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Keratoconus in a patient with Alport syndrome: A case report

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World Journal of Clinical Cases 2019年第19期7卷 3012-3017页

作者： Majid Moshirfar David F Skanchy Aaron T Gomez Yasmyne C Ronquillo Benjamin Buckner phillip C Hoopes John A.Moran Eye Center Department of Ophthalmology and Visual SciencesUniversity of Utah School of MedicineSalt Lake CityUT 84101United States Utah Lions Eye Bank Salt Lake CityUT 84101United States Hoopes Durrie Rivera Research Center Hoopes VisionDraperUT 84020United States Kellogg Eye Center Department of OphthalmologyUniversity of Michigan Medical SchoolAnn ArborMI 48103United States The University of Texas Rio Grande Valley School of Medicine EdinburgTX 78542United States

BACKGROUND Known ocular manifestations of Alport syndrome include features such as anterior lenticonus and fleck retinopathy. Reports of keratoconus in such patients are limited. We report tomographic findings consistent with keratoconus in a patient with Alport *** SUMMARY A 52-year-old female was referred to our ophthalmology clinic with decreased vision and increased tearing. She was diagnosed with stage Ⅲ Alport syndrome two years prior. Upon examination she was found to have average keratometries of 48D bilaterally with tomographic evidence of *** Although a rare presentation, concurrent Alport syndrome and keratoconus should be considered when reviewing the ocular health of Alport syndrome patients and appropriate management steps should be taken upon the diagnosis.

关键词： Alport syndrome,Keratoconus Type Ⅳ collagen COL4A genes Corneal ectasia Case report

Irrigated pinto bean crop stress and yield assessment using ground based low altitude remote sensing technology

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Information Processing in Agriculture 2019年第4期6卷 502-514页

作者： Rakesh Ranjan Abhilash KChandel Lav R.Khot Haitham YBahlol Jianfeng Zhou Rick ABoydston phillip NMiklas Department of Biological Systems Engineering Washington State UniversityPullmanWAUSA Center for Precision and Automated Agricultural Systems IARECWashington State UniversityProsserWAUSA USDA-ARS Grain Legume Genetics and Physiology Research Unit ProsserWA USA

The pinto bean is one of widely consumed legume crop that constitutes over 42%of the U.S dry bean ***,limited studies have been conducted in past to assess its quantitative and qualitative yield *** remote sensing technologies can help in such ***,this study evaluates the role of ground-based multispectral imagery derived vegetation indices(VIs)for irrigated the pinto bean stress and yield *** were eight cultivars of the pinto bean grown under conventional and strip tillage treatments and irrigated at 52%and 100%of required *** data was acquired using a five-band multispectral imager at early,mid and late growth *** used 25 broadband VIs were derived to capture crop stress traits and yield *** component analysis and Spearman’s rank correlation tests were conducted to identify key VIs and their correlation(rs)with abiotic stress at each growth *** difference vegetation index,nonlinear vegetation index(NLI),modified NLI and infrared percentage vegetation index(IPVI)were consistent in accounting the stress response and crop yield at all growth stages(rs>0.60,coefficient of determination(R2):0.50–0.56,P<0.05).Ten other VIs significantly accounted for crop stress at early and late ***,identified key VIs may be helpful to growers for precise crop management decision making and breeders for crop stress response and yield assessments.

关键词： Pinto bean Multispectral imaging Vegetation indices Stress assessment Yield potential

Strategies for Dealing with Gang Activity in Urban Communities

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Journal of Philosophy Study 2015年第10期5卷 525-529页

作者： phillip Neely Saint Leo University

As disturbing as youth and gun violence is, it is not hard to reduce the mortality rate because it is preventable. The information provided in this research will help to get policies waiting to be reviewed by legislators, and any new proposal that reaches the appropriate legislative chamber, reviewed without obstacles and will help to prevent youth violence. Upon completion of this research, the study shows that rates of youth violence have decreased based on programs implemented at the state government level with a stronger juvenile justice system holding offenders accountable to ensure public safety and reduce youth violence and victimization. The study shows that community and school involvement with law enforcement and government agencies are some of the strategies needed to help reduce gun violence and rebuild communities.

关键词： gang activity urban communities juvenile delinquency violence

The surviving sepsis campaign： 2013 and beyond

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Chinese Medical Journal 2013年第10期126卷 1803-1805页

作者： R. phillip Dellinger Cooper Medical School of Rowan University Division of Critical Care Medicine Cooper University Hospital Camden N J USA

The 2012 revision of the Surviving Sepsis Campaign.＂ International Guideless for Management of SevereSepsis and Septic Shock was recently published （February 2013） in Critical Care Medicine and Intensive Care Medicine.1,2 The effort to create this document occurred over two years and likely represents the most comprehensive buy-in of any international medical guidelines to date with 30 sponsoring organizations. Included in this list of sponsoring organizations is the Chinese Society of Critical Care Medicine-China Medical Association and the Chinese Society of Critical Care Medicine. The evidence based medicine （EBM） grading system continues to evolve under the leadership of the Grades of Recommendation Assessment Development and Evaluation Group （GRADE Group）, based in Canadal Each recommendation is graded based on quality of evidence and strength of recommendation.

关键词： severe sepsis septic shock guideline

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热力学遗传算法计算效率的改进

软件学报 2008年第7期19卷 1613-1622页

作者：应伟勤李元香 SHEU phillip C-Y 武汉大学软件工程国家重点实验室湖北武汉430072 Department of Electrical Engineering and Computer Science University of CaliforniaIrvineCA 92697USA

热力学遗传算法(thermodynamical genetic algorithms,简称TDGA)借鉴固体退火过程中能量与熵的竞争模式来协调GA中"选择压力"和"种群多样性"之间的冲突.然而TDGA目前极高的计算代价限制了其应用.为了提高TDGA的计算效率,首先定义一种等... 详细信息

热力学遗传算法(thermodynamical genetic algorithms,简称TDGA)借鉴固体退火过程中能量与熵的竞争模式来协调GA中"选择压力"和"种群多样性"之间的冲突.然而TDGA目前极高的计算代价限制了其应用.为了提高TDGA的计算效率,首先定义一种等级熵(rating-based entropy,简称RE)度量方法,它能以较小的计算成本度量种群中个体适应值的分散程度.然后引入分量热力学替换规则(component thermodynamical replacement,简称CTR),有效地降低了替换规则的复杂度.同时也证明了CTR规则具有驱动种群自由能近似最速下降的能力.在0-1背包问题上的实验结果表明,RE方法和CTR规则在保持TDGA良好的性能与稳定性的同时,极大地提高了其计算效率.

关键词：遗传算法热力学计算效率多样性度量潜换规则

Time-lapse videography reveals different morphokinetic profiles of human embryos displaying direct or reverse cleavage at different stages of development: A retrospective sibling embryo study

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Asian pacific Journal of Reproduction 2020年第6期9卷 261-266页

作者： Chloé Brits Katie Feenan Vince Chapple phillip L.Matson Yan-he Liu School of Medical and Health Science Edith Cowan UniversityJoondalupWestern AustraliaAustralia Fertility Specialists of Western Australia ClaremontWestern AustraliaAustralia Fertility North Joondalup Private HospitalJoondalupWestern AustraliaAustralia School of Human Sciences University of Western AustraliaCrawleyWestern AustraliaAustralia Monash IVF Group SouthportQueenslandAustralia

Objective:To investigate morphokinetic characteristics of embryos displaying either reverse cleavage or direct cleavage during the first,second or third cleavage ***:A total of 167 in vitro fertilization and/or intracytoplasmic sperm injection treatment cycles undertaken by 167 women[aged(35.0±4.6)years]were included for reverse cleavage analysis,and a total of 167 in vitro fertilization and/or intracytoplasmic sperm injection treatment cycles undertaken by 167 women[aged(33.8±4.3)years]were included for direct cleavage analysis in this *** a sibling-embryo design,morphokinetic profiles(both before and after the onset of abnormal event)of embryos displaying reverse cleavage(n=241)or direct cleavage(n=244)were compared with their unaffected siblings(the controls)in the first,second and third cell cycles(n=32,n=142,n=562;n=195,n=412,n=205,respectively),at different developmental stages up to day ***:Direct cleavage embryos demonstrated significantly delayed cleavage rates prior to the event regardless of developmental stage of the occurrence,while reverse cleavage embryos showed similar cleavage rates to their unaffected *** event,direct cleavage embryos sped up cleavage rates while reverse cleavage embryos slowed ***:Altered morphokinetic profiles are displayed by direct cleavage embryos both before and after their occurrence and reverse cleavage embryos after the occurrence,which could potentially confound morphokinetic comparisons if not separated from their unaffected sibling *** study is warranted in order to fully understand the biological mechanisms of such events.

关键词： Time-lapse Direct cleavage Reverse cleavage Morphokinetics Cleavage abnormality

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温哥华公寓

城市环境设计 2019年第2期118卷 210-219页

作者： Carl McDonald Melissa Bauld Aaron Mark Alan Tansey Alex Wu Alexandra Gustafsson Alina Tamosiunaite Amina Blacksher Aran Coakley Arash Adel Ahmadian Armen Menendian Barbora Srpkova Ben Zunkeler Benjamin Caldwell Benjamin Novacinski Bennett Gale Birk Daugaard Blake Theodore Smith Brian Foster Brian Rome Carolien Schippers Christopher James Malcolm Jr. Christopher Junkin Christopher Tron David Brown David Dottelonde Deborah Campbell Doug Stechschulte Douglass Alligood Edward Yung Elena Bresciani Filip Milovanovic Francesca Portesine Gabriel Hernandez Solano Gabriel Jewell-Vitale Hector Garcia Ivy Hume Jan Leenknegt Janice Rim John Kim Josiah Poland Julian Liang Julianne Gola Julie Kaufman Karol Bogdan Borkowski Kurt Nieminen Lauren Turner Lorenz Krisai Lucio Santos Marcella Martinez Martin Voelkle Matthew Dlugosz Megan Ng Michael Robert Taylor Otilia Pupezeanu Paula Domka phillip macdougall Ryan Yang Sean Franklin Sebastian Grogaard Simon Scheller Spencer Hayden Taylor Fulton Terrence Chew Terry Lallak Thomas Smith Tianqi Zhang Tobias Hjortdal Tran Le Valentina Mele Xinyu Wang Yaziel Juarbe Yoanna Shivarova Zach Walters Zhifei Xu Andrew Latreille Glotman Simpson Urban YVR 运小红

温哥华公寓的建成预示着这个年轻的城市正在打开城市政策制定的新局面。它将成为从Granville大桥进入温哥华市中心的城市大门。塔楼和群房的设计是对新城市主义地域类型中的"温哥华主义"建筑的全新解读,配合一座纤细的塔楼,试图保留城... 详细信息

温哥华公寓的建成预示着这个年轻的城市正在打开城市政策制定的新局面。它将成为从Granville大桥进入温哥华市中心的城市大门。塔楼和群房的设计是对新城市主义地域类型中的"温哥华主义"建筑的全新解读,配合一座纤细的塔楼,试图保留城市视觉通廊并激活步行通道。住宅塔楼借助高度和毗邻河流的地理位置,是唯一可以同时享受水景和山景的建筑,坐拥温哥华广袤的自然风光。

关键词：温哥华平面图 Dialog 立面图

Saline and Heparinised Flush in Maintaining Patency ofArterial Catheters in Adult PatientsmA SystematicReview

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Journal of Health Science 2014年第12期2卷 571-583页

作者： Jasmine Lee phillip Della National Heart Centre Singapore Singapore 169609 Curtin University GPO Box U1987 Perth 6845 Western Australia

This paper compares the effectiveness of normal saline and heparinised saline as a flushing solution in maintaining patencyof arterial catheters. Use of heparin as a flushing solution in maintaining patency of intra- arterial catheters has been a recognizedpractice. Due to its anticoagulation properties, heparin can cause side effects like heparin-induced thromhocytopenia in hypersensitivepatients. The alternative, normal saline solution increases the accuracy of patients＇ coagulation status and enhances safer clinicalpractice. A systematic search was conducted at Cochrane Library, Medline, CINAHL, OVID and Joanna Briggs Institute. Reviewperiod covered from 1990 to 2011. Methodological validity of included studies was evaluated using SIGN grading checklists fromScottish Intercollegiate Guidelines Network. There is inconsistent evidence and sample sizes were too small to allow statisticalsignificance to be achieved. Meta-analysis was performed for 2 studies; results revealed that heparinised saline offers no addedadvantage over normal saline. There is insufficient evidence to support the use of heparinised saline for flushing arterial catheters. Arigorous research design is needed to determine variables known to influence patency of arterial catheters. Sound clinical judgementmust be exercised in situations that require the need of heparinised saline.

关键词： Heparinised saline, normal saline, arterial catheters, patency, nursing.

A Uniqueness Theorem for Linear Wave Equations

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Journal of Partial Differential Equations 2013年第4期26卷 289-299页

作者： WHITMAN phillip YU Pin Department of Mathematics Princeton University Princeton 08540 New JerseyUSA. Mathematical Sciences Center Tsinghua University Haidian District Beijing 100084China.

The classical Huygens＇ principle asserts that the initial data of a wave equa- tion determines the wave propagation in the domain of dependence of the support of the data. We provide a converse version of this theorem.

关键词： Wave equation uniqueness.