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The role of electrocardiographic imaging in patient selection for cardiac resynchronization therapy

Journal of Geriatric Cardiology 2021年第10期18卷 836-843页

作者： Saer Abu-Alrub Marc Strik Peter Huntjens Michel Haïssaguerre Romain Eschalier pierre bordachar Sylvain Ploux Cardiology Department Clermont University Hospital(CHU)Clermont-FerrandClermont-FerrandFrance Cardio-Thoracic Unit Bordeaux University Hospital(CHU)Pessac-BordeauxFrance IHU Liryc Electrophysiology and Heart Modeling InstituteFondation Bordeaux UniversitéPessac-BordeauxFrance Division of Cardiology Washington UniversitySt.LouisMissouriUSA

Cardiac resynchronization therapy(CRT)has been shown to improve symptoms,left ventricle(LV)performance and long-term survival in patients with heart failure with re-duced ejection fraction(HFrEF)and delayed ventricular activation.[1]CRT is currently recom-mended in symptomatic patients with LV ejection fraction of≤35%,and ventricular conduction dis-order manifested as left bundle branch block(LBBB)>149 ms,and should be considered in LBBB>129 ms or non-LBBB QRS duration>150 ms.

关键词： ventricular synchronization ventricle

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A MEDIAN FOLLOW-UP OF TWENTY-TWO MONTHS FOR CARDIOVERTER DEFIBRILLATOR IMPLANTATION IN SYMPTOMATIC OR ASYMPTOMATIC PATIENTS WITH BRUGADA SYNDROME

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Medical Bulletin of Shanghai Jiaotong University 2010年第1期22卷 47-53页

作者：蔡煦苏静英黄剑锋沈卫峰 Stéphane Garrigue pierre bordachar Jacques Cl menty Department of Cardiology Ruijin HospitalSchool of MedicineShanghai Jiaotong University Department of Cardiac Pacing and Clinical Electrophysiology Hpital Cardiologique du Haut-LévêqueUniversity Bordeaux Ⅱ19 Avenue de Magellan

Objective To explore the outcome of patients with Brugada syndrome by remedial or prophylactic implantable cardioverter defibrillator （ ICD ） for ventricular tachyarrhythmia. Methods Sixteen single chamber ICDs and 5 double chamber ICDs in 21 consecutive patients [ 17 males, 4 females; mean age, （ 36 ± 11） years ] with Brugada syndrome were involved. Fifteen patients with spontaneous or induced ventricular tachycardia/ventricular fibrillation （VT/VF） received the remedial and prophylactic ICD implantation. Six patients only with positive family history or syncope accepted the ICD implantation for prophylaxis. Results After a median follow-up of （22.3 ± 13. 4） months, all patients were alive. One patient was suspected with febrile syndrome due to endocarditis on the auricular face of the lead of defibrillator 18 months after 1CD implantation and disappearance of vegetation was found after receiving one-month antibiotic treatment. Nine appropriate ICD interventions took place in 3 individuals with documented spontaneous ventricular arrhythmias. Multivariable analysis suggested that occurrence of appropriate interventions was related to the spontaneous ventricular arrhythmias （ P 〈 0. 0001 ）. Eleven inappropriate ICD interventions occurred in 3 patients for atrial fibrillation or atrial flutter with rapid ventricular rate. Multivariable analysis suggested that occurrence of inappropriate interventions was related to documented spontaneous supraventricular arrhythmias （P 〈 O. 0062 ）. All appropriate interventions and inappropriate interventions occurred within six months after ICD implantation. Conclusion Appropriate interventions may associate to spontaneous ventricular arrhythmias before 1CD implantation in patients with Brugada syndrome. Patients may suffer from inappropriate ICD intervention for supraventricular arrhythmias with rapid ventricular rate when they had a history of supraventricular arrhythmias.

关键词： Brugada syndorme implantable cardioverter defibrillator

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