检索结果-南通市图书馆

Effectiveness and safety of COVID-19 vaccines in patients with diabetes as a factor for vaccine hesitancy

World Journal of Diabetes 2022年第9期13卷 738-751页

作者： Georgi Vasilev plamena kabakchieva Dimitrina Miteva Hristiana Batselova Tsvetelina Velikova Faculty of Medicine Medical University of PlovdivPlovdiv 4000Bulgaria Clinic of Endocrinology University Hospital“Alexandrovska”Department of Internal MedicineMedical FacultyMedical UniversitySofia 1431Bulgaria Clinic of Internal Diseases Naval Hospital-VarnaMilitary Medical AcademyVarna 9010Bulgaria Department of Genetics Sofia University“St.Kliment Ohridski”Faculty of BiologySofia 1164Bulgaria Department of Epidemiology and Disaster Medicine Medical UniversityUniversity Hospital“St George”Plovdiv 4000Bulgaria Department of Clinical Immunology University Hospital LozenetzSofia 1407Bulgaria Medical Faculty Sofia University St.Kliment OhridskiSofia 1407Bulgaria

Diabetes mellitus is one of the most common comorbid conditions encountered in patients with severe acute respiratory syndrome coronavirus 2 infection accompanied by significantly increased mortality,prolonged hospital stay,and requirement of invasive mechanical *** review aims to present the effectiveness and safety profile of available coronavirus disease 2019(COVID-19)vaccines in people with diabetes as a potential cause of hesitancy for *** from published research proves a robust immune response following immunization for COVID-19 in diabetic patients with substantial production of virus-neutralizing antibodies;however,the observed immune response was unequivocally weaker than that in individuals without *** observation was further enhanced by the findings that worse glycemic control was associated with more suppressed antibody *** contrast,individuals with optimal glycemic control performed similarly to healthy *** addition to the need for strict glucose monitoring and adequate diabetes treatment,those findings reinforce the concept of diabetes-induced secondary immune deficiency and necessitate the application of booster doses to diabetic patients with ***,after vaccination,reported adverse events were not different from those in the general *** increase in severe adverse events was *** single case reports detected transient increases in blood glucose post-vaccination,more extensive trials could not replicate such a relationship.

关键词： COVID-19 COVID-19 vaccines Diabetes Vaccine effectiveness Vaccine Vaccine hesitancy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Islet transplantation-immunological challenges and current perspectives

引用

World Journal of Transplantation 2023年第4期13卷 107-121页

作者： plamena kabakchieva Yavor Assyov Stavros Gerasoudis Georgi Vasilev Monika Peshevska-Sekulovska Metodija Sekulovski Snezhina Lazova Dimitrina Georgieva Miteva Milena Gulinac Latchezar Tomov Tsvetelina Velikova Clinic of Internal Diseases Naval Hospital-VarnaMilitary Medical AcademyVarna 9010Bulgaria Clinic of Endocrinology Department of Internal DiseasesUniversity Hospital"Alexandrovska"Medical University-SofiaSofia 1434Bulgaria Faculty of Medicine Trakia UniversityStara Zagora 6000Bulgaria Department of Neurology Faculty of MedicineMedical University of PlovdivPlovdiv 4000Bulgaria Department of Gastroenterology University Hospital LozenetzSofia 1407Bulgaria Medical Faculty Sofia University St.Kliment OhridskiSofia 1407Bulgaria Department of Anesthesiology and Intensive Care University hospital LozenetzSofia 1407Bulgaria Department of Pediatric University Hospital"N.I.Pirogov"Sofia 1606Bulgaria Department of Healthcare Faculty of Public Health"Prof.Tsekomir VodenicharovMDDSc"Medical University of SofiaSofia 1527Bulgaria Department of Genetics Sofia University"St.Kliment Ohridski"Sofia 1164Bulgaria Department of General and Clinical Pathology Medical University of PlovdivPlovdiv 4000Bulgaria Department of Informatics New Bulgarian UniversitySofia 1618Bulgaria

Pancreatic islet transplantation is a minimally invasive procedure aiming to reverse the effects of insulin deficiency in patients with type 1 diabetes(T1D)by transplanting pancreatic beta ***,pancreatic islet transplantation has improved to a great extent,and cellular replacement will likely become the mainstay *** review pancreatic islet transplantation as a treatment for T1D and the immunological challenges *** data demonstrated that the time for islet cell transfusion varied between 2 and 10 *** 54%of the patients gained insulin independence at the end of the first year,while only 20%remained insulin-free at the end of the second ***,most transplanted patients return to using some form of exogenous insulin within a few years after the transplantation,which imposed the need to improve immunological factors before *** also discuss the immunosuppressive regimens,apoptotic donor lymphocytes,anti-TIM-1 antibodies,mixed chimerism-based tolerance induction,induction of antigen-specific tolerance utilizing ethylene carbodiimide-fixed splenocytes,pretransplant infusions of donor apoptotic cells,B cell depletion,preconditioning of isolated islets,inducing local immunotolerance,cell encapsulation and immunoisolation,using of biomaterials,immunomodulatory cells,etc.

关键词： Islet transplantation Type 1 diabetes Diabetes mellitus Immune tolerance Graft rejection T regulatory cells B regulatory cells

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Long-term effectiveness,outcomes and complications of bariatric surgery

引用

World Journal of Clinical Cases 2023年第19期11卷 4504-4512页

作者： Milena Gulinac Dimitrina Georgieva Miteva Monika Peshevska-Sekulovska Ivan P Novakov Svetozar Antovic Milena Peruhova Violeta Snegarova plamena kabakchieva Yavor Assyov Georgi Vasilev Metodija Sekulovski Snezhina Lazova Latchezar Tomov Tsvetelina Velikova Department of General and Clinical Pathology Medical University of PlovdivPlovdiv 4000Bulgaria Department of Genetics Sofia University"St.Kliment Ohridski"Faculty of BiologySofia 1164Bulgaria Department of Gastroenterology University Hospital LozenetzSofia 1407Bulgaria Department of Thoraco-abdominal Surgery Medical University PlovdivPlovdiv 6000Bulgaria University Clinic for Digestive Surgery Medical FacultySkopjeSkopje 1000North Macedonia Department of Gastroenterology Heart and Brain HospitalBurgasBurgas 1000Bulgaria Clinic of Internal Diseases Naval Hospital-VarnaMilitary Medical AcademyMedical FacultyMedical UniversityVarna 9000Bulgaria Clinic of Internal Diseases Naval Hospital-VarnaMilitary Medical AcademyVarna 9010Bulgaria Clinic of Endocrinology University Hospital AlexandrovskaSofia 1431Bulgaria Department of Internal Diseases Medical University–SofiaSofia 1431Bulgaria Clinic of Endocrinology and Metabolic Disorders UMHAT"Sv.Georgi"Plovdiv 4000Bulgaria Department of Anesthesiology and Intensive Care University Hospital LozenetzSofia 1407Bulgaria Medical Faculty Sofia UniversitySt.Kliment OhridskiSofia 1407Bulgaria Department of Pediatric University Hospital"N.I.Pirogov"Sofia 1606Bulgaria Department of Healthcare Faculty of Public Health"Prof.Tsekomir VodenicharovMDDSc"Sofia 1527Bulgaria Department of Informatics New Bulgarian UniversitySofia 1618Bulgaria Medical Faculty Sofia University St.Kliment OhridskiSofia 1407Bulgaria

Dietary imbalance and overeating can lead to an increasingly widespread *** considerations aside,obesity is defined as an excess of adipose tissue that can lead to serious health problems and can predispose to a number of pathological changes and clinical diseases,including diabetes;hypertension;atherosclerosis;coronary artery disease and stroke;obstructive sleep apnea;depression;weight-related arthropathies and endometrial and breast cancer.A body weight 20%above ideal for age,gender and height is a severe health *** surgery is a set of surgical methods to treat morbid obesity when other treatments such as diet,increased physical activity,behavioral changes and drugs have *** two most common procedures currently used are sleeve gastrectomy and gastric *** procedure has gained popularity recently and is generally considered safe and *** current data show that perioperative mortality is low and better control of comorbidities and short-term complications is achieved,more randomized trials are needed to evaluate the long-term outcomes of bariatric *** review aims to synthesize and summarize the growing evidence on the long-term effectiveness,outcomes and complications of bariatric surgery.

关键词： Bariatric surgery Long-term outcomes Obesity Roux-en-Y gastric bypass sleeve gastrectomy Effectiveness Safety Quality of life

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

电场或电磁场和光动力的协同效应对癌细胞失活和坏死的作用(英文)

引用

电化学 2004年第3期10卷 260-270页

作者： Maria Radeva Maya Lambrera plamena Angelova Nelly Traitcheva Hermann Berg Beutenberg大学生物电化学研究室德国耶纳

　应用弱正弦波电磁场改变细胞膜的穿透性并引起其失活和坏死.研究中,将人类癌细胞U 937和K 562放置于强度为10mT和39mT(50Hz)的正弦波电磁场内,并依次结合细胞毒素放线菌素 C以及其独特的光动力活性分别进行试验.

关键词：癌细胞失活坏死协同效应光动力正弦波电磁场放线菌素-C 细胞膜穿透性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

萌宠动物园

引用

中华手工 2015年第1期 34-35页

作者：孙凝异 plamena Doycheva

当漂流木遇上拉菲草,一座萌萌的迷你动物园就建成了。清晨,海风吹进保加利亚版画家Piamena Doycheva位于黑海边的屋子,伴她喝下第一杯咖啡,一只叫Gizmo的猫在她脚下乱窜。打开电脑,查看来自世界各地的订单,plamena再决定如何安排这一天... 详细信息

当漂流木遇上拉菲草,一座萌萌的迷你动物园就建成了。清晨,海风吹进保加利亚版画家Piamena Doycheva位于黑海边的屋子,伴她喝下第一杯咖啡,一只叫Gizmo的猫在她脚下乱窜。打开电脑,查看来自世界各地的订单,plamena再决定如何安排这一天的时光。微缩木雕、拉菲草编织、布艺制作、丝网印刷、剪纸设计、版画创作……plamena要做的"闲事"太多了。但最爱的,是用漂流木和拉菲草制作萌萌的微缩小物。plamena住在瓦尔纳,房子紧邻黑海。六年前的一个傍晚。

关键词：漂流木拉菲草版画创作丝网印刷瓦尔纳这一天小物你我木工活白蘑菇

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：