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China’s foreign direct investment in BRICS countries:status,problems and prospects

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China Finance and Economic Review 2014年第1期3卷 70-82页

作者： Sang Bai-chuan Zheng Wei Tan Hui ai qi University of International Business and Economics BeijingChina University of London LondonUnited Kingdom

The emerging economies,represented by the BRICS,have risen rapidly in post-crisis era in both economic development and national *** order to ensure a stable and sustainable long-term development of national economy,the governments of BRICS countries have shown positive attitude to foreign direct *** is a great opportunity for China to increase its direct investment in these countries,which will not only provide strong support to China’s“going global”strategy,but also help avoid risks arising from intensive investment in its traditional investment *** article focuses on the status of Chinese outward direct investment in the BRICS countries by analyzing existing problems in investment process and providing forecast as well as future agenda on China’s direct investment in these countries.

关键词： China BRICS countries outward foreign direct investment

Determination of Amino Acids in Panax notoginseng by Microwave Hydrolysis and Derivatization Coupled with Capillary Zone Electrophoresis Detection

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Chemical Research in Chinese Universities 2013年第3期29卷 434-438页

作者： LI Xiao-tian ZHAO Ya-jing JIANG Cheng-fei ZHANG Han-qi YU ai-min College of Chemistry Jilin University Changehun 130012 P. R. China

The microwave hydrolysis and derivatization coupled with capillary electrophoresis detection were developed for the separation and determination of the amino acids in Panax notoginseng. The experimental conditions for the microwave hydrolysis and derivatization were examined and optimized. Several parameters of capillary electrophoresis, such as pH value of background electrolyte, borate concentration and applied voltage were optimized Under the selected conditions, 11 amino acids were completely separated. The real sample was analyzed and the results were satisfactory. Compared with that of conventional heat hydrolysis and derivatization, the analytical time of this method was significantly shortened.

关键词： Microwave hydrolysis Derivatization Amino acid Capillary electrophoresis Panax notoginseng 2,4-Dinitrofluorobenene

A dual-switching spin-crossover framework with redox regulation and guest response

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Science China Chemistry 2023年第6期66卷 1744-1749页

作者： Long-Fei Wang Si-Guo Wu Ze-Yu Ruan ai-qi Jian Wen Cui Zhao-Ping Ni Ming-Liang Tong Key Laboratory of Bioinorganic and Synthetic Chemistry of Ministry of Education School of ChemistrySun Yat-Sen UniversityGuangzhou 510275China CNRS Centre de Recherche Paul PascalPessac F-33600France

A dual-switching spin crossover metal-organic framework(SCO-MOF)[Fe(TPB){Pt^(Ⅱ)(CN)_(4)}]·3iPrOH·4H_(2)O(TPB=1,2,4,5-tetra(pyridin-4-yl)benzene)is developed via the combination of redox-active framework and tunable *** reversible structural transformation between[Pt^(Ⅱ)(CN)_(4)]^(2-) and[Pt^(Ⅳ)Br_(2)(CN)_(4)]^(2-)moieties can be manipulated by redox post-synthetic modification(PSM),which results in the change of SCO behaviors from step-wise to *** influences of the oxidative addition of bromides on the ligand field splitting of Fe side are further explored by density functional theory ***,the modulation of hysteretic four-/three-step,one-step and four-step SCO behaviors can be achieved by tuning the composition of guest ***,the combination of electronic bistability,redox reaction and guest recognition in a homogeneous lattice provides a utility platform for designing multi-responsive molecule-based materials.

关键词： spin crossover iron(Ⅱ) post-synthetic modification redox host-guest interaction

Mapping of QTL conferring leaf rust resistance in Chinese wheat lines W014204 and Fuyu 3 at adult plant stage

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Journal of Integrative Agriculture 2016年第1期15卷 18-28页

作者： qi ai-yong ZHANG Pei-pei ZHOU Yue YAO Zhan-jun LI Zai-feng LIU Da-qun Department of Plant Pathology College of Plant Protection Agricultural University of Hebei Department of Biochemistry Baoding University College of Agronomy Agricultural University of Hebei

Wheat leaf rust is a destructive foliar disease of common wheat （Triticum aestivum L.） worldwide. The most effective, economical s to control the disease is growing resistant cultivars with adult plant resistance （APR）. The Chinese wheat tines W014204 and Fuyu 3 showed high leaf rust resistance in the field. To identify leaf rust APR genes in the two lines, two mapping populations with 215 and 163 F2：3 lines from the crosses W014204/Zhengzhou 5389 and Fuyu 3/Zhengzhou 5389, respectively, were phenotyped for leaf rust severities during the 2010-2011, 2011-2012 and 2012-2013 cropping seasons in the field at Baoding, Hebei Province, China. A total of 1 215 SSR markers were used to identify the quantitative trait loci （QTLs） for leaf rust APR in the two populations. In the W014204/Zhengzhou 5389 population, three QTLs were detected and designated as ***-lBL.1, ***-2BS.1 and ***-7DS, and explained 2.9-8.4, 11.5-38.3 and 8.5-44.5% of the phenotypic variance, respectively; all the resistance alleles at these loci were derived from W014204. In the Fuyu 3/Zhengzhou 5389 population, three QTLs, ***-lBL.2, ***-2BS.2 and ***-7BL, explained 12.0-19.2, 22.3-38.9 and 4.1-4.3% of the phenotypic variance, respectively, and all resistance alleles were contributed by Fuyu 3. Based on chromosome positions of closely linked markers, both ***-lBL. 1 and ***-lBL.2 are Lr46, and ***-7DS is Lr34. ***-7BL was mapped on chromosome 7BL near to Lr68 and they are likely the same gene. Based on chromosome positions, pedigree and field reactions, the two 2BS QTLs are different from all the known APR genes and are likely to be newAPR QTL for leaf rust. These QTLs and their closely linked markers are potentially useful for improving leaf rust resistance in wheat breeding.

关键词： Triticum aestivum Puccinia triticina APR SSR marker

Social isolation, loneliness and subsequent risk of major adverse cardiovascular events among individuals with type 2 diabetes mellitus

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General Psychiatry 2023年第6期36卷 481-490页

作者： Yannis Yan Liang Yilin Chen Hongliang Feng Huachen Xue Yu Nie qi-Yong H ai Jiacheng Ma Lulu Yang Jihui Zhang Sizhi ai Center for Sleep and Circadian Medicine The Affiliated Brain Hospital of Guangzhou Medical UniversityGuangzhouGuangdongChina Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China Guangzhou Medical UniversityGuangzhouGuangdongChina institute of Psycho-neuroscience The Affiliated Brain Hospital of Guangzhou Medical UniversityGuangzhouGuangdongChina Guangdong Cardiovascular Institute Guangdong Provincial People's HospitalGuangdong Academy of Medical SciencesGuangzhouGuangdongChina State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Department of Neurology and National Center for Neurological DisordersHuashan HospitalFudan UniversityShanghaiChina Department of Health Technology and Informatics The Hong Kong Polytechnic UniversityKowloonHong Kong Department of Cardiology Heart CenterThe First Affiliated Hospital of Xinxiang Medical UniversityWeihuiHenanChina

Background Individuals with type 2 diabetes mellitus(T2DM)are more vulnerable to social disconnection compared with the general population;however,there are few relevant studies investigating this *** To investigate whether social isolation or loneliness may be associated with subsequent risk of developing major adverse cardiovascular events,whether these associations vary according to fatal and non-fatal outcomes and how behavioural,psychological and physiological factors mediate these *** This longitudinal analysis included data from 19360 individuals with T2DM at baseline(2006-2010)from the UK *** isolation and loneliness were measured using self-report *** study outcomes included the first events of myocardial infarction(MI)or stroke(n=2273)and all-cause(n=2820)or cardiovascular disease-related mortality through linked hospital data ordeath *** Over a median follow-up of 12.4 years(interquartile range(IQR):11.6-13.3 years),participants who were more socially isolated(most social isolation vs least social isolation)experienced increased risks for all-cause(hazard ratio(HR):1.33,95%confidence interval(Cl):1.19 to 1.47)and cardiovascular disease(HR:1.36,95%Cl:1.17 to 1.59)mortality but not first Ml or ***(yes vs no)was associated with a greater risk for a composite of incident MI or stroke(HR:1.37,95%Cl:1.19 to 1.57)but not *** isolation was associated with fatal Ml and stroke,whereas loneliness was associated with non-fatal Ml and *** significant associations of social isolation and loneliness with outcomes were mainly mediated by behavioural factors(mediating proportion:17.8%-28.2%and 17.6%-17.8%,respectively).Conclusions Among individuals with T2DM,social isolation and loneliness are associated with a greater risk of developing major adverse cardiovascular events,with differences in both risks stratified according to fatal and non-fatal events and underlying mediat

关键词： cardiovascular mortality mellitus

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CPU空气强迫对流冷却系统设计

电子学报 2007年第8期35卷 1592-1597页

作者：周建辉杨春信 ai qi 鲁俊勇北京航空航天大学航空科学与工程学院北京100083 奇宏电子（深圳）有限公司广东深圳518104

根据空气强迫对流冷却系统一体化设计理念,对9238CPU风扇进行空气动力设计,由Fortran程序输出三维空间曲线文件,导入Pro/E实现实体造型.通过标准风洞对CNC铣床雕刻出的样品进行风扇性能测试.根据风扇数值模拟结果(风扇出口流场特性)设... 详细信息

根据空气强迫对流冷却系统一体化设计理念,对9238CPU风扇进行空气动力设计,由Fortran程序输出三维空间曲线文件,导入Pro/E实现实体造型.通过标准风洞对CNC铣床雕刻出的样品进行风扇性能测试.根据风扇数值模拟结果(风扇出口流场特性)设计系列放射状散热器.采用分块六面体网格技术,应用多参考旋转坐标系模型和RNGk-ε模型对风扇和曲线型散热器进行整体数值模拟,模拟结果表明曲线型散热器相对传统垂直型散热器热阻值降低15.9%,最后通过实验证明数值模拟的可信性.一体化设计思想指导下的系列散热器能达到高性能散热效果.

关键词：计算流体力学熵产最小化原理一体化设计风扇曲线型散热器

土质层状地基与相应桩端持力层极限承载力差异性研究

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岩土工程学报 2007年第4期29卷 608-611页

作者：周爱其杭州市勘测设计研究院浙江杭州310012

本文研究与比较了土质地基中地基极限承载力和相应桩端持力层极限承载力两者在概念、破坏模式、假设条件等方面的不同,并基于Meyerhof极限承载力破坏模式,讨论并提出了土质层状地基极限承载力与相应桩端持力层极限承载力破坏模式;指出... 详细信息

本文研究与比较了土质地基中地基极限承载力和相应桩端持力层极限承载力两者在概念、破坏模式、假设条件等方面的不同,并基于Meyerhof极限承载力破坏模式,讨论并提出了土质层状地基极限承载力与相应桩端持力层极限承载力破坏模式;指出了两者的本质差异,并对影响极限端承力发挥的若干情况进行了讨论,得出若干结论,对具体工程勘察设计具借鉴意义。

关键词：土质层状地基 Meyerhof极限承载力破坏模式刚塑性体极限平衡条件等代自由面抗剪强度动用系数

高层隔震结构多阶振型减震机理与倾覆问题研究

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振动工程学报 2013年第4期26卷 487-492页

作者：祁皑徐翔福州大学土木工程学院福建福州350108

如何获得良好的减震效果及抵抗倾覆是隔震技术应用到高层建筑结构中必须解决的两个主要问题。通过对高层抗震与隔震结构的地震时程对比分析,验证了高层隔震建筑存在多阶振型共同减震的现象。根据多振型高宽比显式计算公式计算可知,高阶... 详细信息

如何获得良好的减震效果及抵抗倾覆是隔震技术应用到高层建筑结构中必须解决的两个主要问题。通过对高层抗震与隔震结构的地震时程对比分析,验证了高层隔震建筑存在多阶振型共同减震的现象。根据多振型高宽比显式计算公式计算可知,高阶振型对结构高宽比限值的计算有较大影响,是研究高层隔震结构抗倾覆问题不可忽略的影响因素。

关键词：高层建筑减震效果抵抗倾覆多阶振型减震高阶振型

Chidamide and sintilimab combination in diffuse large B-cell lymphoma progressing after chimeric antigen receptor T therapy

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World Journal of Clinical Cases 2022年第19期10卷 6555-6562页

作者： Yuan-Yuan Hao Pan-Pan Chen Xiang-Gui Yuan ai-qi Zhao Yun Liang Hui Liu Wen-Bin qian Department of Hematology The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina

BACKGROUND Diffuse large B-cell lymphoma(DLBCL)is curable with first-line chemoimmunotherapy but patients with relapsed/refractory(R/R)DLBCL still face a poor *** patients with R/R DLBCL,the complete response rate to traditional next-line therapy is only 7%and the median overall survival is 6.3 ***,CD19-targeting chimeric antigen receptor T cells(CAR-T)have shown promise in clinical ***,approximately 50%of patients treated with CAR-T cells ultimately progress and few salvage therapies are *** SUMMARY Here,we report on 7 patients with R/R DLBCL whose disease progressed after CAR-T *** received a PD-1 inhibitor(sintilimab)and a histone deacetylase inhibitor(chidamide).Five of the 7 patients tolerated the treatment without any serious adverse *** patients discontinued the treatment due to lung infection and *** the 20-mo follow-up,the median overall survival of these 7 patients was 6 *** note,there were 2 complete response rates(CRs)and 2 partial response rates(PRs)during this novel therapy,with an overall response rate(ORR)of 57.1%,and one patient had a durable CR that lasted at least 20 *** In conclusion,chidamide combined with sintilimab may be a choice for DLBCL patients progressing after CD19-targeting CAR-T therapy.

关键词： Chimeric antigen receptor T cell therapy Diffuse large B-cell lymphoma Immunotherapy PD-1 inhibitor Histone deacetylase inhibitor Case report