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Lubricating properties of ester oil prepared from bio-based 2,5-furandicarboxylic acid

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Friction 2020年第2期8卷 360-369页

作者： Mingjin FAN Jia Al Shuai ZHANG Chenlu YANG Xin DU ping wen Xiangyuan YE Feng ZHOU Weiming LIU Shanxi Key Laboratory of Phytochemistry College of Chemistry&Chemical EngineeringBaoji University of Arts and SciencesBaoji 721013China State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China College of Chemistry and Molecular Science Wuhan UniversityWuhan 430072China

The depletion of petroleum resources and the intensification of environmental problems have necessitated the development of renewable products from bio-based chemicals instead of petroleum ***,a new kind of ester lubricating oil,isooctyl furan dicarboxylate(isooctyl-FD),was prepared from bio-based 2,5-furandicarboxylic *** structure of isooctyl-FD was evaluated using nuclear magnetic resonance imaging and high-resolution mass *** physicochemical and tribological properties including thermal and oxidation stabilities,flash point and pour point,viscosity and viscosity index,and friction-reducing and anti-wear properties were systematically *** results show that isooctyl-FD has comparable thermal and oxidation stability to the synthetic ester lubricating oil,isooctyl sebacate(isooctyl-S).Its friction-reducing and anti-wear properties are superior to isooctyl-S;however,its viscosity-temperature and low-temperature properties are inferior to isooctyl-S.

关键词： 2,5-furandicarboxylic acid synthetic ester bio-based platform compound lubricating oil

The first photometric investigations of the G-type shallow contact binary IO Cnc

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Research in Astronomy and Astrophysics 2021年第2期21卷 133-141页

作者： wen-ping Liao Lin-Jia Li Xiao Zhou Qi-Shan Wang Yunnan Observatories Chinese Academy of SciencesKunming 650216China Key Laboratory for the Structure and Evolution of Celestial Objects Chinese Academy of SciencesKunming 650216China Center for Astronomical Mega-Science Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China

IO Cnc was classified to be a new G-type(G0)W UMa-type eclipsing binary *** first multicolor photometric solutions show that IO Cnc is a new W-subtype shallow contact binary with a fill-out factor of f=16.1%and a low mass ratio of q=3.12(or 1/q=0.32).During orbital period investigations,a cyclic variation and a downward parabolic variation with a rate of(-1.28±0.43)×10^(-7) d yr^(-1) was discovered in the observed–calculated(O-C)*** cyclic variation was analyzed by the light travel time effect(LTTE)via a potential red dwarf companion star,an orbital semi-major axis shorter than 4.88±0.82 AU was ***,we collect physical parameters of a sample of 50 G-type shallow contact binaries(f≤20%),it is suggested that most of the G-type shallow contact binaries are undergoing a longterm and periodic orbital period changes,especially more systems show long-term *** long-term orbital period decrease indicates that IO Cnc is in a mass transferring from the more massive component to the less massive *** the long-term decrease of the orbital period,this shallow contact binary will evolve into a deeper contact one.

关键词： stars binaries close-stars binaries eclipsing-stars individual(IOCnc)-stars solar-type-stars evolution

Botulinum toxin type A in treating early-stage patients with small-angle acute acquired comitant esotropia

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International Journal of Ophthalmology(English edition) 2024年第6期17卷 1094-1101页

作者： Run-Ting Ma Die-wen-Jie Hu Lian-Hong Zhou wen-ping Li Yuan-Jin Li Bei-Xi Yi Department of Ophthalmology Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina

AIM:To investigate botulinum toxin A(BTXA)efficacy on small-angle(≤25Δ)acute acquired concomitant esotropia(AACE)in early-stage ***:The electronic medical record data of AACE patients during March 2019 and June 2023 were collected in this retrospective and hospital-based cohort study.A total of 72 small-angle AACE patients received BTXA extraocular muscle *** were grouped by onset-to-treatment time(Group A:≤6mo,Group B:>6mo).Deviation of esotropia,eye alignment and stereopsis were analyzed at the period of pre/post-injection(1wk,1,3,and 6mo).Orthophoria rate at 6mo(horizontal deviation0.05)between two groups except onset-to-treatment time(2mo vs 11mo,P0.05);while in 3 and 6mo Group A was significantly smaller than group B(all P6mo)may reduce BTXA *** BTXA intervention benefits long-term eye alignment and stereopsis recovery.

关键词： acute acquired comitant esotropia botulinum toxin type A stereopsis

Synthesis of optically active polymers bearing amino acid moieties by atom transfer radical polymerization

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Chinese Chemical Letters 2007年第7期18卷 875-878页

作者： Liang Feng Fa Bao Zhao Zhi Lei Liu Jian ping Sun Ji wen Hu Guangzhou Institute of Chemistry Chinese Academy of Sciences Guangzhou 510650 China

We report here an approach toward the synthesis of optically active polyacrylamide bearing amino acid moieties, poly[Nmethacryloyl L-leucine methyl ester] （PMALM）, with controlled average number molecular weight （Mn） and relatively narrow polydispersity index （PDI, Mw/Mn 〈 1.3） by atom transfer radical polymerization （ATRP） using initiating system methyl 2-bromopropionate/CuBr/tris（2-dimethylaminoethyl） amine. The optical properties of the resulting polymers were evaluated from specific optical rotation value and CD spectra.

关键词： Optically active polymer Atom transfer radical polymerization Poly[N-methacryloyl L-leucine methyl ester]

Nootkatone Improves Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors by Repressing NF-κB/NLRP3-Mediated Neuroinflammation

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Chinese Journal of Integrative Medicine 2023年第1期29卷 37-43页

作者： ZHAO Xin-hua AN Na XIA Meng-huan LIU wen-ping WANG Qing-qi BAO Ji-zhang Basic Medical College Shanghai University of Traditional Chinese MedicineShanghai201203China Geriatrics Department Shanghai Mental Health CenterShanghai200030China Hematological Department Shanghai Municipal Hospital of Traditional Chinese MedicineShanghai University of Traditional Chinese MedicineShanghai200071China

Objective:To explore the effect of nootkatone(NKT) on chronic unpredictable mild stress(CUMS)-induced depressive-like behaviors and the mechanism underlying NKT improving the depressivelike ***:The CUMS-induced depression model was established in *** mice were randomized into 5 groups(n=10) in accordance with a random number table:control group,CUMS group,CUMS+NKT(6 mg/kg) group,CUMS+NKT(12 mg/kg) group,and CUMS+ketamine *** the 22th day,NKT(6 or 12 mg/kg) or ketamine(0.5 mg/kg) was given with intragastric administration every day for21 *** tests including forced swimming test(FST),tail suspension test(TST),sucrose preference test(SPT) and open-field test(OFT) were carried *** mRNA and protein expressions of interleukin(IL)-1β,IL-18,IL-6,and tumor necrosis factor(TNF)-α in hippocampus were assessed using quantitative realtime polymerase chain reaction(PCR),Western blot analysis,and enzyme linked immunosorbent *** nuclear factor-κB(NF-κB)/NOD-like receptor 3(NLRP3) inflammasome pathway was analyzed using Western blot and immunofluorescence ***:NKT treatment improved CUMS-induced depressivelike behaviors in mice(P<0.05 or P<0.01).NKT significantly decreased the mRNA and protein levels of IL-1β,IL-18,IL-6,and TNF-α in hippocampus of CUMS mice(P<0.05 or P<0.01).Furthermore,NKT repressed CUMS-induced activation of NF-κB signaling and NLRP3 inflammasome(P<0.01).More important,Nigericin,a NLRP3 activator,destroyed the effect of NKT on repressing neuroinflammation and improving depressive-like behaviors(P<0.05 or P<0.01).Conclusion:NKT ameliorates the depressive-like symptoms,in part by repressing NF-κB/NLRP3-mediated neuroinflammation.

关键词： nootkatone depressive disorder nuclear factor-κB NOD-like receptor 3 nuroinflammation

From immunology to artificial intelligence: revolutionizing latent tuberculosis infection diagnosis with machine learning

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Military Medical Research 2024年第5期11卷 747-784页

作者： Lin-Sheng Li Ling Yang Li Zhuang Zhao-Yang Ye Wei-Guo Zhao wen-ping Gong Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment Senior Department of Tuberculosisthe Eighth Medical Center of PLA General HospitalBeijing100091China Hebei North University Zhangjiakou075000HebeiChina Senior Department of Respiratory and Critical Care Medicine the Eighth Medical Center of PLA General HospitalBeijing100091China

Latent tuberculosis infection(LTBI)has become a major source of active tuberculosis(ATB).Although the tuberculin skin test and interferon-gamma release assay can be used to diagnose LTBI,these methods can only differentiate infected individuals from healthy ones but cannot discriminate between LTBI and ***,the diagnosis of LTBI faces many challenges,such as the lack of effective biomarkers from Mycobacterium tuberculosis(MTB)for distinguishing LTBI,the low diagnostic efficacy of biomarkers derived from the human host,and the absence of a gold standard to differentiate between LTBI and *** culture,as the gold standard for diagnosing tuberculosis,is time-consuming and cannot distinguish between ATB and *** this article,we review the pathogenesis of MTB and the immune mechanisms of the host in LTBI,including the innate and adaptive immune responses,multiple immune evasion mechanisms of MTB,and epigenetic *** on this knowledge,we summarize the current status and challenges in diagnosing LTBI and present the application of machine learning(ML)in LTBI diagnosis,as well as the advantages and limitations of ML in this ***,we discuss the future development directions of ML applied to LTBI diagnosis.

关键词： Tuberculosis(TB) Latent tuberculosis infection(LTBI) Machine learning(ML) Biomarkers Differential diagnosis

Chloride transport and its sensitivities to different boundary conditions in reclaimed soil solutions filled with fly ash

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Journal of Coal Science & Engineering(China) 2013年第2期19卷 249-255页

作者： Xiao-Yang CHEN Jia-ping YAN Shi-wen ZHANG School of Earth and Environment Anhui University of Science and Technology Huainan 232001 China

Chloride ion transport in reclaimed soil solutions filled with fly ash （FA） was investigated by measuring the hydraulic parameters （i,e. water retention curves and hydraulic conductivity） of three substrates, namely GSL, GFA, and CFA. Similar simulations were carried out under certain weather conditions. The different boundary conditions of chloride transport were also discussed from FA texture, cover soil thickness, groundwater table level, and initial chloride concentration. Furthermore, the sensitivities of chloride ions to these effect factors were analyzed. The results show that the different top soil thickness and initial chloride concentration have no effect on salinity of topsoil solution in the monitoring points, but they can clearly change the chloride concentration of FA layers. The sensibilities from top soil thickness and initial chloride content are exceedingly weak to the salinity balance based on two dimensions of the time and concentration. While the different FA texture and groundwater table not only affect the salinity equilibrium process of the whole reclaimed soil profile, but also change its balance state. Generally, coarse FA particles and high groundwater table can defer the salinity balance process of the reclaimed soil solution, and they also increase the chloride concentration of FA layer solutions, and even topsoil ones.

关键词： chloride ion transport reclaimed soil fly ash boundary condition sensitivity

Mechanical properties and corrosion behavior of a new RRA-treated Al-Zn-Mg-Cu-Er-Zr alloy

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Rare Metals 2023年第2期42卷 672-679页

作者： Jun-Tai Lu Hui Huang Hao Wu Sheng-ping wen Kun-Yuan Gao Xiao-Lan Wu Zuo-Ren Nie School of Materials Science and Engineering Beijing University of TechnologyBeijing100124China

The effect of various retrogression and re-aging(RRA)treatments on mechanical properties and corrosion behavior of a new type Al-Zn-Mg-Cu-Er-Zr alloy was investigated by microhardness testing,tensile testing,intergranular corrosion(IGC)and exfoliation corrosion(EXCO)*** results show that the RRA treatment can effectively improve the IGC and EXCO resistance with less strength sacrificing because the grain interior precipitates and the grain boundary precipitates are similar to that of T6 temper and T73 ***,as the microhardness of the retrogressed alloy reaches the peak value during the retrogression at 170℃,the corresponding RRA-treated alloy possesses the better strength,but the corrosion resistance is poor in comparison with that of the retrogression at 190℃.The optimal combination of strength,IGC and EXCO resistance is obtained after retrogression at 180℃for 60 ***,for different heat treatment tempers,the corresponding micros true tural evolution of the precipitates including Al_(3)(Er,Zr)particles was also discussed in detail.

关键词： Al-Zn-Mg-Cu-Er-Zr alloy RRA treatment Mechanical properties Corrosion behavior

Portal inflow preservation during portal diversion in small-for-size syndrome

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World Journal of Gastroenterology 2014年第4期20卷 1021-1029页

作者： Xian-Qiang Wang Yue-Fang Xu Jing-Wang Tan wen-ping Lv Zhe Liu Jian-ping Zeng Jia-Hong Dong Department of Hepatobiliary Surgery Qilu Hospital Shandong University Department of Hepatobiliary Surgery the Chinese PLA General Hospital Department of Pharmacology First Hospital Affiliated to the Chinese PLA General Hospital Department of Hepatobiliary Surgery First Hospital Affiliated to the Chinese PLA General Hospital

AIM: To investigate the impact of portal inflow on liver remnants in a stable pig model of small-for-size syndrome.

关键词： Portal flow Portal diversion Small-for-size syndrome Mesocaval shunt