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海南医学 2021年第9期32卷 1173-1178页

作者：余杨张喜军盛平卫诸婧上海市金山区中西医结合医院外一科上海201501

银屑病是一种严重影响人体心身健康的慢性炎症性免疫性疾病,寻常型银屑病是其中最多见的一种类型。典型的寻常型银屑病组织病理学表现为表皮角化不全伴角化过度,炎症细胞浸润和血管扩张。皮肤中多种免疫细胞均参与了寻常型银屑病的发病... 详细信息

银屑病是一种严重影响人体心身健康的慢性炎症性免疫性疾病,寻常型银屑病是其中最多见的一种类型。典型的寻常型银屑病组织病理学表现为表皮角化不全伴角化过度,炎症细胞浸润和血管扩张。皮肤中多种免疫细胞均参与了寻常型银屑病的发病,如角质形成细胞、树突状细胞、T淋巴细胞、中性粒细胞、巨噬细胞等。本文重点综述寻常型银屑病免疫学机制中较为关键的免疫细胞及相应细胞因子的作用,并总结近年来中医药治疗寻常型银屑病免疫学作用机制的研究进展。

关键词：寻常型银屑病发病机制免疫细胞中医药治疗角质形成细胞树突状细胞 T淋巴细胞细胞因子

Effects of cyclodextrins on hydrolysis of malathion

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Journal of Environmental Sciences 2006年第3期18卷 572-576页

作者： ZHANG An-ping LUO Fan CHEN sheng-wen LIU wei-ping Institute of Environmental Science Zhejiang University Hangzhou 310029 China Research Center of Green Chirality College of Biological and Environmental Engineering Zhejiang University of Technology Hangzhou 310032 China

Cyclodextrins （CDs）, with hydrophobic interior cavity and hydrophilic external surface, are capable of accelerating or inhibiting chemical degradation of organophosphorus pesticides through forming inclusion complexes between CDs and pesticides. This work evaluated the effects of CDs on hydrolysis of malathion in an attempt to assess their potential application in environmental approach. β-CD and its two derivatives, randomly methylated β-CD （RAMEB） and hydroxypropyl β-CD （HP-β-CD）, were tested. It was found that RAMEB could inhibit the hydrolysis of malathion, and this was the function of pH and temperature, the inhibitory effects increase with increasing concentration of RAMEB and elevating temperature between 15 and 35℃. On the other hand, β-CD and HP-β-CD have little or no stabilizing effects on malathion at all pH and temperature studied, except that the large concentration of β-CD and HP- β-CD can mildly reduce hydrolysis of malathion. Both 2 mol/L and 5 mol/L urea increase the inhibitory effects of RAMEB on hydrolysis of malathion at 25℃, oH 9.0.

关键词： cyclodextrin malathion hydrolysis urea

Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

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Science China Life Sciences 2025年第1期 300-302页

作者： Ze-Min Lin Mai Xiang Wen-Hui wei Shu-Hui Fan Li Chen Jie Wang Xiao-Qian Yang Chun-Hao Yang Shi-Jun He Jian-ping Zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of Sciences School of Pharmacy University of Chinese Academy of Sciences School of Pharmacy Nanjing University of Chinese Medicine State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of Sciences Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine

Dear Editor, Phenotypic drug discovery, which observes compound effects on physiology,has given way to targeting specific molecules, but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al., 2022). Osteoarthritis(OA) is a prevalent chronic joint disorder, primarily affecting knee joints, with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).

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Visualization of Thermo-Hydrodynamic Behavior in Flat-Plate Pulsating Heat Pipe with HFE-347

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Journal of Thermal Science 2021年第3期30卷 926-938页

作者： YAN Lipei ZHANG ping XU Hui MA wei sheng Jiang School of Mechanical and Electrical Engineering Guilin University of Electronic TechnologyGuangxi 541004China Science and Technology on Space Physics Laboratory China Academy of Launch Vehicle TechnologyBeijing 100094China

In this paper,the visualization of the thermo-hydrodynamic behavior in flat-plate pulsating heat pipe(FP-PHP)with HFE-347 is experimentally *** FP-PHP is vertically placed with filling rate of 20%to 70%and heating power of 20 W to 140 W.A high-speed camera is used to record the two-phase flow in the *** flow pattern types and four flow directions are *** flow directions of the two-phase flow inside the FP-PHP with medium filling rate(40%–60%)are the most complex,and the FP-PHP with high filling rate(70%)is most likely to form a directional circulating *** high heating power(100 W to 140 W),the flow patterns in FP-PHP with medium(40%–60%)and high filling rate(70%)are dominated by mixed *** wall temperature fluctuates greatly at moderate heating power(60 W to 80 W)owing to the uncertainty of the flow *** temperature distribution of the FP-PHP is highly affected by the heat transfer intensity of the working fluid under different flow states,so that the state of fluid flow and the thermal performance of FP-PHP can be evaluated through the infrared thermal image of the FP-PHP.

关键词： flat-plate pulsating heat pipe HFE-347 visualization thermal performance infrared thermal imaging

Two-agent single machine scheduling with forbidden intervals

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Applied Mathematics(A Journal of Chinese Universities) 2015年第1期30卷 93-101页

作者： FENG Qi LI Shi-sheng SHANG wei-ping College of Science Zhongyuan University of Technology School of Mathematics and Statistics Zhengzhou University

We consider the resumable version of the two-agent single machine scheduling prob- lems with forbidden intervals in which the jobs cannot be processed. The goal is to minimize the sum of the objective functions of the two agents. Polynomial and pseudo-polynomial time algorithms are presented for various combinations of regular scheduling objective functions.

关键词： two-agent scheduling dynamic programming forbidden interval.

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龙胆泻肝汤减味治疗急性期湿疹临床研究

中国实用医药 2019年第27期14卷 8-10页

作者：诸婧张金华盛平卫张喜军上海市金山中西医结合医院外一科

目的探究龙胆泻肝汤减味治疗急性期湿疹的疗效。方法 60例急性期湿疹患者,采用信封法分为龙胆泻肝汤减味组与抗过敏药物组,每组30例。龙胆泻肝汤减味组2例退出,完成28例;抗过敏药物组4例退出,完成26例。龙胆泻肝汤减味组给予龙胆泻肝汤... 详细信息

目的探究龙胆泻肝汤减味治疗急性期湿疹的疗效。方法 60例急性期湿疹患者,采用信封法分为龙胆泻肝汤减味组与抗过敏药物组,每组30例。龙胆泻肝汤减味组2例退出,完成28例;抗过敏药物组4例退出,完成26例。龙胆泻肝汤减味组给予龙胆泻肝汤减味中药汤剂联合醋酸氟轻松软膏治疗,抗过敏药物组给予口服盐酸左西替利嗪片联合醋酸氟轻松软膏治疗。观察比较两组临床疗效以及皮损情况。结果龙胆泻肝汤减味组临床治疗总有效率82.14%明显高于抗过敏药物组的53.85%,差异具有统计学意义(P<0.05);治疗后,龙胆泻肝汤减味组皮损积分(8.69±2.29)分低于抗过敏药物组的(10.73±1.91)分,差异具有统计学意义(P<0.05)。结论龙胆泻肝汤减味和抗过敏药物均能治疗急性期湿疹,但前者临床疗效优于后者。

关键词：龙胆泻肝汤减味急性期湿疹中药

马克思批判性研究思路中的问题意识及其思考的系统性

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广西师范大学学报（哲学社会科学版） 2025年第1期61卷 1-10页

作者：魏小萍新疆大学马克思主义学院新疆乌鲁木齐830046 中国社会科学院大学哲学系北京102488

马克思批判性研究思路从早期的法学、哲学、道德视域的思考深入到现实社会经济关系领域,并转向政治经济学批判性研究,与此相应,马克思关注的问题意识也随着研究思路的进程发生着相应变化。这些问题意识彼此之间并非互不相干,它们围绕着... 详细信息

马克思批判性研究思路从早期的法学、哲学、道德视域的思考深入到现实社会经济关系领域,并转向政治经济学批判性研究,与此相应,马克思关注的问题意识也随着研究思路的进程发生着相应变化。这些问题意识彼此之间并非互不相干,它们围绕着马克思的核心研究思路,即人类解放理念而展开。这一理念由早期抽象的自由和平等发展到在新历史观视域下以生产手段社会占有为基础的全面自由和以超越回馈正义原则为基础的现实平等。贯穿于马克思哲学思考与政治经济学批判性研究之间的是政治哲学思考。以这一脉络为线索,我们能在马克思不同时期、不同领域研究思路的问题域中看到其研究思路的内在连续性与系统性。

关键词：马克思劳动所得双重对象性关系批判思路

涂装自行葫芦输送系统自动化上下件的设计及应用

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现代涂料与涂装 2018年第3期21卷 34-36,40页

作者：肖坤邢汶平吴贵生魏红亮李静安徽江淮汽车集团股份有限公司技术中心合肥230601

主要介绍了自行葫芦输送系统实现自动化上下件的设计思路及详细实施方案。该自动化系统可实现工艺节拍的最大化、生产效率的最优化和人工成本的最小化,为今后新建涂装线设计或现有工厂改造自行葫芦输送系统提供了一些参考和思路。

关键词：涂装自行葫芦输送系统地面滑橇输送系统自动化上下件节拍

白玉膏联合五黑散治疗小儿尿布皮炎的临床观察

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河南中医 2022年第6期42卷 928-930页

作者：盛平卫陈婕妤诸婧顾敏婕上海市金山区中西医结合医院上海201501 上海中医药大学附属龙华医院上海200030

目的:观察白玉膏联合五黑散治疗小儿尿布皮炎的临床疗效。方法:选择在上海市金山区中西医结合医院门诊及病房治疗的80例尿布皮炎患儿为研究对象,采用随机数字表法分为对照组和治疗组各40例,对照组在基础护理的基础上采用莫匹罗星软膏联... 详细信息

目的:观察白玉膏联合五黑散治疗小儿尿布皮炎的临床疗效。方法:选择在上海市金山区中西医结合医院门诊及病房治疗的80例尿布皮炎患儿为研究对象,采用随机数字表法分为对照组和治疗组各40例,对照组在基础护理的基础上采用莫匹罗星软膏联合爽身粉外涂治疗,治疗组在基础护理的基础上采用白玉膏联合五黑散外涂治疗。观察两组患儿治疗后皮损程度评分、面部表情疼痛量表(faces pain scale-revised,FPS-R)评分及皮肤红斑、糜烂消退时间,比较两组患儿的临床疗效。结果:治疗组皮损程度评分低于对照组,差异有统计学意义(P<0.05);治疗组FPS-R评分低于对照组,差异有统计学意义(P<0.05);治疗组患儿疮面愈合时间短于对照组,差异具有统计学意义(P<0.05);对照组治愈率为75.0%,治疗组治愈率为87.5%,两组治愈率比较,差异有统计学意义(P<0.05)。结论:白玉膏联合五黑散治疗小儿尿布皮炎,可缩短疮面愈合时间,改善患儿临床症状。

关键词：小儿尿布皮炎白玉膏五黑散莫匹罗星软膏外涂疗法