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A comprehensive review on pharmacognosy, phytochemistry and pharmacological activities of 8 potent Prunus species of southeast Asia

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Journal of Traditional Chinese Medicine 2024年第3期44卷 620-628页

作者： Shikha Agrawal Adarsh kumar Ankit kumar singh Harshwardhan singh Suresh Thareja pradeep kumar Department of Pharmaceutical Sciences and Natural Products Central University of Punjab

Genus Prunus comprising around 430 species is a vast important genus of family Rosaceae, subfamily amygdalaoidae. Among all 430 species, around 19 important species are commonly found in Indian subcontinent due to their broad nutritional and economic importance. Some most common species of genus Prunus are Prunus amygdalus, Prunus persica, Prunus armeniaca, Prunus avium, Prunus cerasus, Prunus cerasoides, Prunus domestica, Prunus mahaleb, etc. A newly introduced species of Prunus i.e Prunus sunhangii is recently discovered which is morphologically very similar to Prunus cerasoides. Plants of Prunus species are short to medium-sized deciduous trees mainly found in the northern hemisphere. In India and its subcontinent,it extends from the Himalayas to Sikkim, Meghalaya,Bhutan, Myanmar etc. Different Prunus species have been extensively studied for their morphological,microscopic, pharmacological and phytoconstituents characteristics. Total phenolic content of Prunus species explains the presence of phenols in high quantity and pharmacological activity due to phenols. Phytochemical screening of species of genus Prunus shows the presence of wide phytoconstituents which contributes in their pharmacological significance and reveals the therapeutic potential and traditional medicinal significance of this genus. Genus Prunus showed a potent antioxidant activity analyzed by 1,1-diphenyl-2-picryl-hydrazyl radical assay. Plant species belonging to the genus Prunus is widely used traditionally for the treatment of various disorders. Some specific Prunus species possess potent anticancer, anti-inflammatory,hypoglycemic etc. activity which makes the genus more interesting for further research and findings. This review is an attempt to summarize the comprehensive study of Prunus species from its distribution, morphological characters to phytoconstituents, and pharmacological activity.

关键词： Prunus Rosaceae antineoplastic agents distribution hypoglycemic agents phytochemistry review

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Generating A New Shilling Attack for Recommendation Systems

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Computers, Materials & Continua 2022年第5期71卷 2827-2846页

作者： pradeep kumar singh Pijush Kanti Dutta Pramanik Madhumita Sardar Anand Nayyar Mehedi Masud Prasenjit Choudhury Department of Computer Science&Engineering National Institute of TechnologyDurgapurIndia Graduate School Duy Tan UniversityDa NangVietnam Faculty of Information Technology Duy Tan UniversityDa NangVietnam Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia

A collaborative filtering-based recommendation system has been an integral part of e-commerce and *** keep the recommendation systems reliable,authentic,and superior,the security of these systems is very *** the existing shilling attack detection methods in collaborative filtering are able to detect the standard attacks,in this paper,we prove that they fail to detect a new or unknown *** develop a new attack model,named Obscure attack,with unknown features and observed that it has been successful in biasing the overall top-N list of the target users as *** Obscure attack is able to push target items to the top-N list as well as remove the actual rated items from the *** proposed attack is more effective at a smaller number of k in top-k similar user as compared to other existing *** effectivity of the proposed attack model is tested on the MovieLens dataset,where various classifiers like SVM,J48,random forest,and naïve Bayes are utilized.

关键词： Shilling attack recommendation system collaborative filtering top-N recommendation biasing shuffling hit ratio

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Gas hydrate saturation from NGHP 02 LWD data in the Mahanadi Basin

Energy Geoscience

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Energy Geoscience 2024年第2期5卷 279-289页

作者： Uma Shankar pradeep kumar Yadav Sneha Devi Udham singh Yadav Department of Geophysics Institute of ScienceBHUVaranasi221005India Oil and Natural Gas Corporation Ltd. Gas Hydrate Research&Technology Centre(GHRTC)Panvel410221Navi MumbaiIndia

During the Indian National Gas Hydrate Program(NGHP)Expedition 02,Logging-while-drilling(LWD)logs were acquired at three sites(NGHP-02-11,NGHP-02-12,and NGHP-02-13)across the Mahanadi Basin in area *** applied rock physics theory to available sonic velocity logs to know the distribution of gas hydrate at site NGHP-02-11 and *** physics modeling using sonic velocity at well location shows that gas hydrate is distributed mainly within the depth intervals of 150-265 m and 100 -215 mbsf at site NGHP-02-11 and NGHP-02-13,respectively,with an average saturation of about 4%of the pore space and the maximum concentration of about 40%of the pore space at 250 m depth at site NGHP-02-11,and at site NGHP-02-13 an average saturation of about 2%of the pore space and the maximum concentration of about 20%of the pore space at 246 m depth,as gas hydrate is distributed mainly within 100-246 mbsf at this *** of gas hydrate estimated from the electrical resistivity method using density derived porosity and electrical resistivity logs from Archie's empirical formula shows high saturation compared to that from the sonic ***,estimates of hydrate saturation based on sonic P-wave velocity may differ significantly from that based on resistivity,because gas and hydrate have higher resistivity than conductive pore fluid and sonic P-wave velocity shows strong effect on gas hydrate as a small amount of gas reduces the velocity significantly while increasing velocity due to the presence of *** site NGHP-02-11,gas hydrate saturation is in the range of 15%e30%,in two zones between 150-180 and 245-265 *** NGHP-02-012 shows a gas hydrate saturation of 20%e30%in the zone between 100 and 207 *** NGHP-02-13 shows a gas hydrate saturation up to 30%in the zone between 215 and 246 *** observations from rock physics modeling and Archie’s approximation show the gas hydrate concentrations are relatively low(<4%of the pore space)at the sites of the

关键词： Mahanadi Basin Gas hydrate Sonic log Effective medium modeling Electrical resistivity log Archie’s analysis Gas hydrate saturation

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Unlocking new potential of clinical diagnosis with artificial intelligence:Finding new patterns of clinical and lab data

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World Journal of Diabetes 2024年第3期15卷 308-310页

作者： pradeep kumar Dabla Department of Biochemistry Govind Ballabh Pant Institute of Postgraduate Medical Education and ResearchDelhi 110002India

Recent advancements in science and technology,coupled with the proliferation of data,have also urged laboratory medicine to integrate with the era of artificial intelligence(AI)and machine learning(ML).In the current practices of evidencebased medicine,the laboratory tests analysing disease patterns through the association rule mining(ARM)have emerged as a modern tool for the risk assessment and the disease stratification,with the potential to reduce cardiovascular disease(CVD)*** are the well recognised leading global cause of mortality with the higher fatality rates in the Indian population due to associated factors like hypertension,diabetes,and lifestyle ***-driven algorithms have offered deep insights in this field while addressing various challenges such as healthcare systems grappling with the physician *** medicine,well driven by the big data necessitates the integration of ML techniques and high-quality electronic health records to direct the meaningful *** technological advancements enhance the computational analyses for both research and clinical *** plays a pivotal role by uncovering meaningful relationships within databases,aiding in patient survival prediction and risk factor *** potential in laboratory medicine is vast and it must be cautiously integrated while considering potential ethical,legal,and privacy ***,an AI ethics framework is essential to guide its responsible *** AI algorithms with existing lab practices,promoting education among healthcare professionals,and fostering careful integration into clinical settings are imperative for harnessing the benefits of this transformative technology.

关键词： Laboratory medicine Artificial intelligence Machine learning Association rule mining Cardiovascular diseases

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Effect of cooling media on bead geometry,microstructure,and mechanical properties of wire arc additive manufactured IN718 alloy

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Advances in Manufacturing 2024年第1期12卷 124-149页

作者： Parveen kumar Satish kumar Sharma Ratnesh kumar Raj singh Department of Mechanical Engineering Thapar Institute of Engineering and TechnologyPatialaPunjab147004India

This work aims to present and explore thermal management techniques for the wire arc additive manufacturing(WAAM)of IN718 *** heat can be mitigated via air or water *** this study,the material was deposited under four different heat-input conditions with air or water *** air cooling,the layer is deposited in a normal atmospheric air environment,whereas with water cooling,the material is deposited inside a water tank by varying the water *** validate the air and water cooling thermal management techniques,IN718 single-pass and multilayer linear walls were deposited using the bidirectional gas metal arc welding based WAAM setup under four different heat input *** the deposition of single layers,the temperature profiles were recorded,and the geometric and microstructural features were *** multilayer wall structures,the mechanical properties(hardness,tensile strength,and elongation)were determined and assessed using the corresponding microstructural features explored through scanning electron microscopy(SEM),energy dispersive spectroscopy(EDS),and electron backscatter diffraction(EBSD)*** microstructure observed through SEM analysis in the building direction was found to be nonhomogenous compared with that in the deposition ***,water cooling was found to govern bead characteristics,such as wall width and *** grain size and anisotropy of the mechanical properties also decreased in the water-cooled ***,water cooling is an economical and efficient method to mitigate excessive heat accumulation in WAAM-deposited IN718.

关键词： Air cooling Water cooling IN718 Bead characteristics Microstructure Electron backscatter diffraction(EBSD)

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Thermodynamic properties and phase diagram of quark matter within non-extensive Polyakov chiral SU(3)quark mean field model

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Chinese Physics C 2024年第5期48卷 60-71页

作者： Dhananjay singh Arvind kumar Department of Physics Dr.B R Ambedkar National Institute of Technology JalandharJalandhar–144008PunjabIndia

In the present study,we applied Tsallis non-extensive statistics to investigate the thermodynamic properties and phase diagram of quark matter in the Polyakov chiral SU(3)quark mean field *** this model,the properties of the quark matter were modified through the scalar fieldsσ,ζ,δ,χ,vector fieldsω,ρ,ϕ,and Polyakov fieldsΦandΦ¯at finite temperature and chemical ***-extensive effects were introduced through a dimensionless parameter q,and the results were compared to those of the extensive case(q→1).In the non-extensive case,the exponential in the Fermi-Dirac(FD)function was modified to a q-exponential *** influence of the q parameter on the thermodynamic properties,pressure,energy,and entropy density,as well as trace anomaly,was *** speed of sound and specific heat with non-extensive effects were also ***,the effect of non-extensivity on the deconfinement phase transition as well as the chiral phase transition of u,d,and s quarks was *** found that the critical end point(CEP),which defines the point in the(T−μ)phase diagram where the order of the phase transition changes,shifts to a lower value of temperature,TCEP,and a higher value of chemical potential,μCEP,as the non-extensivity is increased,that is,q>1.

关键词： quark matter quark mean field model QCD phase diagram non-extensive statistics

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CFD modeling to study the effect of particle size on dispersion in 20l explosion chamber: An overview

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International Journal of Mining Science and Technology 2020年第3期30卷 321-327页

作者： Santosh kumar Ray Niroj kumar Mohalik Asfar Mobin Khan Debashish Mishra Nikhil kumar Varma Jai Krishna Pandey pradeep kumar singh CSIR-Central Institute of Mining and Fuel Research Dhanbad 826001India

Mine disasters occur predominantly due to methane or coal dust explosion or a combination of *** the top ten worst coal mine disasters in India, nine are due to coal dust explosion. The current paper describes a general overview of the parameters causing dispersion leading to coal dust explosion,and computational fluid dynamics(CFD) simulation study to observe the effects of particle size on dispersion in Indian coal mines. Turbulent kinetic energy(TKE) and velocity vector path of dust-air mixture and dust-free air were simulated to understand their effects on coal dust dispersion. The TKE contours and velocity vector paths for dust-free air were uniform and symmetrical due to resistance-free path available. The TKE contours and velocity vector paths for dust-air mixture shows the asymmetrical distribution of contours, due to entrainment of air with dust particles. Vortices were observed in velocity vector paths which gradually diminish on increment of time sequence. These vortices are dead centres where velocity and coal dust particles concentration are both zero.

关键词： Coal dust explosibility CFD 20l explosion chamber Dispersion Turbulent kinetic energy

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DNACDS:Cloud IoE big data security and accessing scheme based on DNA cryptography

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Frontiers of Computer Science 2024年第1期18卷 157-170页

作者： Ashish singh Abhinav kumar Suyel NAMASUDRA School of Computer Engineering KIIT Deemed to be UniversityBhubaneshwar 751024India Department of Computer Science and Engineering Indian Institute of Information Technology SuratSurat 394190India Department of Computer Science and Engineering National Institute of Technology AgartalaAgartala 799046India

The Internet of Everything(IoE)based cloud computing is one of the most prominent areas in the digital big data *** approach allows efficient infrastructure to store and access big real-time data and smart IoE services from the *** IoE-based cloud computing services are located at remote locations without the control of the data *** data owners mostly depend on the untrusted Cloud Service Provider(CSP)and do not know the implemented security *** lack of knowledge about security capabilities and control over data raises several security *** Acid(DNA)computing is a biological concept that can improve the security of IoE big *** IoE big data security scheme consists of the Station-to-Station Key Agreement Protocol(StS KAP)and Feistel cipher *** paper proposed a DNA-based cryptographic scheme and access control model(DNACDS)to solve IoE big data security and access *** experimental results illustrated that DNACDS performs better than other DNA-based security *** theoretical security analysis of the DNACDS shows better resistance capabilities.

关键词： IoE based cloud computing DNA cryptography IoE big data security StS KAP feistel cipher IoE big data access

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Application of Response Surface Methodology for Analysing and Optimizing the Finned Solar Air Heater

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Journal of Thermal Science 2024年第3期33卷 985-1009页

作者： Vineet singh Vinod singh YADAV Vaibhav TRIVEDI Manoj kumar Niraj kumar Department of Mechanical Engineering School of Engineering&TechnologyIFTM UniversityMoradabadUttar PradeshIndia Department of Mechanical Engineering NITUttarakhandPauriUttarakhandIndia Department of Electronics and Communication Engineering Jaypee Institute of Information TechnologyNoidaUttar Pradesh201309India

In this research paper,a solar air heater with triangular fins has been experimentally analysed and ***,an experimental set-up of a solar air heater having triangular fins has been developed at the location of 28.10°N,78.23°*** heat transfer rate through fins and fins efficiency has been determined by the Finite Difference Method model *** experimental data and modeled data of response parameters have been optimized in MINITAB-17 software by the Response Surface Methodology *** creating the response surface design,three input parameters have been selected namely solar intensity,Reynolds number,and fin base-to-height *** range of solar intensity,Reynolds number,and fin base-to-height ratio is 600 to 1000W/m^(2),4000 to 6000,and 0.4 to 0.8 *** response surface design has been analyzed by calculating the outlet temperature,friction factor,Nusselt number,fin efficiency,thermal performance factor,and exergy *** optimum settings of input parameters:solar intensity is 1000 W/m^(2);Reynolds number is 4969.7,and the fin base to height ratio is 0.6060,on which these response:namely outlet temperature of 92.531℃,friction factor of 0.2350,Nusselt number of 127.761,thermal efficiency of 50.836%,thermal performance factor of 1.4947,and exergy efficiency of 8.762%.

关键词： solar air heater optimization fins exergy response surface methodology air

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Constructing a biofunctionalized 3D-printed gelatin/sodium alginate/chitosan tri-polymer complex scaffold with improvised biological andmechanical properties for bone-tissue engineering

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Bio-Design and Manufacturing 2024年第1期7卷 57-73页

作者： Amit kumar singh Krishna Pramanik Amit Biswas Centre of Excellence in Tissue Engineering Department of Biotechnology and Medical EngineeringNational Institute of TechnologyRourkela 769008India

Sodium alginate(SA)/chitosan(CH)polyelectrolyte scaffold is a suitable substrate for tissue-engineering *** present study deals with further improvement in the tensile strength and biological properties of this type of scaffold to make it a potential template for bone-tissue *** experimented with adding 0%–15%(volume fraction)gelatin(GE),a protein-based biopolymer known to promote cell adhesion,proliferation,and *** resulting tri-polymer complex was used as bioink to fabricate SA/CH/GEmatrices by three-dimensional(3D)*** studies using scanning electron microscopy revealed the microfibrous porous architecture of all the structures,which had a pore size range of 383–419μm.X-ray diffraction and Fourier-transform infrared spectroscopy analyses revealed the amorphous nature of the scaffold and the strong electrostatic interactions among the functional groups of the polymers,thereby forming polyelectrolyte complexes which were found to improve mechanical properties and structural *** scaffolds exhibited a desirable degradation rate,controlled swelling,and hydrophilic characteristics which are favorable for bone-tissue *** tensile strength improved from(386±15)to(693±15)kPa due to the increased stiffness of SA/CH scaffolds upon addition of *** enhanced protein adsorption and in vitro bioactivity(forming an apatite layer)confirmed the ability of the SA/CH/GE scaffold to offer higher cellular adhesion and a bone-like environment to cells during the process of tissue *** vitro biological evaluation including the MTT assay,confocal microscopy analysis,and alizarin red S assay showed a significant increase in cell attachment,cell viability,and cell proliferation,which further improved biomineralization over the scaffold *** addition,SA/CH containing 15%gelatin designated as SA/CH/GE15 showed superior performance to the other fabricated 3D structures,demonstrating its pote

关键词： Scaffold Biomaterial Sodium alginate Chitosan Gelatin 3D printing Tissue engineering

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