝癌射频消融术

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Effect of medical care linkage-continuous management mode in patients with posterior circulation cerebral infarction undergoing endovascular interventional therapy

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World Journal of Clinical Cases 2022年第29期10卷 10478-10486页

作者： Fen-Xia Zhu qian ye Department of Interventional Medicine The First Affiliated Hospital of Soochow UniversitySuzhou 215006Jiangsu ProvinceChina

BACKGROUND Acute cerebral infarction is a severe type of ischemic stroke that can be divided into anterior circulation cerebral infarction and posterior circulation cerebral infarction(PCCI).PCCI affects the structure of the posterior circulation brain,because posterior part of the brain,which has more complex anatomical structures and more prone to posterior circulation vascular ***,improving the prognosis of PCCI patients is *** To explore the effect of medical care linkage-continuous management mode(MCLMM)on endovascular interventional therapy(EIT)for *** Sixty-nine patients with PCCI who received EIT and conventional nursing intervention were selected as the control group,and 78 patients with PCCI who received EIT and MCLMM intervention were selected as the observation *** incidence of postoperative complications,compliance and disease selfmanagement behavior after six months of intervention,modified Rankin scale(mRS)and Barthel index(BI)scores in the acute phase and after one year of intervention,and recurrence within one year were compared between the two *** The total incidence rate of postoperative complications in the observation group(7.69%)was lower than that in the control group(18.84%)(Pyear of intervention,in the observation group,the mRS score was significantly lower,and the BI score was significantly higher than those in the control group(Pyear in the observation group(3.85%)was significantly lower than that in the control group(13.04%)(P<0.05).CONCLUSION MCLMM can reduce the incidence of complications after EIT for PCCI,improve patient compliance behavior and disease se

关键词： Medical care linkage-continuous management mode Posterior circulation cerebral infarction Cerebral infarction Medical care Interventional therapy

Zircon U–Pb age and geochemical constraints on the origin and tectonic implication of the Tuotuohe Cenozoic alkaline magmatism in Qinghai–Tibet Plateau

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Acta Geochimica 2020年第1期39卷 67-84页

作者： ye qian Shengnan Tian Yujin Li Fengyue Sun College of Earth Sciences Jilin UniversityChangchunChina Key Laboratory of Mineral Resources Evaluation in Northeast Asia Ministry of Natural Resources of the People's Republic of ChinaChangchunChina

A large number of Eocene-Oligocene alkaline/alkali-rich igneous rocks were developed in the Tuotuohe region of the Qinghai-Tibetan *** this study,we present zircon U-Pb ages,Hf isotope data,and major and trace element compositions of the Cenozoic alkaline rocks from the Tuotuohe region in order to constraint the petrogenesis and tectonic evolution history of qiangtang *** U-Pb ages were measured via LA-ICP-MS to be39.6,37.6 and 32.0 *** 39.6 Ma trachyte was characterized by low SiO2 and high K2O and MgO *** 37.6 and 32.0 Ma orthophyres show enrichment in SiO2 and K2O,but deficient in *** of the samples belong to the alkaline *** rocks display enrichment in REE,LREE,and LILE,depletion in HFSE,and no obvious Eu *** and geochemical features suggest that there were two possible mechanisms for the origin of the alkaline rocks in the Tuotuohe region:(1)the removed mafic lower crust dropped into the asthenosphere,forming the mix magma(Nariniya trachyte);(2)the upwelling asthenosphere triggered the crustal melting(Nariniya and Zamaqu orthophyre).The Eocene-Oligocene alkaline rocks in the study and adjacent areas are likely to be the result of the same tectonic-magmatic event of deep lithospheric evolution that is the crustal material melting triggered by lithospheric *** conclusion extends the influence scope of lithospheric delamination eastward to the Tuotuohe region(*92°E)from Banda Co(*82°E).

关键词： Zircon U-Pb chronology Zircon Hf isotopic Delamination Tuotuohe region Qinghai–Tibetan Plateau

A novel way towards CdS sensitized TiO_2 nanoparticles

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Chinese Chemical Letters 2010年第8期21卷 1003-1006页

作者： Jianhua Wang qian ye Xiaobo Wang Feng Zhou State Key Laboratory of Solid Labrication Lanzhou Institute of Chemical Physics Chinese Academy of Sciences Lanzhou 730000 China Graduate School of Chinese Academy of Sciences Beijing 100039 China Navy institute of Logistic Technology and Equipment Beijing 100072 China

Polymethyl methacrylate cadmium was grafted on TiO2 surface via the surface initiated atomic transfer radical polymerization of methyl methacrylate cadmium from a surface tether *** coordinated cadmium as the source precursor reacts with H2S generates CdS nanoscrystal on TiO2 *** grain size of CdS is about 5 nm and stabilized by tether polymer *** light absorption of CdS/TiO2 is expanded to visible light region.

关键词： Titanium oxide CdS nanocrystal Sensitization Light absorption