检索结果-南通市图书馆

中华皮肤科杂志 2019年第12期52卷 940-941页

作者： Flament F pierre j Delhommeau K 不详

在自然老化和光老化的双重作用下,人类面部的各种特征会逐渐发生改变。此外,生活方式(吸烟、饮食、饮酒)和情绪(压力、悲伤、大笑、微笑等)可诱发、放大或加强一些面部征象,比如表情纹和皱纹。有文献显示,睡眠不足或睡眠质量差也可导致... 详细信息

在自然老化和光老化的双重作用下,人类面部的各种特征会逐渐发生改变。此外,生活方式(吸烟、饮食、饮酒)和情绪(压力、悲伤、大笑、微笑等)可诱发、放大或加强一些面部征象,比如表情纹和皱纹。有文献显示,睡眠不足或睡眠质量差也可导致其出现变化(从轻微到严重)。

关键词：自然老化睡眠质量睡眠不足光老化面部老化征象文献显示

The art of optical illusion

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The art of optical illusion

Saccharomyces cerevisiae CNCM I-3856 in irritable bowel syndrome: An individual subject meta-analysis

作者： Agata & pierre Toromanoff.

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

World journal of Gastroenterology 2017年第2期23卷 336-344页

作者： Amélie Cayzeele-Decherf Fanny Pélerin Sébastien Leuillet Benoit Douillard Béatrice Housez Murielle Cazaubiel Gunnard K jacobson Peter jüsten pierre Desreumaux Lesaffre Human Care Lesaffre Group Biofortis-Mérieux NutriS ciences Lesaffre Yeast Corporation Lesaffre Group CHU Lille Department of GastroenterologyClaude Huriez Hospital Lille University North of France INSERM U995

AIMTo confirm previous conclusions on Saccharomyces cerevisiae (S. cerevisiae) CNCM I-3856 for irritable bowel syndrome (IBS) *** individual patient data meta-analysis was performed on two randomized clinical trials studying the effect of S. cerevisiae CNCM I-3856 supplementation on gastrointestinal (GI) symptoms in IBS subjects. A total of 579 IBS subjects were included. Outcomes were the daily Likert scale scores of abdominal pain/discomfort and bloating [area under the curve (AUC) and weekly means], responder status, and bowel movements (stool frequency and consistency). Statistical analyses were conducted in Intent to Treat (ITT) population, IBS-C subjects and IBS-C subjects with an abdominal pain/discomfort score higher than or equal to 2 at baseline (“IBS-C ≥ 2 subpopulation”).RESULTSS. cerevisiae CNCM I-3856 significantly improved abdominal pain/discomfort and bloating during the second month of supplementation [AUC (W5-W8)] with improvement up to the minimal clinically relevant threshold of 10%: a 12.3% reduction of abdominal pain/discomfort in the ITT population compared to the Placebo group (P = 0.0134) has been observed. In the IBS-C ≥ 2 subpopulation, there were a 13.1% reduction of abdominal pain/discomfort and a 14.9% reduction of bloating compared to the Placebo group (P = 0.0194 and P = 0.0145, respectively). GI symptoms significantly decreased during supplementation but no statistical differences were reported between groups at the end of the supplementation period. Responder status was defined as a subject who experienced a decrease of 1 arbitrary unit (a.u.) or 50% of the abdominal discomfort score from baseline for at least 2 wk out of the last 4 wk of the study. A significant difference between groups was reported in the ITT population, when considering the first definition: subjects in the Active group had 1.510 higher odds to be a responder (reduction of 1 a.u. of abdominal pain/discomfort) comp

关键词： Irritable bowel syndrome Saccharomyces cerevisiae Constipation Abdominal pain Probiotics

The interaction of versican with its binding partners

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cell Research 2005年第7期15卷 483-494页

作者： David P. LA pierre,Albert j. YEE,Burton B. YANG Sunnybrook & Women’s College Health Sciences Centre 2075 Bayview Avenue Toronto M4N 3M5 Canada Department of Laboratory Medicine and Pathobiology University of Toronto Canada Sunnybrook & Women’s College Health Sciences Centre 2075 Bayview Avenue Toronto M4N 3M5 Canada Sunnybrook & Women’s College Health Sciences Centre 2075 Bayview Avenue Toronto M4N 3M5 Canada Department of Laboratory Medicine and Pathobiology University of Toronto Canada

Versican belongs to the family of the large aggregating chondroitin sulfate proteoglycans located primarily within theextracellular matrix (ECM). Versican, like other members of its family, has unique N- and C-terminal globular regions,each with multiple motifs. A large glycosaminoglycan-binding region lies between them. This review will begin byoutlining these structures, in the context of ECM proteoglycans. The diverse binding partners afforded to versican byvirtue of its modular design will then be examined. These include ECM components, such as hyaluronan, type Icollagen, tenascin-R, fibulin-1, and -2, fibrillin-1, fibronectin, P- and L-selectins, and chemokines. Versican also binds tothe cell surface proteins CD44, integrin β1, epidermal growth factor receptor, and P-selectin glycoprotein *** multiple interactors play important roles in cell behaviour, and the roles of versican in modulating such processesare discussed.

关键词： extracellular matrix proteoglycan G3 domain glycosaminoglycan interaction.

Textbook of Hepatology: From Basic Science to Clinical Practice, Third Edition 3

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

The complete collection of antiquities from the cabinet of Sir William Hamilton

2007年

作者： juan Rodés MD jean‐pierre Benhamou MD Andres T. Blei MD jürg Reichen MD Mario Rizzetto MD

ISBN: (数字)9780470691861

ISBN: (纸本)9781405127417

THE encyclopedic guide to hepatology – for consultation by clinicians and basic scientists Previously the Oxford Textbook of Clinical Hepatology , this two-volume textbook is now with Blackwell Publishing. It covers basic, clinical and translational science (converting basic science discoveries into the practical applications to benefit people). Edited by ten leading experts in the liver and biliary tract and their diseases, along with outstanding contributions from over 200 international clinicians, this text has global references, evidence and extensive subject matter – giving you the best science and clinical practice discussed by the best authors. It includes unique sections on: Symptoms and signs in liver disease Industrial diseases affecting the liver The effects of diseases of other systems on the liver The effects of liver diseases on other systems It's bigger and more extensive than other books and discusses new areas in more depth such as stem cells, genetics, genomics, proteomics, transplantation, mathematics and much more. Plus, it comes with a fully searchable CD ROM of the entire content. Click here to view a sample chapter on the liver and coagulation

关键词： LiverDiseases.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Physico-Chemical and Thermal Characterization of Some Lignocellulosic Fibres: Ananas comosus(AC), Neuropeltis acuminatas(NA) and Rhecktophyllum camerunense(RC)

作者： (1719-1805.)Hancarville pierre d'

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

journal of Minerals and Materials Characterization and Engineering 2020年第4期8卷 205-222页

作者： Achille Désiré Omgba Betene Fabien Ebanda Betene Florian Martoïa pierre j. j. Dumont Ateba Atangana pierre Marcel Anicet Noah Department of Mechanical Engineering ENSET University of Douala Douala Cameroon Laboratory of Mechanics University of Douala Douala Cameroon University of Lyon INSA-Lyon CNRS UMR5259 LaMCoS Lyon France

This paper focuses on the study of the physical, biochemical, structural, and thermal properties of plant fibres of Rhecktophyllum camerunense (RC), Neuropeltis acuminatas (NA) and Ananas comosus (AC) from the equatorial region of Cameroon. The traditional use of these fibres inspired researchers to investigated their properties. This study aims at improving the state of knowledge with a view to diversifying applications. The fibres are extracted by retting. Then, their apparent density was measured following the ASTM D792 standard and their water moisture absorption and moisture content were also evaluated. Their molecular structure was studied by ATR-FTIR spectroscopy. A quantitative analysis of the biochemical composition was performed according to the analytical technique for the pulp and paper industry (TAPPI). A TGA/DSC analysis was also performed. The results reveal that the AC, NA and RC fibres have densities of 1.26 ± 1.06, 0.846 ± 0.13 and 0.757 ± 0.08 g·cm-3 respectively. They are also hydrophilic with a water absorption rate of 188.64 ± 11.94%, 276.16% ± 8.07% and 198.17% ± 20%. They have a moisture content of 12.21%, 10.36% and 9.37%. The studied fibres exhibit functional groups that are related to the presence of hemicellulose, pectin, lignin and cellulose. The cellulose crystallinity index was found to be 67.99%, 46.5% and 59.72% respectively. The fibres under study have the following chemical composition: an extractive content of 3.07%, 14.77% and 8.74%;a pectin content of 4.15%, 7.69% and 3.45%;a hemicellulose content of 4.90%, 15.33% and 7.42%;a cellulose content of 68.11%, 36.08% and 65.15%;a lignin content of 12.01%, 25.15% and 16.2%;and an ash content of 0.27%, 1.53% and 0.47% respectively. The thermal transitions observed on the thermograms correlate with the TAPPI chemical composition. It is observed that these fibres are thermally stable up to temperatures of 200°C, 220°C and 285°C. These results ma

关键词： Lignocellulosic Fibre Rhecktophyllum camerunense Neuropeltis acuminatas Ananas comosus Biochemical Composition Cellulose Crystallinity Index Thermal Behaviour

Automated global delineation of human settlements from 40 years of Landsat satellite data archives

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Big Earth Data 2019年第2期3卷 140-169页

作者： Christina Corbane Martino Pesaresi Thomas Kemper Panagiotis Politis Aneta j.Florczyk Vasileios Syrris Michele Melchiorri Filip Sabo pierre Soille European Commission Joint Research CentreIspraItaly Arhs Developments S.A. Luxembourg Engineering S.p.a RomaItaly Arhs Developments Italia S.r.l. MilanoItaly

This paper presents the analysis of Earth Observation data records collected between 1975 and 2014 for assessing the extent and temporal evolution of the built-up surface in the frame of the Global Human Settlement Layer *** scale of the information produced by the study enables the assessment of the whole continuum of human settlements from rural hamlets to *** study applies enhanced processing methods as compared to the first production of the GHSL baseline *** major improvements include the use of a more refined learning set on built-up areas derived from Sentinel-1 data which allowed testing the added-value of incremental learning in big data ***,the new features of the GHSL built-up grids and the methods are described and compared with the previous ones using a reference set of building footprints for 277 areas of *** results show a gradual improvement in the accuracy measures with a gain of 3.6% in the balanced accuracy,between the first production of the GHSL baseline and the latest GHSL multitemporal built-up grids.A validation of the multitemporal component is also conducted at the global scale establishing the reliability of the built-up layer across time.

关键词： Built-up area landsat global human settlement layer machine learning validation

Anti-hepatitis C virus drugs and kidney

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World journal of Hepatology 2016年第32期8卷 1343-1353页

作者： Paul Carrier Marie Essig Marilyne Debette-Gratien Denis Sautereau Annick Rousseau pierre Marquet jérémie jacques Véronique Loustaud-Ratti U850 INSERM Université de Limoges Service d’Hépato-gastroentérologie CHU Limoges

Hepatitis C virus(HCV) mainly targets the liver but can also induce extrahepatic manifestations. The kidney may be impacted via an immune mediated mechanism or a cytopathic effect. HCV patients are clearly at a greater risk of chronic kidney disease(CKD) than uninfected patients are, and the presence of CKD increases mortality. Interferon-based therapies and ribavirin are difficult to manage and are poorly effective in endstage renal disease and hemodialysis. These patients should be given priority treatment with new direct anti-viral agents(DAAs) while avoiding peginterferon and ribavirin. The first results were convincing. To aid in the correct use of these drugs in patients with renal insufficiency, their pharmacokinetic properties and potential renal toxicity must be known. The renal toxicity of these new drugs was not a safety signal in clinical trials, and the drugs are generally efficient in these frail populations. These drugs are usually well tolerated, but recent cohort studies have demonstrated that these new regimens may be associated with renal side effects, especially when using sofosbuvir combinations. HCV, renal diseases and comorbidities are intimately linked. The close monitoring of renal function is required, particularly for at-risk patients(transplanted, HIV-coinfected, CKD, hypertensive or diabetic patients). New DAA regimens, which will soon be approved, will probably change the landscape.

关键词： Nephrotoxicity Hepatitis C Direct anti-viral agents Kidney End-stage renal disease