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NONLINEAR RESPONSES OF A FLUID-CONVEYING PIPE EMBEDDED IN NONLINEAR ELASTIC FOUNDATIONS

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Acta Mechanica Solida Sinica 2008年第2期21卷 170-176页

作者： Qin qian Lin Wang qiao Ni Department of Mechanics Huazhong University of Science and Technology Wuhan 430074 China

The nonlinear responses of planar motions of a fluid-conveying pipe embedded in nonlinear elastic foundations are investigated via the differential quadrature method discretization （DQMD） of the governing partial differential equation. For the analytical model, the effect of the nonlinear elastic foundation is modeled by a nonlinear restraining force. By using an iterative algorithm, a set of ordinary differential dynamical equations derived from the equation of motion of the system are solved numerically and then the bifurcations are analyzed. The numerical results, in which the existence of chaos is demonstrated, are presented in the form of phase portraits of the oscillations. The intermittency transition to chaos has been found to arise.

关键词： fiuid-conveying pipe nonlinear elastic foundation chaotic motion bifurcation differential quadrature method discretization (DQMD)

Nonlinear Degenerate Parabolic Equations with Time-dependent Singular Potentials for Baouendi–Grushin Vector Fields

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Acta Mathematica Sinica,English Series 2015年第1期31卷 123-139页

作者： Jun qiang HAN qian qiao GUO Department of Applied Mathematics Northwestern Polytechnical University

In this paper, we are concerned with the following three types of nonlinear degenerate parabolic equations with time-dependent singular potentials： uq/ t=▽α·（‖z‖^-pγ｜▽αu｜^p-2▽αu）＋V（z, t）u^p-1, uq/ t=▽α·（‖z‖^-2γ▽αu^m）＋V（z, t）u^m, uq/ t=u^μ▽α·（u^τ｜▽αu｜^p-2▽αu）＋V（z, t）u^p-1＋μ＋τin a cylinder Ω×（0, T） with initial condition u（z, 0）=u0（z） ≥ 0 and vanishing on the boundary Ω×（0, T）, where Ω is a Carnot-Carathéodory metric ball in Rd＋k and the time-dependent singular potential function is V（z, t） ∈ L^1loc （Ω×（0, T））. We investigate the nonexistence of positive solutions of these three problems and present our results on nonexistence.

关键词： Nonlinear degenerate parabolic equations Baouendi-Grushin vector fields positive solu-tions~ nonexistence Hardy inequality

A review of clinical reasoning in nursing education:based on high-fidelity simulation teaching method

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Frontiers of Nursing 2018年第3期5卷 175-183页

作者： qiao-qian Luo Marcia A Petrini School of Health Sciences Wuhan University Hope School of Nursing Wuhan University

Objective： Clinical reasoning is an essential feature of health care practice; it is also a crucial ability for providing patient care of high quality. It has been identified that graduate nurses may lack the clinical reasoning skills to deliver safe and effective patient cam. It is therefore of paramount importance to enhance nursing students＇ clinical reasoning ability. High-fidelity simulation （HFS） is proved to be an effective teaching and learning method, which may also have some advantages over other teaching methods. Methods： The authors retrospectively reviewed the related literature, illustrated the application of high-fidelity simulation teaching method in nursing education, putting the focus on the use of it in teaching with clinical reasoning. Results： The application of high-fidelity simulation to nursing education can simulate the clinical situation, thus to create a safe, continuous and efficient learning environment for students, and it can effectively improve students＇ clinical reasoning ability. Conclusions： high-fidelity simulation is effective for clinical reasoning teaching in nursing education. The extension of its application in China should be of great value. The relevant further study is suggested focusing on how to overcome its own limitations and have it better applied in nursing education in China.

关键词： clinical reasoning high-fidelity simulation nursing education teaching method

The use of machine learning to predict the effects of cryoprotective agents on the GelMA-based bioinks used in extrusion cryobioprinting

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Bio-Design and Manufacturing 2023年第4期6卷 464-477页

作者： qian qiao Xiang Zhang Zhenhao Yan Chuanyu Hou Juanli Zhang Yong He Na Zhao Shujie Yan Youping Gong qian Li School of Mechanics and Safety Engineering Zhengzhou UniversityZhengzhou 450001China State Key Laboratory of Fluid Power and Mechatronic Systems Zhejiang UniversityHangzhou 310027China NMPA Key Laboratory for Quality Control of In Vitro Diagnostics Henan Institute of Medical Device InspectionsZhengzhou 450003China School of Mechanical Engineering Hangzhou Dianzi UniversityHangzhou 310018China National Center for International Joint Research of Micro-Nano Molding Technology Zhengzhou UniversityZhengzhou 450001China Key Laboratory for Micro Molding Technology of Henan Province Zhengzhou UniversityZhengzhou 450001China

Cryobioprinting has tremendous potential to solve problems to do with lack of shelf availability in traditional bioprinting by combining extrusion bioprinting and *** order to ensure the viability of cells in the frozen state and avoid the possible toxicity of dimethyl sulfoxide(DMSO),DMSO-free bioink design is critical for achieving successful cryobioprinting.A nontoxic gelatin methacryloyl-based bioink used in cryobioprinting is composed of cryoprotective agents(CPAs)and a buffer *** selection and ratio of CPAs in the bioink directly affect the survival of cells in the frozen ***,the development of universal and efficient cryoprotective bioinks requires extensive *** first compared two commonly used CPA formulations via experiments in this *** show that the effect of using ethylene glycol as the permeable CPA was 6.07%better than that of *** datasets were obtained and four machinelearning models were established to predict experimental *** predictive powers of multiple linear regression(MLR),decision tree(DT),random forest(RF),and artificial neural network(ANN)approaches were compared,suggesting an order of ANN>RF>DT>*** final selected ANN model was then applied to another *** reveal that this machine-learning method can accurately predict the effects of cryoprotective bioinks composed of different *** also suggest that the formulations presented here have *** findings are likely to greatly accelerate research and development on the use of bioinks for cryobioprinting.

关键词： Cryobioprinting Cryoprotective bioink 3D bioprinting Machine learning Artificial intelligence Prediction model

The WRKY transcription factor PlWRKY65 enhances the resistance of Paeonia lactiflora(herbaceous peony)to Alternaria tenuissima

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Horticulture Research 2020年第1期7卷 2092-2103页

作者： Xue Wang Junjie Li Jing Guo qian qiao Xianfeng Guo Yan Ma College of Forestry Shandong Agricultural UniversityNo.61Daizong Road271018 Tai’anShandongChina Shandong Provincial Research Center of Demonstration Engineering Technology for Urban and Rural Landscapes 271018 Tai’anShandongChina Shandong Institute of Pomology 271000 Tai’anShandongChina

In this study,the disease resistance gene PlWRKY65 was isolated from the leaves of Paeonia lactiflora and analyzed by bioinformatics methods,and the localization of the encoded protein was *** real-time PCR(qRTPCR)was also used to explore the response of this gene to Alternaria *** results showed that the gene sequence contained multiple cis-acting elements involved in the response to hormone signaling molecules belonging to the IIe subgroup of the WRKY family,and the encoded proteins were located in the *** PlWRKY65 gene has a positive regulatory effect on *** *** silencing the PlWRKY65 gene via virus-induced gene silencing(VIGS),it was found that the gene-silenced plants were more sensitive to *** infection than the wild plants,exhibiting more severe infection symptoms and different degrees of changes in the expression of the pathogenesis-related(PR)*** addition,we showed that the endogenous jasmonic acid(JA)content of *** was increased in response to *** infection,whereas the salicylic acid(SA)content *** PlWRKY65 gene silencing,the levels of the two hormones changed accordingly,indicating that PlWRKY65,acting as a disease resistance-related transcriptional activator,exerts a regulatory effect on JA and SA *** study lays the foundation for functional research on WRKY genes in *** and for the discovery of candidate disease resistance genes.

关键词： genes resistance VIGS

Oil Content and Nervonic Acid Content of Acer truncatum Seeds from 14 Regions in China

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Horticultural Plant Journal 2019年第1期5卷 24-30页

作者： qian qiao Xue Wang Hongjian Ren Kai An Zhen Feng Tiantian Cheng Zhongkui Sun College of Forestry Shandong Agricultural University Shandong Institute of Pomology Taishan Forestry Science Institute Tai'an Shidai Technology Development Limited Company

Acer truncatum is considered a promising species as a raw material to produce nervonic acid(NA). The goal of this study was to explore the variation of oil content and nervonic acid content of 138 accessions native to 14 regions in China as well as provide guidance for establishing plantations and improving the production of nervonic acid. A large range of variation was found in oil content, nervonic acid per gram of oil, and nervonic acid per gram of seed(17.81%–36.56%, 3.90%–7.85%, and 0.84%–2.31%, respectively). Accessions YS-6, ABZ-6 and DQTL-8 were found as the most promising potential oil sources; PQ-2 was considered the optimal germplasm, and JY-6, NJ-8, LF-6, and CC-8 were found as promising potential sources for producing NA. A very significant difference(P < 0.01) among 14 regions was observed. DQTL and YS regions are considered the optimal farming regions for crops with high oil content, while the CC and PQ regions are regarded as the most suitable regions for nervonic acid production. A geographical trend from South to North was observed in which amount of seed oil increased but no such trend in nervonic acid content was observed. The data collected in the study on oil content and nervonic acid in accessions of A. truncatum in various regions can be utilized for establishing plantations of promising genotypes through clonal means.

关键词： Acer truncatum Seed oil content Nervonic acid Variation

Signaling network controlling ROP-mediated tip growth in Arabidopsis and beyond

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Plant Communications 2023年第1期4卷 198-208页

作者： En Li Yu-Ling Zhang Zheng Qin Meng Xu qian qiao Sha Li Shan-Wei Li Yan Zhang State Key Laboratory of Crop Biology College of Life SciencesShandong Agricultural UniversityTai’anShandong 271018China College of Life Sciences Nankai UniversityTianjin 300071China

Cell polarity operates across a broad range of spatial and temporal scales and is essential for specific biological functions of polarized *** growth is a special type of polarization in which a single and unique polarization site is established and maintained,as for the growth of root hairs and pollen tubes in *** studies in past decades have demonstrated that the spatiotemporal localization and activity of Rho of Plants(ROPs),the only class of Rho GTPases in plants,are critical for tip *** are switched on or off by different factors to initiate dynamic intracellular activities,leading to tip *** studies have also uncovered several feedback modules for ROP *** this review,we summarize recent progress on ROP signaling in tip growth,focusing on molecular mechanisms that underlie the dynamic distribution and activity of ROPs in *** also highlight feedback modules that control ROPmediated tip growth and provide a perspective for building a complex ROP signaling ***,we provide an evolutionary perspective for ROP-mediated tip growth in Physcomitrella patens and during plant–rhizobia interaction.

关键词： Rho GTPases feedback polarization root hair pollen tube

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随机海浪的滤波器模型及仿真

哈尔滨工程大学学报 2022年第5期43卷 600-606页

作者：乔倩范菊上海交通大学海洋工程国家重点实验室上海200240

为了研究通过引入滤波器模型实现对随机海浪的模拟,随机海浪可用有色噪声表示。在随机运动问题中,需要引入滤波器模型对白噪声输入进行处理,从而得到符合真实海浪情况的有色噪声。本文利用ARMA过程构造滤波器模型,并探讨不同阶数的ARMA... 详细信息

为了研究通过引入滤波器模型实现对随机海浪的模拟,随机海浪可用有色噪声表示。在随机运动问题中,需要引入滤波器模型对白噪声输入进行处理,从而得到符合真实海浪情况的有色噪声。本文利用ARMA过程构造滤波器模型,并探讨不同阶数的ARMA滤波器模型对ITTC双参数谱的拟合程度。通过滤波器生成谱产生波浪时历,将模拟数据的统计值与ITTC双参数谱的理论值进行对比,验证滤波器的有效性。实验结果表明:滤波器模型为随机海浪的模拟与有色干扰的变化带来了极大方便。

关键词：随机海浪海浪谱白噪声有色噪声 ARMA模型滤波器仿真

Lei Zu and Can Cong Weaved the Splendid Brocade and the Belt and Road Is Writing a Brilliant Chapter——The Chengdu Consensus of the Academic Seminar on the Land of Abundance and the Silk Road

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Contemporary Social Sciences 2017年第3期2卷 45-49页

作者： Li Mingquan qiao qian Sichuan Academy of Social Sciences

'Dawn sees saturated reds;the town’s heavy with blooms.'We,more than 90 experts and scholars from home and abroad,attended The Academic Seminar on the Land of Abundance and the Silk Road held by the Association of Chinese Historians,the Guangming Daily Press,the Society for Chinese Archaeology,the Chinese Society on Ancient Capitals,the School of Archaeology and Museology of Peking University,and Sichuan Academy of

关键词： In The Chengdu Consensus of the Academic Seminar on the Land of Abundance and the Silk Road Lei Zu and Can Cong Weaved the Splendid Brocade and the Belt and Road Is Writing a Brilliant Chapter