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Rice straw management through biofuel,biochar,mushroom cultivation,and paper production to overcome environmental pollution in North India

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Waste Disposal and Sustainable Energy 2023年第4期5卷 483-510页

作者： Vikram Kumar Pooja Singh Jyoti sharma Sakshi Saini priyanka sharma Asha sharma Department of Botany Maharshi Dayanand UniversityRohtakHaryana124001India

Rice is the prominent food grain required by more than half of the world's population to fulfill their nutritional *** the continuous growth in the population at the global level,rice production has also been ***,high rice production also creates a new problem in waste management *** straw,generated after rice harvest,possesses meager nutritional value,due to which it is less preferred as fodder and burned in the *** burning is one of the major causes of air pollution,leading to lung,heart,eye,and skin-related diseases and even premature *** stubble burning also decreases soil *** this review article,we have discussed the various economic uses of paddy straw which will help to reduce air pollution through the decline in paddy straw *** is produced from paddy straw,which can be mixed into the soil to restore fertility and reduce toxic metals'*** generation of biofuels such as biobutanol,bioethanol,and biogas from rice straw with their mechanism of synthesis is also discussed in this *** straw can also be utilized in the preparation of solid *** with this,mushroom cultivation in paddy straw houses is also *** straw can be used for the pulp and paper industries,which will help to reduce the tree dependence of these *** from this,a bibliometric analysis of the Scopus database on rice straw uses for the last 20 years was done,including a bibliographic keyword analysis to show published documents'*** review will give an elaborated overview of the alternative uses of rice straw with a quantitative analysis of air pollution caused by paddy straw *** review will also help to improve the current uses of paddy straw for industrial and commercial benefits to make it more economical.

关键词： Rice straw Environment pollution Biochar Biofuels Mushroom cultivation Paper and pulp

Effect of forest fire on soil microbial biomass and enzymatic activity in oak and pine forests of Uttarakhand Himalaya, India

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Ecological Processes 2021年第1期10卷 394-407页

作者： Devanshi Singh priyanka sharma Ujjwal Kumar Achlesh Daverey Kusum Arunachalam School of Environment and Natural Resources Doon UniversityDehradunUttarakhand 248012India

Background:Forest fire incidences in the Himalayan region of Uttarakhand,India are very common in *** and oak are the principal and dominant species of Himalayan subtropical forest and Himalayan temperate forest,*** vegetation influences the physicochemical and biological properties of soil and forest fire in pine and oak forests may have a different effect on the physicochemical and biological properties of ***,the present study was carried out to assess the impact of forest fire on soil microbial properties,enzymatic activity,and their relationship with soil physicochemical properties in the advent of forest fire in the pine and oak forests of the Garhwal region of Uttarakhand Himalaya,***:The soil microbial biomass carbon and nitrogen,soil basal respiration,and acid phosphatase activity decreased,whereas dehydrogenase activity increased at burnt sites of both forest *** overall change in soil microbial biomass carbon was 63 and 40%at the burnt oak forest and burnt pine forest,*** activity and acid phosphatase activity showed a strong positive correlation with soil organic matter(r=0.8)and microbial indices,*** ratio of soil microbial biomass carbon/nitrogen was reduced at burnt sites of both forest *** analysis results showed that fire had a significant impact on soil *** soil basal respiration was linked with macro-and micronutrients at burnt sites,whereas at control sites,it was linked with physicochemical properties of soil along with ***:Forest fire had a significant impact on soil properties of both forest *** impact of forest fire on soil microbial biomass carbon was stronger in the oak forest than in the pine *** type influenced soil enzymatic activity at burnt *** bacterial community was dominated over fungi in burnt sites of both *** microbial indices can be used as a selective measure to assess

关键词： Microbial indices Soil enzymes Microbial biomass Forest fire Pine forest Oak forest

Targeting metabolic vulnerabilities to overcome resistance to therapy in acute myeloid leukemia

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Cancer Drug Resistance 2023年第3期6卷 567-589页

作者： priyanka sharma Gautam Borthakur Department of Leukemia Section of Molecular Hematology and TherapeuticsThe University of Texas MD Anderson Cancer CenterHoustonTX 77030USA

Malignant hematopoietic cells gain metabolic plasticity, reorganize anabolic mechanisms to improve anabolic output and prevent oxidative damage, and bypass cell cycle checkpoints, eventually outcompeting normal hematopoietic cells. Current therapeutic strategies of acute myeloid leukemia (AML) are based on prognostic stratification that includes mutation profile as the closest surrogate to disease biology. Clinical efficacy of targeted therapies, e.g., agents targeting mutant FMS-like tyrosine kinase 3 (FLT3) and isocitrate dehydrogenase 1 or 2, are mostly limited to the presence of relevant mutations. Recent studies have not only demonstrated that specific mutations in AML create metabolic vulnerabilities but also highlighted the efficacy of targeting metabolic vulnerabilities in combination with inhibitors of these mutations. Therefore, delineating the functional relationships between genetic stratification, metabolic dependencies, and response to specific inhibitors of these vulnerabilities is crucial for identifying more effective therapeutic regimens, understanding resistance mechanisms, and identifying early response markers, ultimately improving the likelihood of cure. In addition, metabolic changes occurring in the tumor microenvironment have also been reported as therapeutic targets. The metabolic profiles of leukemia stem cells (LSCs) differ, and relapsed/refractory LSCs switch to alternative metabolic pathways, fueling oxidative phosphorylation (OXPHOS), rendering them therapeutically resistant. In this review, we discuss the role of cancer metabolic pathways that contribute to the metabolic plasticity of AML and confer resistance to standard therapy;we also highlight the latest promising developments in the field in translating these important findings to the clinic and discuss the tumor microenvironment that supports metabolic plasticity and interplay with AML cells.

关键词： OXPHOS DHODH leukemia stem cells mesenchymal stromal cells IDH

Structural characterization of carboxyl cellulose nanofibers extracted from underutilized sources

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Science China(Technological Sciences) 2019年第6期62卷 971-981页

作者： ZHAN ChengBo sharma priyanka R. GENG LiHong sharma Sunil K. WANG RuiFu JOSHI Ritika HSIAO Benjamin S. Department of Chemistry Stony Brook University Stony Brook NY 11794-3400 USA National Engineer Research Center of Novel Equipment for Polymer Processing Key Laboratory of Polymer Processing Engineering of Ministry of Education South China University of Technology Guangzhou 510640 China

Two different chemical methods, TEMPO-oxidation and nitro-oxidation, were used to extract carboxyl cellulose nanofibers(CNFs) from non-wood biomass sources(i.e., jute, soft and hard spinifex grasses). The combined TEMPO-oxidation and homogenization approach was very efficient to produce CNFs from the cellulose component of biomass;however, the nitrooxidation method was also found to be effective to extract CNFs directly from raw biomass even without mechanical *** effect of these two methods on the resulting cross-section dimensions of CNFs was investigated by solution small-angle Xray scattering(SAXS), transmission electron microscopy(TEM) and atomic force microscopy(AFM). The UV-Vis spectroscopic data from 0.1 wt% TEMPO-oxidized nanofiber(TOCNF) and nitro-oxidized nanofiber(NOCNF) suspensions showed that TOCNF had the highest transparency(> 95%) because of better dispersion, resulted from the highest carboxylate content(1.2 mmol/g). The consistent scattering and microscopic results indicated that TOCNFs from jute and spinifex grasses possessed rectangular cross-sections, while NOCNFs exhibited near square cross-sections. This study revealed that different oxidation methods can result in different degrees of biomass exfoliation and different CNF morphology.

关键词： cellulose nanofibers TEMPO-oxidation nitro-oxidation SAXS microscopy jute spinifex

Community cancer screening at primary care level in Northern India:determinants and policy implications for cancer prevention

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Family Medicine and Community Health 2023年第S1期11卷 12-22页

作者： priyanka sharma Divya Khanna Satyajit Pradhan Praveen Birur Preventive Oncology Mahamana Pandit Madan Mohan Malaviya Cancer CentreVaranasiUttar PradeshIndia Radiation Oncology Mahamana Pandit Madan Mohan Malaviya Cancer CentreVaranasiUttar PradeshIndia KLE Society's Institute of Dental Sciences BangaloreKarnatakaIndia

Objective Despite the established cancer screening programme for oral,breast and cervical cancer by the Government of India,the screening coverage remains *** study aimed to describe the determinants for oral,breast and cervical cancer prevention in a rural community at the primary care level of Northern India and its policy *** This was a camp-based project conducted for 1 year,using oral visual examination,clinical breast examination and visual inspection of cervix by application of 5%acetic acid according to primary healthcare operational *** the project,screen-positive participants were followed through reverse *** about socio-demographic profile,clinical and behavioural history and screening were *** for screen-positivity and follow-up compliance were identified through multivariable *** Based on the aim of project,one of the remotely located and low socioeconomic rural blocks,having 148 villages(estimated population of 254285)in Varanasi district,India was selected as the service *** is an established healthcare delivery and referral system as per the National Health Mission of Government of ***,breast,gallbladder and cervical cancers are the leading cancers in the *** We invited all men and women aged 30-65 years residing in the selected block for the last 6 months for the screening *** women,women with active vaginal bleeding,those currently pregnant and those who have undergone hysterectomy were excluded from cervical cancer *** A total of 14338 participants were screened through 190 camps and the majority(61.9%)were *** religion,tobacco use,intention to quit tobacco and presence of symptoms were significantly associated with *** one-third(220;30.1%)of the screened-positives complied with *** age and illiteracy were significantly associated with lower ***

关键词： prevention policy India

Multi-omics:Powerful accelerator for uncovering plant specialized metabolic pathways:The case of leonurine

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Molecular Plant 2024年第1期17卷 13-15页

作者： priyanka Gupta Anuj sharma Dinesh A.Nagegowda Molecular Plant Biology and Biotechnology Lab CSIR-Central Institute of Medicinal and Aromatic PlantsResearch CentreBengaluru 560065India Academy of Scientific and Innovative Research Ghaziabad 201002India

As sessile organisms,plants employ a unique adaptive strategy to survive harsh terrestrial environments and defend against or interact with coevolving animals and *** strategy involves expanding their metabolic systems,resulting in the production of plant specialized metabolites(PSMs)or natural ***,PSMs constitute a highly diverse group of compounds based on their common core structure,comprising terpenoids,phenylpropanoids,benzenoids,alkaloids and nitrogen-containing compounds,glucosinolates,indoles and sulfur-containing indole compounds,phenolics,and fatty acid derivatives(Garagounis et al.,2021).

关键词： expanding alkaloids sulfur

Coexistence of pneumothorax and chilaiditi sign:A case report

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Asian Pacific Journal of Tropical Biomedicine 2014年第1期4卷 75-77页

作者： Tangri Nitin Singhal Sameer sharma priyanka Mehta Dinesh Bansal Sachin Bhushan Neeraj Singla Sulbha Singh Puneet Department of Respiratory Medicine M.M Institute of Medical Sciences & Research Department of Biochemistry M.M Institute of Medical Sciences & Research

We present a case of 50 year old male patient with coexistence of Pneumothorax and Chilaiditi *** sign is an incidental radiographic finding of a usually asymptomatic condition in which a part of intestine is located between the liver and diaphragm;however,the term"Chilaiditi syndrome"is used for symptomatic hepatodiaphragmatic *** patient had no symptoms of abdominal pain,constipation,diarrhea,or ***,Chilaiditi sign was diagnosed on chest *** is defined as air in the pleural *** are classified as spontaneous or *** pneumothorax is labelled as primary when no underlying lung disease is present,or secondary,when it is associated with pre-existing lung *** case is the rare in the literature indicating the coexistence of Chilaiditi sign and pneumothorax.

关键词： Chilaiditi syndrome Chilaiditi’s sign Hepatodiaphragmatic interposition Pneumothorax Dyspnoea Chest pain

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云原生和微服务

软件和集成电路 2020年第8期 50-51页

作者： priyanka sharma 云原生基金会

我与云原生渊源颇深,之前,我是CNCF的董事会成员,所以我深知这个基金会有很大的影响力。CNCF创立于2015年12月,是一个非营利性组织,是Linux基金会的一部分,我们的目标是为云原生软件构建可持续的生态系统。CNCF托管了很多关键任务技术... 详细信息

我与云原生渊源颇深,之前,我是CNCF的董事会成员,所以我深知这个基金会有很大的影响力。CNCF创立于2015年12月,是一个非营利性组织,是Linux基金会的一部分,我们的目标是为云原生软件构建可持续的生态系统。CNCF托管了很多关键任务技术和底层的基础架构,因此,成百上千的开发者、供应商及用户走到了一起。

关键词：基础架构非营利性组织 Linux 生态系统微服务 CNC 软件构建开发者

Mutualistic Interaction of Piriformospora indica(Serendipita indica) with Aloe vera, the Wonder Plant for Modern Living

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American Journal of Plant Sciences 2019年第11期10卷 2002-2011页

作者： Neeraj Shrivastava Shubhangi Mahajan Aditi Jain priyanka sharma Amit C. Kharakwal Ajit Varma Amity Institute of Microbial Technology (AIMT) Amity University Uttar Pradesh Noida India

Aloe vera, a short-stemmed shrub is described as a “wonder plant”, due to its vast uses in various medical products. Since many decades, extensive research has revealed that the pharmacological active ingredients are distributed in both the gel and rind of the Aloe vera leaves. A. vera is very popular in cosmetic and pharmaceutical industries and it is needed in large quantities with higher fractions of important constituents. To satisfy the market demand, intervention of microbial community seems to be a promising approach, which helps to increase the growth and metabolites along with plant fitness. Piriformospora indica is a root colonizing endophytic fungus, having unique plant growth-promoting properties. It helps the plant to acquire more nutrients from soil even under extreme physical and nutrient stress conditions. It interacts with a wide range of hosts. Interaction of P. indica with A. vera resulted in overall increase in plant biomass and greater shoot and root length, as well as number of shoots and roots as compared to control under both in vitro and in vivo environment conditions. Apart from that, the photosynthetic pigments (Chl a, Chl b and total Chl) and aloin content were observed significantly higher in A. vera plantlets colonized with symbiotic endophyte. The antioxidant activities were also tested and found significantly higher as compared to control plants. This imparts the potential of P. indica, to resist the plants against phyto-pathogenic microbes. P. indica has been proved as a potential candidate to enhance the biomass production along with various value additions in the form of active ingredients in A. vera.

关键词： Aloe vera Piriformospora indica Aloe Gel Secondary Metabolites