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O-FIB:far-field-induced near-field breakdown for direct nanowriting in an atmospheric environment

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Light(Science & Applications) 2020年第1期9卷 1624-1630页

作者： Zhen-Ze Li Lei Wang Hua Fan Yan-Hao Yu qi-dai chen Saulius Juodkazis Hong-Bo Sun State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012China Nanotechnology Facility Swinburne University of TechnologyJohn St.Hawthorn 3122 VicAustralia State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision InstrumentTsinghua UniversityBeijing 100084China

Nanoscale surface texturing,drilling,cutting,and spatial sculpturing,which are essential for applications,including thin-film solar cells,photonic chips,antireflection,wettability,and friction drag reduction,require not only high accuracy in material processing,but also the capability of manufacturing in an atmospheric *** used focused ion beam(FIB)technology offers nanoscale precision,but is limited by the vacuum-working conditions;therefore,it is not applicable to industrial-scale samples such as ship hulls or biomaterials,e.g.,cells and ***,we report an optical far-field-induced near-field breakdown(O-FIB)approach as an optical version of the conventional FIB technique,which allows direct nanowriting in *** writing is initiated from nanoholes created by femtosecondlaser-induced multiphoton absorption,and its cutting“knife edge”is sharpened by the far-field-regulated enhancement of the optical near field.A spatial resolution of less than 20 nm(λ/40,withλbeing the light wavelength)is readily achieved.O-FIB is empowered by the utilization of simple polarization control of the incident light to steer the nanogroove writing along the designed *** universality of near-field enhancement and localization makes O-FIB applicable to various materials,and enables a large-area printing mode that is superior to conventional FIB processing.

关键词： field printing friction

Ultrafast optical spectroscopy of surface-modified silicon quantum dots: unraveling the underlying mechanism of the ultrabright and color-tunable photoluminescence

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Light(Science & Applications) 2015年第1期4卷 524-531页

作者： Lei Wang qi Li Hai-Yu Wang Jing-Chun Huang Ran Zhang qi-dai chen Huai-Liang Xu Wei Han Zheng-Zhong Shao Hong-Bo Sun State Key Laboratory on Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012China College of Physics Jilin UniversityChangchun 130012China State Key Laboratory of Molecular Engineering of Polymers Advanced Material LaboratoryDepartment of Macromolecular ScienceFudan UniversityShanghai 200433China

In this work,the fundamental mechanism of ultrabright fluorescence from surface-modified colloidal silicon quantum dots is investigated in depth using ultrafast *** underlying energy band structure corresponding to such highly efficient direct bandgap-like emissions in our surface-modified silicon quantum dots is unraveled by analyzing the transient optical spectrum,which demonstrates the significant effect of surface molecular *** is observed that special surface modification,which creates novel surface states,is responsible for the different emission wavelengths and the significant improvement in the photoluminescence quantum *** this essential understanding,surface-modified silicon quantum dots with deep blue to orange emission are successfully prepared without changing their sizes.

关键词： quantum confinement silicon quantum dots surface molecular engineering ultrafast spectroscopy wave function modification

Fangji Fuling Decoction Alleviates Sepsis by Blocking MAPK14/FOXO3A Signaling Pathway

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Chinese Journal of Integrative Medicine 2024年第3期30卷 230-242页

作者： WANG Yi chen Ming-qi dai Lin-feng ZHANG Hai-dong WANG Xing Department of Critical Care Medicine Changzhou Hospital of Traditional of Chinese Medicine Affiliated to Nanjing University of Chinese MedicineChangzhouJiangsu Province213000China Department of Critical Care Medicine Jiangsu Province Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese MedicineNanjing210029China

Objective:To examine the therapeutic effect of Fangji Fuling Decoction(FFD) on sepsis through network pharmacological analysis combined with in vitro and in vivo ***:A sepsis mouse model was constructed through intraperitoneal injection of 20 mg/kg lipopolysaccharide(LPS).RAW264.7 cells were stimulated by 250 ng/m L LPS to establish an in vitro cell *** pharmacology analysis identified the key molecular pathway associated with FFD in *** ectopic expression and depletion experiments,the effect of FFD on multiple organ damage in septic mice,as well as on cell proliferation and apoptosis in relation to the mitogen-activated protein kinase 14/Forkhead Box O 3A(MAPK14/FOXO3A) signaling pathway,was ***:FFD reduced organ damage and inflammation in LPS-induced septic mice and suppressed LPS-induced macrophage apoptosis and inflammation in vitro(P<0.05).Network pharmacology analysis showed that FFD could regulate the MAPK14/FOXO signaling pathway during *** confirmed by in vitro cell experiments,FFD inhibited the MAPK14 signaling pathway or FOXO3A expression to relieve LPS-induced macrophage apoptosis and inflammation(P<0.05).Furthermore,FFD inhibited the MAPK14/FOXO3A signaling pathway to inhibit LPS-induced macrophage apoptosis in the lung tissue of septic mice(P<0.05).Conclusion:FFD could ameliorate the LPS-induced inflammatory response in septic mice by inhibiting the MAPK14/FOXO3A signaling pathway.

关键词： sepsis Fangji Fuling Decoction mitogen-activated protein kinase 14/Forkhead Box O 3A signaling pathway inflammatory response apoptosis lung injury Chinese medicine

Holographic laser fabrication of 3D artificial compound μ-eyes

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Light(Advanced Manufacturing) 2023年第4期4卷 1-9页

作者： Lei Wang Wei Gong Xiao-Wen Cao Yan-Hao Yu Saulius Juodkazis qi-dai chen Jilin University State Key Laboratory of Integrated OptoelectronicsCollege of Electronic Science and EngineeringChangchun130012China Optical Sciences Centre and ARC Training Centre in Surface Engineering for Advanced Materials(SEAM) School of ScienceSwinburne University of TechnologyHawthornVictoria 3122Australia Melbourne Centre for Nanofabrication 151 Wellington RoadClayton VIC3168Australia

The demand for fast optical image acquisition without movable optical elements(e.g.,for self-driving car technology)can be met using bioinspired 3D compound eyes.3D laser processing strategies enable designable 3D structuring but suffer from low fabrication efficiency,which significantly limits their applications in producing complex 3D optical ***,we demonstrate a versatile yet simple wet-etching-assisted holographic laser fabrication method for the development of 3D compound *** compoundμ-eyes can be readily fabricated by programming a 3D spot array for the parallel ablation of a curved fused silica surface,followed by controllable etching in a hydrofluoric(HF)acid solution.A 3D-concave-lens array made on a curved surface over an area of 100μm cross-section with each lenslet of 10μm radius was fabricated with high fidelity and excellent imaging/focusing *** resultant 3D-concave-lens can serve as a hard template for the mass production of soft compound eyes through soft ***,using a generative adversarial network(GAN)-based deep learning algorithm,image restoration was conducted for each lenslet,which retained a large field of view and significantly improved image *** method provides a simple solution to the requirements of compoundμ-eyes required by Industry 4.0.

关键词： Holographic laser fabrication Wet etching compound eye Micro-optics Fast imaging Imaging restoration

Investigation of fluorescence resonance energy transfer ultrafast dynamics in electrostatically repulsed and attracted exciton-plasmon systems

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Chinese Physics B 2021年第2期30卷 529-534页

作者： Hong-Yu Tu Ji-Chao cheng Gen-Cai Pan Lu Han Bin Duan Hai-Yu Wang qi-dai chen Shu-Ping Xu Zhen-Wen dai Ling-Yun Pan State Key Laboratory of Superhard Materials College of PhysicsJilin UniversityChangchun 130012China State Key Laboratory on Integrated Optoelectronics College of ElectronicsScience and EngineeringJilin UniversityChangchun 130012China State Key Laboratory of Supramolecular Structure and Materials Jilin UniversityChangchun 130012China

Following the gradual maturation of synthetic techniques for nanomaterials,exciton-plasmon composites have become a research hot-spot due to their controllable energy transfer through electromagnetic fields on the ***,most reports ignore fluorescence resonance energy transfer(FRET)under electrostatic repulsion *** this study,the FRET process is investigated in both electrostatic attraction and electrostatic repulsion *** changing the Au:quantum dot ratio,local-field induced FRET can be observed with a lifetime of ns and a fast component of hundreds of *** results indicate that the intrinsic transfer process can only elucidated by considering both steady and transient state information.

关键词： fluorescence resonance energy transfer(FRET) quantum dots excitons-plasmon composites

On-chip single-photon chirality encircling exceptional points

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Chip 2023年第4期2卷 71-77页

作者： Zhen-Nan Tian Feng Yu Xu-Lin Zhang Kai Ming Lau Li-cheng Wang Jensen Li C.T.Chan qi-dai chen State Key Laboratory of Integrated Optoelectronics College of Electronic Sci-ence and EngineeringJilin UniversityChangchun 130012China Department of Physics The Hong Kong University of Science and TechnologyClear Water BayHong Kong 999077China

Exceptional points(EPs),which are typically defined as the degener-acy points of a non-Hermitian Hamiltonian,have been investigated in various physical systems such as photonic *** particular,the intriguing topological structures around EPs have given rise to novel strategies for manipulating photons and the underlying mechanism is especially useful for on-chip photonic *** some on-chip experiments with the adoption of lasers have been reported,EP-based photonic chips working in the quantum regime largely re-main *** the current work,a single-photon experiment was proposed to dynamically encircle an EP in on-chip photonic waveg-uides possessing passive anti-parity-time *** coinci-dences measurement reveals a chiral feature of transporting single photons,which can act as a building block for on-chip quantum de-vices that require asymmetric *** findings in the cur-rent work pave the way for on-chip experimental study on the physics of EPs as well as inspiring applications for on-chip non-Hermitian quantum devices.

关键词： Non-Hermitian photonics Photonic chip Exceptional points Single photons

Perioperative and long-term results of ultrasonography-guided single-and multiple-tract percutaneous nephrolithotomy for staghorn calculi

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World Journal of Clinical Cases 2024年第7期12卷 1243-1250页

作者： Rui-Xiang cheng Ni dai Yan-Min Wang Pei qi Fen chen Department of Urology Wuhan Ninth HospitalWuhan 430081Hubei ProvinceChina Department of Urinary Pain Wuhan Hankou HospitalWuhan 430000Hubei ProvinceChina Pre-hospital Emergency Department Wuhan Puren HospitalWuhan 430081Hubei ProvinceChina Department of Orthopedic Trauma Surgery Wuhan Hankou HospitalWuhan 430000Hubei ProvinceChina Department of Ultrasound Hubei Provincial Hospital of Integrated Traditional Chinese and Western MedicineWuhan 430015Hubei ProvinceChina

BACKGROUND It is possible that this condition will lead to urosepsis and progressive deterioration of renal function in the absence of surgical *** recent clinical studies have shown that multi-tract percutaneous nephrolithotomy(MPCNL)has a similar stone free rate(SFR)as standard percutaneous nephrolithotomy(S-PCNL).As a result,M-PCNL was also recommended as a treatment option for staghorn *** To examine the perioperative and long-term results of ultrasonography-guided single-and *** This was a retrospective cohort *** March 2021 and January 2022,the urology department of our hospital selected patients for the treatment of staghorn calculi using percutaneous *** primary outcomes were com plication rate and SFR,and the characteristics of patients,operative parameters,laboratory measurements were also *** In total,345 patients were enrolled in the study(186 in the S-PCNL group and 159 in the M-PCNL group).The SFR in the M-PCNL group was significantly higher than that in the S-PCNL group(P=0.033).Moreover,the incidence rates of hydrothorax(P=0.03)and postoperative infection(P=0.012)were higher in the M-PCNL group than in the S-PCNL *** regression analysis demonstrated that post-operative white blood cell count(OR=2.57,95%CI:1.90-3.47,P<0.001)and stone size(OR=1.59,95%CI:1.27-2.00,P<0.001)were associated with a higher overall complication rate in the S-PCNL *** mass index(OR=1.22,95%CI:1.06-1.40,P=0.004)and stone size(OR=1.70,95%CI:1.35-2.15,P<0.001)were associated with increased overall complications in the M-PCNL *** Multiple access tracts can facilitate higher SFR while slightly increasing the incidence of acceptable complications.

关键词： Single-tract percutaneous nephrolithotomy Multiple-tract percutaneous nephrolithotomy Staghorn calculi Ultrasonography

Etching‐assisted femtosecond laser modification of hard materials

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Opto-Electronic Advances 2019年第9期2卷 1-14页

作者： Xue-qing Liu Ben-Feng Bai qi-dai chen Hong-Bo Sun State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision InstrumentTsinghua UniversityBeijing 100084China State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012China

With high hardness, high thermal and chemical stability and excellent optical performance, hard materials exhibit great potential applications in various fields, especially in harsh conditions. Femtosecond laser ablation has the capability to fabricate three-dimensional micro/nanostructures in hard materials. However, the low efficiency, low precision and high surface roughness are the main stumbling blocks for femtosecond laser processing of hard materials. So far, etching- assisted femtosecond laser modification has demonstrated to be the efficient strategy to solve the above problems when processing hard materials, including wet etching and dry etching. In this review, femtosecond laser modification that would influence the etching selectivity is introduced. The fundamental and recent applications of the two kinds of etching assisted femtosecond laser modification technologies are summarized. In addition, the challenges and application prospects of these technologies are discussed.

关键词： femtosecond laser hard materials wet etching dry etching

Evaluation of 3D crustal seismic velocity models in southwest China:Model performance,limitation,and prospects

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Science China Earth Sciences 2024年第2期67卷 604-619页

作者： Xin WANG Ling chen qi-Fu chen Key Laboratory of Earth and Planetary Physics Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing100049China State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China

Southwest China is a tectonically and seismically active region,witnessing strong deformation due to the collision between the Indian and Eurasian *** the subsurface velocity structure of this region is thus important in understanding the tectonics and geodynamic processes of continental collision and in mitigating seismic *** studies have provided various 3D seismic velocity models in southwest ***,discrepancies exist among these models,and less effort has been made to quantify the reliability and accuracy of these existing velocity *** this study,we use regional 3D waveform simulation to evaluate the performance of various regional crustal 3D velocity models in reproducing observed *** particularly focus on two recent earthquake sequence in the region,the 2021 Yunnan Yangbi MS_(6.4) earthquake sequence and the 2022 Sichuan Luding MS_(6.8) earthquake *** tested 3D velocity models include the Southwest China Community Velocity model V1.0,the Unified Seismic Tomography Models for Continental China Lithosphere V2.0,the adjoint full waveform tomography model of the crustal and upper mantle beneath Eastern Tibetan Plateau,and the shallow seismic structure model beneath continental *** results show that the tested 3D velocity models generally capture well long-period(<0.2 Hz)waveforms,indicating that the 3D models adequately resolve overall large-scale subsurface ***,the 3D synthetics show discrepancies in higher frequencies(0.05–0.3 Hz)and the performance of the 3D velocity models varies from region to region,suggesting that smaller scale heterogeneities are not well *** shallow velocity structures(<10 km)can improve the waveform fitting,emphasizing the importance of incorporating shallow structures in waveform *** full-waveform tomography model shows a slighter better performance than the other models,especially for the body-waves,highlighting the advantages

关键词： Southwest China Seismic tomography models Shallow Structures Waveform simulation Model evaluation