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High Efficiency Multi-kW Diode-Side-Pumped Nd：YAG Laser with Reduced Thermal Effect

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Chinese Physics Letters 2010年第2期27卷 83-85页

作者：徐一汀许家林崔前进谢仕永鲁远甫薄勇彭钦军崔大复许祖彦 Laboratory of Optical Physics Institute of Physics Chinese Academy of Sciences Beijing 100190 RCLPT Key Lab of Functional Crystal and Laser Technology Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 Graduate School of the Chinese Academy of Sciences Beijing 100049

We demonstrate a high efficiency multi-kW diode-side-pumped Nd：YAG laser. High cooling efficiency of the diode-side-pumped module in the laser is achieved. The middle portion of the Nd：YAG rod in the module is cooled by a coolant jet with screwed side surface, and the end-caps of the rod without screwed side surface are cooled by Au coated on the surface. The thermal effect of the laser rod is reduced, which leads to high output power with high optical-optical conversion efficiency. By using three identical Nd：YAG laser modules, an output power of 4.2 kW and beam quality of 58 mm＆#12539;mrad with an optical-optical efficiency of 35% at 1064 nm is obtained in a laser oscillator. By using four identical Nd：YAG laser modules, an output power of 3.1 kW and beam quality of 17 mm＆#12539;mrad with an optical-optical efficiency of 25.8% is demonstrated in a master oscillator power-amplifier system.

关键词： Optics quantum optics and lasers

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在职消费与制造业高质量发展

税务与经济 2024年第1期 82-96页

作者：钱翠翠郭孝菊安徽大学学报编辑部安徽合肥230039 安徽大学商学院安徽合肥230601

管理层利用在职消费从事非生产性的寻租活动已对制造业企业高质量发展产生重要影响。基于2010~2019年中国资本市场A股制造业上市公司样本,实证考察在职消费如何作用于企业高质量发展。研究发现,在职消费阻碍了企业高质量发展。机制检验... 详细信息

管理层利用在职消费从事非生产性的寻租活动已对制造业企业高质量发展产生重要影响。基于2010~2019年中国资本市场A股制造业上市公司样本,实证考察在职消费如何作用于企业高质量发展。研究发现,在职消费阻碍了企业高质量发展。机制检验表明,在职消费降低了投资效率和管理效率,进而抑制了企业高质量发展。进一步研究表明,相较于非国有企业,在职消费对企业高质量发展的抑制作用在国有企业中显著增强,产品市场竞争弱化了在职消费对企业高质量发展的不利影响。企业应通过多种激励制度安排的整合协同效应满足管理层的多样化需求,促使管理层积极履行职责,加强对管理层寻租行为的监管,减少滥用在职消费的行为,为企业高质量发展提供持续性的动力。

关键词：在职消费高质量发展投资效率管理效率

Bloodletting Cupping Therapy for postherpetic neuralgia:a systematic review and meta-analysis

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Medical Data Mining 2018年第2期1卷 57-67页

作者： qian cui Yu-Hui Ma Xiao-Ming Jin Lin-Feng Li Guo-Wei Zhang College of Chinese Medicine Hebei UniversityBaoding071002China

Objective:To evaluate the clinical effects of bloodletting cupping therapy(BCT)for patients with postherpetic ***:We comprehensively searched four Chinese databases(Wanfang,China National Knowledge Infrastructure,VIP Database for Chinese Technical Periodicals,China Biology Medicine disc)and foreign databases(Pubmed,Cochrane Library).The retrieval time was from the build-up time to May *** 5.3 software was used for statistical ***:We finally obtained 18 eligible *** with routine western medicine,BCT can significantly improve PHN(OR=7.45,95%CI,3.36-16.51,Z=4.95,P<0.01).BCT plus other methods of acupuncture with fire needle and filiform needle has significant therapeutic effect(OR=5.54,95%CI,3.01-10.19,P<0.01),BCT plus routine western medicine has significant therapeutic effect(OR=4.99,95%CI,2.73-9.11,P<0.00001).Conclusion:It showed that the therapeutic effects of BCT,BCT plus other acupuncture methods with fire needle and filiform needle,and BCT combined with western medicine are better than those treated with single western *** is effective to treat postherpetic neuralgia with Bloodletting Cupping Therapy.

关键词： Bloodletting cupping therapy Postherpetic neuralgia System evaluation Acupuncture

Mechanism analysis of Traditional Chinese Medicine in treatment of Diabetic Nephropathy based on network pharmacology and Traditional Chinese Medicine inheritance support system

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TMR Modern Herbal Medicine 2019年第2期2卷 64-73页

作者： Yu-hui Ma Li-na Zhang qian cui Lin-feng Li Guo-wei Zhang College of Chinese Medicine Hebei University Baoding Hebei China

Diabetic nephropathy is one of the most serious complications of diabetes mellitus. In the early stage, edema and proteinuria are the main clinical manifestations. In the later stage, glomerulosclerosis and interstitial fibrosis will occur. And the prognosis is poor. Nowadays, traditional Chinese medicine has a remarkable curative effect in the treatment of diabetic nephropathy. There are more and more studies on the treatment of diabetic nephropathy with traditional Chinese medicine, but most of them focus on the syndromes of diabetic nephropathy, which are short of in-depth research and summary on the mechanism of Chinese herbal prescriptions. In this paper, the traditional Chinese medicine inheritance support system and network pharmacology BATMAN-TCM software were used to collect and analyze the relevant literature. It was found that the core compatibility of Shanzhuyu, Fuling and Shuyu in the treatment of diabetic nephropathy is closely related to the signal transduction pathway and target of diabetic nephropathy, and has a positive effect on the improvement of clinical symptoms such as proteinuria, glycometabolism disorder, edema, etc. This paper explores the core compatibility of Shanzhuyu, Fuling and Shuyu on diabetic nephropathy, in order to provide reference for clinical treatment.

关键词： diabetic nephropathy traditional Chinese medicine (TCM) network pharmacology TCM inheritance support system BATMAN-TCM

The effect of music therapy on rehabilitation of children with cerebral palsy: a meta-analysis

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TMR Integrative Medicine 2019年第14期3卷 1-9页

作者： Yu-Hui Ma Li-Na Zhang qian cui Xiao-Ming Jin Guo-Wei Zhang College of Chinese Medicine Hebei University Baoding Hebei Province China

Objective: To evaluate the ctinicat efficacy of music therapy in the treatment of children with cerebrat patsy by systematic review and meta-anatysis. Methods: A comprehensive search of China Knowledge Network, Wan fang, VIP database and foreign databases PubMed and Cochrane Library was conducted from the setup of database to March 2019. After reading and screening them carefully, 14 qualified literates were got. Then extracted relevant data, and evaluated the quality and risk bias with Revman5.3.3 software. Results: There is no significant difference between music therapy in improving ctinostatism and the ability of rowing over (P > 0.05). However, music therapy has significant difference in improving sitting, running, and jumping movements, and it can atso relieve muscte spasm, improve muscte tension and stabilize children's emotions in the course of treatment and the P values of which were att tess than 0.05. Conclusion: The music therapy has a certain effect for the treatment of pediatric cerebrat patsy, especiatty in improving children's gross and fine motor abilities, which has a certain ctinicat guiding significance for rehabilitation of children with cerebrat patsy. Key words: Pediatric cerebrat patsy, Music therapy, Meta-anatysisy Ctinicat efficacyObjective: To evaluate the ctinicat efficacy of music therapy in the treatment of children with cerebrat patsy by systematic review and meta-anatysis. Methods: A comprehensive search of China Knowledge Network, Wan fang, VIP database and foreign databases PubMed and Cochrane Library was conducted from the setup of database to March 2019. After reading and screening them carefuLy, 14 qualified [iterates were got. Then extracted relevant data, and evaluated the quality and risk bias with Revman5.3.3 software. Results: There is no significant difference between music therapy in improving ctinostatism and the ability of rowing over (P > 0.05). However, music therapy has significant difference in improving sitting, run

关键词： Pediatric cerebrat patsy Music therapy Meta-anatysis Ctinicat efficacy

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基于行为语言的智能交互代理

吉林大学学报（工学版） 2018年第5期48卷 1578-1585页

作者：顾海军田雅倩崔莹吉林大学通信工程学院长春130012

提出了基于行为语言的智能交互代理,利用关键词匹配技术获取用户需求关键信息,触发cplus2asp系统根据行为语言描述的知识及规则进行推理得出调控策略,实现智能人机交互。该智能交互代理的实现方法解决了传统智能交互引擎交互接口不友好... 详细信息

提出了基于行为语言的智能交互代理,利用关键词匹配技术获取用户需求关键信息,触发cplus2asp系统根据行为语言描述的知识及规则进行推理得出调控策略,实现智能人机交互。该智能交互代理的实现方法解决了传统智能交互引擎交互接口不友好、交互过程复杂等问题的局限性。实验结果验证了该方法的有效性。

关键词：人工智能智能交互代理行为语言知识框架关键词匹配

The Credibility Estimators under MLINEX Loss Function

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Chinese Quarterly Journal of Mathematics 2018年第1期33卷 43-50页

作者： ZHANG qiang cui qian-qian CHEN Ping School of Science Nanjing University of Science and Technology Nanjing 210094 China

In this paper, MLINEX loss function was considered to solve the problem of high premium in credibility models. The Bayes premium and credibility premium were obtained under MLINEX loss function by using a symmetric quadratic loss function. A credibility model with multiple contracts was established and the corresponding credibility estimator was derived under MLINEX loss function. For this model the estimations of the structure parameters and a numerical example were also given.

关键词： MLINEX loss function Bayes premium Credibility estimator Multiple contracts

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消疹饮治疗湿疹临床疗效观察

中国临床药理学与治疗学 2015年第11期50卷 1293-1295页

作者：崔静崔前平上海华山医院急诊科上海200136 皖南医学院弋矶山医院中医科

目的:观察经验方消疹饮治疗湿疹的临床疗效及安全性。方法:将160例湿疹患者随机分为2组(n=80),治疗组给予消疹饮内服及外用敷洗;对照组给予抗组胺药马来酸氯本那敏(扑尔敏)内服及外涂糖皮质激素丁酸氢化考的松乳膏(龙卓尔)。结果:治疗... 详细信息

目的:观察经验方消疹饮治疗湿疹的临床疗效及安全性。方法:将160例湿疹患者随机分为2组(n=80),治疗组给予消疹饮内服及外用敷洗;对照组给予抗组胺药马来酸氯本那敏(扑尔敏)内服及外涂糖皮质激素丁酸氢化考的松乳膏(龙卓尔)。结果:治疗组总有效率显著优于对照组(97.50%vs 58.75%,P<0.05)。两组均未出现肝肾功能损害,但对照组出现嗜睡53例(66.25%)、口干51例(63.75%),而治疗组中则无此不良反应(P<0.01)。结论:消疹饮治疗湿疹疗效满意,且安全性高。

关键词：消疹饮湿疹风湿热毒过敏性

A novel long-term intravenous combined with local treatment with human amnion-derived mesenchymal stem cells for a multidisciplinary rescued uremic calciphylaxis patient and the underlying mechanism

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Journal of Molecular Cell Biology 2022年第2期14卷 56-71页

作者： Lianju Qin Jing Zhang Yujie Xiao Kang Liu Yugui cui Fangyan Xu Wenkai Ren Yanggang Yuan Chunyan Jiang Song Ning Xiaoxue Ye Ming Zeng Hanyang qian Anning Bian Fan Li Guang Yang Shaowen Tang Zhihong Zhang Juncheng Dai Jing Guo qiang Wang Bin Sun Yifei Ge Chun Ouyang Xueqiang Xu Jing Wang Yaoyu Huang Hongqing cui Jing Zhou Meilian Wang Zhonglan Su Yan Lu Di Wu Jingping Shi Wei Liu Li Dong Yinbing Pan Baiqiao Zhao Ying cui Xueyan Gao Zhanhui Gao Xiang Ma Aiqin Chen Jie Wang Meng Cao qian cui Li Chen Feng Chen Youjia Yu qiang Ji Zhiwei Zhang Mufeng Gu Xiaojun Zhuang Xiaolin Lv Hui Wang Yanyan Pan Ling Wang Xianrong Xu Jing Zhao Xiuqin Wang cuiping Liu Ningxia Liang Changying Xing Jiayin Liu Ningning Wang State Key Laboratory of Reproductive Medicine Center of Clinical Reproductive MedicineThe First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjing 210029China Department of Nephrology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjing 210029China Department of Epidemiology and Biostatistics School of Public HealthNanjing Medical UniversityNanjing 211166China Department of Pathology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjing 210029China Department of Cardiology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjing 210029China Department of Rheumatology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjing 210029China Department of Obstetrics The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjing 210029China Department of Dermatology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjing 210029China Department of Burn and Plastic Surgery The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjing 210029China Department of Nuclear Medicine The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjing 210029China Department of Infection The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjing 210029China Department of Anesthesiology and Pain Management The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjing 210029China Department of Nephrology The First People’s Hospital of LianyungangLianyungang 222061China Department of Nephrology Northern Jiangsu People’s HospitalYangzhou 225001China Department of General Medicine Geriatric Hospital of Nanjing Medical UniversityNanjing 210024China Department of Nephrology BenQ Medical CenterThe Affiliated BenQ Hospital of Nanjing Medical Uni

Calciphylaxis is a rare disease characterized histologically by microvessel calcification and microthrombosis,with high mortality and no proven ***,we reported a severe uremic calciphylaxis patient with progressive skin ischemia,large areas of painful malodorous ulcers,and mummified *** of the worsening symptoms and signs refractory to conventional therapies,treatment with human amnion-derived mesenchymal stem cells(hAMSCs)was *** release inspections of hAMSCs,efficacy,and safety assessment,including cytokine secretory ability,immunocompetence,tumorigenicity,and genetics analysis in vitro,were *** further performed acute and long-term hAMSC toxicity evaluations in C57BL/6 mice and rats,abnormal immune response tests in C57BL/6 mice,and tumorigenicity tests in neonatal Balbc-nu nude *** the preclinical research,the patient was treated with hAMSCs by intravenous and local intramuscular injection and external supernatant application to the *** followed up to 15 months,the blood-based markers of bone and mineral metabolism improved,with skin soft tissue regeneration and a more favorable profile of peripheral blood mononuclear *** biopsy after 1-month treatment showed vascular regeneration with mature noncalcified vessels within the dermis,and 20 months later,the re-epithelialization restored the integrity of the damaged *** infusion or local treatment-related adverse events ***,this novel long-term intravenous combined with local treatment with hAMSCs warrants further investigation as a potential regenerative treatment for uremic calciphylaxis due to effects of inhibiting vascular calcification,stimulating angiogenesis and myogenesis,anti-inflammatory and immune modulation,multidifferentiation,re-epithelialization,and restoration of integrity.

关键词： calciphylaxis chronic kidney disease vascular calcification multidisciplinary rescue human amnion-derived mesenchymal stem cells preclinical research regenerative medicine