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Challenges and prospects for consumer acceptance of cultured meat

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Journal of Integrative Agriculture 2015年第2期14卷 285-294页

作者： Wim Verbeke pierre Sans Ellen J Van Loo Department of Agricultural Economics Ghent UniversityGent B-9000 Belgium INP-ENV Toulouse Toulouse 31076 France UR1303 ALISS INRA Ivry-sur-Seine 94205 France

Consumer acceptance of cultured meat is expected to depend on a wide diversity of determinants ranging from technologyrelated perceptions to product-specific expectations, and including wider contextual factors like media coverage, public involvement, and trust in science, policy and society. This paper discusses the case of cultured meat against this multitude of possible determinants shaping future consumer acceptance or rejection. The paper also presents insights from a primary exploratory study performed in April 2013 with consumers from Flanders（Belgium）（n=180）. The concept of cultured meat was only known（unaided） by 13% of the study participants. After receiving basic information about what cultured meat is, participants expressed favorable expectations about the concept. Only 9% rejected the idea of trying cultured meat, while two thirds hesitated and about quarter indicated to be willing to try it. The provision of additional information about the environmental benefits of cultured meat compared to traditional meat resulted in 43% of the participants indicating to be willing to try this novel food, while another 51% indicated to be ‘maybe＇ willing to do so. Price and sensory expectations emerged as major obstacles. Consumers eating mostly vegetarian meals were less convinced that cultured meat might be healthy, suggesting that vegetarians may not be the ideal primary target group for this novel meat substitute. Although exploratory rather than conclusive, the findings generally underscore doubts among consumers about trying this product when it would become available, and therefore also the challenge for cultured meat to mimic traditional meat in terms of sensory quality at an affordable price in order to become acceptable for future consumers.

关键词： acceptance artificial attitude consumer cultured in vitro meat synthetic

Germinal center-dependent and-independent immune responses of tumor-infiltrating B cells in human cancers

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Cellular & Molecular Immunology 2023年第9期20卷 1040-1050页

作者： Eve Playoust Romain Remark Eric Vivier pierre Milpied Marseille Université CNRSINSERMCentre d’Immunologie de Marseille-LuminyMarseilleFrance Innate Pharma MarseilleFrance

B cells play essential roles in immunity,mainly through the production of high affinity plasma cells(PCs)and memory B(Bmem)*** affinity maturation and differentiation of B cells rely on the integration of B-cell receptor(BCR)intrinsic and extrinsic signals provided by antigen binding and the microenvironment,*** recent years,tumor infiltrating B(TIL-B)cells and PCs(TIL-PCs)have been revealed as important players in antitumor responses in human cancers,but their interplay and dynamics remain largely *** lymphoid organs,B-cell responses involve both germinal center(GC)-dependent and GC-independent pathways for Bmem cell and PC *** maturation of BCR repertoires occurs in GC reactions with specific spatiotemporal dynamics of signal integration by B *** general,the reactivation of high-affinity Bmem cells by antigens triggers GC-independent production of large numbers of PC without BCR *** B-cell dynamics in immune responses requires the integration of multiple tools and readouts such as single-cell phenotyping and RNA-seq,in situ analyses,BCR repertoire analysis,BCR specificity and affinity assays,and functional ***,we review how those tools have recently been applied to study TIL-B cells and TIL-PC in different types of solid *** assessed the published evidence for different models of TIL-B-cell dynamics involving GC-dependent or GC-independent local responses and the resulting production of antigen-specific ***,we highlight the need for more integrative B-cell immunology studies to rationally investigate TIL-B cells as a leverage for antitumor therapies.

关键词： antibody tertiary lymphoid structure plasma cell germinal center cancer

New opportunities of dendrimers for theranostic approaches to personalized medicine

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Science China Materials 2018年第11期61卷 1365-1366页

作者： Jean-pierre Majoral Xiangyang Shi Serge Mignani Laboratoire de Chimie de Coordination Centre National de la Recherche Scientifique Toulouse France College of Chemistry Chemical Engineering and Biotechnology Donghua University Shanghai China CQM-Centro de Quimica da Madeira MMRG Universidade da Madeira Campus da Penteada 9020-105 Funchal Portugal

Theranostic nanomedicine paradigm, a combination of specific molecular diagnostic tests and specific targeted therapy, involves two topics:therapeutic product efficacies and diagnosis. The first topic concerns identified patients to be treated, whereas the second is to select patients for personalized medicine. Generally, nanotechnology allows developing theranostic strategy

关键词：特定分子诊断测试定向治疗发展现状医疗卫生行业

Finiteness of Mapping Degree Sets for 3-Manifolds

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Acta Mathematica Sinica,English Series 2011年第5期27卷 807-812页

作者： pierre DERBEZ Hong Bin SUN Shi Cheng WANG Centre de Mathematiques et d'Informatique Technopole de Chateau-Gombert 39 rue Frdddric Joliot-Curie-13453 Marseille Cedex 13 France Department of Mathematics Princeton University Princeton NJ 08544 USA Department of Mathematics Peking University Beijing 100871 P. R. China

By constructing certain maps, this note completes the answer of the question： For which closed orientable 3-manifold N, is the set of mapping degrees D（M, N） finite for any closed orientable 3-manifold M？

关键词： 3-Manifolds mapping degrees finiteness

Carleman Estimates for Parabolic Equations with Nonhomogeneous Boundary Conditions

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Chinese Annals of Mathematics,Series B 2009年第4期30卷 333-378页

作者： Oleg Yu IMANUVILOV Jean pierre PUEL Masahiro YAMAMOTO Department of Mathematics Colorado State University 101 Weber Building Fort Collins CO 80523USA Laboratoire de Mathematiques de Versailles Universit de Versailles-St. Quentin 45 Avenue des Etats Unis 78035 Versailles France. Department of Mathematical Sciences University of Tokyo Komaba Meguro Tokyo 153 Japan.

The authors prove a new Carleman estimate for general linear second order parabolic equation with nonhomogeneous boundary conditions. On the basis of this estimate, improved Carleman estimates for the Stokes system and for a system of parabolic equations with a penalty term are obtained. This system can be viewed as an approximation of the Stokes system.

关键词： Controllability Parabolic equations Carleman estimates

Behavioral constraints and the evolution of faithful social learning

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Current Zoology 2012年第2期58卷 307-318页

作者： Alberto ACERBI pierre O. JACQUET Claudio TENNIE Center for the Study of Cultural Evolution University of Stockholm 106 91 Stockholm Sweden Department of Psychology University of Bologna Bologna Italy INSERM U1028 CNRS UMR5292 Lyon Neuroscience Research Center ImpAct Team Lyon France Department of Developmental and Comparative Psychology Max Planck Institute for Evolutionary Anthropology Leipzig Germany

Behavioral ＂traditions＂, i.e. behavioral patterns that are acquired with the aid of social learning and that are relatively stable in a group, have been observed in several species. Recently, however, it has been questioned whether non-human social learning is faithful enough to stabilize those patterns. The observed stability could be interpreted as a result of various constraints that limit the number of possible alternative behaviors, rather than of the fidelity of transmission mechanisms. Those constraints can be roughly described as ＂internal＂, such as mechanical （bodily） properties or cognitive limitations and predispositions, and ＂ex- ternal＂, such as ecological availability or pressures. Here we present an evolutionary individual-based model that explores the re- lationships between the evolution of faithful social learning and behavioral constraints, represented both by the size of the beha- vioral repertoire and by the ＂shape＂ of the search space of a given task. We show that the evolution of high-fidelity transmission mechanisms, when associated with costs （e.g. cognitive, biomechanical, energetic, etc.）, is only likely if the potential behavioral repertoire of a species is large and if the search space does not provide information that can be exploited by individual learning. Moreover we show how stable behavioral patterns （＂traditions＂） can be achieved at the population level as an outcome of both high-fidelity and low-fidelity transmission mechanisms, given that the latter are coupled with a small behavioral repertoire or with a search space that provide substantial feedback. Finally, by introducing the possibility of environmental change, we show that intermediate rates of change favor the evolution of faithful social learning

关键词： Animal social learning Cultural evolution Cultural transmission Copying fidelity Individual based modeling

LiToTac: An Interactive-Interface Software for Finite Element Analysis of Multiple Contact Dynamics

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Computer Modeling in Engineering & Sciences 2019年第1期118卷 111-137页

作者： Lei Peng Zhiqiang Feng pierre Joli Christine Renaud School of Mechanics and Engineering Southwest Jiaotong UniversityChengdu610031China Laboratory of Mechanics and Energetics UniversitéParis-SaclayEvry91020France.

In order to investigate the mechanical behavior of systems with complex architecture and a large number of contacting bodies,a finite element software,named LiToTac,has been developed by using the object-oriented programming *** software,with an interactive graphical user interface,is able to handle highly non-linear problems including multiple contacts and large *** importantly,the contact detection based on a hybrid three-stages methodology can be performed automatically,which is more efficient than the common strategies of pre-defining contact zones in commercial FEM software like ANSYS,ABAQUS,*** addition,the contact solver in LiToTac is portable between dynamic and quasi-static codes and can accurately solve contact coupled with friction in a reduced *** numerical examples are carried out to illustrate the functionality and capacity of the software package.

关键词： Finite element software object-oriented programming automatic contact detection multiple contact dynamics.

Solving the Dyson-Schwinger equation around its first singularities in the Borel plane

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Frontiers of physics 2016年第6期11卷 25-30页

作者： Clavier, pierre J. Bellon, Marc P. Sorbonne Universites UPMC Univ Paris 06 UMR 7589 LPTHE Paris France (GRID:grid.5805.8) (ISNI:***) CNRS UMR 7589 LPTHE Paris France (GRID:grid.4444.0) (ISNI:0000 0001 2112 9282)

The Dyson-Schwinger equation of the massless Wess-Zumino model is written as an equation over the anomalous dimension of the theory. Its asymptotic behavior is derived and the procedure to compute the perturbations of this asymptotic behavior is detailed. This procedure uses ill-defined objects. To solve this, the Dyson-Schwinger equation is rewritten for the Borel plane. It is shown that the ill- defined procedure in the physical plane can be applied in the Borel plane. Other results obtained in the Borel plane are stated and the proof for one result is described.

关键词： Dyson-Schwinger equation Wess-Zumino model Borel transform

***-an interactive climate analysis web platform

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International Journal of Digital Earth 2021年第3期14卷 338-356页

作者： Laura Zepner pierre Karrasch Felix Wiemann Lars Bernard Chair of Geoinformatics Technische Universität DresdenDresdenGermany AED-SICAD GmbH BonnGermany

This article describes the conception and implementation of a web platform which uses special charts and maps for climate monitoring and *** first it gives an overview of related web applications and their advantages and *** is followed by a basic introduction of current technologies and methods for working with climate data,geospatial web services and visualization ***,the implementation based on prior defined requirements is presented and its strengths and limitations are *** application provides several basic charts for climate analysis,as well as a more complex one which uses a standardized visualization concept which is suitable for comparing different local climates(Walter-LiethStandard).The charts are based on different interpolated datasets with global coverage as well as data from the Global Historical Climate Network(GHCN).Overall,the application enables users to generate individual historical climate charts from the beginning of the twentieth century until present day.

关键词： Climate monitoring WalterLieth charts Köppen-Geiger classification user interface design education information visualization