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世界核心医学期刊文摘（胃肠病学分册） 2006年第1期2卷 45-45页

作者： Del.’Aquil. P. pietrini l. Barone M. E. Ierardi 郑世成 Cattedra di Gastroenterol.gia Università di Foggia c/o Ospedali Riuniti Viale L. Pinto 71 100 Foggia Italy Dr.

Background: Smal. intestinal.ul.rasonography with anechoic contrast agents (SICUS) has been shown to have a diagnostic accuracy on smal. bowel.morphol.gy simil.r to X-ray barium fol.ow-through. Al.hough extremel. investigated by transabdominal.ul.rasonography, cel.ac disease, a common disorder of the smal. bowel. has been never studied by SICUS. Aim: To asses SICUS characteristics of cel.ac disease patients. Patients and Methods: SICUS was performed using PEG 4000 as contrast agent. Twenty-three patients with cel.ac disease at the first diagnosis were enrol.ed and 30 heal.hy vol.nteers, matched for sex and age, were sel.cted as control.group. Cel.ac disease diagnosis was based on anti-gl.ten, anti-endomysium, and anti-transgl.taminase positivity as wel. as jejunal.histol.gy. The fol.owing seven echographic parameters were considered: l.quid endol.minal.content before contrast, l.op diameter, Kerckring’ s fol.s, peristal.ic waves, il.al.jejunal.zation, mesenteric l.mphoadenomegal.,and Doppl.r resistance index (RI) of mesenteric superior artery. Statistical.anal.sis was performed by Student’ s t test for unpaired data; one-way anal.sis of variance was used to correl.te echographic and histol.gic pictures. Resul.s: l.op diameter, Kerckring’ s fol. number, peristal.ic waves, and Doppl.r RI appeared to be significantl. different between cel.ac disease patients and control.. Additional.y, l.quid content, il.al.jejunal.zation, and mesenteric l.mphoadenomegal. were present onl. in the cel.acs (52.1% ,47.7% , and 95.6% , respectivel.), but not in control.. Onl. Doppl.r RI val.es significantl. correl.ted with the histol.gic degree of damage. Concl.sions: SICUS coul. be a rel.abl. and noninvasive technique to confirm a diagnosis of cel.ac disease performed using conventional.investigations. The possibil.ty of investigating the whol. smal. bowel.and the safety of repeating examinations coul. be useful.in the fol.ow-up of cel.ac patients.

关键词：乳糜泻小肠病变造影成像超声检查随访方法蠕动波肠结阻力指数重复检查组织学检查

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