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Dense-Structured Network Based Bearing Remaining Useful Life Prediction System

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Computer Modeling in Engineering & Sciences 2022年第10期131卷 133-151页

作者： Ping-Huan Kuo Ting-Chung Tseng Po-chien Luan Her-Terng yau Department of Mechanical Engineering National Chung Cheng UniversityChiayi62102Taiwan Advanced Institute of Manufacturing with High-Tech Innovations(AIM-HI) National Chung Cheng UniversityChiayi62102Taiwan

This work is focused on developing an effective method for bearing remaining useful life *** method is useful in accurately predicting the remaining useful life of bearings so that machine damage,production outage,and human accidents caused by unexpected bearing failure can be *** study uses the bearing dataset provided by FEMTO-ST Institute,Besancon,*** study starts with the exploration of neural networks,based on which the biaxial vibration signals are modeled and *** paper introduces pre-processing of bearing vibration signals,neural network model training and adjustment of training *** model is trained by optimizing model parameters and verifying its performance through *** proposed model’s superiority is also confirmed through a comparison with other *** this study,the neural network model is trained with various types of bearing data and can successfully predict the remaining useful *** algorithm proposed in this study achieves a prediction accuracy of coefficient of determination as high as 0.99.

关键词： Bearing neural network remaining useful life prediction machine learning

Ensemble Model for Spindle Thermal Displacement Prediction of Machine Tools

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Computer Modeling in Engineering & Sciences 2023年第10期137卷 319-343页

作者： Ping-Huan Kuo Ssu-Chi Chen Chia-Ho Lee Po-chien Luan Her-Terng yau Department of Mechanical Engineering National Chung Cheng UniversityChiayi62102Taiwan Advanced Institute of Manufacturing with High-Tech Innovations(AIM-HI) National Chung Cheng UniversityChiayi62102Taiwan

Numerous factors affect the increased temperature of a machine tool, including prolonged and high-intensity usage,tool-workpiece interaction, mechanical friction, and elevated ambient temperatures, among others. Consequently,spindle thermal displacement occurs, and machining precision suffers. To prevent the errors caused by thetemperature rise of the Spindle fromaffecting the accuracy during themachining process, typically, the factory willwarm up themachine before themanufacturing ***, if there is noway to understand the tool spindle’sthermal deformation, the machining quality will be greatly affected. In order to solve the above problem, thisstudy aims to predict the thermal displacement of the machine tool by using intelligent algorithms. In the practicalapplication, only a few temperature sensors are used to input the information into the prediction model for realtimethermal displacement prediction. This approach has greatly improved the quality of tool ***,each algorithm has different performances in different environments. In this study, an ensemble model is used tointegrate Long Short-TermMemory (LSTM) with Support VectorMachine (SVM). The experimental results showthat the prediction performance of LSTM-SVM is higher than that of other machine learning algorithms.

关键词： Thermal displacement ensemble model LSTM milling machine spindle

Pancreatic melatonin enhances anti-tumor immunity in pancreatic adenocarcinoma through regulating tumor-associated neutrophils infiltration and NETosis

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Acta Pharmaceutica Sinica B 2023年第4期13卷 1554-1567页

作者： yau-tuen Chan Hor-yue Tan Yuanjun Lu Cheng Zhang chien-shan Cheng Junyu Wu Ning Wang Yibin Feng School of Chinese Medicine the University of Hong KongHong KongChina Centre for Chinese Herbal Medicine Drug Development School of Chinese MedicineHong Kong Baptist UniversityHong KongChina Department of Traditional Chinese Medicine Shanghai Jiaotong UniversitySchool of Medicine Affiliated Ruijin HospitalShanghai 200025China

Tumor microenvironment contributes to poor prognosis of pancreatic adenocarcinoma(PAAD)*** regulation could improve *** is an endogenous hormone that delivers multiple *** we showed that pancreatic melatonin level is associated with patients'*** PAAD mice models,melatonin supplementation suppressed tumor growth,while blockade of melatonin pathway exacerbated tumor *** anti-tumor effect was independent of cytotoxicity but associated with tumor-associated neutrophils(TANs),and TANs depletion reversed effects of *** induced TANs infiltration and activation,therefore induced cell apoptosis of PAAD *** arrays revealed that melatonin had minimal impact on neutrophils but induced secretion of Cxcl2 from tumor *** of Cxcl2 in tumor cells abolished neutrophil migration and ***-induced neutrophils presented an N1-like anti-tumor phenotype,with increased neutrophil extracellular traps(NETs)causing tumor cell apoptosis through cell-to-cell *** analysis revealed that this reactive oxygen species(ROS)-mediated inhibition was fueled by fatty acid oxidation(FAO)in neutrophils,while FAO inhibitor abolished the anti-tumor *** of PAAD patient specimens revealed that CXCL2 expression was associated with neutrophil ***2,or TANs,combined with NET marker,can better predict patients'***,we discovered an anti-tumor mechanism of melatonin through recruiting N1-neutrophils and beneficial NET formation.

关键词： Pancreatic adenocarcinoma Melatonin Anti-tumor immunity Tumor-associated neutrophils Tumor microenvironment CXCL2 Neutrophil extracellular traps NETosis

Evaluation of contrast-enhanced computed tomographic colonography in detection of local recurrent colorectal cancer

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World Journal of Gastroenterology 2006年第1期12卷 123-126页

作者： yau-Tong You Chung-Rong Chang chien Jeng-Yi Wang Koon-Kwan Ng Jinn-Shiun Chen Reiping Tang Jy-Ming Chiang chien-Yuh Yeh Pao-Shiu Hsieh Division of Colon and Rectal Surgery Chang Gung Memorial HospitalLin-KouTaiwanChina Division of Colon and Rectal Surgery Chang Gung Memorial HospitalJia-YiTaiwanChina Department of Radiology Chang Gung Memorial HospitalKee-LungTaiwanChina

AIM： TO evaluate the diagnostic accuracy, sensitivity, specificity of contrast-enhanced computed tomographic colonography in detecting local recurrence of colorectal cancer. METHODS： From January 2000 to December 2004, 434 patients after potentially curative resection for invasive colorectal cancer were followed up for a period ranging from 20 to 55 mo. Eighty of the four hundred and thirty-four patients showing strong clinical evidence for recurring colorectal cancer during the last followup were enrolled in this study. Each patient underwent contrast-enhanced computed tomographic colonography and colonoscopy on the same day. Any lesions, biopsies, identified during the colonoscopic examination, immediate complications and the duration of the procedure were recorded. The results of contrast-enhanced computed tomographic colonography were evaluated by comparing to those of colonoscopy, surgical finding, and clinical follow-up. RESULTS： Contrast-enhanced computed tomographic colonography had a sensitivity of 100%, a specificity of 83% and an overall accuracy of 94% in detecting local recurrent colorectal cancer. CONCLUSION： Conventional colonoscopy and contrastenhanced tomographic colonography can complement each other in detecting local recurrence of colorectal cancer.

关键词： Computed tomographic colonography Recurrent colorectal cancer

The role of technological innovation,carbon finance,green energy,environmental awareness and urbanization towards carbon neutrality:Evidence from novel CUP-FM CUP-BC estimations

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Geoscience Frontiers 2024年第4期15卷 347-358页

作者： FengSheng chien School of Finance Fuzhou University of International Studies and TradeFuzhouChina Faculty of Business City University of MacaoMacaoChina Carbon Economy Research Center Fuzhou University of International Studies and TradeFuzhouChina

After COP21,various economies start putting efforts to fulfill the pledge and achieve carbon *** doing so,scholars highlight several essential factors that can curb carbon *** this lieu,the current study analyzes the role of technological innovation,carbon finance,environmental awareness,urbanization,and green energy like renewable energy consumption(REC)and renewable energy output(REO)on carbon neutrality in E7 countries covering the time span of *** employing CUP-FM and CUP-BC,it is revealed that technological innovation,carbon finance,environmental awareness,urbanization,REC,and REO have a positive connection with carbon neutrality in E7 *** study provides guidelines to the policymakers in developing policies regarding to obtain carbon neutrality using technological innovation,carbon finance,environmental awareness,and green energy.

关键词： Technological innovation Carbon finance Environmental awareness Urbanization Green energy Carbon neutrality

Turbulence and cavitation models for time-dependent turbulent cavitating flows

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Acta Mechanica Sinica 2011年第4期27卷 473-487页

作者： chien-Chou Tseng Department of Mechanical Engineering University of Michigan

Cavitation typically occurs when the fluid pressure is lower than the vapor pressure at a local thermodynamic state, and the flow is frequently unsteady and turbulent. To assess the state-of-the-art of computational capabilities for unsteady cavitating flows, different cavitation and turbulence model combinations are conducted. The selected cavitation models include several widely-used models including one based on phenomenological argument and the other utilizing interface dynamics. The k-e turbulence model with additional implementation of the filter function and density correction function are considered to reduce the eddy viscosity according to the computed turbulence length scale and local fluid density respectively. We have also blended these alternative cavitation and lustrate that the eddy viscosity turbulence treatments, to ilnear the closure region can significantly influence the capture of detached cavity. From the experimental validations regarding the force analysis, frequency, and the cavity visualization, no single model combination performs best in all aspects. Furthermore, the implications of parameters contained in different cavitation models are investigated. The phase change process is more pronounced around the detached cavity, which is better illustrated by the interfacial dynamics model. Our study provides insight to aid further modeling development.

关键词： Cavitation Turbulence model Cavitationmodel Hybrid model

Double-lined M dwarf eclipsing binaries from Catalina Sky Survey and LAMOST

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Research in Astronomy and Astrophysics 2017年第2期17卷 29-34页

作者： chien-Hsiu Lee chien-Cheng Lin Subaru Telescope National Astronomical Observatory of Japan Shanghai Astronomical Observatory Chinese Academy of Sciences

Eclipsing binaries provide a unique opportunity to determine fundamental stellar properties. In the era of wide-field cameras and all-sky imaging surveys, thousands of eclipsing binaries have been reported through light curve classification, yet their basic properties remain unexplored due to the ex- tensive efforts needed to follow them up spectroscopically. In this paper we investigate three M2-M3 type double-lined eclipsing binaries discovered by cross-matching eclipsing binaries from the Catalina Sky Survey with spectroscopically classified M dwarfs from the Large Sky Area Multi-Object Fiber Spectroscopic Telescope survey data release one and two. Because these three M dwarf binaries are faint, we further acquire radial velocity measurements using GMOS on the Gemini North telescope with R ~4000, enabling us to determine the mass and radius of individual stellar components. By jointly fitting the light and radial velocity curves of these systems, we derive the mass and radius of the primary and secondary components of these three systems, in the range between 0.28-0.42 MQ and 0.29-0.67 R, respectively. Future observations with a high resolution spectrograph will help us pin down the uncertainties in their stellar parameters, and render these systems benchmarks to study M dwarfs, providing inputs to improving stellar models in the low mass regime, or establishing an empirical mass-radius relation for M dwarf stars.

关键词： (stars) binaries eclipsing

The culture and establishment of embryonic germ(EG)cell lines from Chinese mini swine

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Cell Research 2003年第3期13卷 195-202页

作者： HSIAO chien TSUNG Shanghai Institutes for Biologcal Sciences of Biochemistry and Cell Biology Chinese Academy of Sciences Shanghai 200031 Institute Laboratory of Embryonic Stem Cell China

As a part of a basic research project on Xeno-transplantion,we have been engaged in the derivation ofembryonic stem cell lines from Chinese mini ***,we reported for the first time the establishmentof two porcine EG cell lines(BPEG1 and BPEG2)from primordial germ cells of genital ridges of a 28 anda 27 d embryos *** pluripotent nature has been identified by colony morphology,markercharacterization as well as well as by in vitro and in vivo *** porcine EG cells are potentiallyuseful for further basic studies.

关键词： primordial germ cells EG cells porcine Chinese mini swine.

On Three Differential Equations Associated with Chebyshev Polynomials of Degrees 3,4 and 6

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Acta Mathematica Sinica,English Series 2017年第1期33卷 21-36页

作者： Li chien SHEN Department of Mathematics University of Florida Gainesville FL 32611-8105

We shall study the differential equation y^l2=Tn（y）-（1-2μ2）;where μ2 is a constant, Tn（x） are the Chebyshev polynomials with n = 3,4,6. The solutions of the differential equations will be expressed explicitly in terms of the Weierstrass elliptic function which can be used to construct theories of elliptic functions based on 2F1 （1/4, 3/4; 1; z）, 2F1 （l/3, 2/3; 1; z）, 2F1 （1/6, 5/6; 1; z） and provide a unified approach to a set of identities of Rmanujan involving these hypergeometric functions.

关键词： Chebyshev polynomials Eisenstein series Jacobi theta functions Weierstrass ellipticfunction